S B Jakowlew

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Effects of transforming growth factor-beta 1 and phorbol ester on PAI-1 and PA genes in human lung cells
    S B Jakowlew
    National Cancer Institute, Biomarkers and Prevention Research Branch, Rockville, Maryland 20850, USA
    Growth Factors 14:177-97. 1997
  2. ncbi request reprint Enhanced tumorigenesis and reduced transforming growth factor-beta type II receptor in lung tumors from mice with reduced gene dosage of transforming growth factor-beta1
    Y Kang
    Medicine Branch, National Cancer Institute, Rockville, Maryland 20850, USA
    Mol Carcinog 29:112-26. 2000
  3. ncbi request reprint Concurrent and distinct transcription and translation of transforming growth factor-beta type I and type II receptors in rodent embryogenesis
    J M Mariano
    National Cancer Institute, Medicine Branch, Department of Cell and Cancer Biology, Rockville, Maryland 20850, USA
    Int J Dev Biol 42:1125-36. 1998
  4. ncbi request reprint Identification of differentially expressed nucleolar TGF-beta1 target (DENTT) in human lung cancer cells that is a new member of the TSPY/SET/NAP-1 superfamily
    L L Ozbun
    Department of Cell and Cancer Biology, National Cancer Institute, Medicine Branch, 9610 Medical Center Drive, Rockville, MD 20850, USA
    Genomics 73:179-93. 2001
  5. ncbi request reprint Coordinate expression of transforming growth factor-beta1 and adrenomedullin in rodent embryogenesis
    L M Montuenga
    Department of Cell and Cancer Biology, National Cancer Institute, Medicine Branch, Rockville, Maryland 20850, USA
    Endocrinology 139:3946-57. 1998
  6. ncbi request reprint Reduction in transforming growth factor-beta type II receptor in mouse lung carcinogenesis
    S B Jakowlew
    Department of Cell and Cancer Biology, Medicine Branch, National Cancer Institute, Rockville, Maryland 20850, USA
    Mol Carcinog 22:46-56. 1998
  7. ncbi request reprint Transforming growth factor-beta1 is a new form of tumor suppressor with true haploid insufficiency
    B Tang
    Laboratory of Cell Regulation and Carcinogenesis formerly Laboratory of Chemoprevention, National Cancer Institute, Bethesda, Maryland 20892 5055, USA
    Nat Med 4:802-7. 1998
  8. ncbi request reprint Transforming growth factor-beta isoforms in the developing chicken intestine and spleen: increase in transforming growth factor-beta 4 with coccidia infection
    S B Jakowlew
    National Cancer Institute, Biomarkers and Prevention Research Branch, Rockville, MD 20850, USA
    Vet Immunol Immunopathol 55:321-39. 1997
  9. ncbi request reprint Heterozygous inactivation of TGF-beta1 increases the susceptibility to chemically induced mouse lung tumorigenesis independently of mutational activation of K-ras
    I M McKenna
    Office of Pollution Prevention and Toxic Substances, US Environmental Protection Agency, Washington, DC 20460, USA
    Toxicol Lett 123:151-8. 2001
  10. ncbi request reprint Identification and characterization of the chicken transforming growth factor-beta 3 promoter
    S B Jakowlew
    Laboratory of Chemoprevention, National Cancer Institute, Bethesda, Maryland 20892
    Mol Endocrinol 6:1285-98. 1992

Collaborators

Detail Information

Publications10

  1. ncbi request reprint Effects of transforming growth factor-beta 1 and phorbol ester on PAI-1 and PA genes in human lung cells
    S B Jakowlew
    National Cancer Institute, Biomarkers and Prevention Research Branch, Rockville, Maryland 20850, USA
    Growth Factors 14:177-97. 1997
    ....
  2. ncbi request reprint Enhanced tumorigenesis and reduced transforming growth factor-beta type II receptor in lung tumors from mice with reduced gene dosage of transforming growth factor-beta1
    Y Kang
    Medicine Branch, National Cancer Institute, Rockville, Maryland 20850, USA
    Mol Carcinog 29:112-26. 2000
    ....
  3. ncbi request reprint Concurrent and distinct transcription and translation of transforming growth factor-beta type I and type II receptors in rodent embryogenesis
    J M Mariano
    National Cancer Institute, Medicine Branch, Department of Cell and Cancer Biology, Rockville, Maryland 20850, USA
    Int J Dev Biol 42:1125-36. 1998
    ..These data show that regulation of TGF-beta1 RI and RII occurs concurrently, but distinctly, in a spatial and temporal manner in rodent embryogenesis which may allow control of signal transduction of TGF-beta during development...
  4. ncbi request reprint Identification of differentially expressed nucleolar TGF-beta1 target (DENTT) in human lung cancer cells that is a new member of the TSPY/SET/NAP-1 superfamily
    L L Ozbun
    Department of Cell and Cancer Biology, National Cancer Institute, Medicine Branch, 9610 Medical Center Drive, Rockville, MD 20850, USA
    Genomics 73:179-93. 2001
    ..TGF-beta1 does not induce DENTT mRNA expression in TGF-beta1 nonresponsive NSCLC cells. Our data suggest that this novel TGF-beta1 target gene has distinct domains for direction to different subnuclear locations...
  5. ncbi request reprint Coordinate expression of transforming growth factor-beta1 and adrenomedullin in rodent embryogenesis
    L M Montuenga
    Department of Cell and Cancer Biology, National Cancer Institute, Medicine Branch, Rockville, Maryland 20850, USA
    Endocrinology 139:3946-57. 1998
    ....
  6. ncbi request reprint Reduction in transforming growth factor-beta type II receptor in mouse lung carcinogenesis
    S B Jakowlew
    Department of Cell and Cancer Biology, Medicine Branch, National Cancer Institute, Rockville, Maryland 20850, USA
    Mol Carcinog 22:46-56. 1998
    ..These data suggest that a decrease in expression of TGF-beta RII may contribute to autonomous cell growth and may play an important role in mouse lung carcinogenesis induced by urethane...
  7. ncbi request reprint Transforming growth factor-beta1 is a new form of tumor suppressor with true haploid insufficiency
    B Tang
    Laboratory of Cell Regulation and Carcinogenesis formerly Laboratory of Chemoprevention, National Cancer Institute, Bethesda, Maryland 20892 5055, USA
    Nat Med 4:802-7. 1998
    ....
  8. ncbi request reprint Transforming growth factor-beta isoforms in the developing chicken intestine and spleen: increase in transforming growth factor-beta 4 with coccidia infection
    S B Jakowlew
    National Cancer Institute, Biomarkers and Prevention Research Branch, Rockville, MD 20850, USA
    Vet Immunol Immunopathol 55:321-39. 1997
    ..The results of this study suggest that TGF-beta may play a role in development of the intestine and spleen in the chicken and that TGF-beta 4 in particular increases after infection of coccidia in the chicken...
  9. ncbi request reprint Heterozygous inactivation of TGF-beta1 increases the susceptibility to chemically induced mouse lung tumorigenesis independently of mutational activation of K-ras
    I M McKenna
    Office of Pollution Prevention and Toxic Substances, US Environmental Protection Agency, Washington, DC 20460, USA
    Toxicol Lett 123:151-8. 2001
    ..It appears that the mechanism of enhanced susceptibility of TGF-beta1+/- mice to urethane-induced lung carcinogenesis does not involve selective development of tumors with K-ras mutations...
  10. ncbi request reprint Identification and characterization of the chicken transforming growth factor-beta 3 promoter
    S B Jakowlew
    Laboratory of Chemoprevention, National Cancer Institute, Bethesda, Maryland 20892
    Mol Endocrinol 6:1285-98. 1992
    ....