R B Hayes

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Hemochromatosis gene mutations and distal adenomatous colorectal polyps
    Katherine A McGlynn
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, EPS 7060, 6120 Executive Boulevard, Rockville, MD 20852 7234, USA
    Cancer Epidemiol Biomarkers Prev 14:158-63. 2005
  2. pmc SLC6A3 and body mass index in the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial
    Elizabeth M Azzato
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, Maryland, USA
    BMC Med Genet 10:9. 2009
  3. ncbi request reprint Benzene and lymphohematopoietic malignancies in humans
    R B Hayes
    Division of Cancer Epidemiology and Genetics, U S National Cancer Institute, Bethesda, Maryland 20892, USA
    Am J Ind Med 40:117-26. 2001
  4. ncbi request reprint Benzene and lymphohematopoietic malignancies in China
    R B Hayes
    Division of Cancer Epidemiology and Genetics, U S National Cancer Institute, Bethesda, Maryland 20892, USA
    J Toxicol Environ Health A 61:419-32. 2000
  5. ncbi request reprint Methods for etiologic and early marker investigations in the PLCO trial
    Richard B Hayes
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, EPS 8114, Bethesda, MD 20892, USA
    Mutat Res 592:147-54. 2005
  6. ncbi request reprint Whole blood cryopreservation in epidemiological studies
    Richard B Hayes
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892, USA
    Cancer Epidemiol Biomarkers Prev 11:1496-8. 2002
  7. ncbi request reprint Dietary factors and risks for prostate cancer among blacks and whites in the United States
    R B Hayes
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892, USA
    Cancer Epidemiol Biomarkers Prev 8:25-34. 1999
  8. ncbi request reprint Dietary and nutritional factors and pancreatic cancer: a case-control study based on direct interviews
    D T Silverman
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    J Natl Cancer Inst 90:1710-9. 1998
  9. pmc Mortality among benzene-exposed workers in China
    R B Hayes
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892 7368, USA
    Environ Health Perspect 104:1349-52. 1996
  10. ncbi request reprint Genotoxic markers among butadiene polymer workers in China
    R B Hayes
    Occupational Studies Branch, National Cancer Institute, Bethesda, MD, USA
    Carcinogenesis 21:55-62. 2000

Detail Information

Publications94

  1. ncbi request reprint Hemochromatosis gene mutations and distal adenomatous colorectal polyps
    Katherine A McGlynn
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, EPS 7060, 6120 Executive Boulevard, Rockville, MD 20852 7234, USA
    Cancer Epidemiol Biomarkers Prev 14:158-63. 2005
    ..These results do not support a relationship between HFE heterozygosity and risk of advanced distal adenoma...
  2. pmc SLC6A3 and body mass index in the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial
    Elizabeth M Azzato
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, Maryland, USA
    BMC Med Genet 10:9. 2009
    ....
  3. ncbi request reprint Benzene and lymphohematopoietic malignancies in humans
    R B Hayes
    Division of Cancer Epidemiology and Genetics, U S National Cancer Institute, Bethesda, Maryland 20892, USA
    Am J Ind Med 40:117-26. 2001
    ..S. rubber workers. An epidemiologic investigation in China (NCI/CAPM study) extended quantitative evaluations of cancer risk to a broader range of benzene exposures, particularly at lower levels...
  4. ncbi request reprint Benzene and lymphohematopoietic malignancies in China
    R B Hayes
    Division of Cancer Epidemiology and Genetics, U S National Cancer Institute, Bethesda, Maryland 20892, USA
    J Toxicol Environ Health A 61:419-32. 2000
    ..A new study would include expanded data collection for cases of hematopoietic malignancy and related disorders and for an appropriate control series...
  5. ncbi request reprint Methods for etiologic and early marker investigations in the PLCO trial
    Richard B Hayes
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, EPS 8114, Bethesda, MD 20892, USA
    Mutat Res 592:147-54. 2005
    ..g., diet), biochemical, and genetic factors. Early detection studies focus on blood-based biologic markers of early disease. Clinical epidemiology is also an important component of the PLCO trial...
  6. ncbi request reprint Whole blood cryopreservation in epidemiological studies
    Richard B Hayes
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892, USA
    Cancer Epidemiol Biomarkers Prev 11:1496-8. 2002
    ..Whole blood cryopreservation is a cost-effective approach to large-scale storage of viable cells in epidemiological studies...
  7. ncbi request reprint Dietary factors and risks for prostate cancer among blacks and whites in the United States
    R B Hayes
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892, USA
    Cancer Epidemiol Biomarkers Prev 8:25-34. 1999
    ..A reduction of fat from animal sources in the diet could lead to decreased incidence and mortality rates for prostate cancer, particularly among American blacks...
  8. ncbi request reprint Dietary and nutritional factors and pancreatic cancer: a case-control study based on direct interviews
    D T Silverman
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    J Natl Cancer Inst 90:1710-9. 1998
    ..We evaluated whether dietary factors could explain the higher incidence of pancreatic cancer experienced by black Americans compared with white Americans...
  9. pmc Mortality among benzene-exposed workers in China
    R B Hayes
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892 7368, USA
    Environ Health Perspect 104:1349-52. 1996
    ..01) and lung cancer (ptrend = 0.01) increased with increasing cumulative exposure to benzene. Investigations continue to relate benzene exposure to specific lymphatic and hematopoietic malignancies and other causes of death...
  10. ncbi request reprint Genotoxic markers among butadiene polymer workers in China
    R B Hayes
    Occupational Studies Branch, National Cancer Institute, Bethesda, MD, USA
    Carcinogenesis 21:55-62. 2000
    ..Overall, the study demonstrated exposure to butadiene in these workers, by a variety of short-term and long-term measures, but did not show specific genotoxic effects, at the chromosomal or gene levels, related to that exposure...
  11. ncbi request reprint Alcohol dehydrogenase 3 genotype and risk of oral cavity and pharyngeal cancers
    L C Harty
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7372, USA
    J Natl Cancer Inst 89:1698-705. 1997
    ....
  12. pmc Indirect validation of benzene exposure assessment by association with benzene poisoning
    M Dosemeci
    Division of Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA
    Environ Health Perspect 104:1343-7. 1996
    ..Our confidence in the assessment method is supported by the observation of a strong positive trend between benzene poisoning and various measures, especially recent intensity of exposure to benzene...
  13. pmc An epidemiologic study of early biologic effects of benzene in Chinese workers
    N Rothman
    Division of Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA
    Environ Health Perspect 104:1365-70. 1996
    ....
  14. pmc Clinical features of hematopoietic malignancies and related disorders among benzene-exposed workers in China. Benzene Study Group
    M S Linet
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892 7368, USA
    Environ Health Perspect 104:1353-64. 1996
    ....
  15. ncbi request reprint Validation of benzene exposure assessment
    M Dosemeci
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892, USA
    Ann N Y Acad Sci 837:114-21. 1997
    ..This sharp trend between benzene hematotoxicity and estimated exposure to benzene indicated that the exposure-estimation method used in this cancer epidemiology study is reliable...
  16. pmc Urinary excretion of phenol, catechol, hydroquinone, and muconic acid by workers occupationally exposed to benzene
    N Rothman
    Occupational Studies Branch, National Cancer Institute, Bethesda, MD, USA
    Occup Environ Med 55:705-11. 1998
    ..To determine if this occurs in humans, benzene metabolites in urine samples collected as part of a cross sectional study of occupationally exposed workers in Shanghai, China were measured...
  17. ncbi request reprint Mouthwash in the etiology of oral cancer in Puerto Rico
    D M Winn
    Division of Cancer Control and Population Sciences, Bethesda, MD 20892 7395, USA
    Cancer Causes Control 12:419-29. 2001
    ..To determine if the risk of cancers of the mouth and pharynx is associated with mouthwash use in Puerto Rico, an area of relatively high risk...
  18. ncbi request reprint Occupational exposure to pesticides and pancreatic cancer
    B T Ji
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Am J Ind Med 39:92-9. 2001
    ..An increased risk of exposure to pesticides for pancreatic cancer has been suggested in a number of epidemiologic studies...
  19. ncbi request reprint Diet and nutrition as risk factors for multiple myeloma among blacks and whites in the United States
    L M Brown
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892-7244, USA
    Cancer Causes Control 12:117-25. 2001
    ..In addition, the increasing prevalence of obesity may have contributed to the upward trend in the incidence of multiple myeloma during recent decades...
  20. ncbi request reprint Benzene poisoning, a risk factor for hematological malignancy, is associated with the NQO1 609C-->T mutation and rapid fractional excretion of chlorzoxazone
    N Rothman
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA
    Cancer Res 57:2839-42. 1997
    ..Further evaluation of susceptibility for hematotoxicity and hematological malignancy among workers with a history of occupational exposure to benzene is warranted...
  21. ncbi request reprint Markers for carcinogenicity among butadiene-polymer workers in China
    R B Hayes
    Occupational Epidemology Branch, National Cancer Institute, National Institutes of Health, EPS 8114, Bethesda, MD, USA
    Chem Biol Interact 135:455-64. 2001
    ..Overall, the study demonstrated exposure to butadiene in these workers, by a variety of short-term and long-term measures, but did not show specific genotoxic effects, at the chromosomal or gene levels, related to that exposure...
  22. pmc Meat consumption and the risk of incident distal colon and rectal adenoma
    L M Ferrucci
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
    Br J Cancer 106:608-16. 2012
    ..Most studies of meat and colorectal adenoma have investigated prevalent events from a single screening, thus limiting our understanding of the role of meat and meat-related exposures in early colorectal carcinogenesis...
  23. ncbi request reprint Cancer surveillance series: interpreting trends in prostate cancer--part I: Evidence of the effects of screening in recent prostate cancer incidence, mortality, and survival rates
    B F Hankey
    Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD 20892, USA
    J Natl Cancer Inst 91:1017-24. 1999
    ..Detailed data are presented for whites because the size of the population allows for calculating statistically reliable rates; however, similar overall trends are seen for African-Americans and other races...
  24. ncbi request reprint Evidence of a healthy volunteer effect in the prostate, lung, colorectal, and ovarian cancer screening trial
    P F Pinsky
    Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    Am J Epidemiol 165:874-81. 2007
    ..Standardized incidence ratios for all cancer were 84 in women and 73 in men, with a large range of standardized incidence ratios observed for specific cancers...
  25. pmc Height and risk of prostate cancer in the prostate, lung, colorectal, and ovarian cancer screening trial
    J Ahn
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD 20852, USA
    Br J Cancer 101:522-5. 2009
    ..The relationship between prostate cancer and height is uncertain...
  26. ncbi request reprint Serum lycopene, other serum carotenoids, and risk of prostate cancer in US Blacks and Whites
    T M Vogt
    Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT, USA
    Am J Epidemiol 155:1023-32. 2002
    ..In conclusion, the results, though not statistically significant, suggest that serum lycopene is inversely related to prostate cancer risk in US Blacks and Whites...
  27. ncbi request reprint Time dependency in human cancer
    R B Hayes
    Division of Cancer Etiology, National Cancer Institute, Bethesda, Maryland 20892
    Tumori 75:189-95. 1989
    ..Rather than trying to define exposure-disease relationships as being characterized by a long or a short latency period, it seems more promising to study the temporal sequence of disease development as a multistep process...
  28. pmc Using biomarkers of genetic susceptibility to enhance the study of cancer etiology
    N Rothman
    Environmental Epidemiology Branch, National Cancer Institute, Bethesda, Maryland, USA
    Environ Health Perspect 103:291-5. 1995
    ..Biologic assays are now available to evaluate many of these functions at the DNA and phenotype level and can be readily incorporated into studies of cancer etiology...
  29. ncbi request reprint Is shorter always better? Relative importance of questionnaire length and cognitive ease on response rates and data quality for two dietary questionnaires
    A F Subar
    Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD 20892 7344, USA
    Am J Epidemiol 153:404-9. 2001
    ..These data indicated that the shorter FFQ was not better from the perspective of response rate and data quality, and that clarity and ease of administration may compensate for questionnaire length...
  30. ncbi request reprint Mortality among workers exposed to cutting oil mist: update of previous reports
    N Kazerouni
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20892, USA
    Am J Ind Med 38:410-6. 2000
    ..The present report describes the mortality experience of these workers followed for mortality through 1980...
  31. ncbi request reprint Family cancer history and susceptibility to oral carcinoma in Puerto Rico
    L M Brown
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892 7244, USA
    Cancer 92:2102-8. 2001
    ..A heritable component to oral carcinoma risk also has been suggested, although only limited data are available on familial aggregation of this disease...
  32. pmc Aspirin but not ibuprofen use is associated with reduced risk of prostate cancer: a PLCO study
    F M Shebl
    Department of Human Health and Services, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Rockville, MD, USA
    Br J Cancer 107:207-14. 2012
    ..Although most epidemiological studies suggest that non-steroidal anti-inflammatory drug use is inversely associated with prostate cancer risk, the magnitude and specificity of this association remain unclear...
  33. pmc Sexual behaviour, STDs and risks for prostate cancer
    R B Hayes
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
    Br J Cancer 82:718-25. 2000
    ..Syphilis, gonorrhoea, sex with prostitutes and unprotected sexual intercourse may be indicators of contact with a sexually transmissible factor that increases the risk of prostate cancer...
  34. pmc Tobacco use and sinonasal cancer: a case-control study
    R B Hayes
    Environmental Epidemiology Branch, National Cancer Institute, Bethesda, MD 20892
    Br J Cancer 56:843-6. 1987
    ..The study findings indicate that tobacco use, and in particular recent tobacco use, is associated with the development of squamous cell sinonasal cancer...
  35. ncbi request reprint Collection of genomic DNA from adults in epidemiological studies by buccal cytobrush and mouthwash
    M Garcia-Closas
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20852 7234, USA
    Cancer Epidemiol Biomarkers Prev 10:687-96. 2001
    ....
  36. ncbi request reprint A common 8q24 variant in prostate and breast cancer from a large nested case-control study
    Fredrick R Schumacher
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
    Cancer Res 67:2951-6. 2007
    ..590). Although the gene responsible has yet to be identified, the validation of this marker in this large sample of prostate cancer cases leaves little room for the possibility of a false-positive result...
  37. ncbi request reprint Insulin resistance-related genes and advanced left-sided colorectal adenoma
    Marc J Gunter
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland, USA
    Cancer Epidemiol Biomarkers Prev 16:703-8. 2007
    ....
  38. ncbi request reprint Serum lycopene, other carotenoids, and prostate cancer risk: a nested case-control study in the prostate, lung, colorectal, and ovarian cancer screening trial
    Ulrike Peters
    Cancer Prevention Program, Fred Hutchinson Cancer Research Center, P O Box 19024, 1100 Fairview Avenue North M4 B402, Seattle, WA 98109 1024, USA
    Cancer Epidemiol Biomarkers Prev 16:962-8. 2007
    ..This has stimulated extensive laboratory and clinical research, as well as much commercial and public enthusiasm. However, the epidemiologic evidence remains inconclusive...
  39. ncbi request reprint Genome-wide association study of prostate cancer identifies a second risk locus at 8q24
    Meredith Yeager
    SAIC Frederick, National Cancer Institute NCI Frederick Cancer Research and Development Center, Frederick, Maryland 21702, USA
    Nat Genet 39:645-9. 2007
    ..We estimate that the population attributable risk of the new locus, marked by rs6983267, is higher than the locus marked by rs1447295 (21% versus 9%)...
  40. ncbi request reprint Genetic variation at the CYP19A1 locus predicts circulating estrogen levels but not breast cancer risk in postmenopausal women
    Christopher A Haiman
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, Los Angeles, CA 90033, USA
    Cancer Res 67:1893-7. 2007
    ..Thus, although genetic variation in CYP19A1 produces measurable differences in estrogen levels among postmenopausal women, the magnitude of the change was insufficient to contribute detectably to breast cancer...
  41. ncbi request reprint Genetic variation in base excision repair genes and the prevalence of advanced colorectal adenoma
    Sonja I Berndt
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Cancer Res 67:1395-404. 2007
    ..51; 95% CI, 0.33-0.78, P = 0.002 for PARP1 A284A). This study suggests that polymorphisms in APEX1, XRCC1, and PARP1 may be associated with advanced colorectal adenoma...
  42. ncbi request reprint Carbohydrate, glycemic index, and glycemic load and colorectal adenomas in the Prostate, Lung, Colorectal, and Ovarian Screening Study
    Andrew Flood
    University of Minnesota, Minneapolis, MN, Henry Ford Hospital, Detroit, MI, USA
    Am J Clin Nutr 84:1184-92. 2006
    ..It is possible that high-glycemic-load diets, through their hyperinsulinemic effects, can increase the risk of colorectal cancer...
  43. ncbi request reprint Cigarette smoking, N-acetyltransferase genes and the risk of advanced colorectal adenoma
    Roxana Moslehi
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, 6120 Executive Blvd, EPS 8047, Rockville, MD 20852 USA
    Pharmacogenomics 7:819-29. 2006
    ..Our interest is in the polymorphisms within the NAT1 and NAT2 genes that influence the tobacco-colorectal tumor relationship by impacting on the metabolic activation and detoxification of tobacco smoke-derived carcinogens...
  44. ncbi request reprint Occupational exposures and head and neck cancers among Swedish construction workers
    Mark P Purdue
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, EPS 8111, Rockville, MD 20852, USA
    Scand J Work Environ Health 32:270-5. 2006
    ..In an attempt to address this issue, the relationship between selected occupational exposures and head and neck cancer risk was investigated using data from a large cohort of Swedish construction workers...
  45. ncbi request reprint Polymorphisms in genes involved in DNA double-strand break repair pathway and susceptibility to benzene-induced hematotoxicity
    Min Shen
    Division of Cancer Epidemiology and Genetics, NCI, NIH, DHHS, Bethesda, MD 20892, USA
    Carcinogenesis 27:2083-9. 2006
    ..The effect of BRCA2 Ex11 +1487 A > G polymorphism was limited to granulocytes. These results suggest that genetic polymorphisms in WRN, TP53 and BRCA2 that maintain genomic stability impact benzene-induced hematotoxicity...
  46. ncbi request reprint IGF-1 and IGFBP-3: Risk of prostate cancer among men in the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial
    Jocelyn M Weiss
    Division of Cancer Epidemiology and Genetics, NCI NIH, Bethesda, MD, USA
    Int J Cancer 121:2267-73. 2007
    ..11-7.08). In summary, our large prospective study showed no overall association between the insulin-like growth factor axis and prostate cancer risk, however, IGFmr was related to risk for aggressive prostate cancer in obese men...
  47. ncbi request reprint Functional variant of manganese superoxide dismutase (SOD2 V16A) polymorphism is associated with prostate cancer risk in the prostate, lung, colorectal, and ovarian cancer study
    Daehee Kang
    Department of Preventive Medicine, Seoul National University College of Medicine, 28 Yongon Dong, Chongno Gu, Seoul 110 799, Korea
    Cancer Epidemiol Biomarkers Prev 16:1581-6. 2007
    ..These results suggest that the Ala variant of SOD2 is associated with moderately increased risk of prostate cancer, particularly among men with lower intakes of dietary and supplemental vitamin E...
  48. ncbi request reprint Prospective study of fruit and vegetable intake and risk of prostate cancer
    Victoria A Kirsh
    Research Unit, Division of Preventive Oncology, Cancer Care Ontario, Toronto, ON, Canada
    J Natl Cancer Inst 99:1200-9. 2007
    ..Several epidemiologic studies have reported associations between fruit and vegetable intake and reduced risk of prostate cancer, but the findings are inconsistent and data on clinically relevant advanced prostate cancer are limited...
  49. ncbi request reprint RNASEL Arg462Gln polymorphism and prostate cancer in PLCO
    Sarah E Daugherty
    Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
    Prostate 67:849-54. 2007
    ..The relationship of this variant to sporadic prostate cancer remains uncertain...
  50. doi request reprint Meta-analysis and pooled analysis of GSTM1 and CYP1A1 polymorphisms and oral and pharyngeal cancers: a HuGE-GSEC review
    Leonor Varela-Lema
    Department of Preventive Medicine and Public Health, University of Santiago de Compostela, Santiago de Compostela, Spain
    Genet Med 10:369-84. 2008
    ..1-4.5) in ever smokers. A joint effect was observed for GSTM1 homozygous deletion and the CYP1A1 m1m2 variant on cancer risk. Our findings suggest that tobacco use and genetic factors play a significant role in oral and pharyngeal cancer...
  51. doi request reprint Variation in the selenoenzyme genes and risk of advanced distal colorectal adenoma
    Ulrike Peters
    Public Health Science, Fred Hutchinson Cancer Research Center, PO Box 19024, Seattle, WA 98109 1024, USA
    Cancer Epidemiol Biomarkers Prev 17:1144-54. 2008
    ..We therefore investigated whether genetic variants in selenoenzymes abundantly expressed in the colon are associated with advanced colorectal adenoma, a cancer precursor...
  52. pmc Common variants near MC4R are associated with fat mass, weight and risk of obesity
    Ruth J F Loos
    MRC Epidemiology Unit, Addenbrooke s Hospital, Cambridge CB2 0QQ, UK
    Nat Genet 40:768-75. 2008
    ....
  53. doi request reprint Multiple loci identified in a genome-wide association study of prostate cancer
    Gilles Thomas
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
    Nat Genet 40:310-5. 2008
    ..Our findings point to multiple loci with moderate effects associated with susceptibility to prostate cancer that, taken together, in the future may predict high risk in select individuals...
  54. doi request reprint TNF polymorphisms and prostate cancer risk
    Kim N Danforth
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, Maryland 20852, USA
    Prostate 68:400-7. 2008
    ..Inflammation has been hypothesized to increase prostate cancer risk. Tumor necrosis factor (TNF) is an important mediator of the inflammatory process, but the relationship between TNF variants and prostate cancer remains unclear...
  55. doi request reprint Endogenous sex hormones and the risk of prostate cancer: a prospective study
    Jocelyn M Weiss
    Division of Cancer Epidemiology and Genetics, NCI, NIH, Bethesda, MD, USA
    Int J Cancer 122:2345-50. 2008
    ..T:SHBG ratio was related to risk in this older population of men, but the significance of this ratio in steroidal biology is unclear. (c) 2008 Wiley-Liss, Inc...
  56. ncbi request reprint Dairy products, calcium intake, and risk of prostate cancer in the prostate, lung, colorectal, and ovarian cancer screening trial
    Jiyoung Ahn
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, 6120 Executive Boulevard, Bethesda, MD 20892, USA
    Cancer Epidemiol Biomarkers Prev 16:2623-30. 2007
    ..Furthermore, we found no relationship between calcium intake and circulating vitamin D...
  57. ncbi request reprint Fruit and vegetable intake and prevalence of colorectal adenoma in a cancer screening trial
    Amy E Millen
    University at Buffalo, School of Public Health and Health Professions, Department of Social and Preventive Medicine, Buffalo, NY 14214 8001, USA
    Am J Clin Nutr 86:1754-64. 2007
    ..Research on the association between fruit and vegetable intake and risk of colorectal adenoma is inconclusive...
  58. ncbi request reprint CYP17 genetic variation and risk of breast and prostate cancer from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3)
    Veronica Wendy Setiawan
    Department of Preventive Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Cancer Epidemiol Biomarkers Prev 16:2237-46. 2007
    ..Our findings do not support the hypothesis that common germ line variation in CYP17 makes a substantial contribution to postmenopausal breast or prostate cancer susceptibility...
  59. ncbi request reprint Polymorphic variants in PTGS2 and prostate cancer risk: results from two large nested case-control studies
    Kim N Danforth
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20852, USA
    Carcinogenesis 29:568-72. 2008
    ....
  60. ncbi request reprint Sequence variants of estrogen receptor beta and risk of prostate cancer in the National Cancer Institute Breast and Prostate Cancer Cohort Consortium
    Yen Ching Chen
    Channing Laboratory, 181 Longwood Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 16:1973-81. 2007
    ..Estrogen receptor beta (ESR2) may play a role in modulating prostate carcinogenesis through the regulation of genes related to cell proliferation and apoptosis...
  61. ncbi request reprint Variants in the alpha-Methylacyl-CoA racemase gene and the association with advanced distal colorectal adenoma
    Sarah E Daugherty
    Divison of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, 6120 Executive Boulevard, EPS Rm 8113, Bethesda, MD 20892, USA
    Cancer Epidemiol Biomarkers Prev 16:1536-42. 2007
    ..AMACR gene variants have been associated with hereditary prostate cancer, but no studies have evaluated their etiologic role in colorectal carcinogenesis...
  62. ncbi request reprint Tobacco smoking and colorectal hyperplastic and adenomatous polyps
    Bu Tian Ji
    National Cancer Institute, 6120 Executive Boulevard, EPS 8120, Bethesda, MD 20852, USA
    Cancer Epidemiol Biomarkers Prev 15:897-901. 2006
    ..In conclusion, tobacco use, particularly recent use, increases risk for both adenomatous and hyperplastic polyps, but the risks are substantially greater for hyperplastic lesions...
  63. ncbi request reprint Genetic polymorphisms of interleukin-1B (IL-1B), IL-6, IL-8, and IL-10 and risk of prostate cancer
    Dominique S Michaud
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892, USA
    Cancer Res 66:4525-30. 2006
    ..At least seven common polymorphisms in genes of inflammatory cytokines IL-1B, IL-6, IL-8, and IL-10 do not seem to play a role in the risk of prostate cancer...
  64. ncbi request reprint High serum selenium and reduced risk of advanced colorectal adenoma in a colorectal cancer early detection program
    Ulrike Peters
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, Maryland, USA
    Cancer Epidemiol Biomarkers Prev 15:315-20. 2006
    ..Although substantial evidence suggests that smoking is a strong effect modifier for other antioxidative nutrients, little is known about smoking-selenium interactions in colorectal tumors...
  65. ncbi request reprint The prostate, lung, colon, and ovarian (PLCO) cancer screening trial: Status and promise
    Gerald L Andriole
    Division of Urologic Surgery, Washington University School of Medicine, Washington University in St Louis, 4960 Children s Place, Campus Box 8242, St Louis, MO 63110, USA
    Urol Oncol 22:358-61. 2004
    ..Together, the data derived from the intervention and control arms and material in the biorepository provide a valuable resource to allow identification and testing of novel biomarkers for human disease...
  66. ncbi request reprint Occupation, pesticide exposure and risk of multiple myeloma
    Dalsu Baris
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institute of Health, Department of Health and Human Services, Bethesda, Maryland 20892, United States
    Scand J Work Environ Health 30:215-22. 2004
    ..This population-based case-control study examined the relationship between occupation, living or working on a farm, pesticide exposure, and the risk of multiple myeloma...
  67. ncbi request reprint Metabolic polymorphisms, smoking, and oral cancer in Puerto Rico
    Heng Xie
    Division of Cancer Treatment and Diagnosis, National Cancer Institute, Bethesda, MD 20892, USA
    Oncol Res 14:315-20. 2004
    ..4). In conclusion, cigarette use significantly increased the risk of oral cancer in this population. The GSTM1-present genotype was associated with higher tobacco-associated risk for oral cancer among heavy smokers than the null genotype...
  68. ncbi request reprint Mortality from solid cancers among workers in formaldehyde industries
    Michael Hauptmann
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Bethesda, MD 20892, USA
    Am J Epidemiol 159:1117-30. 2004
    ..In this cohort of formaldehyde-industry workers, some evidence was found of an exposure-response relation with mortality from nasopharyngeal cancer (based on small numbers) but not for cancers of the pancreas, brain, lung, or prostate...
  69. pmc Lack of increased genetic damage in 1,3-butadiene-exposed Chinese workers studied in relation to EPHX1 and GST genotypes
    Luoping Zhang
    School of Public Health, University of California, 140 Warren Hall, Berkeley, CA 94720 7360, USA
    Mutat Res 558:63-74. 2004
    ..Together, these studies suggest that low levels of occupational BD exposure do not pose a significant risk of genetic damage...
  70. ncbi request reprint Detailed exposure assessment for a molecular epidemiology study of benzene in two shoe factories in China
    Roel Vermeulen
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, 6120 Executive Boulevard, Rockville, MD 20892, USA
    Ann Occup Hyg 48:105-16. 2004
    ..Our goal was to identify workers with a broad range of benzene exposures, for an epidemiologic study relating exposure to early biologic effects...
  71. ncbi request reprint Mortality from lymphohematopoietic malignancies among workers in formaldehyde industries
    Michael Hauptmann
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    J Natl Cancer Inst 95:1615-23. 2003
    ..We extended follow-up of a cohort of industrial workers to evaluate the association between formaldehyde exposure and lymphohematopoietic cancers...
  72. ncbi request reprint Multiple biomarkers study in painters in a shipyard in Korea
    Kyoung Ho Lee
    Department of Preventive Medicine, Institute of Environmental Medicine, Seoul National University College of Medicine, SNUMRC, 28 Yongon Dong, Chongno Gu, Seoul 110 799, South Korea
    Mutat Res 540:89-98. 2003
    ..These results suggest that painters in the shipyard were exposed to significant amounts of PAHs and possibly to other genotoxic aromatic compounds, and that urinary 1-OHPG may be a potential biomarker of PAH exposure in this population...
  73. ncbi request reprint Alcohol concentration and risk of oral cancer in Puerto Rico
    Wen Yi Huang
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
    Am J Epidemiol 157:881-7. 2003
    ..These results suggest that alcohol concentration is a risk factor for oral cancer independent of the total quantity of alcohol consumed...
  74. ncbi request reprint Dietary fibre and colorectal adenoma in a colorectal cancer early detection programme
    Ulrike Peters
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, US National Institutes of Health, DHHS, MD 20892 7273, USA
    Lancet 361:1491-5. 2003
    ..Although dietary fibre has been reported to have no association with colorectal adenoma and cancer, in some studies this topic remains controversial...
  75. ncbi request reprint Epidemiologic considerations to assess altered DNA methylation from environmental exposures in cancer
    Lee E Moore
    Occupational Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892, USA
    Ann N Y Acad Sci 983:181-96. 2003
    ..Methods for incorporating markers of DNA methylation status into etiologic investigations of the impact of environmental exposures on disease (e.g., cancer) are discussed...
  76. ncbi request reprint Height and the survival of prostate cancer patients
    Honglei Chen
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Cancer Epidemiol Biomarkers Prev 12:215-8. 2003
    ..Our results suggest that greater height may be associated with better survival of prostate cancer patients...
  77. ncbi request reprint Serum selenium and risk of prostate cancer in U.S. blacks and whites
    Tara M Vogt
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7246, USA
    Int J Cancer 103:664-70. 2003
    ..S. blacks. Since selenium exposure varies widely throughout the world, further research on optimal concentrations for cancer prevention is justified...
  78. ncbi request reprint Sinonasal cancer and occupational exposures: a pooled analysis of 12 case-control studies
    Daniele Luce
    INSERM Unité 88, Hopital, National de Saint Maurice, Saint Maurice, France
    Cancer Causes Control 13:147-57. 2002
    ..In order to examine the associations between sinonasal cancer and occupational exposures other than wood dust and leather dust, the data from 12 case-control studies conducted in seven countries were pooled and reanalyzed...
  79. ncbi request reprint Impact of misclassification in genotype-exposure interaction studies: example of N-acetyltransferase 2 (NAT2), smoking, and bladder cancer
    Anne C Deitz
    Center for Cancer Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, USA
    Cancer Epidemiol Biomarkers Prev 13:1543-6. 2004
    ..This example illustrates how reducing genotype misclassification can result in substantial decreases in sample size requirements and possibly substantial decreases in the cost of studies to evaluate interactions...
  80. pmc Hematotoxicity in workers exposed to low levels of benzene
    Qing Lan
    Division of Cancer Epidemiology and Genetics, National Cancer Institute NCI, National Institutes of Health NIH, Department of Health and Human Services DHHS, Bethesda, MD 20892, USA
    Science 306:1774-6. 2004
    ..Thus, hematotoxicity from exposure to benzene occurred at air levels of 1 ppm or less and may be particularly evident among genetically susceptible subpopulations...
  81. ncbi request reprint Supplemental and dietary vitamin E, beta-carotene, and vitamin C intakes and prostate cancer risk
    Victoria A Kirsh
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD 20892, USA
    J Natl Cancer Inst 98:245-54. 2006
    ....
  82. ncbi request reprint A prospective study of lycopene and tomato product intake and risk of prostate cancer
    Victoria A Kirsh
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Bethesda, MD 20892, USA
    Cancer Epidemiol Biomarkers Prev 15:92-8. 2006
    ..Dietary lycopene and tomato products may reduce risk of prostate cancer; however, uncertainty remains about this possible association...
  83. ncbi request reprint DNA repair gene polymorphisms and risk of second primary neoplasms and mortality in oral cancer patients
    Thomas J Gal
    Department of Otolaryngology Head and Neck Surgery, School of Medicine, University of Washington, Seattle, Washington 98195, USA
    Laryngoscope 115:2221-31. 2005
    ....
  84. pmc Genetic variation in the HSD17B1 gene and risk of prostate cancer
    Peter Kraft
    Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America
    PLoS Genet 1:e68. 2005
    ..These results suggest that the germline variants in HSD17B1 characterized by these htSNPs do not substantially influence the risk of prostate cancer in U.S. and European whites...
  85. ncbi request reprint Polymorphisms in cytokine and cellular adhesion molecule genes and susceptibility to hematotoxicity among workers exposed to benzene
    Qing Lan
    Division of Cancer Epidemiology, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, MD 20892 7240, USA
    Cancer Res 65:9574-81. 2005
    ..041) and increased (P = 0.076) CFU-GEMM progenitor cell colony formation in 29 benzene-exposed workers. This is the first report to provide evidence that SNPs in genes that regulate hematopoiesis influence benzene-induced hematotoxicity...
  86. ncbi request reprint Meat, meat cooking methods and preservation, and risk for colorectal adenoma
    Rashmi Sinha
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland, USA
    Cancer Res 65:8034-41. 2005
    ..04; 95% CI, 0.90-1.19). Our study of screening-detected colorectal adenomas shows that red meat and meat cooked at high temperatures are associated with an increased risk of colorectal adenoma...
  87. ncbi request reprint Hormone replacement therapy, reproductive history, and colorectal adenomas: data from the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial (United States)
    Mark P Purdue
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, MSC 7240, Executive Plaza South 8121, Rockville, MD 20892, USA
    Cancer Causes Control 16:965-73. 2005
    ....
  88. ncbi request reprint Insulin-like growth factor-I and insulin are associated with the presence and advancement of adenomatous polyps
    Robert E Schoen
    Department of Medicine, University of Pittsburgh, Pennsylvania 15213, USA
    Gastroenterology 129:464-75. 2005
    ..We evaluated the relationship of insulin, IGF-I, insulin-like growth factor binding protein (IGFBP) 3, and visceral adipose tissue (VAT) in subjects with adenomatous polyps, the precursor lesion of colorectal cancer...
  89. ncbi request reprint GSTM1, GSTT1, and GSTP1 polymorphisms and risk of advanced colorectal adenoma
    Lee E Moore
    National Cancer Institute, 6120 Executive Boulevard, EPS 7034, Bethesda, MD 20892 7240, USA
    Cancer Epidemiol Biomarkers Prev 14:1823-7. 2005
    ..These findings only became apparent using a newly developed assay able to distinguish heterozygous from wild-type individuals. Our data provide evidence that phenotypic differences between these two groups exist...
  90. ncbi request reprint Selected genetic polymorphisms in MGMT, XRCC1, XPD, and XRCC3 and risk of head and neck cancer: a pooled analysis
    Wen Yi Huang
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, EPS 8113, MSC 7240, Bethesda, MD 20892, USA
    Cancer Epidemiol Biomarkers Prev 14:1747-53. 2005
    ..Consistent findings from three case-control studies suggest that selected DNA repair enzymes may play a role in head and neck carcinogenesis...
  91. ncbi request reprint NAT2 slow acetylation and bladder cancer in workers exposed to benzidine
    Tania Carreon
    Division of Surveillance, Hazard Evaluations and Field Studies, National Institute for Occupational Safety and Health, Cincinnati, OH 45226, USA
    Int J Cancer 118:161-8. 2006
    ..Study findings suggest the existence of key differences in the metabolism of mono- and diarylamines...
  92. ncbi request reprint Microsatellite polymorphisms in the epidermal growth factor receptor (EGFR) gene and the transforming growth factor-alpha (TGFA) gene and risk of oral cancer in Puerto Rico
    Daehee Kang
    Department of Preventive Medicine, Seoul National University College of Medicine, Cancer Research Institute, SNUCM, Seoul, Korea
    Pharmacogenet Genomics 15:343-7. 2005
    ....
  93. ncbi request reprint Association of genetic variants in the calcium-sensing receptor with risk of colorectal adenoma
    Ulrike Peters
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Rockville, MD, USA
    Cancer Epidemiol Biomarkers Prev 13:2181-6. 2004
    ..We assessed the associations between CASR gene variants and risk for colorectal adenoma, a cancer precursor. We further investigated gene-diet interactions between the CASR variants and calcium intake on adenoma risk...
  94. ncbi request reprint Folate intake, serum homocysteine and methylenetetrahydrofolate reductase (MTHFR) C677T genotype are not associated with oral cancer risk in Puerto Rico
    Stephanie J Weinstein
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
    J Nutr 132:762-7. 2002
    ..Risks for oral cancer are not folate specific; preventive recommendations for this disease should emphasize the importance of a healthy diet, including substantial intake of fruits...