David A Jett
Affiliation: National Institutes of Health
- Chemical toxins that cause seizuresDavid A Jett
National Institutes of Health, NINDS, Bethesda, MD 20892 9527, USA
Neurotoxicology 33:1473-5. 2012..In this paper, chemicals that cause seizures by a variety of molecular mechanisms and pathways are discussed...
- Neurological aspects of chemical terrorismDavid A Jett
National Institutes of Health, National Institute of Neurological Disorders and Stroke, Office of Technology Development, Bethesda, MD 20892-9527, USA
Ann Neurol 61:9-13. 2007
- Cholinesterase research at the National Institutes of Health, USADavid A Jett
Institute of Neurological Disorders and Stroke, National Institutes of Health, 6001 Executive Boulevard, Bethesda, MD 20892 9535, USA
Chem Biol Interact 175:22-5. 2008..The information was obtained only from published articles or from abstracts available to the public within the NIH CRISP database (http://crisp.cit.nih.gov/)...
- Finding new cures for neurological disorders: a possible fringe benefit of biodefense research?David A Jett
NIH CounterACT Research, National Institutes of Health, National Institute of Neurological Disorders and Stroke, Bethesda, MD 20892, USA
Sci Transl Med 2:23ps12. 2010....
- The CounterACT Research Network: basic mechanisms and practical applicationsDavid A Jett
NIH CounterACT Research, National Institute of Neurological Disorders and Stroke, National Institutes of Health, 6001 Executive Blvd, Bethesda, MD 20892 9527, USA
Proc Am Thorac Soc 7:254-6. 2010..Special consideration is given to research relevant to people who are particularly vulnerable, including the young, the elderly, and individuals with pre-existing medical conditions...
- Neurotoxic pesticides and neurologic effectsDavid A Jett
Office of Translational Research, National Institute of Neurological Disorders and Stroke, National Institutes of Health, 6001 Executive Boulevard, NSC, Room 2177, MSC 9527, Bethesda, MD 20892 9527, USA
Neurol Clin 29:667-77. 2011..Examples of case studies are included to illustrate their toxicity. A discussion of the possible contribution of occupational and other pesticide exposures to neurologic diseases and disorders is also included...
- Increased high-affinity nicotinic receptor-binding in rats exposed to lead during developmentDavid A Jett
Department of Environmental Health Science, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA
Neurotoxicol Teratol 24:805-11. 2002..The data therefore suggest that expression of nicotinic receptors that bind [3H]EB were increased by developmental exposure to Pb. Several possible mechanisms for these effects and the potential toxicological significance are discussed...
- Mechanisms of organophosphate insecticide-induced airway hyperreactivityAllison D Fryer
National Institutes of Health National Institute of Neurological Disorders and Stroke, 6001 Executive Blvd. NSC, Suite 2149, MSC 9535, Bethesda, MD 20892-9835, USA
Am J Physiol Lung Cell Mol Physiol 286:L963-9. 2004..These data demonstrate that organophosphate insecticides can cause airway hyperreactivity in the absence of AChE inhibition by decreasing neuronal M2 receptor function...
- Noncholinesterase mechanisms of chlorpyrifos neurotoxicity: altered phosphorylation of Ca2+/cAMP response element binding protein in cultured neuronsRosemary A Schuh
Department of Environmental Health Science, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland 21205, USA
Toxicol Appl Pharmacol 182:176-85. 2002....