Thomas Hoenen

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc A novel Ebola virus expressing luciferase allows for rapid and quantitative testing of antivirals
    Thomas Hoenen
    Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA Electronic address
    Antiviral Res 99:207-13. 2013
  2. pmc Current ebola vaccines
    Thomas Hoenen
    National Institute of Allergy and Infectious Diseases, National Institutes of Health, Division of Intramural Research, Rocky Mountain Laboratories, Disease Modelling and Transmission Unit Laboratory of Virology, 2A120A, 903 S 4th St, Hamilton, MT, USA
    Expert Opin Biol Ther 12:859-72. 2012
  3. pmc Inclusion bodies are a site of ebolavirus replication
    Thomas Hoenen
    Laboratory for Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, Montana, USA
    J Virol 86:11779-88. 2012
  4. pmc The Ebola virus glycoprotein contributes to but is not sufficient for virulence in vivo
    Allison Groseth
    Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, USA
    PLoS Pathog 8:e1002847. 2012
  5. pmc Development and application of reporter-expressing mononegaviruses: current challenges and perspectives
    Darryl Falzarano
    Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA
    Antiviral Res 103:78-87. 2014
  6. pmc Ebola virus RNA editing depends on the primary editing site sequence and an upstream secondary structure
    Masfique Mehedi
    Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada Laboratory of Virology, Rocky Mountain Laboratories, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America
    PLoS Pathog 9:e1003677. 2013
  7. pmc Minigenomes, transcription and replication competent virus-like particles and beyond: reverse genetics systems for filoviruses and other negative stranded hemorrhagic fever viruses
    Thomas Hoenen
    Laboratory of Virology, Rocky Mountain Laboratories, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA Department of Virology, Philipps University Marburg, Marburg, Germany
    Antiviral Res 91:195-208. 2011

Collaborators

Detail Information

Publications7

  1. pmc A novel Ebola virus expressing luciferase allows for rapid and quantitative testing of antivirals
    Thomas Hoenen
    Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA Electronic address
    Antiviral Res 99:207-13. 2013
    ..The availability of this recombinant virus will allow for more rapid and quantitative evaluation of antivirals against EBOV, as well as the study of details of the EBOV life cycle...
  2. pmc Current ebola vaccines
    Thomas Hoenen
    National Institute of Allergy and Infectious Diseases, National Institutes of Health, Division of Intramural Research, Rocky Mountain Laboratories, Disease Modelling and Transmission Unit Laboratory of Virology, 2A120A, 903 S 4th St, Hamilton, MT, USA
    Expert Opin Biol Ther 12:859-72. 2012
    ..However, a number of vaccine candidates have been developed in the last decade that are highly protective in NHPs, the gold standard animal model for ebola hemorrhagic fever...
  3. pmc Inclusion bodies are a site of ebolavirus replication
    Thomas Hoenen
    Laboratory for Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rocky Mountain Laboratories, Hamilton, Montana, USA
    J Virol 86:11779-88. 2012
    ..Based on these data we conclude that, rather than being inert aggregates of nucleocapsids, ebolavirus inclusion bodies are in fact complex and dynamic structures and an important site at which viral RNA replication takes place...
  4. pmc The Ebola virus glycoprotein contributes to but is not sufficient for virulence in vivo
    Allison Groseth
    Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, USA
    PLoS Pathog 8:e1002847. 2012
    ..Thus, while these findings provide direct evidence that GP contributes to filovirus virulence in vivo, they also clearly indicate that other factors are needed for the acquisition of full virulence...
  5. pmc Development and application of reporter-expressing mononegaviruses: current challenges and perspectives
    Darryl Falzarano
    Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA
    Antiviral Res 103:78-87. 2014
    ....
  6. pmc Ebola virus RNA editing depends on the primary editing site sequence and an upstream secondary structure
    Masfique Mehedi
    Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada Laboratory of Virology, Rocky Mountain Laboratories, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America
    PLoS Pathog 9:e1003677. 2013
    ..Overall, our results provide novel insights into the RNA editing mechanism of EBOV, further understanding of which might result in novel intervention strategies against this viral pathogen. ..
  7. pmc Minigenomes, transcription and replication competent virus-like particles and beyond: reverse genetics systems for filoviruses and other negative stranded hemorrhagic fever viruses
    Thomas Hoenen
    Laboratory of Virology, Rocky Mountain Laboratories, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT, USA Department of Virology, Philipps University Marburg, Marburg, Germany
    Antiviral Res 91:195-208. 2011
    ....