Research Topics
| Stephen J HeishmanSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
Determination of the reliability and validity of the Marijuana Craving Questionnaire using imagery scriptsEdward G Singleton
Division of Applied Psychology, University of Baltimore, Maryland, USA
Exp Clin Psychopharmacol 10:47-53. 2002..These results verify and extend the reliability and validity of the MCQ as a multidimensional measurement of marijuana craving. The data also suggest that drug craving is not an all-or-none phenomenon...
Reliability and validity of a Short Form of the Tobacco Craving QuestionnaireStephen J Heishman
Nicotine Psychopharmacology Unit, Clinical Pharmacology and Therapeutics Branch, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD 21224, USA
Nicotine Tob Res 10:643-51. 2008..Test-retest correlation coefficients were also similar to those found in a previous study. These findings suggest that the TCQ-SF is as valid and reliable as the 47-item TCQ in measuring tobacco craving...- Effect of tobacco craving cues on memory encoding and retrieval in smokersStephen J Heishman
Clinical Pharmacology and Therapeutics Branch, National Institute on Drug Abuse, NIH, DHHS, Intramural Research Program, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
Addict Behav 31:1116-21. 2006..There was a trend toward impaired working memory following craving scripts compared with neutral scripts. These data support the hypothesis that the cognitive underpinnings of encoding and retrieval processes are distinct... - Meta-analysis of the acute effects of nicotine and smoking on human performanceStephen J Heishman
Nicotine Psychopharmacology Section, National Institute on Drug Abuse, NIH Intramural Research Program, 251 Bayview Blvd, Baltimore, MD 21224, USA
Psychopharmacology (Berl) 210:453-69. 2010..Exp Clin Psychopharmacol 2:345-395, 1994) and to determine which aspects of human performance were most sensitive to the effects of nicotine and smoking... - Imagery-induced tobacco craving: duration and lack of assessment reactivity biasStephen J Heishman
National Institute on Drug Abuse, National Institutes of Health, Department of Health and Human Services, Baltimore, Maryland 21224, USA
Psychol Addict Behav 18:284-8. 2004..There was no evidence that TCQ responses were affected by repeated measurement. These data suggest that imagery-induced craving can persist for at least 15 min and that craving responses are not biased by assessment reactivity... - Reliability and validity of a short form of the Marijuana Craving QuestionnaireStephen J Heishman
Intramural Research Program, National Institute on Drug Abuse, 251 Bayview Blvd, Baltimore, MD 21224, USA
Drug Alcohol Depend 102:35-40. 2009..For use in research and clinical settings, we constructed a 12-item version of the MCQ by selecting three items from each of the four factors that exhibited the greatest within-factor internal consistency (Cronbach's alpha coefficient)... - Tobacco Craving Questionnaire: reliability and validity of a new multifactorial instrumentStephen J Heishman
Clinical Pharmacology and Therapeutics Branch, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore MD 21224, USA
Nicotine Tob Res 5:645-54. 2003..These preliminary data suggest that the TCQ is a reliable and valid instrument for assessing tobacco craving in individuals not attempting to reduce or quit smoking... - Prolonged duration of craving, mood, and autonomic responses elicited by cues and imagery in smokers: Effects of tobacco deprivation and sexStephen J Heishman
Nicotine Psychopharmacology Section, NIDA Intramural Research Program, 251 Bayview Boulevard, Suite 200, Baltimore, MD 21224, USA
Exp Clin Psychopharmacol 18:245-56. 2010..These findings provide new data on the time course, magnitude, and tobacco deprivation effects on elicited craving. Sex differences were dependent on stimulus type and deprivation condition... - Dose-related enhancement of mood and cognition in smokers administered nicotine nasal sprayCarol S Myers
Clinical Pharmacology and Therapeutics Branch, National Institute on Drug Abuse, NIH Intramural Research Program, Baltimore, MD 21224, USA
Neuropsychopharmacology 33:588-98. 2008..These results provide an unequivocal determination that nicotine enhanced attentional and computational abilities in nondeprived smokers and suggest these cognitive domains as substrates for novel therapeutic indications... - Perception of smoking risks and motivation to quit among nontreatment-seeking smokers with and without schizophreniaDeanna L Kelly
Maryland Psychiatric Research Center, University of Maryland, Baltimore School of Medicine, Box 21247, Baltimore, MD 21228, USA
Schizophr Bull 38:543-51. 2012.... - Quitting among non-treatment-seeking marijuana users: reasons and changes in other substance useMarc L Copersino
Clinical Pharmacology and Therapeutics Branch, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Department of Health and Human Services, Baltimore, Maryland, USA
Am J Addict 15:297-302. 2006..These findings suggest areas for further research on spontaneous recovery from marijuana use... - Sociodemographic characteristics of cannabis smokers and the experience of cannabis withdrawalMarc L Copersino
Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, Maryland, USA
Am J Drug Alcohol Abuse 36:311-9. 2010..Cannabis withdrawal can be a negative reinforcer for relapse, but little is known about its association with demographic characteristics... - Cannabis withdrawal symptoms in non-treatment-seeking adult cannabis smokersKenneth H Levin
Intramural Research Program, National Institute on Drug Abuse, Baltimore, MD 21224, USA
Drug Alcohol Depend 111:120-7. 2010..Cannabis withdrawal is not recognized in DSM-IV because of doubts about its clinical significance... - Single and multiple doses of rimonabant antagonize acute effects of smoked cannabis in male cannabis usersMarilyn A Huestis
Clinical Pharmacology and Therapeutics Research Branch, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD 21224, USA
Psychopharmacology (Berl) 194:505-15. 2007..A single 90-mg dose of the cannabinoid CB1 receptor antagonist rimonabant attenuates effects of smoked cannabis in humans... - Cannabis withdrawal among non-treatment-seeking adult cannabis usersMarc L Copersino
Clinical Pharmacology and Therapeutics Branch, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Department of Health and Human Services, Baltimore, Maryland 21224-6823, USA
Am J Addict 15:8-14. 2006.... - Tobacco craving in smokers with and without schizophreniaSuzanne Lo
Nicotine Psychopharmacology Section, National Institute on Drug Abuse, NIH Intramural Research Program, 251 Bayview Blvd, Baltimore, MD 21224, United States
Schizophr Res 127:241-5. 2011.... - Diagnostic criteria for cannabis withdrawal syndromeDavid A Gorelick
Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD 21224, USA
Drug Alcohol Depend 123:141-7. 2012..Cannabis withdrawal occurs in frequent users who quit, but there are no accepted diagnostic criteria for a cannabis withdrawal syndrome (CWS). This study evaluated diagnostic criteria for CWS proposed in DSM-V and two earlier proposals... - Oral fluid nicotine markers to assess smoking status and recency of useKarl B Scheidweiler
Chemistry and Drug Metabolism Section, Intramural Research Program, National Institute on Drug Abuse, Baltimore, MD, USA
Ther Drug Monit 33:609-18. 2011..Few studies, however, assessed nicotine markers in oral fluid other than cotinine; other markers might improve smoking status assessment and/or time of last cigarette... - Consistency of subjective responses to imagery-induced tobacco craving over multiple sessionsDustin C Lee
Clinical Pharmacology and Therapeutics Branch, National Institute on Drug Abuse, Intramural Research Program, NIH, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
Addict Behav 32:2130-9. 2007..These results have practical implications for examining individual differences in sensitivity to smoking cues and for studies involving repeated measurement of elicited craving over time... - Relative performance of common biochemical indicators in detecting cigarette smokingGina F Marrone
Nicotine Psychopharmacology Section, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD 21224, USA
Addiction 106:1325-34. 2011..We evaluated and compared the performance of breath CO and semiquantitative cotinine immunoassay test strips (urine and saliva NicAlert®) alone and in combination... - Illicit drug use in heavy smokers with and without schizophreniaKristen M Mackowick
Nicotine Psychopharmacology Section, Intramural Research Program, National Institute on Drug Abuse, 251 Bayview Boulevard, Baltimore, MD 21224, USA
Schizophr Res 139:194-200. 2012..During a 2-3-hour session, participants completed demographic and research questionnaires, including the Drug Use Survey (DUS)... 
Effects of moderate-dose treatment with varenicline on neurobiological and cognitive biomarkers in smokers and nonsmokers with schizophrenia or schizoaffective disorderL Elliot Hong
Maryland Psychiatric Research Center, Baltimore, MD 21228, USA
Arch Gen Psychiatry 68:1195-206. 2011..It is not yet clear which nicotinic acetylcholine receptor (nAChR) subtype or subtypes are responsible for these seemingly pervasive nicotinic effects in schizophrenia and schizoaffective disorder...- Interest in marijuana treatment programs among teenage smokers and nonsmokersAmy J Sheer
National Institute on Drug Abuse, Intramural Research Program, Baltimore, MD 21224, USA
J Subst Abuse Treat 37:421-5. 2009..These findings suggest that most adolescent marijuana smokers endorse the need for and are willing to attend marijuana treatment programs... - Puffing behavior during the smoking of a single cigarette in tobacco-dependent adolescentsCharles C Collins
Nicotine Psychopharmacology Section, Intramural Research Program, National Institute on Drug Abuse, 251 Bayview Boulevard, Baltimore, MD 21224, USA
Nicotine Tob Res 12:164-7. 2010..The purpose of this study was to examine the pattern of puffing behavior during the smoking of a single cigarette in adolescents... - The cannabinoid CB1 receptor antagonist rimonabant attenuates the hypotensive effect of smoked marijuana in male smokersDavid A Gorelick
Clinical Pharmacology and Therapeutics Branch, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Department of Health and Human Services, Baltimore, MD 21224, USA
Am Heart J 151:754.e1-754.e5. 2006..In human studies, activation of CB1 receptors by cannabis or its active ingredient, Delta9-tetrahydrocannabinol (THC), has modest and inconsistent effects on BP... - Human cocaine-seeking behavior and its control by drug-associated stimuli in the laboratoryLeigh V Panlilio
Preclinical Pharmacology Section, Intramural Research Program, National Institute on Drug Abuse, Baltimore, MD, USA
Neuropsychopharmacology 30:433-43. 2005..The similarity of the response patterns in humans and animals also supports the use of second-order schedules in animals as a valid model of human drug seeking... - Effect of tobacco deprivation on the attentional blink in rapid serial visual presentationAdrienne Heinz
Clinical Pharmacology and Therapeutics Branch, National Institute on Drug Abuse, NIH, Baltimore, Maryland 21224, USA
Hum Psychopharmacol 22:89-96. 2007..These results suggest that the AB is influenced by stimulus duration, but not by 12 h of tobacco deprivation... - Heroin and cocaine craving and use during treatment: measurement validation and potential relationshipsAdrienne J Heinz
Clinical Pharmacology and Therapeutics Branch, Intramural Research Program, National Institute on Drug Abuse, Baltimore, MD 21224, USA
J Subst Abuse Treat 31:355-64. 2006..Treatment dropout and in-treatment drug use were more frequently predicted by scores on the 14- or 45-item CCQ than by VAS ratings. Results suggest that the CCQ/HCQ and the 14-item CCQ provide information that unidimensional VASs do not... - Novel use of a lipid-lowering fibrate medication to prevent nicotine reward and relapse: preclinical findingsLeigh V Panlilio
Intramural Research Program, Preclinical Pharmacology Section, Department of Health and Human Services, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD, USA
Neuropsychopharmacology 37:1838-47. 2012..The fact that fibrates are already approved for human use could expedite clinical trials and subsequent implementation of fibrates as a treatment for tobacco dependence, especially in smokers with abnormal lipid profiles... - Tobacco craving predicts lapse to smoking among adolescent smokers in cessation treatmentKara S Bagot
National Institute on Drug Abuse, Intramural Research Program, Baltimore, MD 21224, USA
Nicotine Tob Res 9:647-52. 2007..Thus monitoring and addressing craving appears useful to increase the success of adolescent smoking cessation... - Age at menarche and weight concerns in relation to smoking trajectory and dependence among adolescent girls enrolled in a smoking cessation trialMaria Jaszyna-Gasior
National Institute on Drug Abuse, Intramural Research Program, National Institutes of Health, Department of Health and Human Services, Biomedical Research Center, Baltimore, Maryland 21224, USA
Addict Behav 34:92-5. 2009..Findings support previous research showing that early maturation represents a risk factor for substance use. Further study in larger samples that include non-treatment-seeking adolescent female smokers is warranted... - Divided versus selective attention: evidence for common processing mechanismsBritta Hahn
NIH National Institute on Drug Abuse IRP, Neuroimaging Research Branch, 5500 Nathan Shock Drive, Baltimore, MD 21224, USA
Brain Res 1215:137-46. 2008..Increased activity appears to reflect additional processing demands by introducing a secondary task, but those demands do not appear to qualitatively differ from processes of selective attention... - Tobacco, cocaine, and heroin: Craving and use during daily lifeDavid H Epstein
Clinical Pharmacology and Therapeutics Research Branch, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD 21224, USA
Addict Behav 35:318-24. 2010..Relationships among tobacco smoking, tobacco craving, and other drug use and craving may have treatment implications in polydrug-dependent individuals... - Safety and efficacy of the nicotine patch and gum for the treatment of adolescent tobacco addictionEric T Moolchan
Teen Tobacco Addiction Research Clinic, Clinical Pharmacology and Therapeutics Research Branch, National Institute on Drug Abuse, Intramural Research Program, 5500 Nathan Shock Dr, Baltimore, Maryland 21224, USA
Pediatrics 115:e407-14. 2005..To determine the safety and efficacy of the nicotine patch and gum for adolescents who want to quit smoking... - Group independent component analysis reveals consistent resting-state networks across multiple sessionsSharon Chen
Neuroimaging Research Branch, National Institute on Drug Abuse, NIH, 251 Bayview Boulevard, Suite 200, Baltimore, MD 21224, USA
Brain Res 1239:141-51. 2008..The consistency of these maps suggests that, at least over a period of several weeks, these networks would be useful to follow longitudinal treatment-related manipulations... - Reliability and validity of the Tobacco Craving Questionnaire and validation of a craving-induction procedure using multiple measures of craving and moodEdward G Singleton
National Institute on Drug Abuse, Intramural Research Program, Baltimore, MD 21224, USA
Addiction 98:1537-46. 2003.... - Clonidine blocks stress-induced craving in cocaine usersMichelle L Jobes
Clinical Pharmacology and Therapeutics Research Branch, Intramural Research Program, National Institute on Drug Abuse, 251 Bayview Blvd, Suite 200, Baltimore, MD 21224, USA
Psychopharmacology (Berl) 218:83-8. 2011..In rodents, alpha-2 adrenergic agonists such as clonidine block stress-induced reinstatement of drug seeking, but not drug cue-induced reinstatement... - Self-administration of cannabinoids by experimental animals and human marijuana smokersZuzana Justinova
Preclinical Pharmacology Section, Behavioral Neuroscience Research Branch, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Department of Health and Human Services, Baltimore, MD 21224, USA
Pharmacol Biochem Behav 81:285-99. 2005.... - Methods for clinical research involving cannabis administrationDavid A Gorelick
Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD, USA
Methods Mol Med 123:235-53. 2006..Subjects should not be discharged from research participation until reevaluation has shown that they have returned to baseline status... - Nicotine enhances alerting, but not executive, attention in smokers and nonsmokersCarol S Myers
Intramural Research Program, National Institute on Drug Abuse, Baltimore, MD 21224, USA
Nicotine Tob Res 15:277-81. 2013..The purpose of this study was to determine the effects of nicotine on executive and alerting attention in smokers and nonsmokers... - Breath carbon monoxide and semiquantitative saliva cotinine as biomarkers for smokingGina F Marrone
Nicotine Psychopharmacology Section, Intramural Research Program, National Institute on Drug Abuse, Baltimore, MD, USA
Hum Psychopharmacol 25:80-3. 2010..Recent studies have used urine NicAlert and breath CO in combination to verify abstinence. However, no studies have evaluated the performance of saliva NicAlert against or in combination with breath CO... - Strategies for quitting among non-treatment-seeking marijuana smokersSusan J Boyd
Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse, Intramural Research Program, Baltimore, MD 21224, USA
Am J Addict 14:35-42. 2005..Clinicians are likely to see marijuana users in their practice and should be proactive in offering assistance, incorporating the strategies reported here into treatment plans for their marijuana-using patients... - Nicotine serves as an effective reinforcer of intravenous drug-taking behavior in human cigarette smokersDeon M Harvey
Clinical Pharmacology and Therapeutics Branch, National Institute on Drug Abuse, NIH, DHHS, Baltimore, MD 21224, USA
Psychopharmacology (Berl) 175:134-42. 2004..Subjects adjusted their responding to response requirements in a way that maintained relatively constant levels of nicotine injections per session... - Assessment of cannabis craving using the Marijuana Craving QuestionnaireStephen J Heishman
Clinical Pharmacology and Therapeutics Branch, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD, USA
Methods Mol Med 123:209-16. 2006..In a treatment setting, the MCQ should be administered at intake and during and at the end of treatment... - Effects of the cannabinoid-1 receptor antagonist rimonabant on psychiatric symptoms in overweight people with schizophrenia: a randomized, double-blind, pilot studyDeanna L Kelly
Maryland Psychiatric Research Center, University of Maryland School of Medicine, Baltimore, MD 21228, USA
J Clin Psychopharmacol 31:86-91. 2011..The endocannabinoid system remains a promising target for pharmacotherapy of schizophrenia and obesity... - Reliability and validity of the French version of the tobacco craving questionnaireIvan Berlin
Service de Pharmacologie, Centre Hospitalier Universitaire Pitie Salpetriere, 47, Bd de l Hopital, FR 75013 Paris, France
Eur Addict Res 11:62-8. 2005..2) To compare the two different language versions of the same instrument in 2 independent samples from 2 cultures in 2 distinct time periods... - Associations between Cloninger's temperament dimensions and acute tobacco withdrawalAdam M Leventhal
Center for Alcohol and Addiction Studies, Brown University, Box G S121, Providence, RI 02912, USA
Addict Behav 32:2976-89. 2007..Smokers with different temperaments display different patterns of acute tobacco withdrawal, and may benefit from treatments matched to their particular abstinence profile... - Enhanced identification of smoking-related words during the attentional blink in smokersAndrew J Waters
Department of Behavioral Science, UT M D Anderson Cancer Center, Houston, TX 77030, USA
Addict Behav 32:3077-82. 2007..These data indicate that, in heavy smokers, smoking-related stimuli are more likely to engage conscious awareness than neutral words under conditions of limited attentional resources... - Tobacco, nicotine, and human cognitionStephen J Heishman
Nicotine Tob Res 4:3-4. 2002