Research Topics
Species | F KamelSummaryAffiliation: National Institutes of Health Country: USA Publications
| Collaborators
|
Detail Information
Publications
Pesticide exposure and amyotrophic lateral sclerosisFreya Kamel
Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
Neurotoxicology 33:457-62. 2012..The latter results are novel but based on a small number of cases and require replication in other populations...- Association of pesticide exposure with neurologic dysfunction and diseaseFreya Kamel
National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709, USA
Environ Health Perspect 112:950-8. 2004..Major unresolved issues include the relative importance of acute and chronic exposure, the effect of moderate exposure in the absence of poisoning, and the relationship of pesticide-related neurotoxicity to neurodegenerative disease... - Neurobehavioral performance and work experience in Florida farmworkersFreya Kamel
Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
Environ Health Perspect 111:1765-72. 2003..We conclude that long-term experience of farm work is associated with measurable deficits in cognitive and psychomotor function... - Amyotrophic lateral sclerosis, lead, and genetic susceptibility: polymorphisms in the delta-aminolevulinic acid dehydratase and vitamin D receptor genesFreya Kamel
National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
Environ Health Perspect 111:1335-9. 2003..These findings suggest that genetic susceptibility conferred by polymorphisms in ALAD may affect ALS risk, possibly through a mechanism related to internal lead exposure... 
Lead exposure and amyotrophic lateral sclerosisFreya Kamel
National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
Epidemiology 13:311-9. 2002..Previous interview-based studies have suggested that exposure to neurotoxicants including metals might be related to ALS...- Recruiting a community sample in collaboration with farmworkersF Kamel
National Institute of Environmental Health Sciences, 111 TW Alexander Dr, Research Triangle Park, NC 27709, USA
Environ Health Perspect 109:457-9. 2001..Collaboration with the community is essential to the success of such a project, and community characteristics can affect response rates... - Association of lead exposure with survival in amyotrophic lateral sclerosisFreya Kamel
Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
Environ Health Perspect 116:943-7. 2008..Reasons for the variability in survival among ALS cases are unknown but may include exposure to environmental neurotoxicants... - Retinal degeneration in licensed pesticide applicatorsF Kamel
Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
Am J Ind Med 37:618-28. 2000..Retinal degeneration is the leading cause of visual impairment in older adults, but little is known about its relationship to neurotoxic exposures... - Association of cigarette smoking with amyotrophic lateral sclerosisF Kamel
National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
Neuroepidemiology 18:194-202. 1999..The association of cigarette smoking with ALS was not affected by adjusting for alcohol use. In contrast, the weak relationship of ALS with alcohol use was apparently due to confounding by smoking... - Neurologic symptoms in licensed private pesticide applicators in the agricultural health studyFreya Kamel
National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC 27709, USA
Environ Health Perspect 113:877-82. 2005.... - Neurologic symptoms in licensed pesticide applicators in the Agricultural Health StudyF Kamel
National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, PO Box 12233, Research Triangle Park, NC 27709, USA
Hum Exp Toxicol 26:243-50. 2007..These results suggest that neurologic symptoms are associated with cumulative exposure to moderate levels of organophosphate and organochlorine insecticides, regardless of recent exposure or history of poisoning... - Lead exposure as a risk factor for amyotrophic lateral sclerosisF Kamel
National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC 27709, USA
Neurodegener Dis 2:195-201. 2005..Most previous case-control studies found an association of ALS with self-reported occupational exposure to lead, with increased risks of 2- to >4-fold. However, these results may have been affected by recall bias... - Incident diabetes and pesticide exposure among licensed pesticide applicators: Agricultural Health Study, 1993-2003M P Montgomery
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC 27709, USA
Am J Epidemiol 167:1235-46. 2008..Long-term exposure from handling certain pesticides, in particular, organochlorine and organophosphate insecticides, may be associated with increased risk of diabetes... - Exposure opportunities of families of farmer pesticide applicatorsB C Gladen
National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
Am J Ind Med 34:581-7. 1998..Families of farmer pesticide applicators have unusual opportunities for exposure, directly or indirectly, to pesticides. These exposures are not well characterized... - Retinal degeneration and other eye disorders in wives of farmer pesticide applicators enrolled in the agricultural health studyEllen F Kirrane
CODA, Inc, Durham, NC 27709, USA
Am J Epidemiol 161:1020-9. 2005..These findings suggest that exposure to some fungicides and other pesticides may increase the risk of retinal degeneration and warrant further investigation... - Association between blood lead and the risk of amyotrophic lateral sclerosisFang Fang
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, USA
Am J Epidemiol 171:1126-33. 2010..32). These results extend earlier findings by accounting for bone turnover in confirming the association between elevated blood lead level and higher risk of ALS... - Smoking duration, intensity, and risk of Parkinson diseaseH Chen
Epidemiology Branch, National Institute of Environmental Health Sciences, 111 T W Alexander Dr, PO Box 12233, Mail Drop A3 05, Research Triangle Park, NC 27709, USA
Neurology 74:878-84. 2010..To evaluate the relative importance of smoking duration vs intensity in reducing the risk of Parkinson disease (PD)... - Pesticide exposure and self-reported Parkinson's disease in the agricultural health studyF Kamel
National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
Am J Epidemiol 165:364-74. 2007..4). Prevalent PD was not associated with overall pesticide use. This study suggests that exposure to certain pesticides may increase PD risk. Findings for specific chemicals may provide fruitful leads for further investigation... - Dietary intake of calcium, magnesium and antioxidants in relation to risk of amyotrophic lateral sclerosisM P Longnecker
Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle, NC 27709, USA
Neuroepidemiology 19:210-6. 2000..Overall, these dietary factors were not related to risk of ALS, though modestly protective associations were suggested for magnesium and lycopene... - Effects of self-reported health conditions and pesticide exposures on probability of follow-up in a prospective cohort studyMartha P Montgomery
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709, USA
Am J Ind Med 53:486-96. 2010..We investigated the potential for selection bias due to non-participation in the follow-up of a large prospective cohort study... - Disease and injury among participants in the Agricultural Health StudyA Blair
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Executive Plaza South, Room 8118, Bethesda, Maryland 20892, USA
J Agric Saf Health 11:141-50. 2005..The study can provide data to address many health issues in the agricultural community. The study investigators welcome collaboration with interested scientists... - Health effects of chronic pesticide exposure: cancer and neurotoxicityMichael C R Alavanja
Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Rockville, Maryland 20892, USA
Annu Rev Public Health 25:155-97. 2004..Improving epidemiology studies and integrating this information with toxicology data will allow the human health risks of pesticide exposure to be more accurately judged by public health policy makers... - Head injury and amyotrophic lateral sclerosisHonglei Chen
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA
Am J Epidemiol 166:810-6. 2007..7, 95 percent CI: 1.3, 2.2). In this study population, physical injuries to other body parts, including the trunk, arms, or legs, were not related to ALS risk. These data support the notion that head injury may increase the risk of ALS... - VEGF promoter haplotype and amyotrophic lateral sclerosis (ALS)Paul D Terry
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health DHHS, Research Triangle Park, NC 27709, USA
J Neurogenet 18:429-34. 2004..7 - 13.4), consistent with the findings of the previous study. Given the wide confidence interval, our findings should be interpreted cautiously... - Mortality among participants in the agricultural health studyAaron Blair
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD, USA
Ann Epidemiol 15:279-85. 2005..This analysis of the Agricultural Health Study cohort assesses the mortality experience of licensed pesticide applicators and their spouses... - Depression and the subsequent risk of Parkinson's disease in the NIH-AARP Diet and Health StudyFang Fang
Epidemiology Branch, Department of Health and Human Services, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709, USA
Mov Disord 25:1157-62. 2010..The results suggest that depression may either be a very early symptom of PD or share common etiological factors with PD... - Workplace exposures and the risk of amyotrophic lateral sclerosisFang Fang
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health DHHS, Research Triangle Park, NC 27709, USA
Environ Health Perspect 117:1387-92. 2009..Occupation has been suggested to play a role in amyotrophic lateral sclerosis (ALS) etiology, but detailed information on the importance of specific workplace exposures is lacking... - Integrating epidemiology and toxicology in neurotoxicity risk assessmentWilliam K Boyes
National Health and Environmental Effects Research Laboratory, Office of Research and Development, US Environmental Protection Agency, Research Triangle Park, NC 27711, USA
Hum Exp Toxicol 26:283-93. 2007..An appropriate blend of scientific information from toxicology and epidemiology studies is necessary to evaluate potential human risks of exposure to neurotoxic substances... 
Overall diet quality and age-related macular degenerationMartha P Montgomery
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC, USA
Ophthalmic Epidemiol 17:58-65. 2010..To examine overall diet quality in relation to advanced age-related macular degeneration (AMD)...- Genes and Environmental Exposures in Veterans with Amyotrophic Lateral Sclerosis: the GENEVA study. Rationale, study design and demographic characteristicsSilke Schmidt
Center for Human Genetics, Duke University Medical Center, Durham, NC 27710, USA
Neuroepidemiology 30:191-204. 2008.... - Depression and pesticide exposures in female spouses of licensed pesticide applicators in the agricultural health study cohortCheryl Beseler
Colorado Injury Control Research Center, Department of Psychology, Colorado State University, Fort Collins, Colorado 80523, USA
J Occup Environ Med 48:1005-13. 2006..26; 95% confidence interval [CI] = 1.72-6.19) but not low (OR = 1.09; CI = 0.91-1.31) or high (OR = 1.09; 95% CI = 0.91-1.31) cumulative pesticide exposure. CONCLUSION: Pesticide poisoning may contribute to risk of depression... - Mortality among pesticide applicators exposed to chlorpyrifos in the Agricultural Health StudyWon Jin Lee
Department of Preventive Medicine, College of Medicine, Korea University, Seoul, Korea
Environ Health Perspect 115:528-34. 2007..Chlorpyrifos is one of the most widely used organophosphate insecticides in the United States. Although the toxicity of chlorpyrifos has been extensively studied in animals, the epidemiologic data are limited... - Declaring chemicals "not carcinogenic to humans" requires validation, not speculationRonald L Melnick
Environ Health Perspect 111:A203-4. 2003 - Maternal age, exposure to siblings, and risk of amyotrophic lateral sclerosisFang Fang
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
Am J Epidemiol 167:1281-6. 2008..Although the strength of the observed associations was modest, these results provided further support for the theory that early life exposures might contribute to the disease pathogenesis...