A Hildesheim

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Cytokine and immunoglobulin concentrations in cervical secretions: reproducibility of the Weck-cel collection instrument and correlates of immune measures
    A Hildesheim
    Interdisciplinary Studies Section, Environmental Epidemiology Branch, DCEG, National Cancer Institute, Bethesda, MD 20892 7374, USA
    J Immunol Methods 225:131-43. 1999
  2. ncbi request reprint CYP2E1 genetic polymorphisms and risk of nasopharyngeal carcinoma in Taiwan
    A Hildesheim
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
    J Natl Cancer Inst 89:1207-12. 1997
  3. ncbi request reprint Immune activation in cervical neoplasia: cross-sectional association between plasma soluble interleukin 2 receptor levels and disease
    A Hildesheim
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892, USA
    Cancer Epidemiol Biomarkers Prev 6:807-13. 1997
  4. ncbi request reprint Human papillomavirus type 16 and risk of preinvasive and invasive vulvar cancer: results from a seroepidemiological case-control study
    A Hildesheim
    Environmental Epidemiology Branch, National Cancer Institute, Bethesda, Maryland 20892 7374, USA
    Obstet Gynecol 90:748-54. 1997
  5. pmc Collection of cervical secretions does not adversely affect Pap smears taken immediately afterward
    A Hildesheim
    Interdisciplinary Studies Section, Environmental Epidemiology Branch, National Cancer Institute, Bethesda, Maryland 20892 7374, USA
    Clin Diagn Lab Immunol 5:491-3. 1998
  6. ncbi request reprint Human leukocyte antigen class I/II alleles and development of human papillomavirus-related cervical neoplasia: results from a case-control study conducted in the United States
    A Hildesheim
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892 7374, USA
    Cancer Epidemiol Biomarkers Prev 7:1035-41. 1998
  7. ncbi request reprint Oral contraceptives as risk factors for cervical adenocarcinomas and squamous cell carcinomas
    J V Lacey
    National Cancer Institute, Bethesda, Maryland 20852 7234, USA
    Cancer Epidemiol Biomarkers Prev 8:1079-85. 1999
  8. pmc HPV co-factors related to the development of cervical cancer: results from a population-based study in Costa Rica
    A Hildesheim
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
    Br J Cancer 84:1219-26. 2001
  9. pmc Seroprevalence of human papillomavirus-16, -18, -31, and -45 in a population-based cohort of 10000 women in Costa Rica
    S S Wang
    National Cancer Institute, Bethesda, MD 20892 7234, USA
    Br J Cancer 89:1248-54. 2003
  10. pmc Determinants of human papillomavirus 16 serological conversion and persistence in a population-based cohort of 10 000 women in Costa Rica
    S S Wang
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7234, USA
    Br J Cancer 91:1269-74. 2004

Detail Information

Publications29

  1. ncbi request reprint Cytokine and immunoglobulin concentrations in cervical secretions: reproducibility of the Weck-cel collection instrument and correlates of immune measures
    A Hildesheim
    Interdisciplinary Studies Section, Environmental Epidemiology Branch, DCEG, National Cancer Institute, Bethesda, MD 20892 7374, USA
    J Immunol Methods 225:131-43. 1999
    ..In addition, various correlates of cytokine and immunoglobulin concentrations were identified...
  2. ncbi request reprint CYP2E1 genetic polymorphisms and risk of nasopharyngeal carcinoma in Taiwan
    A Hildesheim
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
    J Natl Cancer Inst 89:1207-12. 1997
    ..We conducted a case-control study to investigate whether such variations affect the risk of developing nasopharyngeal cancer...
  3. ncbi request reprint Immune activation in cervical neoplasia: cross-sectional association between plasma soluble interleukin 2 receptor levels and disease
    A Hildesheim
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892, USA
    Cancer Epidemiol Biomarkers Prev 6:807-13. 1997
    ..Also, future efforts should be aimed at determining whether the associations observed are causally related to disease progression or an effect of the disease...
  4. ncbi request reprint Human papillomavirus type 16 and risk of preinvasive and invasive vulvar cancer: results from a seroepidemiological case-control study
    A Hildesheim
    Environmental Epidemiology Branch, National Cancer Institute, Bethesda, Maryland 20892 7374, USA
    Obstet Gynecol 90:748-54. 1997
    ..To examine whether human papillomavirus (HPV) type 16 is involved in the etiology of vulvar carcinomas...
  5. pmc Collection of cervical secretions does not adversely affect Pap smears taken immediately afterward
    A Hildesheim
    Interdisciplinary Studies Section, Environmental Epidemiology Branch, National Cancer Institute, Bethesda, Maryland 20892 7374, USA
    Clin Diagn Lab Immunol 5:491-3. 1998
    ..Results from the present study suggest that the collection of cervical secretions with Weck-cel sponges does not adversely impact the quality of subsequently obtained Pap smears...
  6. ncbi request reprint Human leukocyte antigen class I/II alleles and development of human papillomavirus-related cervical neoplasia: results from a case-control study conducted in the United States
    A Hildesheim
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892 7374, USA
    Cancer Epidemiol Biomarkers Prev 7:1035-41. 1998
    ....
  7. ncbi request reprint Oral contraceptives as risk factors for cervical adenocarcinomas and squamous cell carcinomas
    J V Lacey
    National Cancer Institute, Bethesda, Maryland 20852 7234, USA
    Cancer Epidemiol Biomarkers Prev 8:1079-85. 1999
    ....
  8. pmc HPV co-factors related to the development of cervical cancer: results from a population-based study in Costa Rica
    A Hildesheim
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
    Br J Cancer 84:1219-26. 2001
    ..Among HPV-positive women, multiparity and smoking are risk factors for HSIL/CA. Oral contraceptive use may be associated with HSIL/CA in subgroups of women...
  9. pmc Seroprevalence of human papillomavirus-16, -18, -31, and -45 in a population-based cohort of 10000 women in Costa Rica
    S S Wang
    National Cancer Institute, Bethesda, MD 20892 7234, USA
    Br J Cancer 89:1248-54. 2003
    ..DNA- and sero-positive women showed the highest risk for concurrent CIN3/cancer, followed by DNA-positive, sero-negative women...
  10. pmc Determinants of human papillomavirus 16 serological conversion and persistence in a population-based cohort of 10 000 women in Costa Rica
    S S Wang
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7234, USA
    Br J Cancer 91:1269-74. 2004
    ..Higher HPV-16 viral load at enrollment was associated with seroconversion, and higher antibody titres at enrollment were associated with seropersistence...
  11. ncbi request reprint HPV DNA testing in cervical cancer screening: results from women in a high-risk province of Costa Rica
    M Schiffman
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
    JAMA 283:87-93. 2000
    ..Human papillomaviruses (HPVs) are known to cause most cervical cancer worldwide, but the utility of HPV DNA testing in cervical cancer prevention has not been determined...
  12. pmc Long-term persistence of prevalently detected human papillomavirus infections in the absence of detectable cervical precancer and cancer
    Philip E Castle
    Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892 7234, USA
    J Infect Dis 203:814-22. 2011
    ..Detailed descriptions of long-term persistence of human papillomavirus (HPV) in the absence of cervical precancer are lacking...
  13. ncbi request reprint An association of cervical inflammation with high-grade cervical neoplasia in women infected with oncogenic human papillomavirus (HPV)
    P E Castle
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA
    Cancer Epidemiol Biomarkers Prev 10:1021-7. 2001
    ..90-4.1). The results of this study suggest that cervical inflammation may be associated with high-grade lesions and may be a cofactor for high-grade cervical lesions in women infected with oncogenic HPV...
  14. ncbi request reprint Human leukocyte antigen class I and II haplotypes and risk of cervical cancer
    J D Carreon
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
    Tissue Antigens 66:321-4. 2005
    ..No HLA haplotype was significantly associated with cervical neoplasia, suggesting that individual allele associations reported to date (e.g. HLA-DR*13) are not likely explained by underlying haplotypes...
  15. ncbi request reprint Associations between smoking and adenocarcinomas and squamous cell carcinomas of the uterine cervix (United States)
    J V Lacey
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20852 7234, USA
    Cancer Causes Control 12:153-61. 2001
    ..Few studies of smoking and cervical carcinoma have addressed the rare cervical adenocarcinomas or used DNA-based tests to control for human papillomavirus (HPV) infection...
  16. pmc A case-control study of endogenous hormones and cervical cancer
    T S Shields
    Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, 6120 Executive Blvd, MSC 7234, Rockville, MD 20852, USA
    Br J Cancer 90:146-52. 2004
    ..Nonetheless, our results do not support the hypothesis that plasma levels of sex hormones have an important bearing on the risk of cervical neoplasia in HPV-infected women...
  17. ncbi request reprint Occupational exposure to wood, formaldehyde, and solvents and risk of nasopharyngeal carcinoma
    A Hildesheim
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892, USA
    Cancer Epidemiol Biomarkers Prev 10:1145-53. 2001
    ..Formaldehyde exposure is less clearly linked to NPC, whereas exposure to solvents is unlikely to be involved in NPC pathogenesis...
  18. ncbi request reprint Human leukocyte antigen class I and II alleles and risk of cervical neoplasia: results from a population-based study in Costa Rica
    S S Wang
    Interdisciplinary Studies Section, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7234, USA
    J Infect Dis 184:1310-4. 2001
    ..2-23.7). These results support the hypothesis that multiple risk alleles are needed in order to increase risk for cervical neoplasia, but a single protective allele may be sufficient for protection...
  19. pmc Short term persistence of human papillomavirus and risk of cervical precancer and cancer: population based cohort study
    Philip E Castle
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, DHHS, Bethesda, MD 20892, USA
    BMJ 339:b2569. 2009
    ....
  20. ncbi request reprint A study on immunological responses to exposures encountered in corn farming
    R Vermeulen
    Division of Cancer Epidemiology and Genetics, NCI, Rockville, MD 20892, USA
    J Biochem Mol Toxicol 19:172. 2005
  21. ncbi request reprint Evaluation of self-collected cervicovaginal cell samples for human papillomavirus testing by polymerase chain reaction
    P E Gravitt
    Department of Human Genetics, Roche Molecular Systems, Alameda, California 94501, USA
    Cancer Epidemiol Biomarkers Prev 10:95-100. 2001
    ..We have demonstrated that a self-collected Dacron swab sample of cervicovaginal cells is a technically feasible alternative to clinician-administered cervical cell collection in natural history studies of HPV and cervical cancer...
  22. pmc Circulating levels of immune and inflammatory markers and long versus short survival in early-stage lung cancer
    C Bodelon
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20852, USA
    Ann Oncol 24:2073-9. 2013
    ..Associations between markers of inflammation and survival from lung cancer have been observed...
  23. pmc Correlates of anti-EBV EBNA1 IgA positivity among unaffected relatives from nasopharyngeal carcinoma multiplex families
    C M Chang
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, 6120 Executive Blvd, EPS 7073, Rockville, MD, USA
    Br J Cancer 106:206-9. 2012
    ....
  24. ncbi request reprint Barrier and spermicidal contraceptive methods and risk of invasive cervical cancer
    A Hildesheim
    Environmental Epidemiology Branch, National Cancer Institute, Bethesda, MD 20892
    Epidemiology 1:266-72. 1990
    ..The potential ability of spermicides to reduce cervical cancer risk by neutralizing viral agents warrants further attention...
  25. ncbi request reprint Clinical trial designs for the early clinical development of therapeutic cancer vaccines
    R M Simon
    Branch of Biometric Research, Biostatistics and Data Management Section, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 7434, USA
    J Clin Oncol 19:1848-54. 2001
    ..Several conclusions for expediting the clinical development of effective cancer vaccines are proposed...
  26. pmc A population based study of herpes simplex virus 2 seroprevalence in rural Costa Rica
    A C Rodriguez
    Guanacaste Project, Costa Rica Foundation for Health Sciences, San Jose, Costa Rica
    Sex Transm Infect 79:460-5. 2003
    ....
  27. ncbi request reprint Safety and immunogenicity trial in adult volunteers of a human papillomavirus 16 L1 virus-like particle vaccine
    C D Harro
    Center for Immunization Research, Department of International Medicine, School of Hygiene and Public Health, The Johns Hopkins University, Baltimore, MD, USA
    J Natl Cancer Inst 93:284-92. 2001
    ....
  28. ncbi request reprint Metabolic gene polymorphism frequencies in control populations
    S Garte
    Environmental and Occupational Health Sciences Institute, University of Medicine and Dentistry of New Jersey, Piscataway, New Jersey 08854, USA
    Cancer Epidemiol Biomarkers Prev 10:1239-48. 2001
    ..No examples of linkage disequilibrium between the different loci were detected based on comparison of observed and expected frequencies for combinations of specific alleles...
  29. pmc An infrequent point mutation of the p53 gene in human nasopharyngeal carcinoma
    Y Sun
    Program Resources Incorporated DynCorp, Frederick, MD
    Proc Natl Acad Sci U S A 89:6516-20. 1992
    ..This result contrasts with the relatively high frequency of p53 mutations associated with several other human carcinomas and suggests the importance of other genes in NPC genesis...