M Hauptmann

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint The use of sliding time windows for the exploratory analysis of temporal effects of smoking histories on lung cancer risk
    M Hauptmann
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Stat Med 19:2185-94. 2000
  2. ncbi request reprint Analysis of exposure-time-response relationships using a spline weight function
    M Hauptmann
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Ingolstadter Landstrasse 1, 85764 Neuherberg, Germany
    Biometrics 56:1105-8. 2000
  3. ncbi request reprint The exposure-time-response relationship between occupational asbestos exposure and lung cancer in two German case-control studies
    Michael Hauptmann
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7244, USA
    Am J Ind Med 41:89-97. 2002
  4. ncbi request reprint Mortality from lymphohematopoietic malignancies among workers in formaldehyde industries
    Michael Hauptmann
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    J Natl Cancer Inst 95:1615-23. 2003
  5. ncbi request reprint Mortality from solid cancers among workers in formaldehyde industries
    Michael Hauptmann
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Bethesda, MD 20892, USA
    Am J Epidemiol 159:1117-30. 2004
  6. ncbi request reprint Retrospective biodosimetry among United States radiologic technologists
    Parveen Bhatti
    Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD, USA
    Radiat Res 167:727-34. 2007
  7. ncbi request reprint Cancer and other causes of mortality among radiologic technologists in the United States
    Aparna K Mohan
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7244, USA
    Int J Cancer 103:259-67. 2003
  8. pmc Interventional radiography and mortality risks in U.S. radiologic technologists
    Martha S Linet
    Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892-7238, USA
    Pediatr Radiol 36:113-20. 2006
  9. pmc Risk of cataract after exposure to low doses of ionizing radiation: a 20-year prospective cohort study among US radiologic technologists
    Gabriel Chodick
    Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 7238, USA
    Am J Epidemiol 168:620-31. 2008
  10. ncbi request reprint Using splines to analyse latency in the Colorado Plateau uranium miners cohort
    M Hauptmann
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda MD 20892-7244, USA
    J Epidemiol Biostat 6:417-24. 2001

Detail Information

Publications37

  1. ncbi request reprint The use of sliding time windows for the exploratory analysis of temporal effects of smoking histories on lung cancer risk
    M Hauptmann
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Neuherberg, Germany
    Stat Med 19:2185-94. 2000
    ..Among different smoking profiles that result in the same lifelong cumulative number of cigarettes smoked, those with a concentration of smoked cigarettes within 20 years before interview bear substantially larger risk than others...
  2. ncbi request reprint Analysis of exposure-time-response relationships using a spline weight function
    M Hauptmann
    GSF National Research Center for Environment and Health, Institute of Epidemiology, Ingolstadter Landstrasse 1, 85764 Neuherberg, Germany
    Biometrics 56:1105-8. 2000
    ..The method is evaluated in a simulation study and is applied to data on smoking histories and lung cancer from a recent case-control study in Germany...
  3. ncbi request reprint The exposure-time-response relationship between occupational asbestos exposure and lung cancer in two German case-control studies
    Michael Hauptmann
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7244, USA
    Am J Ind Med 41:89-97. 2002
    ..Numerous studies have been carried out to evaluate the association between lung cancer and occupational asbestos exposure. However, the effects of timing of exposure have not been analyzed thoroughly...
  4. ncbi request reprint Mortality from lymphohematopoietic malignancies among workers in formaldehyde industries
    Michael Hauptmann
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    J Natl Cancer Inst 95:1615-23. 2003
    ..We extended follow-up of a cohort of industrial workers to evaluate the association between formaldehyde exposure and lymphohematopoietic cancers...
  5. ncbi request reprint Mortality from solid cancers among workers in formaldehyde industries
    Michael Hauptmann
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Bethesda, MD 20892, USA
    Am J Epidemiol 159:1117-30. 2004
    ..In this cohort of formaldehyde-industry workers, some evidence was found of an exposure-response relation with mortality from nasopharyngeal cancer (based on small numbers) but not for cancers of the pancreas, brain, lung, or prostate...
  6. ncbi request reprint Retrospective biodosimetry among United States radiologic technologists
    Parveen Bhatti
    Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD, USA
    Radiat Res 167:727-34. 2007
    ..S. radiologic technologists...
  7. ncbi request reprint Cancer and other causes of mortality among radiologic technologists in the United States
    Aparna K Mohan
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7244, USA
    Int J Cancer 103:259-67. 2003
    ....
  8. pmc Interventional radiography and mortality risks in U.S. radiologic technologists
    Martha S Linet
    Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892-7238, USA
    Pediatr Radiol 36:113-20. 2006
    ..The present study cannot rule out increased risks of cerebrovascular disease, specific cancers, and diseases with low case-fatality rates or a long latency period preceding death...
  9. pmc Risk of cataract after exposure to low doses of ionizing radiation: a 20-year prospective cohort study among US radiologic technologists
    Gabriel Chodick
    Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 7238, USA
    Am J Epidemiol 168:620-31. 2008
    ....
  10. ncbi request reprint Using splines to analyse latency in the Colorado Plateau uranium miners cohort
    M Hauptmann
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda MD 20892-7244, USA
    J Epidemiol Biostat 6:417-24. 2001
    ..CONCLUSIONS: The proposed spline model is a flexible tool for latency analyses, and extends previously used methods...
  11. ncbi request reprint Occupation and adult-onset asthma among Chinese women in a population-based cohort
    Srmena Krstev
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, Maryland 20892, USA
    Am J Ind Med 50:265-73. 2007
    ..We examined the associations between occupation and asthma among women in a case-control study nested in the population-based Shanghai Women's Health Study cohort in China...
  12. ncbi request reprint Lung cancer risk among US radiologic technologists, 1983-1998
    Preetha Rajaraman
    Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, NCI, NIH, DHHS, Bethesda, MD 20892 7238, USA
    Int J Cancer 119:2481-6. 2006
    ..Overall, we find very limited evidence that chronic low-to-moderate dose occupational exposure increased lung cancer risk in the US Radiologic Technologist cohort...
  13. ncbi request reprint Smoking cigarettes before first childbirth and risk of breast cancer
    Mina Ha
    Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
    Am J Epidemiol 166:55-61. 2007
    ....
  14. ncbi request reprint Cigarette smoking and cancer risk: modeling total exposure and intensity
    Jay H Lubin
    Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
    Am J Epidemiol 166:479-89. 2007
    ..The intensity effects were statistically homogeneous, indicating that after accounting for risk from total pack-years, intensity patterns were comparable across the diverse cancer sites...
  15. ncbi request reprint Polymorphisms in DNA repair genes, ionizing radiation exposure and risk of breast cancer in U.S. Radiologic technologists
    Parveen Bhatti
    Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD 20892 7238, USA
    Int J Cancer 122:177-82. 2008
    ..The suggestive evidence found for modification of radiation-related breast cancer risk for 5 of the 55 SNPs evaluated requires confirmation in larger studies of women with quantified radiation breast doses in the low-to-moderate range...
  16. ncbi request reprint Polymorphisms in apoptosis- and proliferation-related genes, ionizing radiation exposure, and risk of breast cancer among U.S. Radiologic Technologists
    Alice J Sigurdson
    Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, 6120 Executive Boulevard, EPS 7092, MSC 7238, Bethesda, MD 20892 7238, USA
    Cancer Epidemiol Biomarkers Prev 16:2000-7. 2007
    ..For this reason, potential modification of the relationship between ionizing radiation exposure and breast cancer risk by polymorphic apoptosis gene variants have not been investigated among radiation-exposed women...
  17. pmc Occupation and breast cancer risk among Shanghai women in a population-based cohort study
    Bu Tian Ji
    National Cancer Institute, NIH, DHHS, Bethesda, Maryland 20852, USA
    Am J Ind Med 51:100-10. 2008
    ..A total of 74,942 female subjects were recruited in a population-based cohort study in Shanghai, China between 1997 and 2000. We examined the relationship between occupation and breast cancer risk...
  18. pmc Mortality from lymphohematopoietic malignancies among workers in formaldehyde industries: the National Cancer Institute Cohort
    Laura E Beane Freeman
    Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD 20892, USA
    J Natl Cancer Inst 101:751-61. 2009
    ....
  19. ncbi request reprint Estimating historical radiation doses to a cohort of U.S. radiologic technologists
    Steven L Simon
    Division of Cancer Epidemiology and Genetics, National Cancer Institute NCI, National Institutes of Health, Bethesda, Maryland, USA
    Radiat Res 166:174-92. 2006
    ..The models and predictions presented here, while continuing to be modified and improved, represent one of the most comprehensive dose reconstructions undertaken to date for a large cohort of medical radiation workers...
  20. ncbi request reprint Cancer incidence in the US radiologic technologists health study, 1983-1998
    Alice J Sigurdson
    Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
    Cancer 97:3080-9. 2003
    ..However, characterizing risk at low doses requires large populations and ideally should include a large proportion of women, both of which rarely are available...
  21. ncbi request reprint Risk of melanoma among radiologic technologists in the United States
    D Michal Freedman
    Division of Cancer Epidemiology and Genetics, Radiation Epidemiology Branch, National Cancer Institute, Executive Plaza South, Room 7087, 6120 Executive Boulevard, Bethesda, MD 20892, USA
    Int J Cancer 103:556-62. 2003
    ....
  22. ncbi request reprint Site-specific cancer incidence and mortality after cerebral angiography with radioactive thorotrast
    Lois B Travis
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, Maryland 20892, USA
    Radiat Res 160:691-706. 2003
    ..Nonetheless, the substantial risks associated with liver cancer and leukemia indicate that unique and prolonged exposure to alpha-particle-emitting Thorotrast increased carcinogenic risks...
  23. pmc Kin-cohort estimates for familial breast cancer risk in relation to variants in DNA base excision repair, BRCA1 interacting and growth factor genes
    Alice J Sigurdson
    Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, 6120 Executive Boulevard, Bethesda, Maryland, 20892 7238, USA
    BMC Cancer 4:9. 2004
    ..Thus, 19 single nucleotide polymorphisms (SNPs) in eight genes involved in base excision repair (XRCC1, APEX, POLD1), BRCA1 protein interaction (BRIP1, ZNF350, BRCA2), and growth regulation (TGFss1, IGFBP3) were evaluated...
  24. ncbi request reprint Nonmelanoma skin cancer in relation to ionizing radiation exposure among U.S. radiologic technologists
    Shinji Yoshinaga
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
    Int J Cancer 115:828-34. 2005
    ..013 and 0.027, respectively). This study provides some evidence that chronic occupational exposure to IR at low to moderate levels can increase the risk of BCC, and that this risk may be modified by pigmentation characteristics...
  25. ncbi request reprint DNA damage among thyroid cancer and multiple cancer cases, controls, and long-lived individuals
    Alice J Sigurdson
    Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, 6120 Executive Boulevard, EPS 7092, MSC 7238, Bethesda, MD 20892 7238, USA
    Mutat Res 586:173-88. 2005
    ..Measuring this DNA damage phenotype may contribute to the identification of susceptible sub-groups. Our observations require replication in a prospective study with a large number of pre-diagnostic samples...
  26. ncbi request reprint Breast cancer incidence in U.S. radiologic technologists
    Michele Morin Doody
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892 7238, USA
    Cancer 106:2707-15. 2006
    ....
  27. ncbi request reprint Mortality from diseases of the circulatory system in radiologic technologists in the United States
    Michael Hauptmann
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
    Am J Epidemiol 157:239-48. 2003
    ..007 and < 0.001, respectively). The data suggest increased mortality from diseases of the circulatory system with occupational radiation exposure before 1950 when radiation doses were likely high...
  28. pmc Incidence of haematopoietic malignancies in US radiologic technologists
    M S Linet
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Bethesda, MD 20892, USA
    Occup Environ Med 62:861-7. 2005
    ..There are limited data on risks of haematopoietic malignancies associated with protracted low-to-moderate dose radiation...
  29. ncbi request reprint Breast cancer mortality among female radiologic technologists in the United States
    Aparna K Mohan
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7244, USA
    J Natl Cancer Inst 94:943-8. 2002
    ..The high risks of breast cancer mortality for women exposed to occupational radiation prior to 1950 and the subsequent decline in risk are consistent with the dramatic reduction in recommended radiation exposure limits over time...
  30. pmc Low level alcohol intake, cigarette smoking and risk of breast cancer in Asian-American women
    Linda Morris Brown
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
    Breast Cancer Res Treat 120:203-10. 2010
    ....
  31. pmc International study of factors affecting human chromosome translocations
    Alice J Sigurdson
    Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD, USA
    Mutat Res 652:112-21. 2008
    ..Our data provide stable estimates of background TF by age, gender, race, and smoking status and suggest an acceleration of chromosome damage above age 60 and among those with a history of smoking cigarettes...
  32. ncbi request reprint A case-control study of dietary phytoestrogens and testicular cancer risk
    Farzana L Walcott
    Department of Epidemiology, University of Texas, M D Anderson Cancer Center, Houston, TX 77030, USA
    Nutr Cancer 44:44-51. 2002
    ..This hypothesis-generating study does not support the premise that dietary phytoestrogens increase or decrease testicular cancer risk in young men...
  33. ncbi request reprint Re: Population-based, case-control study of HER2 genetic polymorphism and breast cancer risk
    Michael Hauptmann
    J Natl Cancer Inst 95:1251-2. 2003
  34. ncbi request reprint Treatment-related risk factors for premature menopause following Hodgkin lymphoma
    Marie L De Bruin
    Department of Epidemiology, The Netherlands Cancer Institute, Amsterdam
    Blood 111:101-8. 2008
    ..As long as alkylating agents will be used for curing HL, premature menopause will remain a frequent adverse treatment effect, with various clinical implications...
  35. ncbi request reprint A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer
    Katrien Berns
    Division of Molecular Carcinogenesis and Center for Biomedical Genetics, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands
    Cancer Cell 12:395-402. 2007
    ..Thus, assessment of PI3K pathway activation may provide a biomarker to identify patients unlikely to respond to trastuzumab-based therapy...
  36. ncbi request reprint Relationship between clinical factors and the incidence of toxicity after intra-arterial chemoradiation for head and neck cancer
    Guido B van den Broek
    Department of Head and Neck Oncology and Surgery, Academic Medical Centre, Amsterdam, The Netherlands
    Radiother Oncol 81:143-50. 2006
    ..This study was set up to determine the relationship between patient-, tumour- and treatment-related factors and acute/late toxicity after concomitant chemoradiation...
  37. ncbi request reprint Thyroid cancer and employment as a radiologic technologist
    Erik W Zabel
    Division of Environmental Health Sciences, School of Public Health, University of Minnesota, Minneapolis, MN 55455, USA
    Int J Cancer 119:1940-5. 2006
    ..04, 95% CI = 1.01-10.78). These data provide modest evidence of an association between employment as a radiologic technologist and thyroid cancer risk; however, the findings require confirmation with more accurate exposure models...