D Thor Johnson

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Functional consequences of mitochondrial proteome heterogeneity
    D Thor Johnson
    Laboratory of Cardiac Energetics, National Heart Lung and Blood Institute, National Institutes of Health, 10 Center Dr, Rm B1D416, Bethesda, MD 20892 1061, USA
    Am J Physiol Cell Physiol 292:C698-707. 2007
  2. pmc Proteomic changes associated with diabetes in the BB-DP rat
    D Thor Johnson
    National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892 1061, USA
    Am J Physiol Endocrinol Metab 296:E422-32. 2009
  3. pmc Use of (32)P to study dynamics of the mitochondrial phosphoproteome
    Angel M Aponte
    Laboratory of Cardiac Energetics and Proteomics Core Facility, National Heart, Lung and Blood Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892 1061, USA
    J Proteome Res 8:2679-95. 2009
  4. pmc 32P labeling of protein phosphorylation and metabolite association in the mitochondria matrix
    Angel M Aponte
    Proteomics Core Facility, National Heart Lung and Blood Institute, DHHS, Bethesda, Maryland, USA
    Methods Enzymol 457:63-80. 2009
  5. ncbi request reprint Tissue heterogeneity of the mammalian mitochondrial proteome
    D Thor Johnson
    Laboratory of Cardiac Energetics, National Heart, Lung, and Blood Institute, National Institutes of Health, 10 Center Dr, Rm B1D416, Bethesda, MD 20892 1061, USA
    Am J Physiol Cell Physiol 292:C689-97. 2007
  6. pmc Mitochondrial matrix phosphoproteome: effect of extra mitochondrial calcium
    Rachel K Hopper
    Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892 1061, USA
    Biochemistry 45:2524-36. 2006
  7. ncbi request reprint A discordance in rosiglitazone mediated insulin sensitization and skeletal muscle mitochondrial content/activity in Type 2 diabetes mellitus
    Ines Pagel-Langenickel
    Cardiology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892 1454, USA
    Am J Physiol Heart Circ Physiol 293:H2659-66. 2007

Collaborators

Detail Information

Publications7

  1. ncbi request reprint Functional consequences of mitochondrial proteome heterogeneity
    D Thor Johnson
    Laboratory of Cardiac Energetics, National Heart Lung and Blood Institute, National Institutes of Health, 10 Center Dr, Rm B1D416, Bethesda, MD 20892 1061, USA
    Am J Physiol Cell Physiol 292:C698-707. 2007
    ..These studies demonstrate the existence of mitochondrial biochemical functions that at present are poorly defined...
  2. pmc Proteomic changes associated with diabetes in the BB-DP rat
    D Thor Johnson
    National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892 1061, USA
    Am J Physiol Endocrinol Metab 296:E422-32. 2009
    ....
  3. pmc Use of (32)P to study dynamics of the mitochondrial phosphoproteome
    Angel M Aponte
    Laboratory of Cardiac Energetics and Proteomics Core Facility, National Heart, Lung and Blood Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892 1061, USA
    J Proteome Res 8:2679-95. 2009
    ..These results demonstrate that a dynamic and extensive mitochondrial matrix phosphoproteome exists in heart and liver...
  4. pmc 32P labeling of protein phosphorylation and metabolite association in the mitochondria matrix
    Angel M Aponte
    Proteomics Core Facility, National Heart Lung and Blood Institute, DHHS, Bethesda, Maryland, USA
    Methods Enzymol 457:63-80. 2009
    ..The use of this, in situ, labeling approach is extremely valuable in confirming protein phosphorylation sites as well as examining the dynamics of these processes under near physiological conditions...
  5. ncbi request reprint Tissue heterogeneity of the mammalian mitochondrial proteome
    D Thor Johnson
    Laboratory of Cardiac Energetics, National Heart, Lung, and Blood Institute, National Institutes of Health, 10 Center Dr, Rm B1D416, Bethesda, MD 20892 1061, USA
    Am J Physiol Cell Physiol 292:C689-97. 2007
    ..These data confirm the notion that mitochondria are tuned by the nucleus for specific functions in different tissues...
  6. pmc Mitochondrial matrix phosphoproteome: effect of extra mitochondrial calcium
    Rachel K Hopper
    Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892 1061, USA
    Biochemistry 45:2524-36. 2006
    ..These data demonstrate the use of a phosphoproteome screen in determining mitochondrial signaling pathways and reveal new pathways for Ca(2+) modification of mitochondrial function at the level of MnSOD...
  7. ncbi request reprint A discordance in rosiglitazone mediated insulin sensitization and skeletal muscle mitochondrial content/activity in Type 2 diabetes mellitus
    Ines Pagel-Langenickel
    Cardiology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892 1454, USA
    Am J Physiol Heart Circ Physiol 293:H2659-66. 2007
    ..It remains to be determined whether longer-term insulin sensitization therapy with rosiglitazone will augment skeletal muscle mitochondrial bioenergetics in those diabetic subjects with relatively preserved basal aerobic capacity...