J A Hoppin

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Lifetime organophosphorous insecticide use among private pesticide applicators in the Agricultural Health Study
    Jane A Hoppin
    Epidemiology Branch, NIEHS, NIH, DHHS, Research Triangle Park, North Carolina 27709 2233, USA
    J Expo Sci Environ Epidemiol 22:584-92. 2012
  2. ncbi request reprint Male reproductive effects of phthalates: an emerging picture
    Jane A Hoppin
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC 27709, USA
    Epidemiology 14:259-60. 2003
  3. ncbi request reprint Pesticides associated with wheeze among commercial pesticide applicators in the Agricultural Health Study
    Jane A Hoppin
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, US Department of Health and Human Services, Research Triangle Park, NC 27709 2233, USA
    Am J Epidemiol 163:1129-37. 2006
  4. ncbi request reprint Impact of urine preservation methods and duration of storage on measured levels of environmental contaminants
    Jane A Hoppin
    Epidemiology Branch, NIEHS, NIH, DHHS, Research Triangle Park, NC, USA
    J Expo Sci Environ Epidemiol 16:39-48. 2006
  5. ncbi request reprint Integrating exposure measurements into epidemiologic studies in agriculture
    Jane A Hoppin
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709 2233, USA
    Scand J Work Environ Health 31:115-7; discussion 63-5. 2005
  6. pmc Phthalate exposure and pulmonary function
    Jane A Hoppin
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health DHHS, PO Box 12233, Research Triangle Park, NC 27709 2233, USA
    Environ Health Perspect 112:571-4. 2004
  7. ncbi request reprint Diesel exhaust, solvents, and other occupational exposures as risk factors for wheeze among farmers
    Jane A Hoppin
    Epidemiology Branch and Biostatistics, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC 27709 2233, USA
    Am J Respir Crit Care Med 169:1308-13. 2004
  8. pmc Pesticides and other agricultural factors associated with self-reported farmer's lung among farm residents in the Agricultural Health Study
    Jane A Hoppin
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709 2233, USA
    Occup Environ Med 64:334-41. 2007
  9. ncbi request reprint Pesticides and adult respiratory outcomes in the agricultural health study
    Jane A Hoppin
    Epidemiology Branch, National Institute of Environmental Healh Science, NIH, DHHS, Research Triangle Park, NC 27709 2233, USA
    Ann N Y Acad Sci 1076:343-54. 2006
  10. pmc Environmental exposure assessment of pesticides in farmworker homes
    Jane A Hoppin
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709, USA
    Environ Health Perspect 114:929-35. 2006

Collaborators

Detail Information

Publications83

  1. pmc Lifetime organophosphorous insecticide use among private pesticide applicators in the Agricultural Health Study
    Jane A Hoppin
    Epidemiology Branch, NIEHS, NIH, DHHS, Research Triangle Park, North Carolina 27709 2233, USA
    J Expo Sci Environ Epidemiol 22:584-92. 2012
    ..Information on farmers' OP use enhances our ability to characterize and understand the potential health effects of multiple OP exposures...
  2. ncbi request reprint Male reproductive effects of phthalates: an emerging picture
    Jane A Hoppin
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC 27709, USA
    Epidemiology 14:259-60. 2003
  3. ncbi request reprint Pesticides associated with wheeze among commercial pesticide applicators in the Agricultural Health Study
    Jane A Hoppin
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, US Department of Health and Human Services, Research Triangle Park, NC 27709 2233, USA
    Am J Epidemiol 163:1129-37. 2006
    ..40, 95% CI: 1.24, 4.65). These results add to the emerging literature linking organophosphate insecticides and respiratory health and suggest a role for chlorimuron-ethyl...
  4. ncbi request reprint Impact of urine preservation methods and duration of storage on measured levels of environmental contaminants
    Jane A Hoppin
    Epidemiology Branch, NIEHS, NIH, DHHS, Research Triangle Park, NC, USA
    J Expo Sci Environ Epidemiol 16:39-48. 2006
    ..The precision of the laboratory measurements was high allowing us to observe small differences, which may not be important when categorizing individuals into broader exposure groups...
  5. ncbi request reprint Integrating exposure measurements into epidemiologic studies in agriculture
    Jane A Hoppin
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709 2233, USA
    Scand J Work Environ Health 31:115-7; discussion 63-5. 2005
    ..Future work to develop exposure metrics that incorporate both chemical and behavior characteristics for all farmworkers and farm residents will further improve epidemiologic studies in agriculture...
  6. pmc Phthalate exposure and pulmonary function
    Jane A Hoppin
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health DHHS, PO Box 12233, Research Triangle Park, NC 27709 2233, USA
    Environ Health Perspect 112:571-4. 2004
    ..Our results suggest that MBP and MEP, but not MEHP, may influence pulmonary function among adult males...
  7. ncbi request reprint Diesel exhaust, solvents, and other occupational exposures as risk factors for wheeze among farmers
    Jane A Hoppin
    Epidemiology Branch and Biostatistics, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC 27709 2233, USA
    Am J Respir Crit Care Med 169:1308-13. 2004
    ..89, 3.73), an indication of daily solvent exposure. These results add to the growing body of evidence of adverse respiratory effects of diesel exposure on the lung and suggest exposure to solvents may contribute as well...
  8. pmc Pesticides and other agricultural factors associated with self-reported farmer's lung among farm residents in the Agricultural Health Study
    Jane A Hoppin
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709 2233, USA
    Occup Environ Med 64:334-41. 2007
    ..Farmer's lung, or hypersensitivity pneumonitis, is an important contributor to respiratory morbidity among farmers...
  9. ncbi request reprint Pesticides and adult respiratory outcomes in the agricultural health study
    Jane A Hoppin
    Epidemiology Branch, National Institute of Environmental Healh Science, NIH, DHHS, Research Triangle Park, NC 27709 2233, USA
    Ann N Y Acad Sci 1076:343-54. 2006
    ..00-2.19) for farmers and 1.96 (95% CI = 1.05-3.66) for commercial applicators. Our wheeze results are consistent with recent animal models that support a role for organophosphates and respiratory outcomes...
  10. pmc Environmental exposure assessment of pesticides in farmworker homes
    Jane A Hoppin
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709, USA
    Environ Health Perspect 114:929-35. 2006
    ..This mini-monograph discusses the strategies used to assess pesticide exposures, presents limitations in the available data for farmworkers, and suggests research needs for future studies of pesticide exposure among farmworker families...
  11. pmc Animal production and wheeze in the Agricultural Health Study: interactions with atopy, asthma, and smoking
    J A Hoppin
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC 27709 2233, USA
    Occup Environ Med 60:e3. 2003
    ..Exposure to animals, their feeds, and by-products contribute to respiratory symptoms among farmers...
  12. pmc Pesticides and atopic and nonatopic asthma among farm women in the Agricultural Health Study
    Jane A Hoppin
    NIEHS Epidemiology Branch, MD A3 05, P O Box 12233, Research Triangle Park, NC 27709 2233, USA
    Am J Respir Crit Care Med 177:11-8. 2008
    ..Risk factors for asthma among farm women are understudied...
  13. pmc Pesticide use and chronic bronchitis among farmers in the Agricultural Health Study
    Jane A Hoppin
    Epidemiology Branch, National Institute of Environmental Health Sciences, NIH, DHHS, Research Triangle Park, North Carolina 27709 2233, USA
    Am J Ind Med 50:969-79. 2007
    ..Farmers have increased risk for chronic bronchitis. Few investigators have considered pesticides...
  14. ncbi request reprint Accuracy of self-reported pesticide use duration information from licensed pesticide applicators in the Agricultural Health Study
    Jane A Hoppin
    Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709 2233, USA
    J Expo Anal Environ Epidemiol 12:313-8. 2002
    ..While we are unable to validate directly the accuracy of a respondent's use of pesticides, this analysis suggests that participants provide plausible information regarding their pesticide use...
  15. pmc Pesticide use and adult-onset asthma among male farmers in the Agricultural Health Study
    J A Hoppin
    Epidemiology Branch, National Institute of Environmental Health Sciences, Epidemiology Branch, MD A3 05, PO Box 12233, Research Triangle Park, NC 27709 2233, USA
    Eur Respir J 34:1296-303. 2009
    ..There was little evidence that allergy alone was driving these associations. In conclusion, pesticides may be an overlooked contributor to asthma risk among farmers...
  16. pmc Questionnaire predictors of atopy in a US population sample: findings from the National Health and Nutrition Examination Survey, 2005-2006
    Jane A Hoppin
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709 2233, USA
    Am J Epidemiol 173:544-52. 2011
    ....
  17. pmc Measurement variability associated with KXRF bone lead measurement in young adults
    J A Hoppin
    Harvard School of Public Health, Boston, Massachusetts, USA
    Environ Health Perspect 108:239-42. 2000
    ..Because of the importance of conducting additional research on adolescent lead toxicity, further improvements to the precision of KXRF measurement are needed...
  18. ncbi request reprint Agricultural exposure history among African-American farmers in Georgia
    J A Hoppin
    Rollins School of Public Health, Emory University, Atlanta, Georgia, USA
    J Toxicol Environ Health A 63:237-41. 2001
    ..Better characterization of regionally specific farming history and individual farming practices will facilitate studies of the health effects of farming...
  19. pmc Reproducibility of urinary phthalate metabolites in first morning urine samples
    Jane A Hoppin
    Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709 2233, USA
    Environ Health Perspect 110:515-8. 2002
    ..5 for mBzP. These results suggest that even with the short half-lives of phthalates, women's patterns of exposure may be sufficiently stable to assign an exposure level based on a single first morning void urine measurement...
  20. ncbi request reprint Chemical predictors of wheeze among farmer pesticide applicators in the Agricultural Health Study
    Jane A Hoppin
    Epidemiology Branch and Biostatistics Branch, National Institute of Environmental Health Sciences NIH, Research Triangle Park, NC 27709 2233, USA
    Am J Respir Crit Care Med 165:683-9. 2002
    ..5 (95% CI 1.2,1.9). Inclusion of crops and animals into these models did not significantly alter the observed OR. These associations, though small, suggest an independent role for specific pesticides in respiratory symptoms of farmers...
  21. ncbi request reprint Cancer incidence among pesticide applicators exposed to metolachlor in the Agricultural Health Study
    Jennifer A Rusiecki
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20892, USA
    Int J Cancer 118:3118-23. 2006
    ....
  22. pmc Fonofos exposure and cancer incidence in the agricultural health study
    Rajeev Mahajan
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland 20852, USA
    Environ Health Perspect 114:1838-42. 2006
    ..A previous investigation in this cohort linked exposure to the organophosphate fonofos with incident prostate cancer in subjects with family history of prostate cancer...
  23. ncbi request reprint Neurologic symptoms in licensed pesticide applicators in the Agricultural Health Study
    F Kamel
    National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, PO Box 12233, Research Triangle Park, NC 27709, USA
    Hum Exp Toxicol 26:243-50. 2007
    ..These results suggest that neurologic symptoms are associated with cumulative exposure to moderate levels of organophosphate and organochlorine insecticides, regardless of recent exposure or history of poisoning...
  24. ncbi request reprint Cancer incidence among male pesticide applicators in the Agricultural Health Study cohort exposed to diazinon
    Laura E Beane Freeman
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20892, USA
    Am J Epidemiol 162:1070-9. 2005
    ..Because these results were based on small numbers, additional analyses are necessary as more cases accrue to clarify whether diazinon is associated with cancer risk in humans...
  25. ncbi request reprint Retinal degeneration and other eye disorders in wives of farmer pesticide applicators enrolled in the agricultural health study
    Ellen F Kirrane
    CODA, Inc, Durham, NC 27709, USA
    Am J Epidemiol 161:1020-9. 2005
    ..These findings suggest that exposure to some fungicides and other pesticides may increase the risk of retinal degeneration and warrant further investigation...
  26. ncbi request reprint Malathion exposure and the incidence of cancer in the agricultural health study
    Matthew R Bonner
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD 20892, USA
    Am J Epidemiol 166:1023-34. 2007
    ..Although the rate ratios for melanoma were reduced, small numbers and lack of experimental evidence suggest that the observed reductions may have arisen by chance...
  27. ncbi request reprint Cancer incidence among pesticide applicators exposed to alachlor in the Agricultural Health Study
    Won Jin Lee
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20852, USA
    Am J Epidemiol 159:373-80. 2004
    ..Our findings suggest a possible association between alachlor application and incidence of lymphohematopoietic cancers among applicators in the Agricultural Health Study...
  28. ncbi request reprint Carbaryl exposure and incident cancer in the Agricultural Health Study
    Rajeev Mahajan
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20852, USA
    Int J Cancer 121:1799-805. 2007
    ..No associations were observed with other examined cancer sites. Because the observed results were not hypothesized a priori and because of limited study of their biological plausibility, they should be interpreted with caution...
  29. ncbi request reprint Use of a life events calendar approach to elicit occupational history from farmers
    J A Hoppin
    Department of Environmental and Occupational Health, Rollins School of Public Health, Emory University, Atlanta, Georgia 30322, USA
    Am J Ind Med 34:470-6. 1998
    ..One method to assist in recall is the "life events calendar," a cognitive tool based on the subject's own life history to help anchor occupational activities in time...
  30. ncbi request reprint Cancer incidence among pesticide applicators exposed to chlorpyrifos in the Agricultural Health Study
    Won Jin Lee
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Rockville, MD 20852, USA
    J Natl Cancer Inst 96:1781-9. 2004
    ..We evaluated the incidence of cancer among pesticide applicators exposed to chlorpyrifos in the Agricultural Health Study, a prospective cohort study of licensed pesticide applicators in Iowa and North Carolina...
  31. pmc Cancer incidence among pesticide applicators exposed to cyanazine in the agricultural health study
    Shannon M Lynch
    Clinical and Genetic Epidemiology Research Branch, Epidemiology and Genetics Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, Maryland 20892, USA
    Environ Health Perspect 114:1248-52. 2006
    ..We evaluated cancer incidence in cyanazine-exposed pesticide applicators among the 57,311 licensed pesticide applicators in the Agricultural Health Study (AHS)...
  32. pmc Effects of self-reported health conditions and pesticide exposures on probability of follow-up in a prospective cohort study
    Martha P Montgomery
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709, USA
    Am J Ind Med 53:486-96. 2010
    ..We investigated the potential for selection bias due to non-participation in the follow-up of a large prospective cohort study...
  33. ncbi request reprint Comparing questionnaire-based methods to assess occupational silica exposure
    Christine G Parks
    Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA
    Epidemiology 15:433-41. 2004
    ....
  34. ncbi request reprint A quantitative approach for estimating exposure to pesticides in the Agricultural Health Study
    Mustafa Dosemeci
    National Cancer Institute, NIH, Bethesda, MD, USA
    Ann Occup Hyg 46:245-60. 2002
    ....
  35. pmc Phorate exposure and incidence of cancer in the agricultural health study
    Rajeev Mahajan
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland 20852, USA
    Environ Health Perspect 114:1205-9. 2006
    ..We recently reported a link between use of the organophosphate pesticide phorate and risk of prostate cancer among applicators with a family history of prostate cancer in the Agricultural Health Study (AHS)...
  36. ncbi request reprint Reduced fertility among overweight and obese men
    Markku Sallmen
    Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA
    Epidemiology 17:520-3. 2006
    ..Overweight and obese men have been reported to have lower sperm counts and hormonal changes, but data are lacking regarding effects on couple fertility...
  37. pmc Cancer incidence among pesticide applicators exposed to butylate in the Agricultural Health Study (AHS)
    Shannon M Lynch
    Epidemiology and Genetics Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20852, USA
    Environ Res 109:860-8. 2009
    ..27, 95% CI=1.18-4.37; NHL: RR(LD)=3.44, 95% CI=1.29-9.21). Our analysis did not find meaningful associations for other cancers analyzed. Further study is warranted for AL, NHL and prostate cancers...
  38. pmc S-ethyl-N,N-dipropylthiocarbamate exposure and cancer incidence among male pesticide applicators in the agricultural health study: a prospective cohort
    Dana M Van Bemmel
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland, USA
    Environ Health Perspect 116:1541-6. 2008
    ..The U.S. Environmental Protection Agency reports that EPTC is most likely not a human carcinogen; however, the previous epidemiologic data on EPTC exposure and cancer risk were limited...
  39. pmc Chronic bronchitis among nonsmoking farm women in the agricultural health study
    Martin Valcin
    Epidemiology, National Institute of Environmental Health Sciences, NIH, DHHS, Research Triangle Park, NC 27709 2233, USA
    J Occup Environ Med 49:574-83. 2007
    ..The purpose of this study was to examine agricultural risk factors for chronic bronchitis among nonsmoking farm women...
  40. pmc Pesticides and myocardial infarction incidence and mortality among male pesticide applicators in the Agricultural Health Study
    Katherine T Mills
    Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709 2233, USA
    Am J Epidemiol 170:892-900. 2009
    ..In a population with low risk for myocardial infarction, the authors observed little evidence of increased risk of myocardial infarction mortality or nonfatal myocardial infarction associated with the occupational use of pesticides...
  41. ncbi request reprint Pesticide use and breast cancer risk among farmers' wives in the agricultural health study
    Lawrence S Engel
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    Am J Epidemiol 161:121-35. 2005
    ..Further follow-up of this cohort should help clarify the relation between pesticide exposure and breast cancer risk...
  42. ncbi request reprint Pesticide exposure and timing of menopause: the Agricultural Health Study
    Sherry L Farr
    Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
    Am J Epidemiol 163:731-42. 2006
    ..78, 0.97) and by approximately 5 months for women who used hormonally active pesticides (hazard ratio = 0.77, 95% confidence interval: 0.65, 0.92). Pesticide use may be associated with a later age at menopause...
  43. pmc Pendimethalin exposure and cancer incidence among pesticide applicators
    Lifang Hou
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20852, USA
    Epidemiology 17:302-7. 2006
    ..We evaluated the incidence of cancer in relation to reported pendimethelin use among pesticide applicators in the Agricultural Health Study, a prospective cohort of licensed pesticide applicators in Iowa and North Carolina...
  44. ncbi request reprint Cancer incidence among pesticide applicators exposed to atrazine in the Agricultural Health Study
    Jennifer A Rusiecki
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20892 7240, USA
    J Natl Cancer Inst 96:1375-82. 2004
    ..We evaluated cancer incidence in atrazine-exposed pesticide applicators among 53,943 participants in the Agricultural Health Study, a prospective cohort study of licensed pesticide applicators in Iowa and North Carolina...
  45. pmc Body mass index, effect modifiers, and risk of pancreatic cancer: a pooled study of seven prospective cohorts
    Li Jiao
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    Cancer Causes Control 21:1305-14. 2010
    ..To investigate whether the positive association of body mass index (BMI, kg/m(2)) with risk of pancreatic cancer is modified by age, sex, smoking status, physical activity, and history of diabetes...
  46. pmc Fertility and exposure to solvents among families in the Agricultural Health Study
    M Sallmen
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Human Health Services, Research Triangle Park, North Carolina, USA
    Occup Environ Med 63:469-75. 2006
    ..Several studies have reported associations between solvent exposure and reduced female fertility, but the evidence is inconclusive for male fertility...
  47. pmc Disease and injury among participants in the Agricultural Health Study
    A Blair
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Executive Plaza South, Room 8118, Bethesda, Maryland 20892, USA
    J Agric Saf Health 11:141-50. 2005
    ..The study can provide data to address many health issues in the agricultural community. The study investigators welcome collaboration with interested scientists...
  48. doi request reprint Cancer incidence among pesticide applicators exposed to trifluralin in the Agricultural Health Study
    Daehee Kang
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, DHHS, 6120 Executive Blvd EPS 8000, Rockville, MD 20852, USA
    Environ Res 107:271-6. 2008
    ..Although there was a possible link between trifluralin exposure and colon cancer, small numbers and inconsistencies in dose-response and subgroup analyses indicate that this may be a chance finding...
  49. pmc An interlaboratory study of perfluorinated alkyl compound levels in human plasma
    Matthew P Longnecker
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, P O Box 12233, MD A3 05, Research Triangle Park, NC 27709, USA
    Environ Res 107:152-9. 2008
    ..Considering the degree of between-subject variation in levels among people in background-exposed populations, the results indicate that biomarker-based epidemiologic studies of associations with health could have reasonable precision...
  50. pmc Meat and meat mutagens and risk of prostate cancer in the Agricultural Health Study
    Stella Koutros
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, EPS 8111, Rockville, MD 20852, USA
    Cancer Epidemiol Biomarkers Prev 17:80-7. 2008
    ..96-1.59) and 1.20 (95% CI, 0.93-1.55), respectively] when the highest quintile was compared with the lowest. In conclusion, well and very well done meat was associated with an increased risk for prostate cancer in this cohort...
  51. pmc Dichlorvos exposure and human cancer risk: results from the Agricultural Health Study
    Stella Koutros
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Rockville, MD 20852, USA
    Cancer Causes Control 19:59-65. 2008
    ..We evaluated cancer risk from DDVP (2,2-Dichloroethenyl dimethylphosphate) exposure among pesticide applicators enrolled in the Agricultural Health Study (AHS) cohort...
  52. ncbi request reprint Use of agricultural pesticides and prostate cancer risk in the Agricultural Health Study cohort
    Michael C R Alavanja
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20892, USA
    Am J Epidemiol 157:800-14. 2003
    ..Important family history-pesticide interactions were observed...
  53. doi request reprint Within-person variability in urinary phthalate metabolite concentrations: measurements from specimens after long-term frozen storage
    Donna Day Baird
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709, USA
    J Expo Sci Environ Epidemiol 20:169-75. 2010
    ..These findings support the use of stored urine specimens collected during the relevant stage of human pregnancy to investigate the influence of phthalate exposures on later outcomes...
  54. pmc Within-person variability in urinary bisphenol A concentrations: measurements from specimens after long-term frozen storage
    Pablo A Nepomnaschy
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, USA
    Environ Res 109:734-7. 2009
    ..Our aims were to evaluate the stability of BPA in specimens after 22-24 years of storage and to measure within-person temporal variability in urinary BPA...
  55. pmc Agricultural pesticide use and pancreatic cancer risk in the Agricultural Health Study Cohort
    Gabriella Andreotti
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Int J Cancer 124:2495-500. 2009
    ..Organochlorines were not associated with an excess risk of pancreatic cancer in this study. These findings suggest that herbicides, particularly pendimethalin and EPTC, may be associated with pancreatic cancer...
  56. pmc Body-mass index and mortality among 1.46 million white adults
    Amy Berrington de Gonzalez
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
    N Engl J Med 363:2211-9. 2010
    ....
  57. pmc Pesticide exposure and risk of monoclonal gammopathy of undetermined significance in the Agricultural Health Study
    Ola Landgren
    Division of Cancer Epidemiology and Genetics, Medical Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Blood 113:6386-91. 2009
    ..In summary, the prevalence of MGUS among pesticide applicators was twice that in a population-based sample of men from Minnesota, adding support to the hypothesis that specific pesticides are causatively linked to myelomagenesis...
  58. pmc Pesticide use modifies the association between genetic variants on chromosome 8q24 and prostate cancer
    Stella Koutros
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, Maryland 20852, USA
    Cancer Res 70:9224-33. 2010
    ..This is the first report of effect modification between 8q24 and an environmental exposure on prostate cancer risk...
  59. pmc Body mass index, agricultural pesticide use, and cancer incidence in the Agricultural Health Study cohort
    Gabriella Andreotti
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, DHHS, 6120 Executive Blvd, EPS 8011, MSC 7240, Bethesda, MD 20892, USA
    Cancer Causes Control 21:1759-75. 2010
    ..87, 95% CI = 0.82-0.92) but was null in users of carbofuran (p-interaction = 0.02). These findings suggest that certain pesticides may modify the effects of BMI on the risks of colon and lung cancers...
  60. ncbi request reprint Occupational exposure to crystalline silica and risk of systemic lupus erythematosus: a population-based, case-control study in the southeastern United States
    Christine G Parks
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Durham, North Carolina 27709, USA
    Arthritis Rheum 46:1840-50. 2002
    ..We undertook this population-based study to examine the association between occupational silica exposure and SLE in the southeastern US...
  61. ncbi request reprint Health effects of chronic pesticide exposure: cancer and neurotoxicity
    Michael C R Alavanja
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Rockville, Maryland 20892, USA
    Annu Rev Public Health 25:155-97. 2004
    ..Improving epidemiology studies and integrating this information with toxicology data will allow the human health risks of pesticide exposure to be more accurately judged by public health policy makers...
  62. pmc Occupational exposure to carbofuran and the incidence of cancer in the Agricultural Health Study
    Matthew R Bonner
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA
    Environ Health Perspect 113:285-9. 2005
    ..Although carbamate pesticides are suspected human carcinogens, these results should be interpreted cautiously because there was no a priori hypothesis specifically linking carbofuran to lung cancer...
  63. ncbi request reprint Pesticides and lung cancer risk in the agricultural health study cohort
    Michael C R Alavanja
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20892, USA
    Am J Epidemiol 160:876-85. 2004
    ..The usage levels in this cohort are considerably higher than those typically experienced by the general population. An excess risk among spouses directly exposed to pesticides could not be evaluated at this time...
  64. pmc Cancer incidence among pesticide applicators exposed to dicamba in the agricultural health study
    Claudine Samanic
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20852, USA
    Environ Health Perspect 114:1521-6. 2006
    ..We evaluated cancer incidence among pesticide applicators exposed to dicamba in the Agricultural Health Study, a prospective cohort of licensed pesticide applicators in North Carolina and Iowa...
  65. pmc Occupational exposure to organochlorine insecticides and cancer incidence in the Agricultural Health Study
    Mark P Purdue
    Division of Cancer Epidemiology and Genetics, Occupational and Environmental Epidemiology Branch, National Cancer Institute, National Institutes of Health, Rockville, Maryland 20852, USA
    Int J Cancer 120:642-9. 2007
    ....
  66. pmc Association of pesticide exposure with neurologic dysfunction and disease
    Freya Kamel
    National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709, USA
    Environ Health Perspect 112:950-8. 2004
    ..Major unresolved issues include the relative importance of acute and chronic exposure, the effect of moderate exposure in the absence of poisoning, and the relationship of pesticide-related neurotoxicity to neurodegenerative disease...
  67. ncbi request reprint Mortality among participants in the agricultural health study
    Aaron Blair
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD, USA
    Ann Epidemiol 15:279-85. 2005
    ..This analysis of the Agricultural Health Study cohort assesses the mortality experience of licensed pesticide applicators and their spouses...
  68. ncbi request reprint Bayesian methods for highly correlated exposure data
    Richard F MacLehose
    Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    Epidemiology 18:199-207. 2007
    ..We compare these 4 hierarchical regression methods and demonstrate their application in an example estimating the association of herbicides with retinal degeneration among wives of pesticide applicators...
  69. ncbi request reprint Pesticide exposure and self-reported gestational diabetes mellitus in the Agricultural Health Study
    Tina M Saldana
    Epidemiology Branch, National Institute of Environmental Health Sciences, P O Box 12233, MD A3 05, Research Triangle Park, NC 27709, USA
    Diabetes Care 30:529-34. 2007
    ..To examine the association between pesticide use during pregnancy and gestational diabetes mellitus (GDM) among wives of licensed pesticide applicators...
  70. ncbi request reprint Cancer incidence in the agricultural health study
    Michael C R Alavanja
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20892, USA
    Scand J Work Environ Health 31:39-45; discussion 5-7. 2005
    ..This large, prospective cohort study of private applicators, commercial applicators, and spouses of farmer applicators was undertaken to ascertain the etiology of cancers elevated in agriculture...
  71. pmc Neurologic symptoms in licensed private pesticide applicators in the agricultural health study
    Freya Kamel
    National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC 27709, USA
    Environ Health Perspect 113:877-82. 2005
    ....
  72. ncbi request reprint Factor analysis of pesticide use patterns among pesticide applicators in the Agricultural Health Study
    Claudine Samanic
    National Cancer Institute, Division of Cancer Epidemiology and Genetics, Bethesda, Maryland, USA
    J Expo Anal Environ Epidemiol 15:225-33. 2005
    ..This heterogeneity in exposure patterns may be used to guide etiologic studies of health effects of farmers and other groups exposed to pesticides...
  73. pmc Cancer incidence among glyphosate-exposed pesticide applicators in the Agricultural Health Study
    Anneclaire J De Roos
    Program in Epidemiology, Fred Hutchinson Cancer Research Center and the Department of Epidemiology, University of Washington, Seattle, Washington 98109, USA
    Environ Health Perspect 113:49-54. 2005
    ..Given the widespread use of glyphosate, future analyses of the AHS will allow further examination of long-term health effects, including less common cancers...
  74. pmc Induction of asthma and the environment: what we know and need to know
    MaryJane K Selgrade
    National Health and Environmental Effects Research Laboratory, U S Environmental Protection Agency, Research Triangle Park, NC 27711, USA
    Environ Health Perspect 114:615-9. 2006
    ..Research to address these questions could have a significant public health and economic impact that would be well worth the investment...
  75. ncbi request reprint Patterns of pesticide use and their determinants among wives of farmer pesticide applicators in the Agricultural Health Study
    Ellen F Kirrane
    Coda Inc, Durham, North Carolina, USA
    J Occup Environ Med 46:856-65. 2004
    ..Farm women reporting the heaviest pesticide use could exacerbate their exposure by engaging in practices that could increase pesticide contact...
  76. pmc Farmworker exposure to pesticides: methodologic issues for the collection of comparable data
    Thomas A Arcury
    Department of Family and Community Medicine, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157 1084, USA
    Environ Health Perspect 114:923-8. 2006
    ....
  77. pmc The biobank of the Norwegian Mother and Child Cohort Study: a resource for the next 100 years
    Kjersti S Rønningen
    Division of Epidemiology, Norwegian Institute of Public Health, 4404 Nydalen, N 0403 Oslo, Norway
    Eur J Epidemiol 21:619-25. 2006
    ..In designing specimen repositories, efforts need to balance future needs for samples with logistical constraints necessary to process and store samples in a timely fashion...
  78. pmc Depression and pesticide exposures in female spouses of licensed pesticide applicators in the agricultural health study cohort
    Cheryl Beseler
    Colorado Injury Control Research Center, Department of Psychology, Colorado State University, Fort Collins, Colorado 80523, USA
    J Occup Environ Med 48:1005-13. 2006
    ..This nested case-control study evaluated the association between depression and pesticide exposure among women...
  79. pmc Reporting pesticide assessment results to farmworker families: development, implementation, and evaluation of a risk communication strategy
    Sara A Quandt
    Department of Public Health Sciences, Piedmont Plaza II, Wake Forest University School of Medicine, Winston Salem, NC 27157 1063, USA
    Environ Health Perspect 112:636-42. 2004
    ..We review the strengths and weaknesses of such an approach and suggest areas for future research in risk communication to communities affected by environmental health risks...
  80. ncbi request reprint Prevalence of exposure to solvents, metals, grain dust, and other hazards among farmers in the Agricultural Health Study
    Joseph Coble
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Occupational Epidemiology Branch, 6120 Executive Boulevard, EPS8110, Rockville, Maryland 20892 7240, USA
    J Expo Anal Environ Epidemiol 12:418-26. 2002
    ..Confounding risk ratios calculated for these activities suggest that the magnitude of bias due to confounding is likely to be minimal...
  81. pmc Cancer risk and parental pesticide application in children of Agricultural Health Study participants
    Kori B Flower
    Robert Wood Johnson Clinical Scholars Program and Division of Community Pediatrics, Department of Pediatrics, School of Public Health, University of North Carolina, Chapel Hill, NC 27599 7105, USA
    Environ Health Perspect 112:631-5. 2004
    ..Identification of excess lymphoma risk suggests that farm exposures including pesticides may play a role in the etiology of childhood lymphoma...
  82. pmc Mortality among pesticide applicators exposed to chlorpyrifos in the Agricultural Health Study
    Won Jin Lee
    Department of Preventive Medicine, College of Medicine, Korea University, Seoul, Korea
    Environ Health Perspect 115:528-34. 2007
    ..Chlorpyrifos is one of the most widely used organophosphate insecticides in the United States. Although the toxicity of chlorpyrifos has been extensively studied in animals, the epidemiologic data are limited...
  83. pmc Agricultural and residential pesticides in wipe samples from farmworker family residences in North Carolina and Virginia
    Sara A Quandt
    Department of Public Health Sciences, Wake Forest University School of Medicine, Medical Center Boulevard, Piedmont Plaza II, Suite 512, Winston Salem, NC 27157 1063, USA
    Environ Health Perspect 112:382-7. 2004
    ..Although the likelihood of agricultural pesticide exposure has been considered high for farmworker families, these results indicate that residential pesticide use and exposure in this population merit further study...