Y Honse

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint A site in the fourth membrane-associated domain of the N-methyl-D-aspartate receptor regulates desensitization and ion channel gating
    Hong Ren
    Unit on Cellular Neuropharmacology, Laboratory of Molecular and Cellular Neurobiology, National Institute on Alcohol Abuse and Alcoholism, Bethesda, Maryland 20892 8115, USA
    J Biol Chem 278:276-83. 2003
  2. ncbi request reprint A site of alcohol action in the fourth membrane-associated domain of the N-methyl-D-aspartate receptor
    Hong Ren
    Unit on Cellular Neuropharmacology, Laboratory of Molecular and Cellular Neurobiology, National Institute on Alcohol Abuse and Alcoholism, Bethesda, Maryland 20892 8205, USA
    J Biol Chem 278:48815-20. 2003
  3. ncbi request reprint Sites in the fourth membrane-associated domain regulate alcohol sensitivity of the NMDA receptor
    Yumiko Honse
    Unit on Cellular Neuropharmacology, Laboratory of Molecular and Cellular Neurobiology and Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892 8115, USA
    Neuropharmacology 46:647-54. 2004
  4. ncbi request reprint Cell surface expression of NR1 splice variants and NR2 subunits is modified by prenatal ethanol exposure
    Y Honse
    Division of Pharmacology and Toxicology, College of Pharmacy and Waggoner Center for Alcohol and Addiction Research, The University of Texas at Austin, Austin, TX 78712, USA
    Neuroscience 122:689-98. 2003
  5. ncbi request reprint Prenatal ethanol exposure modifies [3H]MK-801 binding to NMDA receptors: spermidine and ifenprodil
    Yumiko Honse
    Division of Pharmacology and Toxicology, College of Pharmacy and Waggoner Center for Alcohol and Addiction Research, The University of Texas at Austin, USA
    Alcohol Clin Exp Res 27:1993-2001. 2003
  6. ncbi request reprint Alternative modalities of adenovirus-mediated gene expression in hippocampal neurons cultured on microisland substrate
    Huanmian Chen
    Laboratory of Molecular Physiology, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Park Bldg Room 150, 12420 Parklawn Drive, MSC 8115, Bethesda, MD 20892 8815, USA
    Neurosci Lett 368:221-5. 2004
  7. ncbi request reprint CaMKIIalpha enhances the desensitization of NR2B-containing NMDA receptors by an autophosphorylation-dependent mechanism
    Suzanne Sessoms-Sikes
    Department of Molecular Physiology and Biophysics, The Center for Molecular Neuroscience, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    Mol Cell Neurosci 29:139-47. 2005
  8. ncbi request reprint Activation of NR2A-containing NMDA receptors is not obligatory for NMDA receptor-dependent long-term potentiation
    Carl Weitlauf
    Center for Molecular Neuroscience, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 0615, USA
    J Neurosci 25:8386-90. 2005

Collaborators

Detail Information

Publications8

  1. ncbi request reprint A site in the fourth membrane-associated domain of the N-methyl-D-aspartate receptor regulates desensitization and ion channel gating
    Hong Ren
    Unit on Cellular Neuropharmacology, Laboratory of Molecular and Cellular Neurobiology, National Institute on Alcohol Abuse and Alcoholism, Bethesda, Maryland 20892 8115, USA
    J Biol Chem 278:276-83. 2003
    ..These results demonstrate an important role for hydrophobic interactions at Met(823) in regulation of NMDA receptor function...
  2. ncbi request reprint A site of alcohol action in the fourth membrane-associated domain of the N-methyl-D-aspartate receptor
    Hong Ren
    Unit on Cellular Neuropharmacology, Laboratory of Molecular and Cellular Neurobiology, National Institute on Alcohol Abuse and Alcoholism, Bethesda, Maryland 20892 8205, USA
    J Biol Chem 278:48815-20. 2003
    ....
  3. ncbi request reprint Sites in the fourth membrane-associated domain regulate alcohol sensitivity of the NMDA receptor
    Yumiko Honse
    Unit on Cellular Neuropharmacology, Laboratory of Molecular and Cellular Neurobiology and Laboratory of Neurogenetics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892 8115, USA
    Neuropharmacology 46:647-54. 2004
    ..The changes in mean open time did not appear to be able to account for the observed differences in ethanol sensitivity. These results indicate that this region in M4 of the NR2A subunit may be involved in the action of alcohol...
  4. ncbi request reprint Cell surface expression of NR1 splice variants and NR2 subunits is modified by prenatal ethanol exposure
    Y Honse
    Division of Pharmacology and Toxicology, College of Pharmacy and Waggoner Center for Alcohol and Addiction Research, The University of Texas at Austin, Austin, TX 78712, USA
    Neuroscience 122:689-98. 2003
    ..Thus, these results suggest that prenatal exposure to ethanol may influence neuronal function by selective regulation of expression of C2'-terminal variants and NR2A subunits at the cell surface...
  5. ncbi request reprint Prenatal ethanol exposure modifies [3H]MK-801 binding to NMDA receptors: spermidine and ifenprodil
    Yumiko Honse
    Division of Pharmacology and Toxicology, College of Pharmacy and Waggoner Center for Alcohol and Addiction Research, The University of Texas at Austin, USA
    Alcohol Clin Exp Res 27:1993-2001. 2003
    ..Thus, the focus of the present study was to examine whether prenatal ethanol modifies native NMDA receptor levels...
  6. ncbi request reprint Alternative modalities of adenovirus-mediated gene expression in hippocampal neurons cultured on microisland substrate
    Huanmian Chen
    Laboratory of Molecular Physiology, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Park Bldg Room 150, 12420 Parklawn Drive, MSC 8115, Bethesda, MD 20892 8815, USA
    Neurosci Lett 368:221-5. 2004
    ..The advantages of the simplified procedure are greatly reduced preparation time and reduced requirements for equipment and expertise...
  7. ncbi request reprint CaMKIIalpha enhances the desensitization of NR2B-containing NMDA receptors by an autophosphorylation-dependent mechanism
    Suzanne Sessoms-Sikes
    Department of Molecular Physiology and Biophysics, The Center for Molecular Neuroscience, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    Mol Cell Neurosci 29:139-47. 2005
    ..These data suggest a novel mechanism for Ca2+-dependent negative-feedback regulation of NR2B-containing NMDARs in a CaMKII activity- and autophosphorylation-dependent manner that may modulate NMDAR-mediated synaptic plasticity...
  8. ncbi request reprint Activation of NR2A-containing NMDA receptors is not obligatory for NMDA receptor-dependent long-term potentiation
    Carl Weitlauf
    Center for Molecular Neuroscience, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 0615, USA
    J Neurosci 25:8386-90. 2005
    ..Furthermore, our data demonstrate that care must be exercised in the interpretation of data generated with AAM077 when the compound is applied before an agonist...