Weichun Huang

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Accurate anchoring alignment of divergent sequences
    Weichun Huang
    Biostatistics Branch, The National Institute of Environmental Health Sciences NIH, Research Triangle Park, NC 27709, USA
    Bioinformatics 22:29-34. 2006
  2. ncbi request reprint IUTA: a tool for effectively detecting differential isoform usage from RNA-Seq data
    Liang Niu
    Biostatistics Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    BMC Genomics 15:862. 2014
  3. pmc Characterization of constitutive CTCF/cohesin loci: a possible role in establishing topological domains in mammalian genomes
    Yuanyuan Li
    Biostatistics Branch, National Institute of Environmental Health Sciences, Research Triangle Park, Durham, NC 27709, USA
    BMC Genomics 14:553. 2013
  4. pmc Optimized mixed Markov models for motif identification
    Weichun Huang
    Bioinformatics Research Center, North Carolina State University, Raleigh, NC 27606, USA
    BMC Bioinformatics 7:279. 2006
  5. pmc Phylogenetic simulation of promoter evolution: estimation and modeling of binding site turnover events and assessment of their impact on alignment tools
    Weichun Huang
    Institute for Genome Sciences and Policy, Duke University, Durham, NC 27708, USA
    Genome Biol 8:R225. 2007
  6. pmc EagleView: a genome assembly viewer for next-generation sequencing technologies
    Weichun Huang
    Department of Biology, Boston College, Chestnut Hill, Massachusetts 02467, USA
    Genome Res 18:1538-43. 2008

Collaborators

Detail Information

Publications6

  1. ncbi request reprint Accurate anchoring alignment of divergent sequences
    Weichun Huang
    Biostatistics Branch, The National Institute of Environmental Health Sciences NIH, Research Triangle Park, NC 27709, USA
    Bioinformatics 22:29-34. 2006
    ..Obtaining high quality alignments of divergent homologous sequences for cross-species sequence comparison remains a challenge...
  2. ncbi request reprint IUTA: a tool for effectively detecting differential isoform usage from RNA-Seq data
    Liang Niu
    Biostatistics Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    BMC Genomics 15:862. 2014
    ....
  3. pmc Characterization of constitutive CTCF/cohesin loci: a possible role in establishing topological domains in mammalian genomes
    Yuanyuan Li
    Biostatistics Branch, National Institute of Environmental Health Sciences, Research Triangle Park, Durham, NC 27709, USA
    BMC Genomics 14:553. 2013
    ..It remains unclear whether a subset of CTCF binding sites plays a functional role in establishing/maintaining chromatin topological domains...
  4. pmc Optimized mixed Markov models for motif identification
    Weichun Huang
    Bioinformatics Research Center, North Carolina State University, Raleigh, NC 27606, USA
    BMC Bioinformatics 7:279. 2006
    ..Identifying functional elements, such as transcriptional factor binding sites, is a fundamental step in reconstructing gene regulatory networks and remains a challenging issue, largely due to limited availability of training samples...
  5. pmc Phylogenetic simulation of promoter evolution: estimation and modeling of binding site turnover events and assessment of their impact on alignment tools
    Weichun Huang
    Institute for Genome Sciences and Policy, Duke University, Durham, NC 27708, USA
    Genome Biol 8:R225. 2007
    ..As an alternative, we introduce a flexible new simulation system, Phylogenetic Simulation of Promoter Evolution (PSPE), designed to study functional site turnovers in regulatory sequences...
  6. pmc EagleView: a genome assembly viewer for next-generation sequencing technologies
    Weichun Huang
    Department of Biology, Boston College, Chestnut Hill, Massachusetts 02467, USA
    Genome Res 18:1538-43. 2008
    ..EagleView has been used in our own lab and by over 100 research labs worldwide for next-generation sequence analyses. The EagleView software is freely available for not-for-profit use at http://bioinformatics.bc.edu/marthlab/EagleView...