Research Topics
Genomes and GenesSpecies | Sher L HendricksonSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
Mitochondrial DNA haplogroups influence lipoatrophy after highly active antiretroviral therapySher L Hendrickson
Laboratory of Genomic Diversity, National Cancer Institute, Frederick, MD 21702 1201
J Acquir Immune Defic Syndr 51:111-6. 2009..05, OR = 0.52, 95% CI = 0.20 to 1.00). These data suggest that mitochondrial DNA haplogroup may influence the propensity for lipoatrophy in patients receiving nucleoside reverse transcriptase inhibitors...- Effect of host genetics on incidence of HIV neuroretinal disorder in patients with AIDSEfe Sezgin
Laboratory of Genomic Diversity, National Cancer Institute, Frederick, MD 21702 1201, USA
J Acquir Immune Defic Syndr 54:343-51. 2010..Clearly, further studies are warrented... - Mitochondrial DNA haplogroups influence AIDS progressionSher L Hendrickson
Laboratory of Genomic Diversity, National Cancer Institute, Frederick, Maryland 21702 1201, USA
AIDS 22:2429-39. 2008.... - Effect of host genetics on the development of cytomegalovirus retinitis in patients with AIDSEfe Sezgin
Laboratory of Genomic Diversity, SAIC Frederick, National Cancer Institute, Frederick, Maryland 21702 1201, USA
J Infect Dis 202:606-13. 2010..The ubiquitous CMV pathogen contains a human interleukin-10 (IL-10) homolog in its genome and utilizes it to evade host immune reactions through an IL-10 receptor mediated immune-suppression pathway... - Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progressionSher L Hendrickson
Laboratory of Genomic Diversity, National Cancer Institute, Frederick, Maryland, USA
PLoS ONE 5:e12862. 2010..Mitochondrial pathogenesis occurs in HIV patients and genetically, mitochondrial DNA haplogroups with presumed functional differences have been associated with differential AIDS progression... - Genome-wide association study implicates PARD3B-based AIDS restrictionJennifer L Troyer
Laboratory of Genomic Diversity, SAIC Frederick, Inc, Frederick, MD 21702, USA
J Infect Dis 203:1491-502. 2011..Here we used clinically well-characterized subjects from 5 pretreatment HIV/AIDS cohorts for a genome-wide association study to identify gene associations with rate of AIDS progression... 
Mitochondrial haplogroups are associated with risk of neuroretinal disorder in HIV-positive patientsSher L Hendrickson
Laboratory of Genomic Diversity, National Cancer Institute, Frederick, MD 21702 1201, USA
J Acquir Immune Defic Syndr 53:451-5. 2010..5% vs. 8.9% in patients with vs. without haplogroup J, respectively, P = 0.05). These data suggest that mitochondrial genotype may influence propensity to develop HIV-associated NRD in patients with AIDS...- The principal genetic determinants for nasopharyngeal carcinoma in China involve the HLA class I antigen recognition grooveMinzhong Tang
College of Life Science and Bio engineering, Beijing University of Technology, Beijing, China
PLoS Genet 8:e1003103. 2012.... - Host genetic influences on highly active antiretroviral therapy efficacy and AIDS-free survivalSher L Hendrickson
Laboratory of Genomic Diversity, National Cancer Institute, Frederick, MD 21702 1201, USA
J Acquir Immune Defic Syndr 48:263-71. 2008..27; P=0.01). ARG influence after HAART suggests residual HIV-1 replication, and spread continues even in patients successfully suppressing detectable viral RNA... 
NPHS2 variation in sporadic focal segmental glomerulosclerosisLouise M McKenzie
Laboratory of Genomic Diversity, SAIC Frederick, National Cancer Institute, NCI Frederick, Frederick, Maryland, USA
J Am Soc Nephrol 18:2987-95. 2007..5, P = 0.001). These results indicate that genetic variation or mutation of NPHS2 may play a role in late-onset sporadic FSGS...