Research Topics
Genomes and GenesSpecies | F KamangarSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
High levels of carcinogenic polycyclic aromatic hydrocarbons in mate drinksFarin Kamangar
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
Cancer Epidemiol Biomarkers Prev 17:1262-8. 2008..We conducted this study to determine whether drinking mate could lead to substantial exposure to polycyclic aromatic hydrocarbons (PAH), including known carcinogens, such as benzo[a]pyrene...
Obesity and hypertension in an Iranian cohort study; Iranian women experience higher rates of obesity and hypertension than American womenHossein Bahrami
Digestive Disease Research Center, Tehran University of Medical Sciences, Tehran, Iran
BMC Public Health 6:158. 2006..We determined the prevalence of overweight, obesity, and hypertension in a large cohort of Iranians and compared age-adjusted rates with the rates in the US...
Higher urine 1-hydroxy pyrene glucuronide (1-OHPG) is associated with tobacco smoke exposure and drinking maté in healthy subjects from Rio Grande do Sul, BrazilRenato B Fagundes
Universidade Federal de Santa Maria, Departamento de Clinica Medica, Centro de Ciencias da Saude, Santa Maria, RS, Brazil
BMC Cancer 6:139. 2006..The aims of the current study were to investigate the degree and sources of PAH exposure of the inhabitants of this region of southern Brazil...
Lung cancer chemoprevention: a randomized, double-blind trial in Linxian, ChinaFarin Kamangar
Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Room 3034, Bethesda, MD 10892 7232, USA
Cancer Epidemiol Biomarkers Prev 15:1562-4. 2006..Supplementation with combinations of vitamins and minerals at nutrient-repletion levels for 5.25 years did not reduce lung cancer mortality in this nutrient-inadequate population in Linxian, China...
Polymorphisms in inflammation-related genes and risk of gastric cancer (Finland)Farin Kamangar
Division of Cancer Epidemiology and Genetics, US National Cancer Institute, Bethesda, MD 20892 7232, USA
Cancer Causes Control 17:117-25. 2006..Our results do not support the hypothesis that polymorphisms in genes involved in the inflammatory response confer differences in gastric cancer risk among different individuals...
Esophageal cancer in Northeastern Iran: a reviewFarin Kamangar
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA
Arch Iran Med 10:70-82. 2007..This article reviews the studies conducted on esophageal squamous cell cancer in this area and summarizes the data on epidemiologic patterns, incidence trends, and etiology of esophageal squamous cell cancer in this province...
Ginseng intake and gastric cancer risk in the Shanghai Women's Health Study cohortFarin Kamangar
Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Room 3034, Bethesda, MD 20892-7232, USA
Cancer Epidemiol Biomarkers Prev 16:629-30. 2007
Interleukin-1B polymorphisms and gastric cancer risk--a meta-analysisFarin Kamangar
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, 6120 Executive Boulevard, Room 3034, Bethesda, MD 20892 7232, USA
Cancer Epidemiol Biomarkers Prev 15:1920-8. 2006..The overall associations between IL-1B or IL-1RN proinflammatory polymorphisms and gastric cancer were null but several studies showed an association. The sources of this variation are unclear...
High exposure to polycyclic aromatic hydrocarbons may contribute to high risk of esophageal cancer in northeastern IranFarin Kamangar
Cancer Prevention Studies Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 21218, USA
Anticancer Res 25:425-8. 2005..The northeastern region of Iran has some of the highest rates of esophageal squamous cell carcinoma (ESCC) in the world...
Serum pepsinogens and risk of esophageal squamous dysplasiaFarin Kamangar
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7232, USA
Int J Cancer 124:456-60. 2009..03. Lower serum PGI/II ratio was linearly associated with higher risk of ESD. This result is consistent with recent findings that gastric atrophy may increase the risk of ESCC...
Opposing risks of gastric cardia and noncardia gastric adenocarcinomas associated with Helicobacter pylori seropositivityFarin Kamangar
Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Rm 3034, Bethesda, MD 20892 7232, USA
J Natl Cancer Inst 98:1445-52. 2006..pylori strain differences are less clear. We conducted a prospective nested case-control study of H. pylori serology to address these questions...
Environmental causes of esophageal cancerFarin Kamangar
Division of Cancer Epidemiology and Genetics, National Cancer Institute NIH, 6120 Executive Blvd, Bethesda, MD 20892 7232, USA
Gastroenterol Clin North Am 38:27-57, vii. 2009..Results of studies investigating other factors are also discussed...
Helicobacter pylori and oesophageal and gastric cancers in a prospective study in ChinaF Kamangar
Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Rm 3034, Bethesda, MD 20892 7232, USA
Br J Cancer 96:172-6. 2007....
Human papillomavirus serology and the risk of esophageal and gastric cancers: results from a cohort in a high-risk region in ChinaFarin Kamangar
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
Int J Cancer 119:579-84. 2006..4). For HPV 73, these figures were 1.3 (0.6-2.5), 1.2 (0.6-2.3) and 0.9 (0.4-2.1). The results of this study do not support a major role for HPV 16, HPV 18 and HPV 73 in the etiology of esophageal and gastric cancers in Linxian, China...
Genetic polymorphisms in three Iranian populations with different risks of esophageal cancer, an ecologic comparisonAlireza Sepehr
The US National Cancer Institute, Bethesda, MD, USA
Cancer Lett 213:195-202. 2004..We conclude that it is unlikely that variations in these polymorphic genes are major contributors to the high incidence of EC among Turkomans in Iran...
Plasma pepsinogens, antibodies against Helicobacter pylori, and risk of gastric cancer in the Shanghai Women's Health Study CohortC C Abnet
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Executive Plaza South, Room 320, 6120 Executive Boulevard, MSC 7232, Rockville, MD 20852, USA
Br J Cancer 104:1511-6. 2011..We tested the association between gastric cancer and plasma pepsinogens and antibodies against Helicobacter pylori in a case-control study nested in a prospective cohort...
Epstein-Barr virus serology and gastric cancer incidence and survivalJ Koshiol
Cancer Prevention Fellowship, Division of Cancer Prevention, National Cancer Institute, 6120 Executive Blvd, MSC 7236, Bethesda, MD, USA
Br J Cancer 97:1567-9. 2007..High EBV nuclear antigen titres were associated with longer survival in cardia cancer cases, possibly due to chance...
Poor oral health as a risk factor for esophageal squamous dysplasia in northeastern IranAlireza Sepehr
Cancer Prevention Studies Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 21218, USA
Anticancer Res 25:543-6. 2005..01). CONCLUSION: Our results are consistent with two other published studies that have shown oral health as a risk factor for ESCC. The high incidence of ESCC in northeastern Iran may be partly attributable to poor oral health...
Vitamin E intake and risk of esophageal and gastric cancers in the NIH-AARP Diet and Health StudySarah Carman
NEB DCEG, National Cancer Institute, Bethesda, MD 20892 7232, USA
Int J Cancer 125:165-70. 2009..An increase of 71 mg/day (half the interquartile range) in supplemental vitamin E had an hazard ratio (95% confidence interval) of 0.92 (0.85-1.00) and the p value for trend in the quartile analysis was 0.015...
Tea, coffee, carbonated soft drinks and upper gastrointestinal tract cancer risk in a large United States prospective cohort studyJ S Ren
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States
Eur J Cancer 46:1873-81. 2010..In summary, hot tea intake was inversely associated with pharyngeal cancer, and coffee was directly associated with gastric cardia cancer, but was inversely associated with EADC during some follow-up periods...
Non-steroidal anti-inflammatory drugs and risk of gastric and oesophageal adenocarcinomas: results from a cohort study and a meta-analysisC C Abnet
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20852, USA
Br J Cancer 100:551-7. 2009..64 (0.52-0.80), 0.82 (0.65-1.04), and 0.64 (0.52-0.79), respectively. The corresponding numbers for other NSAIDs were 0.68 (0.57-0.81), 0.80 (0.67-0.95), and 0.65 (0.50-0.85), respectively...
Fruits, vegetables, and antioxidants and risk of gastric cancer among male smokersMehdi Nouraie
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892-7232, USA
Cancer Epidemiol Biomarkers Prev 14:2087-92. 2005..Tocopherols were associated with higher risk of GCC, whereas dietary intake of fruits, vitamin C, tocopherols, and lycopene seemed protective for GNCC...
The influence of genetic polymorphisms in Ahr, CYP1A1, CYP1A2, CYP1B1, GST M1, GST T1 and UGT1A1 on urine 1-hydroxypyrene glucuronide concentrations in healthy subjects from Rio Grande do Sul, BrazilChristian C Abnet
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, EPS 320, MSC 7232, Rockville, MD 20852, USA
Carcinogenesis 28:112-7. 2007..10; and a model combining both exposure and genotype information had a total r2 of 0.33. Our results suggest that CYP1B1 genotypes are strongly associated with urine 1-OHPG concentrations in this population...
Tooth loss and lack of regular oral hygiene are associated with higher risk of esophageal squamous cell carcinomaChristian C Abnet
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Executive Plaza South, Room 320, 6120 Executive Boulevard, MSC 7232, Rockville, MD 20852, USA
Cancer Epidemiol Biomarkers Prev 17:3062-8. 2008..Our results are consistent with several previous analyses in other high-risk populations...
Serum pepsinogen level, atrophic gastritis and the risk of incident pancreatic cancer--a prospective cohort studyAdeyinka O Laiyemo
Cancer Prevention Fellowship Program, Office of Preventive Oncology, National Cancer Institute NCI, National Institutes of Health NIH, Bethesda, MD 20892, USA
Cancer Epidemiol 33:368-73. 2009..We hypothesized that low SPGI level may be associated with an increased risk of pancreatic cancer and be a useful biomarker for the disease...
Atrophic gastritis and the risk of incident colorectal cancerAdeyinka O Laiyemo
Cancer Prevention Fellowship Program, Office of Preventive Oncology, National Cancer Institute NCI, National Institutes of Health NIH, Bethesda, MD, USA
Cancer Causes Control 21:163-70. 2010..We prospectively examined the association of atrophic gastritis, a pre-malignant condition for gastric cancer and long-term sequelae common to many exposure factors, and the risk of incident CRC...
No role for human papillomavirus in esophageal squamous cell carcinoma in ChinaJill Koshiol
Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD 20852 7248, USA
Int J Cancer 127:93-100. 2010..HPV DNA contamination cannot be ruled out as an explanation for high HPV prevalence in ESCC tissue studies with less stringent tissue procurement and processing protocols...
The gastric cardia is not a target for human papillomavirus-induced carcinogenesisJill Koshiol
Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Room 7070, Rockville, MD 20852 7248, USA
Cancer Epidemiol Biomarkers Prev 19:1137-9. 2010..Given the availability of an effective HPV vaccine and its potential to prevent HPV-associated cancer, we decided to evaluate the prevalence of HPV DNA in GCA...
Reliability and validity of opiate use self-report in a population at high risk for esophageal cancer in Golestan, IranChristian C Abnet
Cancer Prevention Studies Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
Cancer Epidemiol Biomarkers Prev 13:1068-70. 2004..To assess the reliability and validity of self-reported opium use in a rural Iranian population at high risk for esophageal cancer in preparation for a large cohort study...
Serum pepsinogens and Helicobacter pylori in relation to the risk of esophageal squamous cell carcinoma in the alpha-tocopherol, beta-carotene cancer prevention studyMichael B Cook
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health DHHS, 6120 Executive Boulevard, Bethesda, MD 20852 7234, USA
Cancer Epidemiol Biomarkers Prev 19:1966-75. 2010..Helicobacter pylori can induce gastric atrophy in humans, which in turn increases gastric cancer risk. Whether H. pylori and gastric atrophy also affect the risk of esophageal squamous cell carcinoma (ESCC), however, remains unresolved...
Cigarette smoking and adenocarcinomas of the esophagus and esophagogastric junction: a pooled analysis from the international BEACON consortiumMichael B Cook
Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health DHHS, 6120 Executive Blvd, Bethesda, MD 20852 7234, USA
J Natl Cancer Inst 102:1344-53. 2010....
Tooth loss is associated with increased risk of gastric non-cardia adenocarcinoma in a cohort of Finnish smokersChristian C Abnet
Cancer Prevention Studies Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland 20892, USA
Scand J Gastroenterol 40:681-7. 2005..pylori seropositivity...
Self-reported goiter is associated with a significantly increased risk of gastric noncardia adenocarcinoma in a large population-based Chinese cohortChristian C Abnet
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
Int J Cancer 119:1508-10. 2006..37 (0.97, 1.94). Our findings are consistent with the hypothesis that iodine deficiency is associated with an increased risk of gastric cancer...
Polycyclic aromatic hydrocarbon exposure in oesophageal tissue and risk of oesophageal squamous cell carcinoma in north-eastern IranBehnoush Abedi-Ardekani
Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Rm 3018, Bethesda, MD 20892 7232, USA
Gut 59:1178-83. 2010....
Patterns of cancer incidence, mortality, and prevalence across five continents: defining priorities to reduce cancer disparities in different geographic regions of the worldFarin Kamangar
Nutritional Epidemiology and Biostatistics Branches, Division of Cancer Epidemiology and Genetics, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20852-7244, USA
J Clin Oncol 24:2137-50. 2006..For the eight most common cancers, priorities for reducing cancer disparities are discussed...
Determinants of anti-hepatitis A antibody seroprevalence in 2- to 19-year-olds in the USA using NHANES 2007-2008E Velasco-Mondragon
Department of Public Health Analysis, School of Community Health and Policy, Morgan State University, Baltimore, MD 21239, USA
Epidemiol Infect 140:417-25. 2012....
MKK4 status predicts survival after resection of gastric adenocarcinomaSteven C Cunningham
Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, MD 21231-1000, USA
Arch Surg 141:1095-9; discussion 1100. 2006..This finding may provide a useful prognostic tool in patients with gastric adenocarcinoma...
Incidence and age distribution of colorectal cancer in Iran: results of a population-based cancer registryReza Ansari
Digestive Disease Research Center, Tehran University of Medical Sciences, Tehran, Iran
Cancer Lett 240:143-7. 2006..The high proportions of young CRC cases seen in Iran, and probably many neighboring countries, are due to the young age-structure of these countries and relatively low rates of CRC in older individuals...
Chemoprevention of primary liver cancer: a randomized, double-blind trial in Linxian, ChinaChen Xu Qu
Cancer Institute, Chinese Academy of Medical Sciences, Beijing, China
J Natl Cancer Inst 99:1240-7. 2007..We examined the effects of supplementation with four different combinations of vitamins and minerals on primary liver cancer mortality among 29450 initially healthy adults from Linxian, China...
Human papillomavirus in squamous cell carcinoma of esophagus in a high-risk populationMohammad Farhadi
Digestive Disease Research Center, Shariati Hospital, North Kargar Avenue, Tehran 14114, Iran
World J Gastroenterol 11:1200-3. 2005..HPV should be considered as a potential factor contributing to the high incidence of ESCC in Iran and other high-incidence areas of the world...
Re: Helicobacter pylori and interleukin 1 genotyping: an opportunity to identify high-risk individuals for gastric carcinomaFarin Kamangar
J Natl Cancer Inst 95:760; author reply 760-1. 2003
Dietary intake of benzo(a)pyrene and risk of esophageal cancer in north of IranRoya Hakami
Digestive Disease Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
Nutr Cancer 60:216-21. 2008..Polycyclic aromatic hydrocarbons might, along with other risk factors, contribute to the high risk of ESCC in Golestan...
Survival after gastric adenocarcinoma resection: eighteen-year experience at a single institutionSteven C Cunningham
Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21231-1000, USA
J Gastrointest Surg 9:718-25. 2005..Many of the reported differences among Western series may be due to cohort differences, such as stage of disease, extent of resection, tumor type, and tumor location...
Clinical and histological features of nonalcoholic steatohepatitis in Iranian patientsHossein Bahrami
Digestive Diseases Research Center Imam Hospital, Tehran University of Medical Sciences, Iran
BMC Gastroenterol 3:27. 2003..The objective of this study was to assess the clinical and paraclinical features and risk factors for non-alcoholic steatohepatitis (NASH) patients in an Iranian population..
Ecologic study of serum selenium and upper gastrointestinal cancers in IranMehdi Nouarie
Digestive Disease Research Center, Tehran University of Medical Sciences, Iran
World J Gastroenterol 10:2544-6. 2004..CONCLUSION: Our findings suggest that selenium deficiency is not a major contributor to the high incidence of EC seen in northeastern Iran, but it may play a role in the high incidence of GC in Ardabil Province...
Effects of indomethacin on viral replication markers in asymptomatic carriers of hepatitis B: a randomized, placebo-controlled trialHossein Bahrami
Department of Epidemiology, The Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
Am J Gastroenterol 100:856-61. 2005..CONCLUSIONS: We suggest use of indomethacin only in the subgroup of asymptomatic HBsAg carriers who have detectable HBV-DNA or HBeAg in their sera...
Claudin-4, mitogen-activated protein kinase kinase 4, and stratifin are markers of gastric adenocarcinoma precursor lesionsSteven C Cunningham
Department of Oncology, The Johns Hopkins University School of Medicine, Baltimore Maryland 21231, USA
Cancer Epidemiol Biomarkers Prev 15:281-7. 2006..These findings may prove useful in the diagnosis and therapeutic targeting of gastric adenocarcinoma precursor lesions...
