Ping Hu

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Planning of randomized early detection trials
    Ping Hu
    Biometry Research Group, National Cancer Institute, Executive Plaza North, Suite 3131, 6130 Executive Blvd, MSC 7354, Bethesda, MD 20892 7354, USA
    Stat Methods Med Res 13:491-506. 2004
  2. ncbi request reprint Cloning and characterization of a novel gene, SHPRH, encoding a conserved putative protein with SNF2/helicase and PHD-finger domains from the 6q24 region
    Raman Sood
    Cancer Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Genomics 82:153-61. 2003
  3. ncbi request reprint Identification of six novel genes by experimental validation of GeneMachine predicted genes
    Izabela Makalowska
    Genome Technology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA
    Gene 284:203-13. 2002
  4. ncbi request reprint Physical and transcript map of the hereditary prostate cancer region at xq27
    Dietrich A Stephan
    Cancer Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Genomics 79:41-50. 2002
  5. pmc Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression
    Ping Hu
    Department of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, 702 Light Hall, Nashville, TN 37232 0615, USA
    Mol Cell Biol 26:3071-84. 2006
  6. pmc ES cell pluripotency and germ-layer formation require the SWI/SNF chromatin remodeling component BAF250a
    Xiaolin Gao
    Cardiovascular Research Center, Massachusetts General Hospital, Harvard Medical School, Richard Simches Research Center, 185 Cambridge Street, Boston, MA 02114, USA
    Proc Natl Acad Sci U S A 105:6656-61. 2008
  7. ncbi request reprint Critical role of endogenous Akt/IAPs and MEK1/ERK pathways in counteracting endoplasmic reticulum stress-induced cell death
    Ping Hu
    Howard Hughes Medical Institute, Department of Molecular Physiology and Biophysics
    J Biol Chem 279:49420-9. 2004
  8. pmc Small molecule regulators of autophagy identified by an image-based high-throughput screen
    Lihong Zhang
    State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Road, Shanghai 200032, China
    Proc Natl Acad Sci U S A 104:19023-8. 2007
  9. ncbi request reprint Factors associated with human small aggressive non small cell lung cancer
    C Martin Tammemagi
    Department of Community Health Sciences, Brock University, 500 Glenridge Avenue, St Catharines, Ontario, Canada L2S 3A1
    Cancer Epidemiol Biomarkers Prev 16:2082-9. 2007
  10. ncbi request reprint Phase III study of standard combination versus rotating regimen of induction chemotherapy in patients with hormone insensitive metastatic breast cancer: an Eastern Cooperative Oncology Group Intergroup Study (E3185)
    Kishan J Pandya
    University of Rochester, James P Wilmot Cancer Center, Rochester, New York 14642, USA
    Am J Clin Oncol 30:113-25. 2007

Collaborators

  • Marvin Zelen
  • Izabela Makalowska
  • Raman Sood
  • Andreas D Baxevanis
  • Jing Li
  • Hong Zhu
  • Zhong Wang
  • C Martin Tammemagi
  • Jeffrey Trent
  • Yohey Suzuki
  • Kishan J Pandya
  • Randal Kaufman
  • Harley H McAdams
  • C K Osborne
  • Jing Yang
  • Bi Zhi Shi
  • Xing Zhong Wu
  • Xiaolin Gao
  • Patrick T McGrath
  • Lihong Zhang
  • Li Zhang
  • Jun Zhang
  • Fu Zhong Xue
  • Martin M Oken
  • Zhang Han
  • Dietrich A Stephan
  • Fang Ming Deng
  • Peri Tate
  • Robert Tjian
  • William C Skarnes
  • Heling Pan
  • Yan Hao
  • Nathan J Hillson
  • Antonio A Iniesta
  • Junying Yuan
  • Meng How Tan
  • Lucy Shapiro
  • Xin Xie
  • Dawei Ma
  • Jia Yu
  • Albert D Yu
  • Wenqing Cai
  • Alison K Hottes
  • Honglak Lee
  • Hongjun Wang
  • Yongzhe Che
  • Hongxu Qi
  • Yaoting Yu
  • Deling Kong
  • Shuhua Guo
  • Lailiang Ou
  • Fei Geng
  • Jie Zhen Wang
  • Pei Jie He
  • Steven Peace
  • William Hocking
  • Paul A Kvale
  • Pamela M Marcus
  • Philip C Prorok
  • Guo Rong Li
  • Jill Cordes
  • John K Gohagan
  • Thomas L Riley
  • Thomas M Beck
  • David L Levin
  • Stephen D Winslow
  • Chih Chi Andrew Hu
  • Daofeng Ni
  • Christiane M Robbins
  • Derek Gildea
  • Elizabeth M Gillanders
  • Joan E Bailey-Wilson
  • Shirin S Joseph
  • Mervi Heiskanen
  • Jeffrey R Smith
  • Pawandeep Dhami
  • Steve Mumm
  • Tanya M Teslovich
  • Alison J Coffey
  • Rolland Reinbold
  • Lorie Smith
  • Helen E Steingruber
  • Olli P Kallioneimi
  • Tung Tien Sun
  • John D Carpten
  • Katheryn A Resing
  • Ileana Zucchi
  • Ge Zhou
  • Gareth R Howell
  • Robert D Burk

Detail Information

Publications22

  1. ncbi request reprint Planning of randomized early detection trials
    Ping Hu
    Biometry Research Group, National Cancer Institute, Executive Plaza North, Suite 3131, 6130 Executive Blvd, MSC 7354, Bethesda, MD 20892 7354, USA
    Stat Methods Med Res 13:491-506. 2004
    ..Both families of designs significantly reduce the power. Power calculations are made for two clinical trials, which actually used these two designs...
  2. ncbi request reprint Cloning and characterization of a novel gene, SHPRH, encoding a conserved putative protein with SNF2/helicase and PHD-finger domains from the 6q24 region
    Raman Sood
    Cancer Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Genomics 82:153-61. 2003
    ..We have identified one truncating and three missense mutations, thus suggesting SHPRH as a possible candidate for the tumor suppressor gene...
  3. ncbi request reprint Identification of six novel genes by experimental validation of GeneMachine predicted genes
    Izabela Makalowska
    Genome Technology Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA
    Gene 284:203-13. 2002
    ..Our studies support the feasibility of identifying novel genes from regions of interest using draft human genome sequence...
  4. ncbi request reprint Physical and transcript map of the hereditary prostate cancer region at xq27
    Dietrich A Stephan
    Cancer Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Genomics 79:41-50. 2002
    ..These transcriptional units represent candidate genes for HPCX and multiple other hereditary diseases at Xq26.3-q27.3...
  5. pmc Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression
    Ping Hu
    Department of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, 702 Light Hall, Nashville, TN 37232 0615, USA
    Mol Cell Biol 26:3071-84. 2006
    ..Thus, ER stress induces two signals, namely TNF-alpha induction and TRAF2 down-regulation. They work in concert to amplify ER-initiated apoptotic signaling through the membrane death receptor...
  6. pmc ES cell pluripotency and germ-layer formation require the SWI/SNF chromatin remodeling component BAF250a
    Xiaolin Gao
    Cardiovascular Research Center, Massachusetts General Hospital, Harvard Medical School, Richard Simches Research Center, 185 Cambridge Street, Boston, MA 02114, USA
    Proc Natl Acad Sci U S A 105:6656-61. 2008
    ..Our results suggest that BAF250a is a key component of the gene regulatory machinery in ES cells controlling self-renewal, differentiation, and cell lineage decisions...
  7. ncbi request reprint Critical role of endogenous Akt/IAPs and MEK1/ERK pathways in counteracting endoplasmic reticulum stress-induced cell death
    Ping Hu
    Howard Hughes Medical Institute, Department of Molecular Physiology and Biophysics
    J Biol Chem 279:49420-9. 2004
    ..These results represent the first demonstration that activation of endogenous Akt/IAPs and MEK/ERK plays a critical role in controlling cell survival by resisting ER stress-induced cell death signaling...
  8. pmc Small molecule regulators of autophagy identified by an image-based high-throughput screen
    Lihong Zhang
    State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Road, Shanghai 200032, China
    Proc Natl Acad Sci U S A 104:19023-8. 2007
    ..Our studies suggest the possibility that some of these drugs may be useful for the treatment of Huntington's and other human diseases associated with the accumulation of misfolded proteins...
  9. ncbi request reprint Factors associated with human small aggressive non small cell lung cancer
    C Martin Tammemagi
    Department of Community Health Sciences, Brock University, 500 Glenridge Avenue, St Catharines, Ontario, Canada L2S 3A1
    Cancer Epidemiol Biomarkers Prev 16:2082-9. 2007
    ..Such small aggressive NSCLCs (SA-NSCLC) are no longer resectable with curative intent, carry a grave prognosis, and may involve unique biological pathways. This is a study of factors associated with SA-NSCLC...
  10. ncbi request reprint Phase III study of standard combination versus rotating regimen of induction chemotherapy in patients with hormone insensitive metastatic breast cancer: an Eastern Cooperative Oncology Group Intergroup Study (E3185)
    Kishan J Pandya
    University of Rochester, James P Wilmot Cancer Center, Rochester, New York 14642, USA
    Am J Clin Oncol 30:113-25. 2007
    ....
  11. ncbi request reprint High-throughput identification of transcription start sites, conserved promoter motifs and predicted regulons
    Patrick T McGrath
    Department of Physics, Stanford University, Varian Physics, 382 Via Pueblo Mall, Stanford, California 94305, USA
    Nat Biotechnol 25:584-92. 2007
    ..Using these motifs, we predict coregulated genes. We verified novel promoter motifs that regulate stress-response genes, including those responding to uranium challenge, a stress-response sigma factor and a stress-response noncoding RNA...
  12. ncbi request reprint Engineering of vascular grafts with genetically modified bone marrow mesenchymal stem cells on poly (propylene carbonate) graft
    Jun Zhang
    The Key Laboratory of Bioactive Materials, Ministry of Education, College of Life Science, Nankai University, Tianjin China
    Artif Organs 30:898-905. 2006
    ..The use of MSCs and therapeutic genes in tissue engineering of blood vessels could be helpful in improving vessel regeneration and patency...
  13. pmc Uroplakin IIIb, a urothelial differentiation marker, dimerizes with uroplakin Ib as an early step of urothelial plaque assembly
    Fang Ming Deng
    Epithelial Biology Unit, Ronald O Perelman Department of Dermatology, New York University School of Medicine, New York, NY 10016, USA
    J Cell Biol 159:685-94. 2002
    ....
  14. ncbi request reprint Baseline chest radiograph for lung cancer detection in the randomized Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial
    Martin M Oken
    Hubert H Humphrey Cancer Center, North Memorial Medical Center, Robbinsdale, MN 55422, USA
    J Natl Cancer Inst 97:1832-9. 2005
    ..We report lung cancer detection results of the baseline screening round...
  15. pmc Whole-genome transcriptional analysis of heavy metal stresses in Caulobacter crescentus
    Ping Hu
    Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mail Stop 70A3317, Berkeley, CA 94720, USA
    J Bacteriol 187:8437-49. 2005
    ..Several differentially regulated transcripts from regions previously not known to encode proteins were identified, demonstrating the advantage of evaluating the transcriptome by using whole-genome microarrays...
  16. ncbi request reprint FADDdel-GFP modified mouse insulinoma cells counteract the cytotoxicity of reactive T cells
    Ping Hu
    Department of Immunology, Tongji Medical College of Huazhong University of Science and Technology, Wuhan 430030, China
    Cell Mol Immunol 1:383-6. 2004
    ..The results showed that NIT modified by pFADDdel-GFP obviously resisted cytotoxicity mediated by special T cells. Therefore, it may be useful in the prevention or treatment of IDDM by intervening Fas-FasL pathway...
  17. ncbi request reprint [Bilirubin induced apoptosis of human neuroblastoma cell line SH-SY5Y and affected the mitochondrial membrane potential]
    Zhang Han
    Department of Otorhinolaryngology, Peking Union Medical College Hospital, PUMC and CAMS, Beijing 100730, China
    Zhonghua Er Bi Yan Hou Ke Za Zhi 37:243-6. 2002
    ..To study whether bilirubin induces apoptosis of human neuroblastoma cell line SH-SY5Y and affects the mitochondrial membrane potential...
  18. ncbi request reprint The "Kriging" model of spatial genetic structure in human population genetics
    Fu Zhong Xue
    The Institute of Epidemiology and Medical Statistics, Shandong University, Ji nan 250012, China
    Yi Chuan Xue Bao 32:219-33. 2005
    ....
  19. ncbi request reprint Gal3ST-2 involved in tumor metastasis process by regulation of adhesion ability to selectins and expression of integrins
    Bi Zhi Shi
    Department of Biochemistry, Shanghai Medical College, Fudan University, Shanghai 200032, PR China
    Biochem Biophys Res Commun 332:934-40. 2005
    ..These results suggested that Gal3ST-2 was involved in tumor metastasis process by regulation of adhesion ability to selectins and expression of integrins...
  20. ncbi request reprint A minimal RNA polymerase III transcription system from human cells reveals positive and negative regulatory roles for CK2
    Ping Hu
    Howard Hughes Medical Institute, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA
    Mol Cell 12:699-709. 2003
    ....
  21. ncbi request reprint CK2 phosphorylation of Bdp1 executes cell cycle-specific RNA polymerase III transcription repression
    Ping Hu
    Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA
    Mol Cell 16:81-92. 2004
    ..Thus, CK2 is directed to phosphorylate different targets within the basal pol III transcription machinery at different times during the cell cycle, with opposite transcriptional effects...
  22. ncbi request reprint Inhibitory effects of N-(4-hydrophenyl) retinamide on liver cancer and malignant melanoma cells
    Xing Zhong Wu
    Department of Biochemistry and Molecular Biology, Shanghai Medical College, Fudan University, Shanghai 200032, China
    World J Gastroenterol 11:5763-9. 2005
    ....