Research Topics
| Rohan HazraSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
Tenofovir disoproxil fumarate and an optimized background regimen of antiretroviral agents as salvage therapy for pediatric HIV infectionRohan Hazra
HIV and AIDS Malignancy Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
Pediatrics 116:e846-54. 2005..Loss of BMD may limit tenofovir DF use among prepubertal patients...
Growing up with HIV: children, adolescents, and young adults with perinatally acquired HIV infectionRohan Hazra
Pediatric, Adolescent and Maternal AIDS Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Center for Research for Mothers and Children, National Institutes of Health, Rockville, Maryland 20852, USA
Annu Rev Med 61:169-85. 2010....- Immunologic, virologic, and neuropsychologic responses in human immunodeficiency virus-infected children receiving their first highly active antiretroviral therapy regimenRohan Hazra
HIV and AIDS Malignancy Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892 1868, USA
Viral Immunol 20:131-41. 2007.... - Lipid levels in the second year of life among HIV-infected and HIV-exposed uninfected Latin American childrenRohan Hazra
Pediatric, Adolescent, and Maternal AIDS Branch, CRMC NICHD NIH, Bethesda, MD 20892 7510, USA
AIDS 26:235-40. 2012..Dyslipidemia is observed among older children and adults with HIV. We examined nonfasting cholesterol and triglycerides in two groups of 12-23-month-old Latin American children - HIV-infected vs. HIV-exposed but uninfected (HEU)... - Tenofovir disoproxil fumarate and an optimized background regimen of antiretroviral agents as salvage therapy: impact on bone mineral density in HIV-infected childrenRachel I Gafni
HIV and AIDS Malignancy Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
Pediatrics 118:e711-8. 2006..Decreases in bone mineral density correlate with decreases in viral load and young age, suggesting that young responders may be at greater risk for bone toxicity... 
Decreased bone mineral density with off-label use of tenofovir in children and adolescents infected with human immunodeficiency virusJulia B Purdy
HIV and AIDS Malignancy Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
J Pediatr 152:582-4. 2008..1 subject was the smallest child and experienced a 27% decrease, necessitating withdrawal of TDF. Subsequently, her BMD recovered. Monitoring of children infected with HIV who require treatment with TDF is warranted...- Dyslipidemia in a cohort of HIV-infected Latin American children receiving highly active antiretroviral therapyMargaret Brewinski
Pediatric, Adolescent and Maternal AIDS Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development NICHD, National Institutes of Health, Bethesda, MD 20892 7510, USA
J Trop Pediatr 57:324-32. 2011..In conclusion, HIV-infected youth receiving PI-containing HAART in this Latin American cohort were at increased risk for hypercholesterolemia and hypertriglyceridemia compared with those receiving NNRTI-containing HAART... - Natural history of lipid abnormalities and fat redistribution among human immunodeficiency virus-infected children receiving long-term, protease inhibitor-containing, highly active antiretroviral therapy regimensPerdita Taylor
Pediatric HIV Working Group, HIV and AIDS Malignancy Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
Pediatrics 114:e235-42. 2004.... - Emergence of human immunodeficiency virus type 1 variants containing the Q151M complex in children receiving long-term antiretroviral chemotherapyShigeyoshi Harada
Experimental Retrovirology Section, HIV and AIDS Malignancy Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
Antiviral Res 75:159-66. 2007..These data suggest that the Q151M could be prevalent in pediatric patients with long-term NRTI monotherapy and/or dual NRTI regimens and that HAART regimens containing TDF may be meritorious in such patients... - Virologic response using directly observed therapy in adolescents with HIV: an adherence toolJulia Bilodeau Purdy
National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
J Assoc Nurses AIDS Care 19:158-65. 2008..A period of clinic-monitored DOT may allow diagnosis of nonadherence, discussion of medication barriers, and avoidance of unnecessary medication changes... - Safety of tenofovir use during pregnancy: early growth outcomes in HIV-exposed uninfected infantsGeorge K Siberry
Pediatric Adolescent Maternal AIDS Branch, Eunice Kennedy Shriver National Institutes of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA
AIDS 26:1151-9. 2012..To evaluate the association of tenofovir disoproxil fumarate (TDF) use during pregnancy with early growth parameters in HIV-exposed, uninfected (HEU) infants... - Evaluation of viral load thresholds for predicting new World Health Organization stage 3 and 4 events in HIV-infected children receiving highly active antiretroviral therapyGeorge K Siberry
Pediatric, Adolescent, and Maternal AIDS Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892 7510, USA
J Acquir Immune Defic Syndr 60:214-8. 2012..This study evaluated a wide range of viral load (VL) thresholds to identify a cut-point that best predicts new clinical events in children on stable highly active antiretroviral therapy (HAART)... - CD4+ lymphocyte-based immunologic outcomes of perinatally HIV-infected children during antiretroviral therapy interruptionGeorge K Siberry
Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA
J Acquir Immune Defic Syndr 57:223-9. 2011..To assess the characteristics and outcomes of antiretroviral treatment (ART) interruption (TI) in perinatally HIV-infected children... - Cognitive functioning in school-aged children with vertically acquired HIV infection being treated with highly active antiretroviral therapy (HAART)Staci C Martin
HIV and AIDS Malignancy Branch, National Cancer Institute, 9030 Old Georgetown Road, Bethesda, MD 20814, USA
Dev Neuropsychol 30:633-57. 2006..Findings emphasize the importance of conducting neuropsychological assessments in this population, particularly for children with cortical atrophy and absolute CD4+ cell counts < or = 500... - Longitudinal assessment of metabolic abnormalities in adolescents and young adults with HIV-infection acquired perinatally or in early childhoodDavid Dimock
Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA
Metabolism 60:874-80. 2011..002). Impaired glucose tolerance, insulin resistance, dyslipidemia, and microalbuminuria are common among young adults with HIV. Long-term exposure to therapy may translate into substantial persistent metabolic risk... - Family functioning and coping styles in families of children with cancer and HIV diseaseStaci Martin
National Cancer Institute, Bethesda, MD, USA
Clin Pediatr (Phila) 51:58-64. 2012..Researchers should avoid combining various illness groups indiscriminately. Likewise, clinicians should be sensitive to disease-specific factors when helping families learn to cope with illness-related stressors... - High rate of coronary artery abnormalities in adolescents and young adults infected with human immunodeficiency virus early in lifeIrene J Mikhail
National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, MD 20892 1662, USA
Pediatr Infect Dis J 30:710-2. 2011..More than 50% of participants (14/27) had evidence of CAA. Individuals had a high rate of CAA, suggesting possible early atherosclerosis... - Planning Future Strategies for Domestic and International NeuroAIDS Research, July 24-25, 2008Jeymohan Joseph
HIV Pathogenesis, Neuropsychiatry and Treatment Branch, Center for Mental Health Research on AIDS, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
J Neuroimmune Pharmacol 4:283-97. 2009..Several critical research areas in neuroAIDS were identified as areas of emphasis. Opportunities for collaborations between large NIH-funded projects were also discussed... - Guidelines for the Prevention and Treatment of Opportunistic Infections among HIV-exposed and HIV-infected children: recommendations from CDC, the National Institutes of Health, the HIV Medicine Association of the Infectious Diseases Society of America, tLynne M Mofenson
National Institutes of Health, Bethesda, Maryland, USA
MMWR Recomm Rep 58:1-166. 2009..nih.gov... - Thymic function in HIV infectionRohan Hazra
Pediatric Oncology Branch, National Cancer Institute, Bldg. 10-CRC Rm. 1W-3940, 10 Center Drive, MSC 1104, Bethesda, MD 20892, USA
Curr HIV/AIDS Rep 2:24-8. 2005..Recent work has demonstrated that some HIV strains, especially those that are CXCR4 trophic, are more thymotoxic and may contribute to irreversible thymic damage in this population... - Evidence of human immunodeficiency virus type 1 infection of nestin-positive neural progenitors in archival pediatric brain tissueLynnae Schwartz
Laboratory of Molecular Medicine and Neuroscience, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892 1296, USA
J Neurovirol 13:274-83. 2007..HIV-1 or viral DNA was identified in nestin-positive cells in four of seven HIV-1-infected children, suggesting in vivo infection of neural progenitors... - Single-dose and steady-state pharmacokinetics of tenofovir disoproxil fumarate in human immunodeficiency virus-infected childrenRohan Hazra
HIV and AIDS Malignancy Branch, Biostatistics and Data Management Section, National Cancer Institute, Bethesda, Maryland, USA
Antimicrob Agents Chemother 48:124-9. 2004..h/ml; C(max), approximately 300 ng/ml) treated with tenofovir DF at 300 mg... - HIV-1 viral escape in infancy followed by emergence of a variant-specific CTL responseMargaret E Feeney
Partners AIDS Research Center and Infectious Disease Division, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
J Immunol 174:7524-30. 2005..Taken together, these findings indicate that the developing immune system of children may exhibit greater plasticity in responding to a continually evolving chronic viral infection...