Keith M Hull

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi Monocytic fasciitis: a newly recognized clinical feature of tumor necrosis factor receptor dysfunction
    Keith M Hull
    National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH, Bethesda, Maryland 20892, USA
    Arthritis Rheum 46:2189-94. 2002
  2. ncbi The TNF receptor-associated periodic syndrome (TRAPS): emerging concepts of an autoinflammatory disorder
    Keith M Hull
    Office of the Clinical Director, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Medicine (Baltimore) 81:349-68. 2002
  3. ncbi The expanding spectrum of systemic autoinflammatory disorders and their rheumatic manifestations
    Keith M Hull
    Office of the Clinical Director, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Curr Opin Rheumatol 15:61-9. 2003
  4. ncbi Efficacy of etanercept in the tumor necrosis factor receptor-associated periodic syndrome: a prospective, open-label, dose-escalation study
    Ariel C Bulua
    National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH, Bethesda, MD 20892, USA
    Arthritis Rheum 64:908-13. 2012
  5. ncbi Pyrin binds the PSTPIP1/CD2BP1 protein, defining familial Mediterranean fever and PAPA syndrome as disorders in the same pathway
    Nitza G Shoham
    Genetics and Genomics Branch and Office of the Clinical Director, National Institute of Arthritis and Musculoskeletal and Skin Diseases, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 100:13501-6. 2003
  6. ncbi Abnormal disulfide-linked oligomerization results in ER retention and altered signaling by TNFR1 mutants in TNFR1-associated periodic fever syndrome (TRAPS)
    Adrian A Lobito
    Immunoregulation Unit, Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda MD 20892, USA
    Blood 108:1320-7. 2006
  7. ncbi Hereditary periodic fever
    Keith M Hull
    N Engl J Med 346:1415-6; author reply 1415-6. 2002

Collaborators

Detail Information

Publications7

  1. ncbi Monocytic fasciitis: a newly recognized clinical feature of tumor necrosis factor receptor dysfunction
    Keith M Hull
    National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH, Bethesda, Maryland 20892, USA
    Arthritis Rheum 46:2189-94. 2002
    ..These results suggest that the myalgia experienced by individuals with TRAPS is due to a monocytic fasciitis and not to myositis...
  2. ncbi The TNF receptor-associated periodic syndrome (TRAPS): emerging concepts of an autoinflammatory disorder
    Keith M Hull
    Office of the Clinical Director, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Medicine (Baltimore) 81:349-68. 2002
    ..Our laboratories are currently undertaking both clinical and basic research studies to define the role of these mutations in more common inflammatory diseases...
  3. ncbi The expanding spectrum of systemic autoinflammatory disorders and their rheumatic manifestations
    Keith M Hull
    Office of the Clinical Director, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Curr Opin Rheumatol 15:61-9. 2003
    ..Lastly, the authors discuss the broadening genetic and clinical spectrum of TRAPS, an autoinflammatory syndrome resulting from mutations in the 55-kDa receptor for tumor necrosis factor...
  4. ncbi Efficacy of etanercept in the tumor necrosis factor receptor-associated periodic syndrome: a prospective, open-label, dose-escalation study
    Ariel C Bulua
    National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH, Bethesda, MD 20892, USA
    Arthritis Rheum 64:908-13. 2012
    ..To investigate the efficacy of etanercept in improving the symptoms and underlying inflammation in patients with tumor necrosis factor receptor-associated periodic syndrome (TRAPS)...
  5. ncbi Pyrin binds the PSTPIP1/CD2BP1 protein, defining familial Mediterranean fever and PAPA syndrome as disorders in the same pathway
    Nitza G Shoham
    Genetics and Genomics Branch and Office of the Clinical Director, National Institute of Arthritis and Musculoskeletal and Skin Diseases, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 100:13501-6. 2003
    ....
  6. ncbi Abnormal disulfide-linked oligomerization results in ER retention and altered signaling by TNFR1 mutants in TNFR1-associated periodic fever syndrome (TRAPS)
    Adrian A Lobito
    Immunoregulation Unit, Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda MD 20892, USA
    Blood 108:1320-7. 2006
    ..In contrast, the R92Q variant of TNFR1 behaved like the wild-type receptor in all of these assays. The inflammatory phenotype of TRAPS may be due to consequences of mutant TNFR1 protein misfolding and ER retention...
  7. ncbi Hereditary periodic fever
    Keith M Hull
    N Engl J Med 346:1415-6; author reply 1415-6. 2002