Weichun Huang

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc ART: a next-generation sequencing read simulator
    Weichun Huang
    Biostatistics Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Bioinformatics 28:593-4. 2012
  2. pmc Efficiently identifying genome-wide changes with next-generation sequencing data
    Weichun Huang
    Biostatistics Branch, National Institute of Environmental Health Sciences, RTP, NC 27709, USA
    Nucleic Acids Res 39:e130. 2011
  3. pmc PAVIS: a tool for Peak Annotation and Visualization
    Weichun Huang
    Biostatistics Branch and the Integrative Bioinformatics Group, National Institute of Environmental Health Sciences, Durham, NC 27709, USA
    Bioinformatics 29:3097-9. 2013
  4. ncbi request reprint Accurate anchoring alignment of divergent sequences
    Weichun Huang
    Biostatistics Branch, The National Institute of Environmental Health Sciences NIH, Research Triangle Park, NC 27709, USA
    Bioinformatics 22:29-34. 2006
  5. pmc Characterization of constitutive CTCF/cohesin loci: a possible role in establishing topological domains in mammalian genomes
    Yuanyuan Li
    Biostatistics Branch, National Institute of Environmental Health Sciences, Research Triangle Park, Durham, NC 27709, USA
    BMC Genomics 14:553. 2013
  6. pmc Posttranscriptional regulation of cell-cell interaction protein-encoding transcripts by Zfs1p in Schizosaccharomyces pombe
    Melissa L Wells
    Laboratory of Signal Transduction, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA
    Mol Cell Biol 32:4206-14. 2012

Collaborators

Detail Information

Publications6

  1. pmc ART: a next-generation sequencing read simulator
    Weichun Huang
    Biostatistics Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
    Bioinformatics 28:593-4. 2012
    ..ART also allows the flexibility to use customized read error model parameters and quality profiles...
  2. pmc Efficiently identifying genome-wide changes with next-generation sequencing data
    Weichun Huang
    Biostatistics Branch, National Institute of Environmental Health Sciences, RTP, NC 27709, USA
    Nucleic Acids Res 39:e130. 2011
    ..In particular, we show that our novel and robust 'parsimony' normalization method is superior to the widely-used 'tagRatio' method. Our software EpiCenter is freely available to the public...
  3. pmc PAVIS: a tool for Peak Annotation and Visualization
    Weichun Huang
    Biostatistics Branch and the Integrative Bioinformatics Group, National Institute of Environmental Health Sciences, Durham, NC 27709, USA
    Bioinformatics 29:3097-9. 2013
    ..PAVIS enables rapid, and easy examination and cross-comparison of the genomic context and potential functions of the underlying genomic elements, thus supporting downstream hypothesis generation...
  4. ncbi request reprint Accurate anchoring alignment of divergent sequences
    Weichun Huang
    Biostatistics Branch, The National Institute of Environmental Health Sciences NIH, Research Triangle Park, NC 27709, USA
    Bioinformatics 22:29-34. 2006
    ..Obtaining high quality alignments of divergent homologous sequences for cross-species sequence comparison remains a challenge...
  5. pmc Characterization of constitutive CTCF/cohesin loci: a possible role in establishing topological domains in mammalian genomes
    Yuanyuan Li
    Biostatistics Branch, National Institute of Environmental Health Sciences, Research Triangle Park, Durham, NC 27709, USA
    BMC Genomics 14:553. 2013
    ..It remains unclear whether a subset of CTCF binding sites plays a functional role in establishing/maintaining chromatin topological domains...
  6. pmc Posttranscriptional regulation of cell-cell interaction protein-encoding transcripts by Zfs1p in Schizosaccharomyces pombe
    Melissa L Wells
    Laboratory of Signal Transduction, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA
    Mol Cell Biol 32:4206-14. 2012
    ..These data suggest that Zfs1p can both directly and indirectly regulate the levels of transcripts involved in cell-cell adhesion in this species...