Research Topics
| J P IoannidisSummaryAffiliation: National Institutes of Health Country: USA Publications
| Collaborators |
Detail Information
Publications
Effect of the statistical significance of results on the time to completion and publication of randomized efficacy trialsJ P Ioannidis
HIV Research Branch, Division of AIDS, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
JAMA 279:281-6. 1998..Medical evidence may be biased over time if completion and publication of randomized efficacy trials are delayed when results are not statistically significant...
Issues in comparisons between meta-analyses and large trialsJ P Ioannidis
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20852, USA
JAMA 279:1089-93. 1998..The extent of concordance between meta-analyses and large trials on the same topic has been investigated with different protocols. Inconsistent conclusions created confusion regarding the validity of these major tools of clinical evidence...
Clinical efficacy of high-dose acyclovir in patients with human immunodeficiency virus infection: a meta-analysis of randomized individual patient dataJ P Ioannidis
HIV Research Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
J Infect Dis 178:349-59. 1998....
Uncontrolled pearls, controlled evidence, meta-analysis and the individual patientJ P Ioannidis
Therapeutics Research Program, DAIDS, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
J Clin Epidemiol 51:709-11. 1998..Concurrent progress in basic sciences revolutionizing our predictive power for disease outcomes will heighten the importance of considering individual heterogeneity...
Statistical issues for HIV surrogate endpoints: point/counterpoint. An NIAID workshopJ M Albert
Division of AIDS, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892 7620, USA
Stat Med 17:2435-62. 1998..These issues will be critical in the proper assessment and use of future therapies for HIV disease...
Comparison of viral load and human leukocyte antigen statistical and neural network predictive models for the rate of HIV-1 disease progression across two cohorts of homosexual menJ P Ioannidis
HIV Research Branch, Division of AIDS, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA
J Acquir Immune Defic Syndr Hum Retrovirol 20:129-36. 1999..The correlation between viral load and HLA markers suggests a possible HLA effect on setting viral load levels...
Predictors and impact of losses to follow-up in an HIV-1 perinatal transmission cohort in MalawiJ P Ioannidis
HIV Research Branch, Division of AIDS, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, USA
Int J Epidemiol 28:769-75. 1999..A better understanding of the characteristics and the impact of women and children lost to follow-up is needed...
Effect of chemokine receptor gene polymorphisms on the response to potent antiretroviral therapyT R O'Brien
Viral Epidemiology Branch, National Cancer Institute, Bethesda, Maryland, USA
AIDS 14:821-6. 2000..In comparison with subjects with other genotypes, the prognosis for HIV-1-infected CCR5-delta32 heterozygotes is more favorable and that for CCR5 promoter allele 59029A homozygotes is less favorable...
