Research Topics
Genomes and Genes
Species | P D InskipSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
Cellular-telephone use and brain tumorsP D Inskip
Epidemiology and Biostatistics Program, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
N Engl J Med 344:79-86. 2001..If such a risk does exist, the matter would be of considerable public health importance, given the rapid increase worldwide in the use of these devices...- Trends in the incidence of ocular melanoma in the United States, 1974-1998Peter D Inskip
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892 7238, USA
Cancer Causes Control 14:251-7. 2003..A recent report noted a fourfold risk of ocular melanoma associated with employment in occupations involving use of cellular telephones... - New malignancies following childhood cancer in the United States, 1973-2002Peter D Inskip
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, DHHS, Bethesda, MD, USA
Int J Cancer 121:2233-40. 2007.... - Multiple primary tumors involving cancer of the brain and central nervous system as the first or subsequent cancerPeter D Inskip
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
Cancer 98:562-70. 2003..This study was undertaken to determine whether cancer of the brain and central nervous system (CNS) occurs together with other types of cancer more often or less often than would be expected due to chance... - Laterality of brain tumorsPeter D Inskip
Epidemiology and Biostatistics Program, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Natioanl Institutes of Health, Bethesda, MD 20892, USA
Neuroepidemiology 22:130-8. 2003..Associations between tumor laterality and symptoms may influence the probability or timing of diagnosis, possibly differentially by marital status... - Thyroid cancer after radiotherapy for childhood cancerP D Inskip
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA
Med Pediatr Oncol 36:568-73. 2001.... 
Radiation dose and breast cancer risk in the childhood cancer survivor studyPeter D Inskip
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7238, USA
J Clin Oncol 27:3901-7. 2009..The purpose of this study was to quantify the risk of breast cancer in relation to radiation dose and chemotherapy among survivors of childhood cancer...- Brain cancer incidence trends in relation to cellular telephone use in the United StatesPeter D Inskip
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Executive Plaza South, Room 7052, Bethesda, MD 20892, USA
Neuro Oncol 12:1147-51. 2010..Overall, these incidence data do not provide support to the view that cellular phone use causes brain cancer... - Season of birth and risk of brain tumors in adultsA V Brenner
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, 6120 Executive Blvd, Bethesda, MD 20892 7238, USA
Neurology 63:276-81. 2004..Recent studies demonstrated an excess of winter births in children with brain tumors and in adults with various neurologic or psychiatric diseases relative to the general population... - Lead exposure, polymorphisms in genes related to oxidative stress, and risk of adult brain tumorsParveen Bhatti
Department of Health ad Human Services, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland, USA
Cancer Epidemiol Biomarkers Prev 18:1841-8. 2009..Although the results of this study provide some evidence that lead may cause glioblastoma multiforme and meningioma through mechanisms related to oxidative damage, the results must be confirmed in other populations... - Cancer in first-degree relatives and risk of glioma in adultsDeirdre A Hill
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892-7238, USA
Cancer Epidemiol Biomarkers Prev 12:1443-8. 2003..Shared environmental or genetic factors in families may influence glioma risk. Our findings suggest that individuals with a family history of specific cancers other than glioma may have an increased glioma risk... - Occupation and the risk of adult glioma in the United StatesA J De Roos
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
Cancer Causes Control 14:139-50. 2003..CONCLUSIONS: This is our first analysis of occupation and will guide future exposure-specific assessments... - Sociodemographic indicators and risk of brain tumoursPeter D Inskip
Epidemiology and Biostatistics Program, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
Int J Epidemiol 32:225-33. 2003..There is less opportunity for such influences to operate for the rapidly progressing, high-grade gliomas than for more slowly growing tumours... - Handedness and risk of brain tumors in adultsPeter D Inskip
Epidemiology and Biostatistics Program, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892, USA
Cancer Epidemiol Biomarkers Prev 12:223-5. 2003..These findings require confirmation but raise the possibility that early neurodevelopmental events or genetic factors related to handedness also influence the risk of glioma among adults... - Single-nucleotide polymorphisms in selected cytokine genes and risk of adult gliomaA V Brenner
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD 20892 7238, USA
Carcinogenesis 28:2543-7. 2007..07 and 0.22, respectively). Our results underscore the importance of pooled analyses in genetic association studies and suggest that SNPs in cytokine genes may influence susceptibility to glioma... - Thyroid cancer in childhood cancer survivors: a detailed evaluation of radiation dose response and its modifiersCécile M Ronckers
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, Maryland
Radiat Res 166:618-28. 2006..In summary, we applied models derived from radiobiology to describe the radiation dose-response curve for thyroid cancer in an epidemiological study and found convincing evidence for a downturn in risk at high doses... - Mobile phone use and glioma risk: comparison of epidemiological study results with incidence trends in the United StatesM P Little
Radiation Epidemiology Branch, National Cancer Institute, Rockville, MD 20852 7238, USA
BMJ 344:e1147. 2012.... - Reproductive and hormonal factors and risk of brain tumors in adult femalesElizabeth E Hatch
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, MD, USA
Int J Cancer 114:797-805. 2005..The findings suggest that hormonal exposures early in life may be associated with risk of glioma, but the evidence is inconsistent and does not point clearly to a specific causal or protective hypothesis... - Glioma risk in relation to serum levels of insulin-like growth factorsStefan Lonn
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Room 7053, 6120 Executive Boulevard, Bethesda, MD 20892 7238, USA
Cancer Epidemiol Biomarkers Prev 16:844-6. 2007..3; 95% confidence interval, 0.1-0.7). The results encourage future research on IGFs in relation to brain tumors in larger studies... - Lead, genetic susceptibility, and risk of adult brain tumorsPreetha Rajaraman
Division of Cancer Epidemiology Branch, National Cancer Institute, NIH, Department of Health and Human Services, 6120 Executive Boulevard, EPS Room 7085, Bethesda, MD 20892 7238, USA
Cancer Epidemiol Biomarkers Prev 15:2514-20. 2006..The ALAD G177C polymorphism affects the toxicokinetics of lead and may confer genetic susceptibility to adverse effects of lead exposure... - Personal hair dye use and risks of glioma, meningioma, and acoustic neuroma among adultsElizabeth C Bluhm
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
Am J Epidemiol 165:63-71. 2007..However, prolonged use of dark-colored permanent dyes warrants further investigation given the high prevalence of hair dyeing... - Common variation in genes related to innate immunity and risk of adult gliomaPreetha Rajaraman
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20852, USA
Cancer Epidemiol Biomarkers Prev 18:1651-8. 2009..We have identified a promising set of innate immunity-related genetic regions for further investigation... - Seasonality in birth weight in Israel: new evidence suggests several global patterns and different etiologiesGabriel Chodick
Medical Informatics Department, Maccabi Healthcare Services, Tel Aviv, Israel
Ann Epidemiol 17:440-6. 2007..To investigate the effect of season on birth weight and whether it is expressed also in fluctuations of proportions of extreme birth weights... - Sex disparities in cancer incidence by period and ageMichael B Cook
National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, MD 20852 7234, USA
Cancer Epidemiol Biomarkers Prev 18:1174-82. 2009..Cancer epidemiology articles often point out that cancer rates tend to be higher among males than females yet rarely is this theme the subject of investigation... - Occupational exposure to magnetic fields and the risk of brain tumorsJoseph B Coble
National Cancer Institute, Rockville, MD 20892, USA
Neuro Oncol 11:242-9. 2009..Occupational exposure to MFs assessed using job modules was not associated with an increase in the risk for glioma, glioblastoma, or meningioma among the subjects evaluated in this study... - Oxidative response gene polymorphisms and risk of adult brain tumorsPreetha Rajaraman
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892 7238, USA
Neuro Oncol 10:709-15. 2008..6; 95% CI, 0.3-1.0). These relationships persisted when major groups of disease controls were excluded from the analysis. Our results suggest that common variants in the SOD2, SOD3, and CAT genes may influence brain tumor risk... - Polymorphisms in apoptosis and cell cycle control genes and risk of brain tumors in adultsPreetha Rajaraman
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, EPS Room 7085, 6120 Executive Boulevard, Bethesda, MD 20892 7238, USA
Cancer Epidemiol Biomarkers Prev 16:1655-61. 2007..Our results suggest that common variants in the CASP8, CCND1, CCNH, and MDM2 genes may influence brain tumor risk. Future research in this area should include more detailed coverage of genes in the apoptosis/cell cycle control pathways... - Cause-specific mortality and second cancer incidence after non-Hodgkin lymphoma: a report from the Childhood Cancer Survivor StudyElizabeth C Bluhm
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, MSC 7238, Rockville, MD 20892 7238, USA
Blood 111:4014-21. 2008..1), mediastinal NHL disease (RR = 5.2), and breast irradiation (RR = 4.3). Survivors of childhood NHL, particularly those treated with chest RT, are at continued increased risk of early mortality and solid tumor SMNs... 
Occupational exposure to pesticides and risk of adult brain tumorsClaudine M Samanic
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20852, USA
Am J Epidemiol 167:976-85. 2008..01). There was no association between meningioma and herbicide or insecticide exposure among men. These findings highlight the need to go beyond job title to elucidate potential carcinogenic exposures within different occupations...- Genetic polymorphisms in GSTM1, -P1, -T1, and CYP2E1 and the risk of adult brain tumorsAnneclaire J De Roos
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892 7240, USA
Cancer Epidemiol Biomarkers Prev 12:14-22. 2003..5; 95% CL, 1.0, 2.3). These findings may provide clues to both genetic and environmental determinants of brain tumors... - The chornobyl accident: estimation of radiation doses received by the Baltic and Ukrainian cleanup workersAndre Bouville
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, DHHS, Bethesda, Maryland 20892, USA
Radiat Res 166:158-67. 2006..After an overview of the sources of exposure and of the radiation doses received by the cleanup workers, a description of the efforts made to estimate individual doses in the Baltic and Ukrainian studies is presented... - History of allergies and autoimmune diseases and risk of brain tumors in adultsAlina V Brenner
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 7362, USA
Int J Cancer 99:252-9. 2002..The basis of the associations is not clear, but they might imply a role of immunologic factors in the development of brain tumors. Published 2002 Wiley-Liss, Inc... - Meningioma and schwannoma risk in adults in relation to family history of cancerDeirdre A Hill
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
Neuro Oncol 6:274-80. 2004..Inheritance of predisposing genes, shared environmental factors, or both within families with a history of benign brain tumors, melanoma, or possibly breast cancer may be related to altered meningioma risk... - Sex disparities in colorectal cancer incidence by anatomic subsite, race and ageGwen Murphy
Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD
Int J Cancer 128:1668-75. 2011..These findings may partially reflect differences in screening experiences and access to medical care but also suggest that etiologic factors may be playing a role... - Self-reported electrical appliance use and risk of adult brain tumorsRuth A Kleinerman
Radiation Epidemiology Branch, National Cancer Institute, National Institutes of Health, 6120 Executive Boulevard, EPS 7044, Rockville, MD 20852 7238, USA
Am J Epidemiol 161:136-46. 2005..Overall, results indicate that extremely low frequency electromagnetic fields from commonly used household appliances are unlikely to increase the risk of brain tumors... - Risk of meningioma and common variation in genes related to innate immunityPreetha Rajaraman
Division of Cancer Epidemiology and Genetics, Neuro Oncology Branch, National Cancer Institute, NIH, Department of Health and Human Services, 6120 Executive Boulevard, EPS Room 7058, Bethesda, MD 20892 7238, USA
Cancer Epidemiol Biomarkers Prev 19:1356-61. 2010..The etiology of meningioma, the second most common type of adult brain tumor in the United States, is largely unknown. Prior studies indicate that history of immune-related conditions may affect the risk of meningioma... - The risk of developing second cancers among survivors of childhood soft tissue sarcomaRandi J Cohen
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
Cancer 103:2391-6. 2005..CONCLUSIONS: The risk of second malignancies was increased for all histologic types of childhood STS and was particularly high among patients who received combined modality therapy... - Primary thyroid cancer after a first tumour in childhood (the Childhood Cancer Survivor Study): a nested case-control studyAlice J Sigurdson
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7238, USA
Lancet 365:2014-23. 2005..We aimed to quantify the long-term risk of thyroid cancer after radiotherapy and chemotherapy... - Delta-aminolevulinic acid dehydratase polymorphism and risk of brain tumors in adultsPreetha Rajaraman
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
Environ Health Perspect 113:1209-11. 2005..2; 95% CI, 0.7-2.2). No increased risk associated with the ALAD2 variant was observed for glioma or acoustic neuroma. These findings suggest that the ALAD2 allele may increase genetic susceptibility to meningioma... - Occupation and risk of meningioma and acoustic neuroma in the United StatesPreetha Rajaraman
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892 7238, USA
Am J Ind Med 45:395-407. 2004..Workplace exposures may be related to the development of brain tumors. In this case-control study, we examine occupation as a risk factor for meningioma and acoustic neuroma... - DNA repair gene polymorphisms and risk of adult meningioma, glioma, and acoustic neuromaPreetha Rajaraman
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, DHHS, Bethesda, MD 20892 7238, USA
Neuro Oncol 12:37-48. 2010..03). Decreased glioma risk was observed with the XRCC1 rs1799782 variant (P(trend) .04). Our results suggest that common DNA repair variants may affect the risk of adult brain tumors, especially meningioma... - Polio vaccination and risk of brain tumors in adults: no apparent associationAlina V Brenner
Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892-7362, USA
Cancer Epidemiol Biomarkers Prev 12:177-8. 2003 - Genetic variation in insulin-like growth factors and brain tumor riskStefan Lonn
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7238, USA
Neuro Oncol 10:553-9. 2008..Overall, our results do not provide strong evidence of associations of brain tumor risk with IGF polymorphic variants but identify several associations for glioma that warrant further examination in other, larger studies... - Obesity in adult survivors of childhood acute lymphoblastic leukemia: a report from the Childhood Cancer Survivor StudyKevin C Oeffinger
Department of Family Practice and Community Medicine, University of Texas Southwestern Medical Center at Dallas, 753900 9067, USA
J Clin Oncol 21:1359-65. 2003..To determine whether adult survivors (>or= 18 years of age) of childhood acute lymphoblastic leukemia (ALL) are at increased risk for obesity and to assess patient and treatment variables that influence risk... - Comparison of documented and recalled histories of exposure to diagnostic x-rays in case-control studies of thyroid cancerAmy Berrington de Gonzalez
Cancer Research UK Epidemiology Unit, University of Oxford, Oxford, United Kingdom
Am J Epidemiol 157:652-63. 2003..However, in the present data, reporting errors by cases and controls seemed to be largely nondifferential... - Clinical and epidemiologic characteristics of first primary tumors of the central nervous system and related organs among atomic bomb survivors in Hiroshima and Nagasaki, 1958-1995Shuji Yonehara
Department of Pathology and Research Laboratory, Welfare Association Onomichi General Hospital, Japan
Cancer 101:1644-54. 2004..The secular rise in incidence of all clinically diagnosed CNS and pituitary gland tumors is most likely to be attributable to the increased use of new imaging techniques... - Suicide after childhood cancerRegan A Howard
J Clin Oncol 25:731; author reply 733-4. 2007 - Cancer risk among Chernobyl cleanup workers in Estonia and Latvia, 1986-1998Mati Rahu
Department of Epidemiology and Biostatistics, National Institute for Health Development, Tallinn, Estonia
Int J Cancer 119:162-8. 2006..Further follow-up of Chernobyl cleanup workers is warranted to clarify the possible health effects of radiation exposure... - New primary neoplasms of the central nervous system in survivors of childhood cancer: a report from the Childhood Cancer Survivor StudyJoseph P Neglia
Department of Pediatrics, University of Minnesota School of Medicine, Minneapolis, MN, USA
J Natl Cancer Inst 98:1528-37. 2006..However, the details of the dose-response relationships, the expression of excess risk over time, and the modifying effects of other host and treatment factors have not been well defined... - Variation in genes relevant to aromatic hydrocarbon metabolism and the risk of adult brain tumorsAnneclaire J De Roos
Fred Hutchinson Cancer Research Center and University of Washington Department of Epidemiology, Seattle, WA 98109, USA
Neuro Oncol 8:145-55. 2006..The association with the GSTM3 *B allele, while intriguing, requires replication, and additional research is needed to clarify the function of the GSTM3 alleles studied here... - Mobile phone use and acoustic neuromasRobert E Tarone
Epidemiology 16:414; author reply 417-8. 2005 - Breast cancer after childhood cancer: a report from the Childhood Cancer Survivor StudyLisa B Kenney
Children s Hospital and Dana Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115, USA
Ann Intern Med 141:590-7. 2004..Survivors of childhood cancer are at risk for secondary breast cancer. Other than previous chest radiation therapy, risk factors for secondary breast cancer have not been established... - Characteristics of childhood cancer survivors predicted their successful tracingAnn C Mertens
Department of Pediatrics Epidemiology and Clinical Research, University of Minnesota Medical School and Cancer Center, 420 Delaware Street, SE, Minneapolis, MN 55455, USA
J Clin Epidemiol 57:933-44. 2004..We evaluated the characteristics of those requiring tracing and factors that influenced tracing success... - Long-term neurologic and neurosensory sequelae in adult survivors of a childhood brain tumor: childhood cancer survivor studyRoger J Packer
Department of Neurology, Center for Neuroscience and Behavioral Medicine, Children s National Medical Center, Washington, DC, USA
J Clin Oncol 21:3255-61. 2003..To describe the neurologic and neurosensory deficits in children with brain tumors (BTs), compare incidence of these deficits with that of a sibling control group, and evaluate the factors associated with the development of these deficits... - Issues of diagnostic review in brain tumor studies: from the Brain Tumor Epidemiology ConsortiumFaith G Davis
Division of Epidemiology Biostatistics, School of Public Health, University of Illinois at Chicago, Chicago, IL 60612, USA
Cancer Epidemiol Biomarkers Prev 17:484-9. 2008..It is essential that epidemiologists and neuropathologists collaborate to develop appropriate study designs and protocols for specific hypothesis and populations...