S R Haynes

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi Primary structure of Drosophila ribosomal protein L14 and identification of conserved protein motifs
    S R Haynes
    Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA
    DNA Seq 8:105-8. 1997
  2. ncbi Involvement of a tissue-specific RNA recognition motif protein in Drosophila spermatogenesis
    S R Haynes
    Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892 2785, USA
    Mol Cell Biol 17:2708-15. 1997
  3. ncbi The Drosophila Hrb loci: a family of hnRNA binding proteins
    S R Haynes
    Laboratory of Molecular Genetics, NICHD, NIH, Bethesda, MD 20892
    Mol Biol Rep 14:93-4. 1990
  4. ncbi Rasputin, the Drosophila homologue of the RasGAP SH3 binding protein, functions in ras- and Rho-mediated signaling
    C Pazman
    LMG, NICHD, NIH, MSC 2785, Bethesda, MD 20892, USA
    Development 127:1715-25. 2000
  5. ncbi The Drosophila Hrb98DE locus encodes four protein isoforms homologous to the A1 protein of mammalian heterogeneous nuclear ribonucleoprotein complexes
    S R Haynes
    Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, Bethesda, Maryland 20892
    Mol Cell Biol 10:316-23. 1990
  6. ncbi The Rb97D gene encodes a potential RNA-binding protein required for spermatogenesis in Drosophila
    I Karsch-Mizrachi
    Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892
    Nucleic Acids Res 21:2229-35. 1993
  7. ncbi Association of RB97D, an RRM protein required for male fertility, with a Y chromosome lampbrush loop in Drosophila spermatocytes
    V M Heatwole
    Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892 2785, USA
    Chromosoma 105:285-92. 1996
  8. ncbi The Drosophila fsh locus, a maternal effect homeotic gene, encodes apparent membrane proteins
    S R Haynes
    Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, Bethesda, Maryland 20892
    Dev Biol 134:246-57. 1989
  9. ncbi Cabeza, a Drosophila gene encoding a novel RNA binding protein, shares homology with EWS and TLS, two genes involved in human sarcoma formation
    D T Stolow
    Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA
    Nucleic Acids Res 23:835-43. 1995
  10. ncbi The Drosophila Hrb87F gene encodes a new member of the A and B hnRNP protein group
    S R Haynes
    Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892
    Nucleic Acids Res 19:25-31. 1991

Collaborators

  • Igor B Dawid
  • B A Mozer
  • M Mlodzik
  • C Pazman
  • V M Heatwole
  • K Zu
  • M Fanto
  • C A Mayes
  • D T Stolow
  • A L Beyer
  • I Karsch-Mizrachi
  • M L Sikes
  • G Raychaudhuri
  • A J MacKrell
  • M E Digan
  • M Gans
  • J H Fessler
  • B Blumberg
  • F Forquignon

Detail Information

Publications16

  1. ncbi Primary structure of Drosophila ribosomal protein L14 and identification of conserved protein motifs
    S R Haynes
    Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA
    DNA Seq 8:105-8. 1997
    ..The sizes of the L14 proteins vary between different species, with most of the variability confined to the C-terminal region...
  2. ncbi Involvement of a tissue-specific RNA recognition motif protein in Drosophila spermatogenesis
    S R Haynes
    Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892 2785, USA
    Mol Cell Biol 17:2708-15. 1997
    ....
  3. ncbi The Drosophila Hrb loci: a family of hnRNA binding proteins
    S R Haynes
    Laboratory of Molecular Genetics, NICHD, NIH, Bethesda, MD 20892
    Mol Biol Rep 14:93-4. 1990
  4. ncbi Rasputin, the Drosophila homologue of the RasGAP SH3 binding protein, functions in ras- and Rho-mediated signaling
    C Pazman
    LMG, NICHD, NIH, MSC 2785, Bethesda, MD 20892, USA
    Development 127:1715-25. 2000
    ..These data suggest that Rin is not a general component of polarity generation, but serves a function specific to Ras and RhoA signaling pathways...
  5. ncbi The Drosophila Hrb98DE locus encodes four protein isoforms homologous to the A1 protein of mammalian heterogeneous nuclear ribonucleoprotein complexes
    S R Haynes
    Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, Bethesda, Maryland 20892
    Mol Cell Biol 10:316-23. 1990
    ..We suggest that these sequence differences could affect the affinities of the proteins for RNA or other protein components of heterogeneous nuclear RNP complexes, leading to differences in function...
  6. ncbi The Rb97D gene encodes a potential RNA-binding protein required for spermatogenesis in Drosophila
    I Karsch-Mizrachi
    Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892
    Nucleic Acids Res 21:2229-35. 1993
    ..Analysis of a mutant containing a P element inserted into the 5' untranslated region of the gene demonstrates that Rb97D is required for male fertility. Possible models for the function of Rb97D in testes are discussed...
  7. ncbi Association of RB97D, an RRM protein required for male fertility, with a Y chromosome lampbrush loop in Drosophila spermatocytes
    V M Heatwole
    Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892 2785, USA
    Chromosoma 105:285-92. 1996
    ..These results demonstrate that the proteins that bind lampbrush loops can be essential for fertility. Since RB97D was present only premeiotically, its function is likely to be directly related to the metabolism of the C loop transcripts...
  8. ncbi The Drosophila fsh locus, a maternal effect homeotic gene, encodes apparent membrane proteins
    S R Haynes
    Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, Bethesda, Maryland 20892
    Dev Biol 134:246-57. 1989
    ..We suggest that the expression of fsh proteins in the membrane of the embryo is required for proper functioning of genes such as Ubx in the specification of segmental identity...
  9. ncbi Cabeza, a Drosophila gene encoding a novel RNA binding protein, shares homology with EWS and TLS, two genes involved in human sarcoma formation
    D T Stolow
    Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA
    Nucleic Acids Res 23:835-43. 1995
    ..Therefore, it appears that these genes constitute a new sub-family of RNA binding proteins...
  10. ncbi The Drosophila Hrb87F gene encodes a new member of the A and B hnRNP protein group
    S R Haynes
    Laboratory of Molecular Genetics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892
    Nucleic Acids Res 19:25-31. 1991
    ..Sequence identities among the Drosophila Hrb proteins and the vertebrate A and B hnRNP proteins suggest that these proteins may form a distinct subfamily within the larger family of related RNA binding proteins...
  11. ncbi The bromodomain: a conserved sequence found in human, Drosophila and yeast proteins
    S R Haynes
    Laboratory of Molecular Genetics, NICHD, NIH, Bethesda, MD 20892
    Nucleic Acids Res 20:2603. 1992
  12. ncbi Altered levels of the Drosophila HRB87F/hrp36 hnRNP protein have limited effects on alternative splicing in vivo
    K Zu
    Department of Microbiology, University of Virginia, Charlottesville 22908, USA
    Mol Biol Cell 7:1059-73. 1996
    ....
  13. ncbi Heterogeneous nuclear ribonucleoprotein complexes and proteins in Drosophila melanogaster
    G Raychaudhuri
    Department of Microbiology, University of Virginia School of Medicine, Charlottesville 22908
    Mol Cell Biol 12:847-55. 1992
    ..melanogaster and mammals...
  14. ncbi pen repeat sequences are GGN clusters and encode a glycine-rich domain in a Drosophila cDNA homologous to the rat helix destabilizing protein
    S R Haynes
    Proc Natl Acad Sci U S A 84:1819-23. 1987
    ..We suggest that we have cloned a cDNA encoding a Drosophila single-stranded nucleic acid binding protein...
  15. ncbi Genetic and molecular analysis of fs(1)h, a maternal effect homeotic gene in Drosophila
    M E Digan
    Dev Biol 114:161-9. 1986
    ..9 kb, which are homologous to the fs(1)h+ chromosomal region, are found in ovaries and early embryos. The largest RNAs are derived from a 20-kb chromosomal region encompassing the sites of all mapped fs(1)h alleles...
  16. ncbi The lethal myospheroid gene of Drosophila encodes a membrane protein homologous to vertebrate integrin beta subunits
    A J MacKrell
    Molecular Biology Institute, University of California, Los Angeles 90024
    Proc Natl Acad Sci U S A 85:2633-7. 1988
    ....