Lifang Hou

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Genetic polymorphisms in alcohol metabolism, alcohol intake and the risk of stomach cancer in Warsaw, Poland
    Fang Fang Zhang
    Department of Epidemiology, School of Public Health, University of North Texas Health Science Center, Fort Worth, TX 76107, USA
    Int J Cancer 121:2060-4. 2007
  2. ncbi request reprint Polymorphisms in Th1-type cell-mediated response genes and risk of gastric cancer
    L Hou
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, EPS 8123, Bethesda, MD 20852 7242, USA
    Carcinogenesis 28:118-23. 2007
  3. ncbi request reprint Commuting physical activity and risk of colon cancer in Shanghai, China
    Lifang Hou
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7240, USA
    Am J Epidemiol 160:860-7. 2004
  4. ncbi request reprint CYP1A1 Val462 and NQO1 Ser187 polymorphisms, cigarette use, and risk for colorectal adenoma
    Lifang Hou
    Department of Human and Health Services, Division of Cancer Epidemiology and Genetics, Pediatric Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 7240, USA
    Carcinogenesis 26:1122-8. 2005
  5. pmc Body mass index and colon cancer risk in Chinese people: menopause as an effect modifier
    Lifang Hou
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Blvd EPS Suite 511, MSC 7240, Bethesda, MD 20892 7240, USA
    Eur J Cancer 42:84-90. 2006
  6. ncbi request reprint CYP17 MspA1 polymorphism and risk of biliary tract cancers and gallstones: a population-based study in Shanghai, China
    Lifang Hou
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, DHHS, Rockville MD 20852 7236, USA
    Int J Cancer 118:2847-53. 2006
  7. pmc Body mass index, agricultural pesticide use, and cancer incidence in the Agricultural Health Study cohort
    Gabriella Andreotti
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, DHHS, 6120 Executive Blvd, EPS 8011, MSC 7240, Bethesda, MD 20892, USA
    Cancer Causes Control 21:1759-75. 2010
  8. pmc Cancer incidence among pesticide applicators exposed to dicamba in the agricultural health study
    Claudine Samanic
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20852, USA
    Environ Health Perspect 114:1521-6. 2006
  9. ncbi request reprint Interleukin-8 polymorphisms are not associated with gastric cancer risk in a Polish population
    Sharon A Savage
    Section of Genomic Variation, Pediatric Oncology Branch, National Cancer Institute, Advanced Technology Center, 8717 Grovemont Circle, Bethesda, MD 20892 4605, USA
    Cancer Epidemiol Biomarkers Prev 15:589-91. 2006
  10. pmc Pendimethalin exposure and cancer incidence among pesticide applicators
    Lifang Hou
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20852, USA
    Epidemiology 17:302-7. 2006

Detail Information

Publications23

  1. ncbi request reprint Genetic polymorphisms in alcohol metabolism, alcohol intake and the risk of stomach cancer in Warsaw, Poland
    Fang Fang Zhang
    Department of Epidemiology, School of Public Health, University of North Texas Health Science Center, Fort Worth, TX 76107, USA
    Int J Cancer 121:2060-4. 2007
    ..Furthermore, heavy drinkers of alcohol who were genetically prone to accumulate acetaldehyde may face an increased risk of stomach cancer...
  2. ncbi request reprint Polymorphisms in Th1-type cell-mediated response genes and risk of gastric cancer
    L Hou
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, EPS 8123, Bethesda, MD 20852 7242, USA
    Carcinogenesis 28:118-23. 2007
    ..IL1A (-889 C>T) and the three examined IL12A variants were unrelated to gastric cancer risk. Our findings suggest that two Th1-related polymorphisms (TNFA -308 A>G and IFNGR2 Ex7-128 C>T) may increase the risk of gastric cancer...
  3. ncbi request reprint Commuting physical activity and risk of colon cancer in Shanghai, China
    Lifang Hou
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7240, USA
    Am J Epidemiol 160:860-7. 2004
    ..54 for men; OR = 7.42, 95% CI: 2.84, 10.01 for women). Our results suggest that regular and frequent physical activity over a long period of time protects from colon cancer and significantly modifies the body mass index-associated risk...
  4. ncbi request reprint CYP1A1 Val462 and NQO1 Ser187 polymorphisms, cigarette use, and risk for colorectal adenoma
    Lifang Hou
    Department of Human and Health Services, Division of Cancer Epidemiology and Genetics, Pediatric Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 7240, USA
    Carcinogenesis 26:1122-8. 2005
    ..002). In summary, joint carriage of CYP1A1 Val(462) and NQO1 Ser(187) alleles, particularly in smokers, was related to colorectal adenoma risk, with a propensity for formation of multiple lesions...
  5. pmc Body mass index and colon cancer risk in Chinese people: menopause as an effect modifier
    Lifang Hou
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Blvd EPS Suite 511, MSC 7240, Bethesda, MD 20892 7240, USA
    Eur J Cancer 42:84-90. 2006
    ..91) and 0.7 (95% CI 0.5-0.95), respectively. Our findings suggest that BMI predicts colon cancer risk in both genders. Among women, however, the risk is modified by menopause status, possibly through altered endogenous oestrogen levels...
  6. ncbi request reprint CYP17 MspA1 polymorphism and risk of biliary tract cancers and gallstones: a population-based study in Shanghai, China
    Lifang Hou
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, DHHS, Rockville MD 20852 7236, USA
    Int J Cancer 118:2847-53. 2006
    ....
  7. pmc Body mass index, agricultural pesticide use, and cancer incidence in the Agricultural Health Study cohort
    Gabriella Andreotti
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, DHHS, 6120 Executive Blvd, EPS 8011, MSC 7240, Bethesda, MD 20892, USA
    Cancer Causes Control 21:1759-75. 2010
    ..87, 95% CI = 0.82-0.92) but was null in users of carbofuran (p-interaction = 0.02). These findings suggest that certain pesticides may modify the effects of BMI on the risks of colon and lung cancers...
  8. pmc Cancer incidence among pesticide applicators exposed to dicamba in the agricultural health study
    Claudine Samanic
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20852, USA
    Environ Health Perspect 114:1521-6. 2006
    ..We evaluated cancer incidence among pesticide applicators exposed to dicamba in the Agricultural Health Study, a prospective cohort of licensed pesticide applicators in North Carolina and Iowa...
  9. ncbi request reprint Interleukin-8 polymorphisms are not associated with gastric cancer risk in a Polish population
    Sharon A Savage
    Section of Genomic Variation, Pediatric Oncology Branch, National Cancer Institute, Advanced Technology Center, 8717 Grovemont Circle, Bethesda, MD 20892 4605, USA
    Cancer Epidemiol Biomarkers Prev 15:589-91. 2006
  10. pmc Pendimethalin exposure and cancer incidence among pesticide applicators
    Lifang Hou
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20852, USA
    Epidemiology 17:302-7. 2006
    ..We evaluated the incidence of cancer in relation to reported pendimethelin use among pesticide applicators in the Agricultural Health Study, a prospective cohort of licensed pesticide applicators in Iowa and North Carolina...
  11. ncbi request reprint Genetic polymorphisms in folate metabolism and the risk of stomach cancer
    Fang Fang Zhang
    Division of Cancer Epidemiology and Genetics, Advanced Technology Center, National Cancer Institute, Gaithersburg, Maryland, USA
    Cancer Epidemiol Biomarkers Prev 16:115-21. 2007
    ..Our study did not identify strong genetic determinants in the folate metabolism pathway for stomach cancer risk...
  12. pmc Genetic variants in T helper cell type 1, 2 and 3 pathways and gastric cancer risk in a Polish population
    Rajeev Mahajan
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA
    Jpn J Clin Oncol 38:626-33. 2008
    ..7-1.3) for C/T and 0.6 (95% CI, 0.3-1.0) T/T carriers compared with C/C carriers (P = 0.03). These results suggest that IL5 rs2069812 and IL7R rs1389832, rs1494556 and rs1494555 polymorphisms may contribute to gastric cancer etiology...
  13. pmc Polymorphisms in estrogen- and androgen-metabolizing genes and the risk of gastric cancer
    Neal D Freedman
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Rockville, MD 20852, USA
    Carcinogenesis 30:71-7. 2009
    ..These findings should be interpreted cautiously until replicated in other studies...
  14. pmc Agricultural pesticide use and pancreatic cancer risk in the Agricultural Health Study Cohort
    Gabriella Andreotti
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Int J Cancer 124:2495-500. 2009
    ..Organochlorines were not associated with an excess risk of pancreatic cancer in this study. These findings suggest that herbicides, particularly pendimethalin and EPTC, may be associated with pancreatic cancer...
  15. pmc Heterocyclic aromatic amine pesticide use and human cancer risk: results from the U.S. Agricultural Health Study
    Stella Koutros
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20852, USA
    Int J Cancer 124:1206-12. 2009
    ..The use of imazethapyr and other imidazolinone compounds should continue to be evaluated for potential risk to humans...
  16. ncbi request reprint Cancer incidence among pesticide applicators exposed to metolachlor in the Agricultural Health Study
    Jennifer A Rusiecki
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20892, USA
    Int J Cancer 118:3118-23. 2006
    ....
  17. ncbi request reprint Metabolic polymorphisms, smoking, and oral cancer in Puerto Rico
    Heng Xie
    Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, MD 20892, USA
    Oncol Res 14:315-20. 2004
    ..4). In conclusion, cigarette use significantly increased the risk of oral cancer in this population. The GSTM1-present genotype was associated with higher tobacco-associated risk for oral cancer among heavy smokers than the null genotype...
  18. ncbi request reprint Facial papules, spontaneous pneumothorax, and renal tumors
    Jorge R Toro
    Genetic Epidemiology Branch, National Cancer Institute, Bethesda, Maryland 20892 7231, USA
    J Am Acad Dermatol 48:111-4. 2003
  19. pmc Environmental chemical exposures and human epigenetics
    Lifang Hou
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    Int J Epidemiol 41:79-105. 2012
    ..To complete our discussion, we also briefly summarize the diseases that have been linked to environmental chemicals-related epigenetic changes...
  20. ncbi request reprint COX1 and COX2 polymorphisms and gastric cancer risk in a Polish population
    Lifang Hou
    Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, 680 N Lake Shore Drive, Chicago, IL 60611, USA
    Anticancer Res 27:4243-7. 2007
    ..Although a number of studies on the polymorphisms in COX1 and COX2 genes in association with risks for a number of cancers have been conducted, their relation to gastric cancer has not been well studied...
  21. ncbi request reprint Mannose-binding lectin-2 genetic variation and stomach cancer risk
    Andrea Baccarelli
    EPOCA Epidemiology Research Centre, Maggiore Hospital IRCCS Foundation, University of Milan, Milan, Italy
    Int J Cancer 119:1970-5. 2006
    ..5, 95% CI 1.6-7.6; p = 0.001). Our findings suggest that the codon 52 D MBL2 variant causing a cysteine > arginine replacement, but not B and C variants producing glycine substitutions, is specifically associated with gastric cancer risk...
  22. ncbi request reprint Sun exposure and non-Hodgkin lymphoma: a population-based, case-control study
    Lori K Soni
    Department of Preventive Medicine, Northwestern University Medical School, Chicago, IL, United States
    Eur J Cancer 43:2388-95. 2007
    ..In conclusion, our data suggest that total hours of sun exposure is associated with a lower risk of NHL, and the inverse association is not modified by vitamin D intake, is stronger among farmer, and may vary by subtypes...
  23. pmc Air pollution, smoking, and plasma homocysteine
    Andrea Baccarelli
    Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts 02215, USA
    Environ Health Perspect 115:176-81. 2007
    ..Air pollution exposure induces short-term inflammatory changes that may determine hyperhomocysteinemia, particularly in the presence of a preexisting proinflammatory status such as that found in cigarette smokers...