F Kamel

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. doi request reprint Dietary fat intake, pesticide use, and Parkinson's disease
    Freya Kamel
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health NIH, Department of Health and Human Services DHHS, Research Triangle Park, NC, USA Electronic address
    Parkinsonism Relat Disord 20:82-7. 2014
  2. pmc Pesticide exposure and amyotrophic lateral sclerosis
    Freya Kamel
    Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Neurotoxicology 33:457-62. 2012
  3. pmc Association of pesticide exposure with neurologic dysfunction and disease
    Freya Kamel
    National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709, USA
    Environ Health Perspect 112:950-8. 2004
  4. pmc Neurobehavioral performance and work experience in Florida farmworkers
    Freya Kamel
    Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Environ Health Perspect 111:1765-72. 2003
  5. pmc Amyotrophic lateral sclerosis, lead, and genetic susceptibility: polymorphisms in the delta-aminolevulinic acid dehydratase and vitamin D receptor genes
    Freya Kamel
    National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Environ Health Perspect 111:1335-9. 2003
  6. pmc Association of lead exposure with survival in amyotrophic lateral sclerosis
    Freya Kamel
    Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Environ Health Perspect 116:943-7. 2008
  7. ncbi request reprint Lead exposure and amyotrophic lateral sclerosis
    Freya Kamel
    National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Epidemiology 13:311-9. 2002
  8. pmc Recruiting a community sample in collaboration with farmworkers
    F Kamel
    National Institute of Environmental Health Sciences, 111 TW Alexander Dr, Research Triangle Park, NC 27709, USA
    Environ Health Perspect 109:457-9. 2001
  9. ncbi request reprint Retinal degeneration in licensed pesticide applicators
    F Kamel
    Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Am J Ind Med 37:618-28. 2000
  10. ncbi request reprint Association of cigarette smoking with amyotrophic lateral sclerosis
    F Kamel
    National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Neuroepidemiology 18:194-202. 1999

Detail Information

Publications35

  1. doi request reprint Dietary fat intake, pesticide use, and Parkinson's disease
    Freya Kamel
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health NIH, Department of Health and Human Services DHHS, Research Triangle Park, NC, USA Electronic address
    Parkinsonism Relat Disord 20:82-7. 2014
    ..Dietary fat intake may modify Parkinson's disease (PD) risk directly or by altering the response to environmental neurotoxicants including pesticides...
  2. pmc Pesticide exposure and amyotrophic lateral sclerosis
    Freya Kamel
    Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Neurotoxicology 33:457-62. 2012
    ..The latter results are novel but based on a small number of cases and require replication in other populations...
  3. pmc Association of pesticide exposure with neurologic dysfunction and disease
    Freya Kamel
    National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709, USA
    Environ Health Perspect 112:950-8. 2004
    ..Major unresolved issues include the relative importance of acute and chronic exposure, the effect of moderate exposure in the absence of poisoning, and the relationship of pesticide-related neurotoxicity to neurodegenerative disease...
  4. pmc Neurobehavioral performance and work experience in Florida farmworkers
    Freya Kamel
    Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Environ Health Perspect 111:1765-72. 2003
    ..We conclude that long-term experience of farm work is associated with measurable deficits in cognitive and psychomotor function...
  5. pmc Amyotrophic lateral sclerosis, lead, and genetic susceptibility: polymorphisms in the delta-aminolevulinic acid dehydratase and vitamin D receptor genes
    Freya Kamel
    National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Environ Health Perspect 111:1335-9. 2003
    ..These findings suggest that genetic susceptibility conferred by polymorphisms in ALAD may affect ALS risk, possibly through a mechanism related to internal lead exposure...
  6. pmc Association of lead exposure with survival in amyotrophic lateral sclerosis
    Freya Kamel
    Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Environ Health Perspect 116:943-7. 2008
    ..Reasons for the variability in survival among ALS cases are unknown but may include exposure to environmental neurotoxicants...
  7. ncbi request reprint Lead exposure and amyotrophic lateral sclerosis
    Freya Kamel
    National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Epidemiology 13:311-9. 2002
    ..Previous interview-based studies have suggested that exposure to neurotoxicants including metals might be related to ALS...
  8. pmc Recruiting a community sample in collaboration with farmworkers
    F Kamel
    National Institute of Environmental Health Sciences, 111 TW Alexander Dr, Research Triangle Park, NC 27709, USA
    Environ Health Perspect 109:457-9. 2001
    ..Collaboration with the community is essential to the success of such a project, and community characteristics can affect response rates...
  9. ncbi request reprint Retinal degeneration in licensed pesticide applicators
    F Kamel
    Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Am J Ind Med 37:618-28. 2000
    ..Retinal degeneration is the leading cause of visual impairment in older adults, but little is known about its relationship to neurotoxic exposures...
  10. ncbi request reprint Association of cigarette smoking with amyotrophic lateral sclerosis
    F Kamel
    National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Neuroepidemiology 18:194-202. 1999
    ..The association of cigarette smoking with ALS was not affected by adjusting for alcohol use. In contrast, the weak relationship of ALS with alcohol use was apparently due to confounding by smoking...
  11. pmc Neurologic symptoms in licensed private pesticide applicators in the agricultural health study
    Freya Kamel
    National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC 27709, USA
    Environ Health Perspect 113:877-82. 2005
    ....
  12. ncbi request reprint Neurologic symptoms in licensed pesticide applicators in the Agricultural Health Study
    F Kamel
    National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, PO Box 12233, Research Triangle Park, NC 27709, USA
    Hum Exp Toxicol 26:243-50. 2007
    ..These results suggest that neurologic symptoms are associated with cumulative exposure to moderate levels of organophosphate and organochlorine insecticides, regardless of recent exposure or history of poisoning...
  13. ncbi request reprint Lead exposure as a risk factor for amyotrophic lateral sclerosis
    F Kamel
    National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC 27709, USA
    Neurodegener Dis 2:195-201. 2005
    ..Most previous case-control studies found an association of ALS with self-reported occupational exposure to lead, with increased risks of 2- to >4-fold. However, these results may have been affected by recall bias...
  14. pmc Incident diabetes and pesticide exposure among licensed pesticide applicators: Agricultural Health Study, 1993-2003
    M P Montgomery
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC 27709, USA
    Am J Epidemiol 167:1235-46. 2008
    ..Long-term exposure from handling certain pesticides, in particular, organochlorine and organophosphate insecticides, may be associated with increased risk of diabetes...
  15. ncbi request reprint Exposure opportunities of families of farmer pesticide applicators
    B C Gladen
    National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Am J Ind Med 34:581-7. 1998
    ..Families of farmer pesticide applicators have unusual opportunities for exposure, directly or indirectly, to pesticides. These exposures are not well characterized...
  16. ncbi request reprint Retinal degeneration and other eye disorders in wives of farmer pesticide applicators enrolled in the agricultural health study
    Ellen F Kirrane
    CODA, Inc, Durham, NC 27709, USA
    Am J Epidemiol 161:1020-9. 2005
    ..These findings suggest that exposure to some fungicides and other pesticides may increase the risk of retinal degeneration and warrant further investigation...
  17. pmc Association between blood lead and the risk of amyotrophic lateral sclerosis
    Fang Fang
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, USA
    Am J Epidemiol 171:1126-33. 2010
    ..32). These results extend earlier findings by accounting for bone turnover in confirming the association between elevated blood lead level and higher risk of ALS...
  18. ncbi request reprint Pesticide exposure and self-reported Parkinson's disease in the agricultural health study
    F Kamel
    National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Am J Epidemiol 165:364-74. 2007
    ..4). Prevalent PD was not associated with overall pesticide use. This study suggests that exposure to certain pesticides may increase PD risk. Findings for specific chemicals may provide fruitful leads for further investigation...
  19. pmc Smoking duration, intensity, and risk of Parkinson disease
    H Chen
    Epidemiology Branch, National Institute of Environmental Health Sciences, 111 T W Alexander Dr, PO Box 12233, Mail Drop A3 05, Research Triangle Park, NC 27709, USA
    Neurology 74:878-84. 2010
    ..To evaluate the relative importance of smoking duration vs intensity in reducing the risk of Parkinson disease (PD)...
  20. ncbi request reprint Dietary intake of calcium, magnesium and antioxidants in relation to risk of amyotrophic lateral sclerosis
    M P Longnecker
    Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle, NC 27709, USA
    Neuroepidemiology 19:210-6. 2000
    ..Overall, these dietary factors were not related to risk of ALS, though modestly protective associations were suggested for magnesium and lycopene...
  21. pmc Effects of self-reported health conditions and pesticide exposures on probability of follow-up in a prospective cohort study
    Martha P Montgomery
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709, USA
    Am J Ind Med 53:486-96. 2010
    ..We investigated the potential for selection bias due to non-participation in the follow-up of a large prospective cohort study...
  22. pmc Disease and injury among participants in the Agricultural Health Study
    A Blair
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Executive Plaza South, Room 8118, Bethesda, Maryland 20892, USA
    J Agric Saf Health 11:141-50. 2005
    ..The study can provide data to address many health issues in the agricultural community. The study investigators welcome collaboration with interested scientists...
  23. ncbi request reprint Health effects of chronic pesticide exposure: cancer and neurotoxicity
    Michael C R Alavanja
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Rockville, Maryland 20892, USA
    Annu Rev Public Health 25:155-97. 2004
    ..Improving epidemiology studies and integrating this information with toxicology data will allow the human health risks of pesticide exposure to be more accurately judged by public health policy makers...
  24. pmc Head injury and amyotrophic lateral sclerosis
    Honglei Chen
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA
    Am J Epidemiol 166:810-6. 2007
    ..7, 95 percent CI: 1.3, 2.2). In this study population, physical injuries to other body parts, including the trunk, arms, or legs, were not related to ALS risk. These data support the notion that head injury may increase the risk of ALS...
  25. ncbi request reprint VEGF promoter haplotype and amyotrophic lateral sclerosis (ALS)
    Paul D Terry
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health DHHS, Research Triangle Park, NC 27709, USA
    J Neurogenet 18:429-34. 2004
    ..7 - 13.4), consistent with the findings of the previous study. Given the wide confidence interval, our findings should be interpreted cautiously...
  26. ncbi request reprint Mortality among participants in the agricultural health study
    Aaron Blair
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD, USA
    Ann Epidemiol 15:279-85. 2005
    ..This analysis of the Agricultural Health Study cohort assesses the mortality experience of licensed pesticide applicators and their spouses...
  27. pmc Depression and the subsequent risk of Parkinson's disease in the NIH-AARP Diet and Health Study
    Fang Fang
    Epidemiology Branch, Department of Health and Human Services, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709, USA
    Mov Disord 25:1157-62. 2010
    ..The results suggest that depression may either be a very early symptom of PD or share common etiological factors with PD...
  28. ncbi request reprint Integrating epidemiology and toxicology in neurotoxicity risk assessment
    William K Boyes
    National Health and Environmental Effects Research Laboratory, Office of Research and Development, US Environmental Protection Agency, Research Triangle Park, NC 27711, USA
    Hum Exp Toxicol 26:283-93. 2007
    ..An appropriate blend of scientific information from toxicology and epidemiology studies is necessary to evaluate potential human risks of exposure to neurotoxic substances...
  29. pmc Workplace exposures and the risk of amyotrophic lateral sclerosis
    Fang Fang
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health DHHS, Research Triangle Park, NC 27709, USA
    Environ Health Perspect 117:1387-92. 2009
    ..Occupation has been suggested to play a role in amyotrophic lateral sclerosis (ALS) etiology, but detailed information on the importance of specific workplace exposures is lacking...
  30. pmc Overall diet quality and age-related macular degeneration
    Martha P Montgomery
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC, USA
    Ophthalmic Epidemiol 17:58-65. 2010
    ..To examine overall diet quality in relation to advanced age-related macular degeneration (AMD)...
  31. pmc Genes and Environmental Exposures in Veterans with Amyotrophic Lateral Sclerosis: the GENEVA study. Rationale, study design and demographic characteristics
    Silke Schmidt
    Center for Human Genetics, Duke University Medical Center, Durham, NC 27710, USA
    Neuroepidemiology 30:191-204. 2008
    ....
  32. pmc Mortality among pesticide applicators exposed to chlorpyrifos in the Agricultural Health Study
    Won Jin Lee
    Department of Preventive Medicine, College of Medicine, Korea University, Seoul, Korea
    Environ Health Perspect 115:528-34. 2007
    ..Chlorpyrifos is one of the most widely used organophosphate insecticides in the United States. Although the toxicity of chlorpyrifos has been extensively studied in animals, the epidemiologic data are limited...
  33. pmc Depression and pesticide exposures in female spouses of licensed pesticide applicators in the agricultural health study cohort
    Cheryl Beseler
    Colorado Injury Control Research Center, Department of Psychology, Colorado State University, Fort Collins, Colorado 80523, USA
    J Occup Environ Med 48:1005-13. 2006
    ..This nested case-control study evaluated the association between depression and pesticide exposure among women...
  34. pmc Declaring chemicals "not carcinogenic to humans" requires validation, not speculation
    Ronald L Melnick
    Environ Health Perspect 111:A203-4. 2003
  35. pmc Maternal age, exposure to siblings, and risk of amyotrophic lateral sclerosis
    Fang Fang
    Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
    Am J Epidemiol 167:1281-6. 2008
    ..Although the strength of the observed associations was modest, these results provided further support for the theory that early life exposures might contribute to the disease pathogenesis...