S E Hyman

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint National Institute of Mental Health goals for behavioral science
    S E Hyman
    National Institute of Mental Health, Bethesda, Maryland 20892, USA
    Exp Clin Psychopharmacol 8:271-2. 2000
  2. ncbi request reprint Addiction and the brain: the neurobiology of compulsion and its persistence
    S E Hyman
    National Institute of Mental Health, 6001 Executive Boulevard, Bethesda, Maryland 20892 9669, USA
    Nat Rev Neurosci 2:695-703. 2001
  3. ncbi request reprint 5-HT3 receptor activation is required for induction of striatal c-Fos and phosphorylation of ATF-1 by amphetamine
    L M Genova
    Program in Neuroscience, Harvard University, Boston, Massachusetts 02115, USA
    Synapse 30:71-8. 1998
  4. pmc Inhibiting activator protein-1 activity alters cocaine-induced gene expression and potentiates sensitization
    R F Paletzki
    Laboratory of Molecular Pathophysiology, National Institute of Neurological Disorders and Stroke, NIH, Building 36, Room 4C 24, Bethesda, MD 20892, USA
    Neuroscience 152:1040-53. 2008
  5. ncbi request reprint Dopamine and glutamate induce distinct striatal splice forms of Ania-6, an RNA polymerase II-associated cyclin
    J D Berke
    Molecular Plasticity Section, National Institute of Neurological Disorders and Stroke, Bethesda, MD 20892, USA
    Neuron 32:277-87. 2001
  6. pmc The genetics of mental illness: implications for practice
    S E Hyman
    National Institute of Mental Health, Bethesda, MD 20892 9669, USA
    Bull World Health Organ 78:455-63. 2000
  7. ncbi request reprint A complex program of striatal gene expression induced by dopaminergic stimulation
    J D Berke
    Molecular Plasticity Section, National Institute of Neurological Disorders and Stroke, Bethesda, Maryland 20892, USA
    J Neurosci 18:5301-10. 1998

Detail Information

Publications7

  1. ncbi request reprint National Institute of Mental Health goals for behavioral science
    S E Hyman
    National Institute of Mental Health, Bethesda, Maryland 20892, USA
    Exp Clin Psychopharmacol 8:271-2. 2000
    ....
  2. ncbi request reprint Addiction and the brain: the neurobiology of compulsion and its persistence
    S E Hyman
    National Institute of Mental Health, 6001 Executive Boulevard, Bethesda, Maryland 20892 9669, USA
    Nat Rev Neurosci 2:695-703. 2001
    ..Here we review evidence for the possibility that compulsion and its persistence are based on a pathological usurpation of molecular mechanisms that are normally involved in memory...
  3. ncbi request reprint 5-HT3 receptor activation is required for induction of striatal c-Fos and phosphorylation of ATF-1 by amphetamine
    L M Genova
    Program in Neuroscience, Harvard University, Boston, Massachusetts 02115, USA
    Synapse 30:71-8. 1998
    ..These results suggest that 5-HT3 receptor activation may be required for amphetamine-induced expression of ATF-1-regulated target genes in the striatum, which may include c-Fos...
  4. pmc Inhibiting activator protein-1 activity alters cocaine-induced gene expression and potentiates sensitization
    R F Paletzki
    Laboratory of Molecular Pathophysiology, National Institute of Neurological Disorders and Stroke, NIH, Building 36, Room 4C 24, Bethesda, MD 20892, USA
    Neuroscience 152:1040-53. 2008
    ..The chromosomal location of these 84 genes was compared with human genome scans of addiction to identify potential genes in humans that are involved in addiction...
  5. ncbi request reprint Dopamine and glutamate induce distinct striatal splice forms of Ania-6, an RNA polymerase II-associated cyclin
    J D Berke
    Molecular Plasticity Section, National Institute of Neurological Disorders and Stroke, Bethesda, MD 20892, USA
    Neuron 32:277-87. 2001
    ..Distinct types of neuronal stimulation may therefore differentially modulate nuclear RNA processing, through altered transcription and splicing of ania-6...
  6. pmc The genetics of mental illness: implications for practice
    S E Hyman
    National Institute of Mental Health, Bethesda, MD 20892 9669, USA
    Bull World Health Organ 78:455-63. 2000
    ..Genetics should yield new therapies aimed not just at symptoms but also at pathogenic processes, thus permitting the targeting of specific therapies to individual patients...
  7. ncbi request reprint A complex program of striatal gene expression induced by dopaminergic stimulation
    J D Berke
    Molecular Plasticity Section, National Institute of Neurological Disorders and Stroke, Bethesda, Maryland 20892, USA
    J Neurosci 18:5301-10. 1998
    ..Thus we have identified novel components of a complex, coordinated genetic program that is induced in striatal cells in response to various dopaminergic manipulations...