J R Hibbeln

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Increasing homicide rates and linoleic acid consumption among five Western countries, 1961-2000
    Joseph R Hibbeln
    Laboratory of Membrane Biochemistry and Biophysics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland 20892, USA
    Lipids 39:1207-13. 2004
  2. ncbi request reprint The relationship between folate and docosahexaenoic acid in men
    J C Umhau
    Laboratory of Clinical Studies, National Institute on Alcohol Abuse and Alcoholism NIAAA, National Institutes of Health, MD 20892 1108, USA
    Eur J Clin Nutr 60:352-7. 2006
  3. ncbi request reprint Omega-3 fatty acid deficiencies in neurodevelopment, aggression and autonomic dysregulation: opportunities for intervention
    Joseph R Hibbeln
    National Institute on Alcohol Abuse and Alcoholism, Bethesda, 20892, USA
    Int Rev Psychiatry 18:107-18. 2006
  4. ncbi request reprint Relationship between omega-3 fatty acids and plasma neuroactive steroids in alcoholism, depression and controls
    L R G Nieminen
    National Institutes of Health, National Institutes on Alcoholism and Alcohol Abuse, Laboratory of Membrane Biophysics and Biochemistry, Bethesda, MD 20814, USA
    Prostaglandins Leukot Essent Fatty Acids 75:309-14. 2006
  5. ncbi request reprint Seafood consumption, the DHA content of mothers' milk and prevalence rates of postpartum depression: a cross-national, ecological analysis
    Joseph R Hibbeln
    Laboratory of Membrane Biophysics and Biochemistry, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Park 5, Room 150, 12420 Parklawn Drive, Rockville, MD 20892, USA
    J Affect Disord 69:15-29. 2002
  6. ncbi request reprint Cultural symbolism of fish and the psychotropic properties of omega-3 fatty acids
    L C Reis
    Section on Nutritional Neuroscience, Laboratory of Membrane Biophysics and Biochemistry, National Institute on Alcohol Abuse and Alcoholism, NIH, Rockville, MD, USA
    Prostaglandins Leukot Essent Fatty Acids 75:227-36. 2006
  7. ncbi request reprint A placebo-controlled trial of omega-3 fatty acid (ethyl eicosapentaenoic acid) supplementation for residual symptoms and cognitive impairment in schizophrenia
    W S Fenton
    NIMH, NIH, Bethesda, MD 20892 9621, USA
    Am J Psychiatry 158:2071-4. 2001
  8. ncbi request reprint Maternal seafood consumption in pregnancy and neurodevelopmental outcomes in childhood (ALSPAC study): an observational cohort study
    Joseph R Hibbeln
    Laboratory of Membrane Biophysics and Biochemistry, US National Institute on Alcohol Abuse and Alcoholism, US National Institutes of Health, Bethesda, MD 20952, USA
    Lancet 369:578-85. 2007
  9. ncbi request reprint Serum omega-3 fatty acids are associated with variation in mood, personality and behavior in hypercholesterolemic community volunteers
    Sarah M Conklin
    Cardiovascular Behavioral Medicine Postdoctoral Training Program, Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15260, United States
    Psychiatry Res 152:1-10. 2007
  10. ncbi request reprint High omega-6 and low omega-3 fatty acids are associated with depressive symptoms and neuroticism
    Sarah M Conklin
    Department of Psychology, Allegheny College, 520 North Main Street, Meadville, PA 16335 3902, USA
    Psychosom Med 69:932-4. 2007

Detail Information

Publications29

  1. ncbi request reprint Increasing homicide rates and linoleic acid consumption among five Western countries, 1961-2000
    Joseph R Hibbeln
    Laboratory of Membrane Biochemistry and Biophysics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, Maryland 20892, USA
    Lipids 39:1207-13. 2004
    ..Low linoleate diets may prevent behavioral maladies that correctional institutions, social service programs, and mental health providers intend to treat...
  2. ncbi request reprint The relationship between folate and docosahexaenoic acid in men
    J C Umhau
    Laboratory of Clinical Studies, National Institute on Alcohol Abuse and Alcoholism NIAAA, National Institutes of Health, MD 20892 1108, USA
    Eur J Clin Nutr 60:352-7. 2006
    ..The objective of this study is to determine if the blood concentrations of folate and DHA are correlated in humans...
  3. ncbi request reprint Omega-3 fatty acid deficiencies in neurodevelopment, aggression and autonomic dysregulation: opportunities for intervention
    Joseph R Hibbeln
    National Institute on Alcohol Abuse and Alcoholism, Bethesda, 20892, USA
    Int Rev Psychiatry 18:107-18. 2006
    ..Ensuring optimal intakes of omega-3 fatty acids during early development and adulthood shows considerable promise in preventing aggression and hostility...
  4. ncbi request reprint Relationship between omega-3 fatty acids and plasma neuroactive steroids in alcoholism, depression and controls
    L R G Nieminen
    National Institutes of Health, National Institutes on Alcoholism and Alcohol Abuse, Laboratory of Membrane Biophysics and Biochemistry, Bethesda, MD 20814, USA
    Prostaglandins Leukot Essent Fatty Acids 75:309-14. 2006
    ..55, P < 0.05). In this pilot observational study, lower long-chain omega-3 essential fatty acid status was associated with higher neuroactive steroid concentrations, possibly indicating increased feedback inhibition of the HPA axis...
  5. ncbi request reprint Seafood consumption, the DHA content of mothers' milk and prevalence rates of postpartum depression: a cross-national, ecological analysis
    Joseph R Hibbeln
    Laboratory of Membrane Biophysics and Biochemistry, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Park 5, Room 150, 12420 Parklawn Drive, Rockville, MD 20892, USA
    J Affect Disord 69:15-29. 2002
    ..We postulated that the DHA content of mothers' milk and seafood consumption would both predict prevalence rates of postpartum depression across countries...
  6. ncbi request reprint Cultural symbolism of fish and the psychotropic properties of omega-3 fatty acids
    L C Reis
    Section on Nutritional Neuroscience, Laboratory of Membrane Biophysics and Biochemistry, National Institute on Alcohol Abuse and Alcoholism, NIH, Rockville, MD, USA
    Prostaglandins Leukot Essent Fatty Acids 75:227-36. 2006
    ..This understanding of the perception of fish as a symbolically healing or purifying food can assist current messages improving public health...
  7. ncbi request reprint A placebo-controlled trial of omega-3 fatty acid (ethyl eicosapentaenoic acid) supplementation for residual symptoms and cognitive impairment in schizophrenia
    W S Fenton
    NIMH, NIH, Bethesda, MD 20892 9621, USA
    Am J Psychiatry 158:2071-4. 2001
    ..This study determined if augmentation of neuroleptics with 3 g/day of ethyl eicosapentaenoic acid (EPA) improves symptoms and cognition in patients with schizophrenia or schizoaffective disorder...
  8. ncbi request reprint Maternal seafood consumption in pregnancy and neurodevelopmental outcomes in childhood (ALSPAC study): an observational cohort study
    Joseph R Hibbeln
    Laboratory of Membrane Biophysics and Biochemistry, US National Institute on Alcohol Abuse and Alcoholism, US National Institutes of Health, Bethesda, MD 20952, USA
    Lancet 369:578-85. 2007
    ..We used the Avon Longitudinal Study of Parents and Children (ALSPAC) to assess the possible benefits and hazards to a child's development of different levels of maternal seafood intake during pregnancy...
  9. ncbi request reprint Serum omega-3 fatty acids are associated with variation in mood, personality and behavior in hypercholesterolemic community volunteers
    Sarah M Conklin
    Cardiovascular Behavioral Medicine Postdoctoral Training Program, Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15260, United States
    Psychiatry Res 152:1-10. 2007
    ..These findings suggest that omega-3 fatty acid status is associated with variability in affect regulation, personality and impulse control...
  10. ncbi request reprint High omega-6 and low omega-3 fatty acids are associated with depressive symptoms and neuroticism
    Sarah M Conklin
    Department of Psychology, Allegheny College, 520 North Main Street, Meadville, PA 16335 3902, USA
    Psychosom Med 69:932-4. 2007
    ..Previously we reported that the relative concentrations of omega-3 and omega-6 polyunsaturated fatty acids in serum covary with depressive symptomatology and neuroticism in hypercholesterolemic adults...
  11. ncbi request reprint Healthy intakes of n-3 and n-6 fatty acids: estimations considering worldwide diversity
    Joseph R Hibbeln
    Laboratory of Membrane Biochemistry and Biophysics and the National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892 2088, USA
    Am J Clin Nutr 83:1483S-1493S. 2006
    ....
  12. pmc Associations between increases in plasma n-3 polyunsaturated fatty acids following supplementation and decreases in anger and anxiety in substance abusers
    Laure Buydens-Branchey
    Psychiatry Service, DVA New York Harbor Healthcare System, Brooklyn, NY 11209, USA
    Prog Neuropsychopharmacol Biol Psychiatry 32:568-75. 2008
    ....
  13. ncbi request reprint Omega-3 polyunsaturated essential fatty acid status as a predictor of future suicide risk
    M Elizabeth Sublette
    Department of Neuroscience, NY State Psychiatric Institute, Columbia University, Unit 42, 1051 Riverside Dr, New York, NY 10032, USA
    Am J Psychiatry 163:1100-2. 2006
    ..Predicting risk of future suicidal behaviors by essential fatty acid status merits examination...
  14. ncbi request reprint Compartmental analyses of plasma n-3 essential fatty acids among male and female smokers and nonsmokers
    Robert J Pawlosky
    Laboratory of Metabolic Control, National Institutes on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA
    J Lipid Res 48:935-43. 2007
    ..03) that was greater compared with nonsmokers. Smoking increased the bioavailability of n-3 FAs from plasma, accelerated the fractional synthetic rates, and heightened the percent formation of some long-chain n-3 PUFAs in men and women...
  15. ncbi request reprint From homicide to happiness--a commentary on omega-3 fatty acids in human society. Cleave Award Lecture
    Joseph R Hibbeln
    Section on Nutritional Neurosciences, Laboratory of Membrane Biochenmistr and Biophysics, National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD 20892 2088, USA
    Nutr Health 19:9-19. 2007
    ....
  16. ncbi request reprint Omega-3 status and cerebrospinal fluid corticotrophin releasing hormone in perpetrators of domestic violence
    Joseph R Hibbeln
    Laboratory of Membrane Biophysics and Biochemistry, National Institute on Alcohol Abuse and Alcoholism, NIH, Rockville, MD 20852, USA
    Biol Psychiatry 56:895-7. 2004
    ..Prostaglandins E2 and F2alpha, which increase corticotrophin-releasing hormone RNA expression in this pathway, are reduced by dietary intakes of omega-3 fats...
  17. ncbi request reprint Fatty acid formula supplementation and neuromotor development in rhesus monkey neonates
    Maribeth Champoux
    Laboratory of Comparative Ethology, NICHD, Poolesville, Maryland 20837, USA
    Pediatr Res 51:273-81. 2002
    ..Supplementation did not affect measures of activity or state control, indicating no effect on temperament. These data support the assertion that preformed DHA and arachidonic acid in infant formulas are required for optimal development...
  18. ncbi request reprint Polyunsaturated fatty acid status and relapse vulnerability in cocaine addicts
    Laure Buydens-Branchey
    Department of Psychiatry, State University of New York Health Science Center at Brooklyn and Veterans Affairs New York Harbor Healthcare System, Brooklyn Campus 11S BK, 800 Poly Place, Brooklyn, NY 11209, USA
    Psychiatry Res 120:29-35. 2003
    ....
  19. ncbi request reprint Visual acuity and retinal function in infant monkeys fed long-chain PUFA
    Brett G Jeffrey
    Department of Paediatrics and Child Health, Flinders Medical Centre, The Flinders University of South Australia, Bedford Park, Adelaide, SA 5042, Australia
    Lipids 37:839-48. 2002
    ..The results suggest that supplementation of the infant monkey diet with 1.0% DHA and 1.0% AA neither harms nor provides substantial benefit to the development of visual acuity or retinal function in the first four postnatal months...
  20. ncbi request reprint Effects of beef- and fish-based diets on the kinetics of n-3 fatty acid metabolism in human subjects
    Robert J Pawlosky
    Food Composition Laboratory, Beltsville Human Nutrition Research Center, US Department of Agriculture, Beltsville, MD, USA
    Am J Clin Nutr 77:565-72. 2003
    ..Diets rich in 20- and 22-carbon PUFAs may inhibit desaturase expression or activity and decrease the synthesis of long-chain unsaturated fatty acids...
  21. ncbi request reprint Smoking, gender, and dietary influences on erythrocyte essential fatty acid composition among patients with schizophrenia or schizoaffective disorder
    Joseph R Hibbeln
    Laboratory of Membrane Biochemistry and Biophysics, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Rockville, Maryland 20852, USA
    Biol Psychiatry 53:431-41. 2003
    ....
  22. doi request reprint Omega-3 fatty acids and supportive psychotherapy for perinatal depression: a randomized placebo-controlled study
    Marlene P Freeman
    Women s Mental Health Center, University of Texas Southwestern Medical Center, Dallas TX, USA
    J Affect Disord 110:142-8. 2008
    ..This study was designed to investigate the feasibility, safety, and efficacy of omega-3 fatty acids for perinatal depression in addition to supportive psychotherapy...
  23. ncbi request reprint Omega-3 fatty acid supplementation in patients with recurrent self-harm. Single-centre double-blind randomised controlled trial
    Brian Hallahan
    Department of Psychiatry, Beaumont Hospital and The Royal College of Surgeons in Ireland, Ireland
    Br J Psychiatry 190:118-22. 2007
    ..Trials have demonstrated benefits of long-chain omega-3 essential fatty acid (n-3 EFA) supplementation in a variety of psychiatric disorders...
  24. ncbi request reprint Lipids and essential fatty acids in patients presenting with self-harm
    Malcolm R Garland
    Department of Adult Psychiatry, Galway University Hospital and the Clinical Sciences Institute, National University of Ireland, Ireland
    Br J Psychiatry 190:112-7. 2007
    ..Low cholesterol has been reliably demonstrated in people who self-harm...
  25. ncbi request reprint Polyunsaturated fatty acid status and aggression in cocaine addicts
    Laure Buydens-Branchey
    Department of Psychiatry, State University of New York Health Science Center at Brooklyn, Brooklyn, NY 11209, USA
    Drug Alcohol Depend 71:319-23. 2003
    ..We also explored the possibility that their FA levels would change after a 2 week stay on an inpatient unit where a standard diet would be provided...
  26. ncbi request reprint Omega-3 fatty acids: evidence basis for treatment and future research in psychiatry
    Marlene P Freeman
    Women s Mental Health Program, Department of Psychiatry, University of Arizona College of Medicine, Tucson 85724 5002, USA
    J Clin Psychiatry 67:1954-67. 2006
    ..To determine if the available data support the use of omega-3 essential fatty acids (EFA) for clinical use in the prevention and/or treatment of psychiatric disorders...
  27. ncbi request reprint Cross-national comparisons of seafood consumption and rates of bipolar disorders
    Simona Noaghiul
    New York State Psychiatric Institute, Columbia University College of Physicians and Surgeons, New York, USA
    Am J Psychiatry 160:2222-7. 2003
    ..The authors sought to determine if greater seafood consumption, a measure of omega-3 fatty acid intake, is associated with lower prevalence rates of bipolar disorder in community samples...
  28. ncbi request reprint Statin treatment alters serum n-3 and n-6 fatty acids in hypercholesterolemic patients
    Jennifer I Harris
    Department of Medicine, Center for Clinical Pharmacology, School of Medicine, University of Pittsburgh, 4015 O Hara Street, Old Engineering Hall, Room 506, Pittsburgh, PA 15260, USA
    Prostaglandins Leukot Essent Fatty Acids 71:263-9. 2004
    ..5 to 18.8 (P<.01), and tended to increase the AA:DHA ratio (P=.053). Thus, simvastatin lowered serum fatty acid concentrations while also altering the relative percentages of important PUFAs...
  29. ncbi request reprint The Lancet and the Royal Society are both right and wrong
    Michael A Crawford
    Lancet 366:714-5. 2005