G D Jahnke

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Thyroid toxicants: assessing reproductive health effects
    Gloria D Jahnke
    Sciences International Inc, Research Triangle Park, NC 27709, USA
    Environ Health Perspect 112:363-8. 2004
  2. ncbi request reprint Developmental toxicity evaluation of emodin in rats and mice
    Gloria D Jahnke
    Sciences International Inc, Alexandria, Virginia, USA
    Birth Defects Res B Dev Reprod Toxicol 71:89-101. 2004
  3. ncbi request reprint Center for the evaluation of risks to human reproduction--the first five years
    Gloria D Jahnke
    Sciences International, Inc, Research Triangle Park, North Carolina 27709, USA
    Birth Defects Res B Dev Reprod Toxicol 74:1-8. 2005
  4. ncbi request reprint Neurotoxicant-induced elevation of adrenomedullin expression in hippocampus and glia cultures
    G D Jahnke
    Laboratory of Toxicology, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    J Neurosci Res 66:464-74. 2001
  5. ncbi request reprint Maternal and developmental toxicity evaluation of melatonin administered orally to pregnant Sprague-Dawley rats
    G Jahnke
    Reproductive Toxicology Group, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Toxicol Sci 50:271-9. 1999
  6. ncbi request reprint Evaluation of the developmental toxicity of isoeugenol in Sprague-Dawley (CD) rats
    J D George
    Chemistry and Life Sciences, Research Triangle Institute, P O Box 12194, Research Triangle Park, North Carolina 27709 2194, USA
    Toxicol Sci 60:112-20. 2001
  7. ncbi request reprint Evaluation of the developmental toxicity of formamide in Sprague-Dawley (CD) rats
    J D George
    Chemistry and Life Sciences, Research Triangle Institute, Post Office Box 12194, Research Triangle Park, North Carolina 27709 2194, USA
    Toxicol Sci 57:284-91. 2000
  8. ncbi request reprint Developmental toxicity evaluation of 1,2,3,4-butanetetracarboxylic acid in Sprague Dawley (CD) rats
    J D George
    Center for Life Sciences and Toxicology, Chemistry and Life Sciences, Research Triangle Institute, Research Triangle Park, NC 27709 2194, USA
    Reprod Toxicol 15:413-20. 2001
  9. ncbi request reprint Developmental toxicity evaluation of berberine in rats and mice
    Gloria D Jahnke
    Sciences International Inc, Research Triangle Park, North Carolina 27709, USA
    Birth Defects Res B Dev Reprod Toxicol 77:195-206. 2006
  10. ncbi request reprint Prenatal developmental toxicity evaluation of 2',3'-dideoxyinosine (ddI) and 2',3'-didehydro-3'-deoxythymidine (d4T) co-administered to Swiss Albino (CD-1) mice
    Catherine J Price
    Life Sciences and Toxicology, RTI International, Research Triangle Park, North Carolina 27709 2194, USA
    Birth Defects Res B Dev Reprod Toxicol 77:207-15. 2006

Detail Information

Publications15

  1. pmc Thyroid toxicants: assessing reproductive health effects
    Gloria D Jahnke
    Sciences International Inc, Research Triangle Park, NC 27709, USA
    Environ Health Perspect 112:363-8. 2004
    ..Potential screening methods to assess toxicant-induced thyroid dysfunction were outlined, and postnatal bioassays of thyroid-related effects were discussed...
  2. ncbi request reprint Developmental toxicity evaluation of emodin in rats and mice
    Gloria D Jahnke
    Sciences International Inc, Alexandria, Virginia, USA
    Birth Defects Res B Dev Reprod Toxicol 71:89-101. 2004
    ..Emodin, a widely available herbal remedy, was evaluated for potential effects on pregnancy outcome...
  3. ncbi request reprint Center for the evaluation of risks to human reproduction--the first five years
    Gloria D Jahnke
    Sciences International, Inc, Research Triangle Park, North Carolina 27709, USA
    Birth Defects Res B Dev Reprod Toxicol 74:1-8. 2005
    ..At this time, 13 panel reports have been published and 12 NTP-CERHR monographs have been issued. Additionally, CERHR conducted a 2-day workshop on the role of thyroid hormones in reproductive and developmental health...
  4. ncbi request reprint Neurotoxicant-induced elevation of adrenomedullin expression in hippocampus and glia cultures
    G D Jahnke
    Laboratory of Toxicology, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    J Neurosci Res 66:464-74. 2001
    ..These data suggest an interaction between the proinflammatory cytokines and glia response in the regulation of AM in response to injury...
  5. ncbi request reprint Maternal and developmental toxicity evaluation of melatonin administered orally to pregnant Sprague-Dawley rats
    G Jahnke
    Reproductive Toxicology Group, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Toxicol Sci 50:271-9. 1999
    ..Thus, in the definitive study, the maternal toxicity NOAEL and LOAEL were 100 and 200 mg/kg/day, respectively, and the developmental toxicity NOAEL was > or =200 mg/kg/day...
  6. ncbi request reprint Evaluation of the developmental toxicity of isoeugenol in Sprague-Dawley (CD) rats
    J D George
    Chemistry and Life Sciences, Research Triangle Institute, P O Box 12194, Research Triangle Park, North Carolina 27709 2194, USA
    Toxicol Sci 60:112-20. 2001
    ..The developmental toxicity LOAEL was 1000 mg/kg/day based on intrauterine growth retardation and mildly delayed skeletal ossification. The developmental toxicity NOAEL was 500 mg/kg/day...
  7. ncbi request reprint Evaluation of the developmental toxicity of formamide in Sprague-Dawley (CD) rats
    J D George
    Chemistry and Life Sciences, Research Triangle Institute, Post Office Box 12194, Research Triangle Park, North Carolina 27709 2194, USA
    Toxicol Sci 57:284-91. 2000
    ..Similarly, the developmental toxicity NOAEL was 50 mg/kg/day and the LOAEL was 100 mg/kg/day...
  8. ncbi request reprint Developmental toxicity evaluation of 1,2,3,4-butanetetracarboxylic acid in Sprague Dawley (CD) rats
    J D George
    Center for Life Sciences and Toxicology, Chemistry and Life Sciences, Research Triangle Institute, Research Triangle Park, NC 27709 2194, USA
    Reprod Toxicol 15:413-20. 2001
    ..The maternal toxicity NOAEL and LOAEL are 500 and 1000 mg/kg/day, respectively. The developmental toxicity NOAEL is > or = 1000 mg/kg/day, and the LOAEL was not established in this study...
  9. ncbi request reprint Developmental toxicity evaluation of berberine in rats and mice
    Gloria D Jahnke
    Sciences International Inc, Research Triangle Park, North Carolina 27709, USA
    Birth Defects Res B Dev Reprod Toxicol 77:195-206. 2006
    ..Berberine, a plant alkaloid, is found in some herbal teas and health-related products. It is a component of goldenseal, an herbal supplement. Berberine chloride dihydrate (BCD) was evaluated for developmental toxicity in rats and mice...
  10. ncbi request reprint Prenatal developmental toxicity evaluation of 2',3'-dideoxyinosine (ddI) and 2',3'-didehydro-3'-deoxythymidine (d4T) co-administered to Swiss Albino (CD-1) mice
    Catherine J Price
    Life Sciences and Toxicology, RTI International, Research Triangle Park, North Carolina 27709 2194, USA
    Birth Defects Res B Dev Reprod Toxicol 77:207-15. 2006
    ..In pregnant women, antiretroviral drugs improve maternal health and reduce vertical transmission of human immunodeficiency virus to the infant. However, few nonclinical studies have examined the potential for adverse drug interactions...
  11. ncbi request reprint Developmental toxicity evaluation of sodium thioglycolate administered topically to Sprague-Dawley (CD) rats and New Zealand White rabbits
    R W Tyl
    RTI International, Center for Life Sciences and Toxicology, Research Triangle Park, North Carolina 27709 2194, USA
    Birth Defects Res B Dev Reprod Toxicol 68:144-61. 2003
    ..Sodium thioglycolate, which has widespread occupational and consumer exposure to women from cosmetics and hair-care products, was evaluated for developmental toxicity by topical exposure during the embryonic and fetal periods of pregnancy..
  12. ncbi request reprint Evaluation of the developmental toxicity of formamide in New Zealand white rabbits
    Julia D George
    Chemistry and Life Sciences, Center for Life Sciences and Toxicology, Herman Laboratory Building, Research Triangle Institute, P O Box 12194, Research Triangle Park, North Carolina 27709 2194, USA
    Toxicol Sci 69:165-74. 2002
    ..Similarly, the NOAEL for developmental toxicity was 70 mg/kg/day and the LOAEL was 140 mg/kg/day...
  13. ncbi request reprint Postnatal development of rat pups after maternal exposure to diethanolamine
    Catherine J Price
    Life Sciences and Toxicology, RTI International, Research Triangle Park, North Carolina 27709 2194, USA
    Birth Defects Res B Dev Reprod Toxicol 74:243-54. 2005
    ..Teratology 37:503-504, 1988]. The toxicity profile for DEA differs among rodent species. This study investigated DEA-induced postnatal toxicity in a second species...
  14. ncbi request reprint Adrenomedullin expression in the mouse mammary gland: evidence for the mature form in milk
    G D Jahnke
    Laboratory of Toxicology, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    J Mol Endocrinol 19:279-89. 1997
    ..These data suggest a potential role for AM and its receptor in the maintenance of mammary gland homeostasis and suggests a potential role for AM in development of the newborn...
  15. ncbi request reprint Role of thyroid hormones in human and laboratory animal reproductive health
    Neepa Y Choksi
    National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Birth Defects Res B Dev Reprod Toxicol 68:479-91. 2003
    ..Consideration of such information is important in designing, conducting, and interpreting studies to assess the potential effects of thyroid toxicants on reproduction and development...