Research Topics
| J A HoppinSummaryAffiliation: National Institutes of Health Country: USA Publications
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Publications
Lifetime organophosphorous insecticide use among private pesticide applicators in the Agricultural Health StudyJane A Hoppin
Epidemiology Branch, NIEHS, NIH, DHHS, Research Triangle Park, North Carolina 27709 2233, USA
J Expo Sci Environ Epidemiol 22:584-92. 2012..Information on farmers' OP use enhances our ability to characterize and understand the potential health effects of multiple OP exposures...
Male reproductive effects of phthalates: an emerging pictureJane A Hoppin
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC 27709, USA
Epidemiology 14:259-60. 2003
Pesticides associated with wheeze among commercial pesticide applicators in the Agricultural Health StudyJane A Hoppin
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, US Department of Health and Human Services, Research Triangle Park, NC 27709 2233, USA
Am J Epidemiol 163:1129-37. 2006..40, 95% CI: 1.24, 4.65). These results add to the emerging literature linking organophosphate insecticides and respiratory health and suggest a role for chlorimuron-ethyl...
Impact of urine preservation methods and duration of storage on measured levels of environmental contaminantsJane A Hoppin
Epidemiology Branch, NIEHS, NIH, DHHS, Research Triangle Park, NC, USA
J Expo Sci Environ Epidemiol 16:39-48. 2006..The precision of the laboratory measurements was high allowing us to observe small differences, which may not be important when categorizing individuals into broader exposure groups...
Integrating exposure measurements into epidemiologic studies in agricultureJane A Hoppin
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709 2233, USA
Scand J Work Environ Health 31:115-7; discussion 63-5. 2005..Future work to develop exposure metrics that incorporate both chemical and behavior characteristics for all farmworkers and farm residents will further improve epidemiologic studies in agriculture...
Phthalate exposure and pulmonary functionJane A Hoppin
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health DHHS, PO Box 12233, Research Triangle Park, NC 27709 2233, USA
Environ Health Perspect 112:571-4. 2004..Our results suggest that MBP and MEP, but not MEHP, may influence pulmonary function among adult males...
Diesel exhaust, solvents, and other occupational exposures as risk factors for wheeze among farmersJane A Hoppin
Epidemiology Branch and Biostatistics, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC 27709 2233, USA
Am J Respir Crit Care Med 169:1308-13. 2004..89, 3.73), an indication of daily solvent exposure. These results add to the growing body of evidence of adverse respiratory effects of diesel exposure on the lung and suggest exposure to solvents may contribute as well...
Pesticides and other agricultural factors associated with self-reported farmer's lung among farm residents in the Agricultural Health StudyJane A Hoppin
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709 2233, USA
Occup Environ Med 64:334-41. 2007..Farmer's lung, or hypersensitivity pneumonitis, is an important contributor to respiratory morbidity among farmers...
Pesticides and adult respiratory outcomes in the agricultural health studyJane A Hoppin
Epidemiology Branch, National Institute of Environmental Healh Science, NIH, DHHS, Research Triangle Park, NC 27709 2233, USA
Ann N Y Acad Sci 1076:343-54. 2006..00-2.19) for farmers and 1.96 (95% CI = 1.05-3.66) for commercial applicators. Our wheeze results are consistent with recent animal models that support a role for organophosphates and respiratory outcomes...
Environmental exposure assessment of pesticides in farmworker homesJane A Hoppin
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709, USA
Environ Health Perspect 114:929-35. 2006..This mini-monograph discusses the strategies used to assess pesticide exposures, presents limitations in the available data for farmworkers, and suggests research needs for future studies of pesticide exposure among farmworker families...
Animal production and wheeze in the Agricultural Health Study: interactions with atopy, asthma, and smokingJ A Hoppin
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC 27709 2233, USA
Occup Environ Med 60:e3. 2003..Exposure to animals, their feeds, and by-products contribute to respiratory symptoms among farmers...
Pesticides and atopic and nonatopic asthma among farm women in the Agricultural Health StudyJane A Hoppin
NIEHS Epidemiology Branch, MD A3 05, P O Box 12233, Research Triangle Park, NC 27709 2233, USA
Am J Respir Crit Care Med 177:11-8. 2008..Risk factors for asthma among farm women are understudied...
Pesticide use and chronic bronchitis among farmers in the Agricultural Health StudyJane A Hoppin
Epidemiology Branch, National Institute of Environmental Health Sciences, NIH, DHHS, Research Triangle Park, North Carolina 27709 2233, USA
Am J Ind Med 50:969-79. 2007..Farmers have increased risk for chronic bronchitis. Few investigators have considered pesticides...
Accuracy of self-reported pesticide use duration information from licensed pesticide applicators in the Agricultural Health StudyJane A Hoppin
Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709 2233, USA
J Expo Anal Environ Epidemiol 12:313-8. 2002..While we are unable to validate directly the accuracy of a respondent's use of pesticides, this analysis suggests that participants provide plausible information regarding their pesticide use...
Pesticide use and adult-onset asthma among male farmers in the Agricultural Health StudyJ A Hoppin
Epidemiology Branch, National Institute of Environmental Health Sciences, Epidemiology Branch, MD A3 05, PO Box 12233, Research Triangle Park, NC 27709 2233, USA
Eur Respir J 34:1296-303. 2009..There was little evidence that allergy alone was driving these associations. In conclusion, pesticides may be an overlooked contributor to asthma risk among farmers...
Questionnaire predictors of atopy in a US population sample: findings from the National Health and Nutrition Examination Survey, 2005-2006Jane A Hoppin
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709 2233, USA
Am J Epidemiol 173:544-52. 2011....
Measurement variability associated with KXRF bone lead measurement in young adultsJ A Hoppin
Harvard School of Public Health, Boston, Massachusetts, USA
Environ Health Perspect 108:239-42. 2000..Because of the importance of conducting additional research on adolescent lead toxicity, further improvements to the precision of KXRF measurement are needed...
Agricultural exposure history among African-American farmers in GeorgiaJ A Hoppin
Rollins School of Public Health, Emory University, Atlanta, Georgia, USA
J Toxicol Environ Health A 63:237-41. 2001..Better characterization of regionally specific farming history and individual farming practices will facilitate studies of the health effects of farming...
Reproducibility of urinary phthalate metabolites in first morning urine samplesJane A Hoppin
Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709 2233, USA
Environ Health Perspect 110:515-8. 2002..5 for mBzP. These results suggest that even with the short half-lives of phthalates, women's patterns of exposure may be sufficiently stable to assign an exposure level based on a single first morning void urine measurement...
Chemical predictors of wheeze among farmer pesticide applicators in the Agricultural Health StudyJane A Hoppin
Epidemiology Branch and Biostatistics Branch, National Institute of Environmental Health Sciences NIH, Research Triangle Park, NC 27709 2233, USA
Am J Respir Crit Care Med 165:683-9. 2002..5 (95% CI 1.2,1.9). Inclusion of crops and animals into these models did not significantly alter the observed OR. These associations, though small, suggest an independent role for specific pesticides in respiratory symptoms of farmers...
Cancer incidence among pesticide applicators exposed to metolachlor in the Agricultural Health StudyJennifer A Rusiecki
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20892, USA
Int J Cancer 118:3118-23. 2006....
Fonofos exposure and cancer incidence in the agricultural health studyRajeev Mahajan
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland 20852, USA
Environ Health Perspect 114:1838-42. 2006..A previous investigation in this cohort linked exposure to the organophosphate fonofos with incident prostate cancer in subjects with family history of prostate cancer...
Neurologic symptoms in licensed pesticide applicators in the Agricultural Health StudyF Kamel
National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, PO Box 12233, Research Triangle Park, NC 27709, USA
Hum Exp Toxicol 26:243-50. 2007..These results suggest that neurologic symptoms are associated with cumulative exposure to moderate levels of organophosphate and organochlorine insecticides, regardless of recent exposure or history of poisoning...
Cancer incidence among male pesticide applicators in the Agricultural Health Study cohort exposed to diazinonLaura E Beane Freeman
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20892, USA
Am J Epidemiol 162:1070-9. 2005..Because these results were based on small numbers, additional analyses are necessary as more cases accrue to clarify whether diazinon is associated with cancer risk in humans...
Retinal degeneration and other eye disorders in wives of farmer pesticide applicators enrolled in the agricultural health studyEllen F Kirrane
CODA, Inc, Durham, NC 27709, USA
Am J Epidemiol 161:1020-9. 2005..These findings suggest that exposure to some fungicides and other pesticides may increase the risk of retinal degeneration and warrant further investigation...
Malathion exposure and the incidence of cancer in the agricultural health studyMatthew R Bonner
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD 20892, USA
Am J Epidemiol 166:1023-34. 2007..Although the rate ratios for melanoma were reduced, small numbers and lack of experimental evidence suggest that the observed reductions may have arisen by chance...
Cancer incidence among pesticide applicators exposed to alachlor in the Agricultural Health StudyWon Jin Lee
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20852, USA
Am J Epidemiol 159:373-80. 2004..Our findings suggest a possible association between alachlor application and incidence of lymphohematopoietic cancers among applicators in the Agricultural Health Study...
Carbaryl exposure and incident cancer in the Agricultural Health StudyRajeev Mahajan
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20852, USA
Int J Cancer 121:1799-805. 2007..No associations were observed with other examined cancer sites. Because the observed results were not hypothesized a priori and because of limited study of their biological plausibility, they should be interpreted with caution...
Use of a life events calendar approach to elicit occupational history from farmersJ A Hoppin
Department of Environmental and Occupational Health, Rollins School of Public Health, Emory University, Atlanta, Georgia 30322, USA
Am J Ind Med 34:470-6. 1998..One method to assist in recall is the "life events calendar," a cognitive tool based on the subject's own life history to help anchor occupational activities in time...
Cancer incidence among pesticide applicators exposed to chlorpyrifos in the Agricultural Health StudyWon Jin Lee
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Rockville, MD 20852, USA
J Natl Cancer Inst 96:1781-9. 2004..18 (95% confidence interval = 1.31 to 3.64) times that of those with no chlorpyrifos exposure. CONCLUSION: Our findings suggest an association between chlorpyrifos use and incidence of lung cancer that deserves further evaluation...
Cancer incidence among pesticide applicators exposed to cyanazine in the agricultural health studyShannon M Lynch
Clinical and Genetic Epidemiology Research Branch, Epidemiology and Genetics Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, Maryland 20892, USA
Environ Health Perspect 114:1248-52. 2006..The number of sites was small for certain cancers, limiting any conclusion with regard to ovarian, breast, and some other cancers...
Effects of self-reported health conditions and pesticide exposures on probability of follow-up in a prospective cohort studyMartha P Montgomery
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709, USA
Am J Ind Med 53:486-96. 2010..We investigated the potential for selection bias due to non-participation in the follow-up of a large prospective cohort study...
Comparing questionnaire-based methods to assess occupational silica exposureChristine G Parks
Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA
Epidemiology 15:433-41. 2004....
A quantitative approach for estimating exposure to pesticides in the Agricultural Health StudyMustafa Dosemeci
National Cancer Institute, NIH, Bethesda, MD, USA
Ann Occup Hyg 46:245-60. 2002....
Phorate exposure and incidence of cancer in the agricultural health studyRajeev Mahajan
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland 20852, USA
Environ Health Perspect 114:1205-9. 2006..We recently reported a link between use of the organophosphate pesticide phorate and risk of prostate cancer among applicators with a family history of prostate cancer in the Agricultural Health Study (AHS)...
Reduced fertility among overweight and obese menMarkku Sallmen
Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA
Epidemiology 17:520-3. 2006..Overweight and obese men have been reported to have lower sperm counts and hormonal changes, but data are lacking regarding effects on couple fertility...
Cancer incidence among pesticide applicators exposed to butylate in the Agricultural Health Study (AHS)Shannon M Lynch
Epidemiology and Genetics Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20852, USA
Environ Res 109:860-8. 2009..27, 95% CI=1.18-4.37; NHL: RR(LD)=3.44, 95% CI=1.29-9.21). Our analysis did not find meaningful associations for other cancers analyzed. Further study is warranted for AL, NHL and prostate cancers...
S-ethyl-N,N-dipropylthiocarbamate exposure and cancer incidence among male pesticide applicators in the agricultural health study: a prospective cohortDana M Van Bemmel
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland, USA
Environ Health Perspect 116:1541-6. 2008..The U.S. Environmental Protection Agency reports that EPTC is most likely not a human carcinogen; however, the previous epidemiologic data on EPTC exposure and cancer risk were limited...
Chronic bronchitis among nonsmoking farm women in the agricultural health studyMartin Valcin
Epidemiology, National Institute of Environmental Health Sciences, NIH, DHHS, Research Triangle Park, NC 27709 2233, USA
J Occup Environ Med 49:574-83. 2007..The purpose of this study was to examine agricultural risk factors for chronic bronchitis among nonsmoking farm women...
Pesticides and myocardial infarction incidence and mortality among male pesticide applicators in the Agricultural Health StudyKatherine T Mills
Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709 2233, USA
Am J Epidemiol 170:892-900. 2009..In a population with low risk for myocardial infarction, the authors observed little evidence of increased risk of myocardial infarction mortality or nonfatal myocardial infarction associated with the occupational use of pesticides...
Pesticide use and breast cancer risk among farmers' wives in the agricultural health studyLawrence S Engel
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
Am J Epidemiol 161:121-35. 2005..Further follow-up of this cohort should help clarify the relation between pesticide exposure and breast cancer risk...
Pesticide exposure and timing of menopause: the Agricultural Health StudySherry L Farr
Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
Am J Epidemiol 163:731-42. 2006..78, 0.97) and by approximately 5 months for women who used hormonally active pesticides (hazard ratio = 0.77, 95% confidence interval: 0.65, 0.92). Pesticide use may be associated with a later age at menopause...
Pendimethalin exposure and cancer incidence among pesticide applicatorsLifang Hou
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20852, USA
Epidemiology 17:302-7. 2006..The trends for lung cancer risk were inconsistent for different exposure metrics. CONCLUSIONS: We did not find a clear association of lifetime pendimethalin exposure either with overall cancer incidence or with specific cancer sites...
Cancer incidence among pesticide applicators exposed to atrazine in the Agricultural Health StudyJennifer A Rusiecki
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20892-7240, USA
J Natl Cancer Inst 96:1375-82. 2004..However, further studies are warranted for tumor types in which there was a suggestion of trend (lung, bladder, non-Hodgkin lymphoma, and multiple myeloma)...
Body mass index, effect modifiers, and risk of pancreatic cancer: a pooled study of seven prospective cohortsLi Jiao
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
Cancer Causes Control 21:1305-14. 2010..To investigate whether the positive association of body mass index (BMI, kg/m(2)) with risk of pancreatic cancer is modified by age, sex, smoking status, physical activity, and history of diabetes...
Fertility and exposure to solvents among families in the Agricultural Health StudyM Sallmen
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Human Health Services, Research Triangle Park, North Carolina, USA
Occup Environ Med 63:469-75. 2006..Several studies have reported associations between solvent exposure and reduced female fertility, but the evidence is inconclusive for male fertility...
Disease and injury among participants in the Agricultural Health StudyA Blair
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Executive Plaza South, Room 8118, Bethesda, Maryland 20892, USA
J Agric Saf Health 11:141-50. 2005..The study can provide data to address many health issues in the agricultural community. The study investigators welcome collaboration with interested scientists...
Cancer incidence among pesticide applicators exposed to trifluralin in the Agricultural Health StudyDaehee Kang
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, DHHS, 6120 Executive Blvd EPS 8000, Rockville, MD 20852, USA
Environ Res 107:271-6. 2008..Although there was a possible link between trifluralin exposure and colon cancer, small numbers and inconsistencies in dose-response and subgroup analyses indicate that this may be a chance finding...
An interlaboratory study of perfluorinated alkyl compound levels in human plasmaMatthew P Longnecker
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, P O Box 12233, MD A3 05, Research Triangle Park, NC 27709, USA
Environ Res 107:152-9. 2008..Considering the degree of between-subject variation in levels among people in background-exposed populations, the results indicate that biomarker-based epidemiologic studies of associations with health could have reasonable precision...
Meat and meat mutagens and risk of prostate cancer in the Agricultural Health StudyStella Koutros
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, EPS 8111, Rockville, MD 20852, USA
Cancer Epidemiol Biomarkers Prev 17:80-7. 2008..96-1.59) and 1.20 (95% CI, 0.93-1.55), respectively] when the highest quintile was compared with the lowest. In conclusion, well and very well done meat was associated with an increased risk for prostate cancer in this cohort...
Dichlorvos exposure and human cancer risk: results from the Agricultural Health StudyStella Koutros
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Rockville, MD 20852, USA
Cancer Causes Control 19:59-65. 2008..We evaluated cancer risk from DDVP (2,2-Dichloroethenyl dimethylphosphate) exposure among pesticide applicators enrolled in the Agricultural Health Study (AHS) cohort...
Use of agricultural pesticides and prostate cancer risk in the Agricultural Health Study cohortMichael C R Alavanja
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20892, USA
Am J Epidemiol 157:800-14. 2003..Important family history-pesticide interactions were observed...
Within-person variability in urinary phthalate metabolite concentrations: measurements from specimens after long-term frozen storageDonna Day Baird
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709, USA
J Expo Sci Environ Epidemiol 20:169-75. 2010..These findings support the use of stored urine specimens collected during the relevant stage of human pregnancy to investigate the influence of phthalate exposures on later outcomes...
Within-person variability in urinary bisphenol A concentrations: measurements from specimens after long-term frozen storagePablo A Nepomnaschy
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC, USA
Environ Res 109:734-7. 2009..Our aims were to evaluate the stability of BPA in specimens after 22-24 years of storage and to measure within-person temporal variability in urinary BPA...
Agricultural pesticide use and pancreatic cancer risk in the Agricultural Health Study CohortGabriella Andreotti
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
Int J Cancer 124:2495-500. 2009..Organochlorines were not associated with an excess risk of pancreatic cancer in this study. These findings suggest that herbicides, particularly pendimethalin and EPTC, may be associated with pancreatic cancer...
Body-mass index and mortality among 1.46 million white adultsAmy Berrington de Gonzalez
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
N Engl J Med 363:2211-9. 2010....
Pesticide exposure and risk of monoclonal gammopathy of undetermined significance in the Agricultural Health StudyOla Landgren
Division of Cancer Epidemiology and Genetics, Medical Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
Blood 113:6386-91. 2009..In summary, the prevalence of MGUS among pesticide applicators was twice that in a population-based sample of men from Minnesota, adding support to the hypothesis that specific pesticides are causatively linked to myelomagenesis...
Pesticide use modifies the association between genetic variants on chromosome 8q24 and prostate cancerStella Koutros
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, Maryland 20852, USA
Cancer Res 70:9224-33. 2010..This is the first report of effect modification between 8q24 and an environmental exposure on prostate cancer risk...
Body mass index, agricultural pesticide use, and cancer incidence in the Agricultural Health Study cohortGabriella Andreotti
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, DHHS, 6120 Executive Blvd, EPS 8011, MSC 7240, Bethesda, MD 20892, USA
Cancer Causes Control 21:1759-75. 2010..87, 95% CI = 0.82-0.92) but was null in users of carbofuran (p-interaction = 0.02). These findings suggest that certain pesticides may modify the effects of BMI on the risks of colon and lung cancers...
Occupational exposure to crystalline silica and risk of systemic lupus erythematosus: a population-based, case-control study in the southeastern United StatesChristine G Parks
Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Durham, North Carolina 27709, USA
Arthritis Rheum 46:1840-50. 2002..We undertook this population-based study to examine the association between occupational silica exposure and SLE in the southeastern US...
Health effects of chronic pesticide exposure: cancer and neurotoxicityMichael C R Alavanja
Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Rockville, Maryland 20892, USA
Annu Rev Public Health 25:155-97. 2004..Improving epidemiology studies and integrating this information with toxicology data will allow the human health risks of pesticide exposure to be more accurately judged by public health policy makers...
Occupational exposure to carbofuran and the incidence of cancer in the Agricultural Health StudyMatthew R Bonner
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA
Environ Health Perspect 113:285-9. 2005..Although carbamate pesticides are suspected human carcinogens, these results should be interpreted cautiously because there was no a priori hypothesis specifically linking carbofuran to lung cancer...
Pesticides and lung cancer risk in the agricultural health study cohortMichael C R Alavanja
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20892, USA
Am J Epidemiol 160:876-85. 2004..The usage levels in this cohort are considerably higher than those typically experienced by the general population. An excess risk among spouses directly exposed to pesticides could not be evaluated at this time...
Cancer incidence among pesticide applicators exposed to dicamba in the agricultural health studyClaudine Samanic
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20852, USA
Environ Health Perspect 114:1521-6. 2006..There was no apparent risk for non-Hodgkin lymphoma. CONCLUSIONS: Although associations between exposure and lung and colon cancer were observed, we did not find clear evidence for an association between dicamba exposure and cancer risk...
Occupational exposure to organochlorine insecticides and cancer incidence in the Agricultural Health StudyMark P Purdue
Division of Cancer Epidemiology and Genetics, Occupational and Environmental Epidemiology Branch, National Cancer Institute, National Institutes of Health, Rockville, Maryland 20852, USA
Int J Cancer 120:642-9. 2007....
Association of pesticide exposure with neurologic dysfunction and diseaseFreya Kamel
National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709, USA
Environ Health Perspect 112:950-8. 2004..Major unresolved issues include the relative importance of acute and chronic exposure, the effect of moderate exposure in the absence of poisoning, and the relationship of pesticide-related neurotoxicity to neurodegenerative disease...
Mortality among participants in the agricultural health studyAaron Blair
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD, USA
Ann Epidemiol 15:279-85. 2005..This analysis of the Agricultural Health Study cohort assesses the mortality experience of licensed pesticide applicators and their spouses...
Bayesian methods for highly correlated exposure dataRichard F MacLehose
Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
Epidemiology 18:199-207. 2007..We compare these 4 hierarchical regression methods and demonstrate their application in an example estimating the association of herbicides with retinal degeneration among wives of pesticide applicators...
Pesticide exposure and self-reported gestational diabetes mellitus in the Agricultural Health StudyTina M Saldana
Epidemiology Branch, National Institute of Environmental Health Sciences, P O Box 12233, MD A3 05, Research Triangle Park, NC 27709, USA
Diabetes Care 30:529-34. 2007..To examine the association between pesticide use during pregnancy and gestational diabetes mellitus (GDM) among wives of licensed pesticide applicators...
Cancer incidence in the agricultural health studyMichael C R Alavanja
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20892, USA
Scand J Work Environ Health 31:39-45; discussion 5-7. 2005..This large, prospective cohort study of private applicators, commercial applicators, and spouses of farmer applicators was undertaken to ascertain the etiology of cancers elevated in agriculture...
Neurologic symptoms in licensed private pesticide applicators in the agricultural health studyFreya Kamel
National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, NC 27709, USA
Environ Health Perspect 113:877-82. 2005....
Factor analysis of pesticide use patterns among pesticide applicators in the Agricultural Health StudyClaudine Samanic
National Cancer Institute, Division of Cancer Epidemiology and Genetics, Bethesda, Maryland, USA
J Expo Anal Environ Epidemiol 15:225-33. 2005..This heterogeneity in exposure patterns may be used to guide etiologic studies of health effects of farmers and other groups exposed to pesticides...
Cancer incidence among glyphosate-exposed pesticide applicators in the Agricultural Health StudyAnneclaire J De Roos
Program in Epidemiology, Fred Hutchinson Cancer Research Center and the Department of Epidemiology, University of Washington, Seattle, Washington 98109, USA
Environ Health Perspect 113:49-54. 2005..Given the widespread use of glyphosate, future analyses of the AHS will allow further examination of long-term health effects, including less common cancers...
Induction of asthma and the environment: what we know and need to knowMaryJane K Selgrade
National Health and Environmental Effects Research Laboratory, U S Environmental Protection Agency, Research Triangle Park, NC 27711, USA
Environ Health Perspect 114:615-9. 2006..Research to address these questions could have a significant public health and economic impact that would be well worth the investment...
Patterns of pesticide use and their determinants among wives of farmer pesticide applicators in the Agricultural Health StudyEllen F Kirrane
Coda Inc, Durham, North Carolina, USA
J Occup Environ Med 46:856-65. 2004..Farm women reporting the heaviest pesticide use could exacerbate their exposure by engaging in practices that could increase pesticide contact...
Farmworker exposure to pesticides: methodologic issues for the collection of comparable dataThomas A Arcury
Department of Family and Community Medicine, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157 1084, USA
Environ Health Perspect 114:923-8. 2006....
The biobank of the Norwegian Mother and Child Cohort Study: a resource for the next 100 yearsKjersti S Rønningen
Division of Epidemiology, Norwegian Institute of Public Health, 4404 Nydalen, N 0403 Oslo, Norway
Eur J Epidemiol 21:619-25. 2006..In designing specimen repositories, efforts need to balance future needs for samples with logistical constraints necessary to process and store samples in a timely fashion...
Depression and pesticide exposures in female spouses of licensed pesticide applicators in the agricultural health study cohortCheryl Beseler
Colorado Injury Control Research Center, Department of Psychology, Colorado State University, Fort Collins, Colorado 80523, USA
J Occup Environ Med 48:1005-13. 2006..26; 95% confidence interval [CI] = 1.72-6.19) but not low (OR = 1.09; CI = 0.91-1.31) or high (OR = 1.09; 95% CI = 0.91-1.31) cumulative pesticide exposure. CONCLUSION: Pesticide poisoning may contribute to risk of depression...
Reporting pesticide assessment results to farmworker families: development, implementation, and evaluation of a risk communication strategySara A Quandt
Department of Public Health Sciences, Piedmont Plaza II, Wake Forest University School of Medicine, Winston Salem, NC 27157 1063, USA
Environ Health Perspect 112:636-42. 2004..We review the strengths and weaknesses of such an approach and suggest areas for future research in risk communication to communities affected by environmental health risks...
Prevalence of exposure to solvents, metals, grain dust, and other hazards among farmers in the Agricultural Health StudyJoseph Coble
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Occupational Epidemiology Branch, 6120 Executive Boulevard, EPS8110, Rockville, Maryland 20892 7240, USA
J Expo Anal Environ Epidemiol 12:418-26. 2002..Confounding risk ratios calculated for these activities suggest that the magnitude of bias due to confounding is likely to be minimal...
Cancer risk and parental pesticide application in children of Agricultural Health Study participantsKori B Flower
Robert Wood Johnson Clinical Scholars Program and Division of Community Pediatrics, Department of Pediatrics, School of Public Health, University of North Carolina, Chapel Hill, NC 27599 7105, USA
Environ Health Perspect 112:631-5. 2004..Identification of excess lymphoma risk suggests that farm exposures including pesticides may play a role in the etiology of childhood lymphoma...
Mortality among pesticide applicators exposed to chlorpyrifos in the Agricultural Health StudyWon Jin Lee
Department of Preventive Medicine, College of Medicine, Korea University, Seoul, Korea
Environ Health Perspect 115:528-34. 2007..Chlorpyrifos is one of the most widely used organophosphate insecticides in the United States. Although the toxicity of chlorpyrifos has been extensively studied in animals, the epidemiologic data are limited...
Agricultural and residential pesticides in wipe samples from farmworker family residences in North Carolina and VirginiaSara A Quandt
Department of Public Health Sciences, Wake Forest University School of Medicine, Medical Center Boulevard, Piedmont Plaza II, Suite 512, Winston Salem, NC 27157 1063, USA
Environ Health Perspect 112:382-7. 2004..Although the likelihood of agricultural pesticide exposure has been considered high for farmworker families, these results indicate that residential pesticide use and exposure in this population merit further study...
