- lacZ reporter system for use in Borrelia burgdorferiBeth M Hayes
Laboratory of Zoonotic Pathogens, Rocky Mountain Laboratories, Hamilton, MT 59840, USA
Appl Environ Microbiol 76:7407-12. 2010..The addition of lacZ to the repertoire of genetic tools available for use in B. burgdorferi should contribute to a better understanding of how B. burgdorferi gene expression is regulated during the infectious cycle...
- Global repression of host-associated genes of the Lyme disease spirochete through post-transcriptional modulation of the alternative sigma factor RpoSDaniel P Dulebohn
Laboratory of Zoonotic Pathogens, Rocky Mountain Laboratories, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America
PLoS ONE 9:e93141. 2014..We propose that BBD18 is a novel regulator of RpoS and its activity likely represents a first step in the transition from an RpoS-ON to an RpoS-OFF state, when spirochetes transition from the host to the tick vector. ..
- Regulation of the virulence determinant OspC by bbd18 on linear plasmid lp17 of Borrelia burgdorferiAmit Sarkar
Laboratory of Zoonotic Pathogens, Rocky Mountain Laboratories, NIAID NIH, 903 S 4th Street, Hamilton, MT 59840, USA
J Bacteriol 193:5365-73. 2011..These data identify a novel component of ospC regulation and provide the basis for determining the molecular mechanisms of ospC repression in vivo...