Grace Ibay

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Identification of tag single-nucleotide polymorphisms in regions with varying linkage disequilibrium
    Priya Duggal
    Inherited Disease Research Branch, NHGRI NIH, Baltimore, MD, USA
    BMC Genet 6:S73. 2005
  2. pmc Candidate high myopia loci on chromosomes 18p and 12q do not play a major role in susceptibility to common myopia
    Grace Ibay
    Inherited Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, 333 Cassell Dr, Suite 2000, Baltimore, MD 21224, USA
    BMC Med Genet 5:20. 2004
  3. pmc Genomewide linkage scans for ocular refraction and meta-analysis of four populations in the Myopia Family Study
    Robert Wojciechowski
    Inherited Disease Research Branch, National Human Genome Research Institute, Baltimore, Maryland 21231, USA
    Invest Ophthalmol Vis Sci 50:2024-32. 2009
  4. pmc Dissecting the genetic heterogeneity of myopia susceptibility in an Ashkenazi Jewish population using ordered subset analysis
    Claire L Simpson
    1nherited Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Baltimore, MD 21224, USA
    Mol Vis 17:1641-51. 2011
  5. pmc GeneLink: a database to facilitate genetic studies of complex traits
    Elizabeth M Gillanders
    Cancer Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892 8000, USA
    BMC Genomics 5:81. 2004
  6. pmc Importance sampling method of correction for multiple testing in affected sib-pair linkage analysis
    Alison P Klein
    Inherited Disease Research Branch, NHGRI, NIH, Baltimore, Maryland, USA
    BMC Genet 4:S73. 2003
  7. pmc Genomewide scan in Ashkenazi Jewish families demonstrates evidence of linkage of ocular refraction to a QTL on chromosome 1p36
    Robert Wojciechowski
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    Hum Genet 119:389-99. 2006
  8. ncbi request reprint Genome-wide scan for myopia in the Old Order Amish
    Dwight Stambolian
    Department of Ophthalmology, Stellar Chance Laboratories Rm 313, University of Pennsylvania, 422 Curie Boulevard, Philadelphia, PA 19104, USA
    Am J Ophthalmol 140:469-76. 2005
  9. ncbi request reprint Genome-wide scan of additional Jewish families confirms linkage of a myopia susceptibility locus to chromosome 22q12
    Dwight Stambolian
    Department of Ophthalmology, University of Pennsylvania, Philadelphia, PA 19104, USA
    Mol Vis 12:1499-505. 2006
  10. pmc Genomewide scan of ocular refraction in African-American families shows significant linkage to chromosome 7p15
    Elise Ciner
    The Eye Institute of the Pennsylvania College of Optometry, Philadelphia, Pennsylvania, USA
    Genet Epidemiol 32:454-63. 2008

Collaborators

Detail Information

Publications11

  1. pmc Identification of tag single-nucleotide polymorphisms in regions with varying linkage disequilibrium
    Priya Duggal
    Inherited Disease Research Branch, NHGRI NIH, Baltimore, MD, USA
    BMC Genet 6:S73. 2005
    ..In addition, we compared the selected SNPs in a multipoint linkage analysis for one region with strong LD. As the number of selected SNPs increased, the LOD score, mean information content, and type I error also increased...
  2. pmc Candidate high myopia loci on chromosomes 18p and 12q do not play a major role in susceptibility to common myopia
    Grace Ibay
    Inherited Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, 333 Cassell Dr, Suite 2000, Baltimore, MD 21224, USA
    BMC Med Genet 5:20. 2004
    ..We hypothesized that these high myopia loci might exhibit allelic heterogeneity and be responsible for moderate /mild or common myopia...
  3. pmc Genomewide linkage scans for ocular refraction and meta-analysis of four populations in the Myopia Family Study
    Robert Wojciechowski
    Inherited Disease Research Branch, National Human Genome Research Institute, Baltimore, Maryland 21231, USA
    Invest Ophthalmol Vis Sci 50:2024-32. 2009
    ..We also performed a meta-analysis by combining these results with our previous linkage results from Ashkenazi Jewish (ASHK) and African American (AFRAM) families...
  4. pmc Dissecting the genetic heterogeneity of myopia susceptibility in an Ashkenazi Jewish population using ordered subset analysis
    Claire L Simpson
    1nherited Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Baltimore, MD 21224, USA
    Mol Vis 17:1641-51. 2011
    ..Genetic studies have pointed to a strong inherited component, but although many candidate regions have been implicated, few genes have been positively identified...
  5. pmc GeneLink: a database to facilitate genetic studies of complex traits
    Elizabeth M Gillanders
    Cancer Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892 8000, USA
    BMC Genomics 5:81. 2004
    ..To minimize the difficulties inherent in complex trait studies, we have developed GeneLink, a Web-accessible, password-protected Sybase database...
  6. pmc Importance sampling method of correction for multiple testing in affected sib-pair linkage analysis
    Alison P Klein
    Inherited Disease Research Branch, NHGRI, NIH, Baltimore, Maryland, USA
    BMC Genet 4:S73. 2003
    ..The ability of these methods to detect trait loci was also low. However, this may be partially due to a limitation inherent in our binary trait definitions...
  7. pmc Genomewide scan in Ashkenazi Jewish families demonstrates evidence of linkage of ocular refraction to a QTL on chromosome 1p36
    Robert Wojciechowski
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    Hum Genet 119:389-99. 2006
    ..Conclusion: We found genomewide significant evidence for linkage of refractive error to a novel QTL on chromosome 1p36 in an Ashkenazi Jewish population...
  8. ncbi request reprint Genome-wide scan for myopia in the Old Order Amish
    Dwight Stambolian
    Department of Ophthalmology, Stellar Chance Laboratories Rm 313, University of Pennsylvania, 422 Curie Boulevard, Philadelphia, PA 19104, USA
    Am J Ophthalmol 140:469-76. 2005
    ..To identify myopia susceptibility genes influencing common myopia in 34 Old Order Amish families, a genetically well-defined founder population...
  9. ncbi request reprint Genome-wide scan of additional Jewish families confirms linkage of a myopia susceptibility locus to chromosome 22q12
    Dwight Stambolian
    Department of Ophthalmology, University of Pennsylvania, Philadelphia, PA 19104, USA
    Mol Vis 12:1499-505. 2006
    ..A genome-wide scan was previously reported for myopia in Ashkenazi Jews. In order to confirm the previous linkage peaks, a collection of DNA samples from 19 new Ashkenazi Jewish families were tested for linkage in a genome wide scan...
  10. pmc Genomewide scan of ocular refraction in African-American families shows significant linkage to chromosome 7p15
    Elise Ciner
    The Eye Institute of the Pennsylvania College of Optometry, Philadelphia, Pennsylvania, USA
    Genet Epidemiol 32:454-63. 2008
    ..The genomic region under our linkage peak spans approximately 17 Mb and contains approximately 170 genes. Further refinement of this region will be pursued in future studies...
  11. pmc Genomewide linkage scan for myopia susceptibility loci among Ashkenazi Jewish families shows evidence of linkage on chromosome 22q12
    Dwight Stambolian
    Department of Ophthalmology, University of Pennsylvania, Philadelphia, PA 19104, USA
    Am J Hum Genet 75:448-59. 2004
    ..Identification of a susceptibility locus in this region may eventually lead to a better understanding of gene-environment interactions in the causation of this complex trait...