T B Harris

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Invited commentary: body composition in studies of aging: new opportunities to better understand health risks associated with weight
    Tamara B Harris
    Geriatric Epidemiology Section, Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, National Institutes of Health, Bethesda, MD 20892 9205, USA
    Am J Epidemiol 156:122-4; discussion 125-6. 2002
  2. ncbi request reprint Aging well and aging poorly: primary and secondary low blood pressure
    Tamara B Harris
    Geriatric Epidemiology Section, Laboratory of Epidemiology, Demography and Biometry, Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland 208792 9205, USA
    J Gerontol A Biol Sci Med Sci 58:662-4; discussion 669-70. 2003
  3. ncbi request reprint Carrying the burden of cardiovascular risk in old age: associations of weight and weight change with prevalent cardiovascular disease, risk factors, and health status in the Cardiovascular Health Study
    T B Harris
    National Institute on Aging, Epidemiology, Demography and Biometry Program, Bethesda, MD 20892 9205, USA
    Am J Clin Nutr 66:837-44. 1997
  4. ncbi request reprint Waist circumference and sagittal diameter reflect total body fat better than visceral fat in older men and women. The Health, Aging and Body Composition Study
    T B Harris
    Epidemiology, Demography and Biometry Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland 20892, USA
    Ann N Y Acad Sci 904:462-73. 2000
  5. ncbi request reprint Body fat and skeletal muscle mass in relation to physical disability in very old men and women of the Framingham Heart Study
    M Visser
    National Institute on Aging, Epidemiology, Demography, and Biometry Program, Bethesda, Maryland, USA
    J Gerontol A Biol Sci Med Sci 53:M214-21. 1998
  6. ncbi request reprint Cross-sectional and prospective relationships of interleukin-6 and C-reactive protein with physical performance in elderly persons: MacArthur studies of successful aging
    D R Taaffe
    The Epidemiology, Demography, and Biometry Program, National Institute on Aging, Bethesda, Maryland 20892 9205, USA
    J Gerontol A Biol Sci Med Sci 55:M709-15. 2000
  7. ncbi request reprint Validity of fan-beam dual-energy X-ray absorptiometry for measuring fat-free mass and leg muscle mass. Health, Aging, and Body Composition Study--Dual-Energy X-ray Absorptiometry and Body Composition Working Group
    M Visser
    Epidemiology, Demography and Biometry Program, National Institute on Aging, Bethesda, Maryland 20892, USA
    J Appl Physiol 87:1513-20. 1999
  8. ncbi request reprint Apo E genotype, diabetes, and peripheral arterial disease in older men: the Honolulu Asia-aging study
    H E Resnick
    Epidemiology, Demography and Biometry Program, National Institute on Aging, Bethesda, Maryland, USA
    Genet Epidemiol 19:52-63. 2000
  9. ncbi request reprint American Diabetes Association diabetes diagnostic criteria, advancing age, and cardiovascular disease risk profiles: results from the Third National Health and Nutrition Examination Survey
    H E Resnick
    Epidemiology, Demography, and Biometry Program, National Institute on Aging, Bethesda, Maryland 20892, USA
    Diabetes Care 23:176-80. 2000
  10. pmc Cohort study of effect of being overweight and change in weight on risk of coronary heart disease in old age
    T B Harris
    Epidemiology, Demography, and Biometry Program, National Institute on Aging, Bethesda, MD, USA
    BMJ 314:1791-4. 1997

Collaborators

Detail Information

Publications77

  1. ncbi request reprint Invited commentary: body composition in studies of aging: new opportunities to better understand health risks associated with weight
    Tamara B Harris
    Geriatric Epidemiology Section, Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, National Institutes of Health, Bethesda, MD 20892 9205, USA
    Am J Epidemiol 156:122-4; discussion 125-6. 2002
    ....
  2. ncbi request reprint Aging well and aging poorly: primary and secondary low blood pressure
    Tamara B Harris
    Geriatric Epidemiology Section, Laboratory of Epidemiology, Demography and Biometry, Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland 208792 9205, USA
    J Gerontol A Biol Sci Med Sci 58:662-4; discussion 669-70. 2003
  3. ncbi request reprint Carrying the burden of cardiovascular risk in old age: associations of weight and weight change with prevalent cardiovascular disease, risk factors, and health status in the Cardiovascular Health Study
    T B Harris
    National Institute on Aging, Epidemiology, Demography and Biometry Program, Bethesda, MD 20892 9205, USA
    Am J Clin Nutr 66:837-44. 1997
    ..Weight stability from age 50 y to old age was associated with better health status than was weight gain or loss...
  4. ncbi request reprint Waist circumference and sagittal diameter reflect total body fat better than visceral fat in older men and women. The Health, Aging and Body Composition Study
    T B Harris
    Epidemiology, Demography and Biometry Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland 20892, USA
    Ann N Y Acad Sci 904:462-73. 2000
    ..40 in women, and 0.49 in men). These data suggest that the contribution of visceral fat to health risks will be better assessed by directly measuring this fat depot...
  5. ncbi request reprint Body fat and skeletal muscle mass in relation to physical disability in very old men and women of the Framingham Heart Study
    M Visser
    National Institute on Aging, Epidemiology, Demography, and Biometry Program, Bethesda, Maryland, USA
    J Gerontol A Biol Sci Med Sci 53:M214-21. 1998
    ..High body weight and high body mass index, both rough indicators of body fatness, have been shown to increase the risk for disability; however, the specific role of body fatness has not been studied...
  6. ncbi request reprint Cross-sectional and prospective relationships of interleukin-6 and C-reactive protein with physical performance in elderly persons: MacArthur studies of successful aging
    D R Taaffe
    The Epidemiology, Demography, and Biometry Program, National Institute on Aging, Bethesda, Maryland 20892 9205, USA
    J Gerontol A Biol Sci Med Sci 55:M709-15. 2000
    ....
  7. ncbi request reprint Validity of fan-beam dual-energy X-ray absorptiometry for measuring fat-free mass and leg muscle mass. Health, Aging, and Body Composition Study--Dual-Energy X-ray Absorptiometry and Body Composition Working Group
    M Visser
    Epidemiology, Demography and Biometry Program, National Institute on Aging, Bethesda, Maryland 20892, USA
    J Appl Physiol 87:1513-20. 1999
    ..86-0.96). MM by DEXA was higher than by CT in three regions. The results of this study suggest that fan-beam DEXA offers considerable promise for the measurement of total body FFM and leg MM in elderly persons...
  8. ncbi request reprint Apo E genotype, diabetes, and peripheral arterial disease in older men: the Honolulu Asia-aging study
    H E Resnick
    Epidemiology, Demography and Biometry Program, National Institute on Aging, Bethesda, Maryland, USA
    Genet Epidemiol 19:52-63. 2000
    ..Further studies are needed to clarify the potential mediating role of diabetes on the apo E-PAD association...
  9. ncbi request reprint American Diabetes Association diabetes diagnostic criteria, advancing age, and cardiovascular disease risk profiles: results from the Third National Health and Nutrition Examination Survey
    H E Resnick
    Epidemiology, Demography, and Biometry Program, National Institute on Aging, Bethesda, Maryland 20892, USA
    Diabetes Care 23:176-80. 2000
    ....
  10. pmc Cohort study of effect of being overweight and change in weight on risk of coronary heart disease in old age
    T B Harris
    Epidemiology, Demography, and Biometry Program, National Institute on Aging, Bethesda, MD, USA
    BMJ 314:1791-4. 1997
    ..To evaluate risk of late life coronary heart disease associated with being overweight in late middle or old age and to assess whether weight change modifies this risk...
  11. ncbi request reprint Race and sex effects on the association between muscle strength, soft tissue, and bone mineral density in healthy elders: the Health, Aging, and Body Composition Study
    D R Taaffe
    Epidemiology, Demography and Biometry Program, National Institute on Aging, Bethesda, Maryland, USA
    J Bone Miner Res 16:1343-52. 2001
    ..Where differences did occur, they were primarily by sex not race. To preserve BMD, maintaining or increasing LM in the elderly would appear to be an appropriate strategy, regardless of race or sex...
  12. ncbi request reprint The role of waist circumference in predicting disability in periretirement age adults
    S B Angleman
    Department of Public Health and Primary Care, Cambridge, UK
    Int J Obes (Lond) 30:364-73. 2006
    ..To measure the risk of periretirement age disability associated with five different anthropometric measures of body mass and shape, and to compare the measures in this group, the peak age group of obesity prevalence...
  13. ncbi request reprint Vitamin E and vitamin C supplement use and risk of all-cause and coronary heart disease mortality in older persons: the Established Populations for Epidemiologic Studies of the Elderly
    K G Losonczy
    Epidemiology, Demography and Biometry Program, National Institute on Aging, Bethesda, MD 20892 9205, USA
    Am J Clin Nutr 64:190-6. 1996
    ..These findings are consistent with those for younger persons and suggest protective effects of vitamin E supplements in the elderly...
  14. pmc Cerebral microbleeds, retinopathy, and dementia: the AGES-Reykjavik Study
    C Qiu
    Laboratory of Epidemiology, Demography and Biometry, National Institute on Aging, Bethesda, MD, USA
    Neurology 75:2221-8. 2010
    ..To determine whether microvascular damage, indicated by cerebral microbleeds (CMBs) and retinal microvascular signs, is associated with cognitive function and dementia in older persons...
  15. ncbi request reprint Cardiovascular disease, interleukin-6, and risk of mortality in older women: the women's health and aging study
    S Volpato
    Epidemiology, Demography, and Biometry Program, National Institute on Aging, Bethesda, MD, USA
    Circulation 103:947-53. 2001
    ..We investigated whether specific chronic conditions, particularly cardiovascular disease (CVD), affect the association between high interleukin (IL)-6 level and mortality in a sample of disabled older women...
  16. ncbi request reprint Change in muscle mass and muscle strength after a hip fracture: relationship to mobility recovery
    M Visser
    Epidemiology, Demography and Biometry Program, National Institute on Aging, Bethesda, Maryland, USA
    J Gerontol A Biol Sci Med Sci 55:M434-40. 2000
    ..Hip fracture in elderly persons has a serious impact on long-term physical function. This study determines the change in muscle strength and muscle mass after a hip fracture, and the associations between these changes and mobility recovery...
  17. ncbi request reprint The value of serum albumin and high-density lipoprotein cholesterol in defining mortality risk in older persons with low serum cholesterol
    S Volpato
    Epidemiology, Demography and Biometry Program, National Institute on Aging, Bethesda, Maryland 20892, USA
    J Am Geriatr Soc 49:1142-7. 2001
    ....
  18. pmc Racial variation in the relationship of anemia with mortality and mobility disability among older adults
    Kushang V Patel
    Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging NIH, Bethesda, MD 20892, USA
    Blood 109:4663-70. 2007
    ..Conversely, older blacks classified as anemic by WHO criteria were not at risk for adverse events, indicating that alternative criteria are warranted...
  19. ncbi request reprint Diabetes, inflammation, and functional decline in older adults: findings from the Health, Aging and Body Composition (ABC) study
    M Kathleen Figaro
    Department of Medicine, Vanderbilt University Medical Center GRECC, 1310 24th Ave South, Room 4B111, Nashville, TN 37212, USA
    Diabetes Care 29:2039-45. 2006
    ..We examined the effect of C-reactive protein (CRP) and interleukin-6 (IL-6) on the incident mobility limitation in older adults with and without diabetes...
  20. ncbi request reprint Overweight, obesity, and mortality in a large prospective cohort of persons 50 to 71 years old
    Kenneth F Adams
    Nutritional Epidemiology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    N Engl J Med 355:763-78. 2006
    ..0 or more, is associated with an increased risk of death, but the relation between overweight (a BMI of 25.0 to 29.9) and the risk of death has been questioned...
  21. pmc Limited literacy and mortality in the elderly: the health, aging, and body composition study
    Rebecca L Sudore
    University of California, San Francisco, CA 94121, USA
    J Gen Intern Med 21:806-12. 2006
    ..While limited literacy is common and its prevalence increases with age, no prospective study has assessed whether limited literacy is associated with mortality in older adults...
  22. ncbi request reprint Diabetes, hyperglycemia, and inflammation in older individuals: the health, aging and body composition study
    Nathalie de Rekeneire
    Laboratory of Epidemiology, National Institute on Aging, Bethesda, MD 20892 9205, USA
    Diabetes Care 29:1902-8. 2006
    ..The objective of this study was to assess the association of inflammation with hyperglycemia (impaired fasting glucose [IFG]/impaired glucose tolerance [IGT]) and diabetes in older individuals...
  23. ncbi request reprint Impact of inflammation on the relationship among alcohol consumption, mortality, and cardiac events: the health, aging, and body composition study
    Cinzia Maraldi
    Department of Aging and Geriatric Research, College of Medicine, Institute on Aging, University of Florida, 1329 SW 16th St, Gainesville, FL 32608, USA
    Arch Intern Med 166:1490-7. 2006
    ..We investigated the relationship of alcohol intake with all-cause mortality and cardiac events and evaluated whether this relationship is mediated or modified by inflammatory markers...
  24. ncbi request reprint Daily activity energy expenditure and mortality among older adults
    Todd M Manini
    National Institute on Aging, Laboratory of Epidemiology, Demography and Biometry, Bethesda, MD 20892, USA
    JAMA 296:171-9. 2006
    ..Exercise is associated with mortality benefits but simply expending energy through any activity in an individual's free-living environment may confer survival advantages...
  25. ncbi request reprint Renal function and heart failure risk in older black and white individuals: the Health, Aging, and Body Composition Study
    Kirsten Bibbins-Domingo
    Division of General Internal Medicine, San Francisco General Hospital, CA 94143 1364, USA
    Arch Intern Med 166:1396-402. 2006
    ..Our objective was to determine whether the association of chronic kidney disease with incident heart failure differs between blacks and whites...
  26. ncbi request reprint Limited literacy in older people and disparities in health and healthcare access
    Rebecca L Sudore
    Department of Medicine, Division of Geriatrics, University of California San Francisco, San Francisco, CA, USA
    J Am Geriatr Soc 54:770-6. 2006
    ..To determine the relationship between health literacy, demographics, and access to health care...
  27. ncbi request reprint Association of long-distance corridor walk performance with mortality, cardiovascular disease, mobility limitation, and disability
    Anne B Newman
    Department of Epidemiology, Physical Therapy, University of Pittsburgh, Pittsburgh, PA 15213, USA
    JAMA 295:2018-26. 2006
    ..Extended walking tests have been examined as outcome predictors in medically ill populations but not in community-dwelling older adults...
  28. ncbi request reprint Metabolic syndrome and the risk of cardiovascular disease in older adults
    Javed Butler
    Division of Cardiovascular Medicine, Vanderbilt University, Nashville, Tennessee, USA
    J Am Coll Cardiol 47:1595-602. 2006
    ..The purpose of this study was to assess whether metabolic syndrome (MetSyn) predicts a higher risk for cardiovascular events in older adults...
  29. pmc Thiazolidinedione use and bone loss in older diabetic adults
    Ann V Schwartz
    Department of Epidemiology and Biostatistics, University of California, San Francisco, 185 Berry Street, Lobby 4, Suite 5700, San Francisco, California 94107 1762, USA
    J Clin Endocrinol Metab 91:3349-54. 2006
    ..Activation of peroxisome proliferator-activated receptor-gamma by thiazolidinediones (TZDs) results in lower bone mass in mice...
  30. pmc Age, Gene/Environment Susceptibility-Reykjavik Study: multidisciplinary applied phenomics
    Tamara B Harris
    Laboratory of Epidemiology, Demography, and Biometry, Intramural Research Program, National Institute on Aging, Bethesda, MD 20892 9205, USA
    Am J Epidemiol 165:1076-87. 2007
    ..This approach should facilitate identification of genetic factors that contribute to healthy aging as well as the chronic conditions common in old age...
  31. ncbi request reprint Multitasking: association between poorer performance and a history of recurrent falls
    Kimberly A Faulkner
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    J Am Geriatr Soc 55:570-6. 2007
    ..To examine the association between poorer performance on concurrent walking and reaction time and recurrent falls...
  32. ncbi request reprint Body mass index and serum leptin concentration independently estimate percentage body fat in older adults
    Constance E Ruhl
    Social and Scientific Systems Inc, Silver Spring, MD, USA
    Am J Clin Nutr 85:1121-6. 2007
    ....
  33. pmc Cognitive impairment: an increasingly important complication of type 2 diabetes: the age, gene/environment susceptibility--Reykjavik study
    Jane S Saczynski
    Division of Geriatric Medicine, University of Massachusetts Medical School, Biotech Four, Suite 315, 377 Plantation Street, Worcester, MA 01605, USA
    Am J Epidemiol 168:1132-9. 2008
    ..01) and poorer memory performance (beta = -0.22; P < 0.05). Persons with type 2 diabetes have poorer cognitive performance than normoglycemics, particularly in PS. Those with undiagnosed diabetes have the lowest cognitive performance...
  34. pmc Fetuin-A and incident diabetes mellitus in older persons
    Joachim H Ix
    Division of Nephrology and Hypertension, Department of Medicine, University of California, San Diego, and San Diego Veterans Affairs Healthcare System, 3350 La Jolla Village Dr, Mail Code 111 H, San Diego, CA 92161, USA
    JAMA 300:182-8. 2008
    ..In prior cross-sectional studies in humans, higher fetuin-A levels were associated with insulin resistance. However, the longitudinal association of fetuin-A with incident type 2 diabetes mellitus is unknown...
  35. doi request reprint The association of pericardial fat with calcified coronary plaque
    Jingzhong Ding
    Sticht Center on Aging, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    Obesity (Silver Spring) 16:1914-9. 2008
    ..Pericardial fat has a higher secretion of inflammatory cytokines than subcutaneous fat. Cytokines released from pericardial fat around coronary arteries may act locally on the adjacent cells...
  36. pmc The relationship of reduced peripheral nerve function and diabetes with physical performance in older white and black adults: the Health, Aging, and Body Composition (Health ABC) study
    Elsa S Strotmeyer
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Diabetes Care 31:1767-72. 2008
    ..Poor peripheral nerve function is prevalent in diabetes and older populations, and it has great potential to contribute to poor physical performance...
  37. doi request reprint Waist circumference and mortality
    Annemarie Koster
    Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Bethesda, MD 20892, USA
    Am J Epidemiol 167:1465-75. 2008
    ..36). The finding that persons with a normal BMI but a large waist circumference had a higher mortality risk in this study suggests that increased waist circumference should be considered a risk factor for mortality, in addition to BMI...
  38. doi request reprint Hemodynamics of increased pulse pressure in older women in the community-based Age, Gene/Environment Susceptibility-Reykjavik Study
    Gary F Mitchell
    Cardiovascular Engineering Inc, 51 Sawyer Road, Suite 100, Waltham, MA 02453, USA
    Hypertension 51:1123-8. 2008
    ..4+/-1.4 mm Hg, P=0.75). Thus, reduced aortic diameter and impaired matching between diameter and flow accounts for the sex difference in pulse pressure in an unselected community-based cohort of older people...
  39. pmc Dietary glycemic index and glycemic load and the risk of type 2 diabetes in older adults
    Nadine R Sahyoun
    Department of Nutrition and Food Science, University of Maryland, College Park, MD 20742, USA
    Am J Clin Nutr 87:126-31. 2008
    ..It is unclear whether immediate dietary effects on blood glucose influence the risk of developing type 2 diabetes...
  40. ncbi request reprint Kidney dysfunction and fatal cardiovascular disease--an association independent of atherosclerotic events: results from the Health, Aging, and Body Composition (Health ABC) study
    Rajat Deo
    Division of Cardiology, Johns Hopkins Hospital, Baltimore, MD, USA
    Am Heart J 155:62-8. 2008
    ..We evaluated whether impaired kidney function predicted risk of fatal cardiovascular disease independent of prevalent and incident cardiovascular events...
  41. pmc Diabetes-related complications, glycemic control, and falls in older adults
    Ann V Schwartz
    Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California 94107 1762, USA
    Diabetes Care 31:391-6. 2008
    ..We determined whether diabetes-related complications or treatments are associated with risk of falls in older diabetic adults...
  42. ncbi request reprint Kidney function as a predictor of loss of lean mass in older adults: health, aging and body composition study
    Linda F Fried
    Renal Section, Veterans Affairs Pittsburgh Healthcare System Pittsburgh, Pennsylvania 15240, USA
    J Am Geriatr Soc 55:1578-84. 2007
    ..To assess the association between kidney function and change in body composition in older individuals...
  43. ncbi request reprint Factors associated with impaired appetite in well-functioning community-dwelling older adults
    Jung Sun Lee
    Department of Foods and Nutrition, University of Georgia, Athens, GA 30602, USA
    J Nutr Elder 26:27-43. 2006
    ..5 (1.6- 4.1)), poor self-reported health (2.4 (1.7-3.2)), current smoking, chewing problems, reported visual impairment, weight loss since age 50, and log (TNF-alpha) were significantly related to impaired appetite...
  44. ncbi request reprint Psychosocial risk factors and the metabolic syndrome in elderly persons: findings from the Health, Aging and Body Composition study
    Nicole Vogelzangs
    Department of Psychiatry and Institute for Research in Extramural Medicine, VU University Medical Center, Amsterdam, The Netherlands
    J Gerontol A Biol Sci Med Sci 62:563-9. 2007
    ..This study investigated the cross-sectional relationship between psychosocial risk factors and the metabolic syndrome in a community-based sample of older persons...
  45. ncbi request reprint Inflammatory markers and incident fracture risk in older men and women: the Health Aging and Body Composition Study
    Jane A Cauley
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    J Bone Miner Res 22:1088-95. 2007
    ..We tested this hypothesis in relationship to fractures in 2985 men and women enrolled in the Health ABC study. Results showed that subjects with the greatest number of inflammatory markers have the highest risk of fracture...
  46. ncbi request reprint Reduced peripheral nerve function is related to lower hip BMD and calcaneal QUS in older white and black adults: the Health, Aging, and Body Composition Study
    Elsa S Strotmeyer
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    J Bone Miner Res 21:1803-10. 2006
    ..Poor peripheral nerve function may directly affect bone...
  47. ncbi request reprint Adipocytokines and incident diabetes mellitus in older adults: the independent effect of plasminogen activator inhibitor 1
    Alka M Kanaya
    Division of General Internal Medicine, Department of Medicine, University of California, San Francisco, Suite 500, San Francisco, CA 94143 1732, USA
    Arch Intern Med 166:350-6. 2006
    ..Adipose tissue produces "adipocytokines" of uncertain clinical significance...
  48. ncbi request reprint Aspirin use for the primary prevention of coronary heart disease in older adults
    Nicolas Rodondi
    Department of Epidemiology and Biostatistics, University of California, San Francisco, Calif, USA
    Am J Med 118:1288. 2005
    ..We determined the prevalence of aspirin use in relation to coronary heart disease risk and changes over time...
  49. ncbi request reprint Physical activity, exercise, and inflammatory markers in older adults: findings from the Health, Aging and Body Composition Study
    Lisa H Colbert
    Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Bethesda, Maryland, USA
    J Am Geriatr Soc 52:1098-104. 2004
    ..To examine the association between physical activity and inflammatory markers, with consideration for body fatness and antioxidant use...
  50. ncbi request reprint Diabetes is associated independently of body composition with BMD and bone volume in older white and black men and women: The Health, Aging, and Body Composition Study
    Elsa S Strotmeyer
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    J Bone Miner Res 19:1084-91. 2004
    ..Diabetes predicted higher hip, whole body, and volumetric spine BMD, and lower spine bone volume, independent of body composition and fasting insulin...
  51. ncbi request reprint Cholesterol and health in old age: risk factor or risk marker?
    Tamara B Harris
    J Am Geriatr Soc 52:639-40. 2004
  52. ncbi request reprint Energy requirements in the eighth decade of life
    Stephane Blanc
    University of Wisconsin Madison, WI 53706, USA
    Am J Clin Nutr 79:303-10. 2004
    ..Knowledge of energy requirements among relatively healthy elderly is limited...
  53. ncbi request reprint Edentulism and nutritional status in a biracial sample of well-functioning, community-dwelling elderly: the health, aging, and body composition study
    Jung Sun Lee
    Division of Geriatric Medicine, University of Pittsburgh, PA 15213, USA
    Am J Clin Nutr 79:295-302. 2004
    ..Edentulism may affect dietary intake in older adults, but the relation between edentulism and nutritional status is not completely understood...
  54. ncbi request reprint Alcohol intake and cerebral abnormalities on magnetic resonance imaging in a community-based population of middle-aged adults: the Atherosclerosis Risk in Communities (ARIC) study
    Jingzhong Ding
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe St, Room 6009, Baltimore, MD 21205, USA
    Stroke 35:16-21. 2004
    ..We examined the associations of alcohol intake with MRI-defined cerebral abnormalities in a middle-aged, population-based cohort...
  55. ncbi request reprint Diabetes is associated with subclinical functional limitation in nondisabled older individuals: the Health, Aging, and Body Composition study
    Nathalie de Rekeneire
    Laboratory of Epidemiology, Demography and Biometry, National Institute on Aging, Bethesda, Maryland, USA
    Diabetes Care 26:3257-63. 2003
    ....
  56. ncbi request reprint Neck and shoulder pain in 70- to 79-year-old men and women: findings from the Health, Aging and Body Composition Study
    Molly T Vogt
    Department of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Spine J 3:435-41. 2003
    ..Musculoskeletal pain in the cervicobrachial region is considered a major health problem among adults of working age, but little is known about the impact of this pain in the elderly...
  57. ncbi request reprint Racial differences in glycemic control in a well-functioning older diabetic population: findings from the Health, Aging and Body Composition Study
    Nathalie de Rekeneire
    Laboratory of Epidemiology, Demography and Biometry, National Institute on Aging, National Institutes of Health, Bethesda, Maryland 20892 9205, USA
    Diabetes Care 26:1986-92. 2003
    ..We further hypothesized that the association of race with poorer glycemic control would be limited to those with lower education or lower income...
  58. ncbi request reprint One- and two-year change in body composition as measured by DXA in a population-based cohort of older men and women
    Marjolein Visser
    Institute for Research in Extramural Medicine, Vrije University Medical Center, 1081 BT Amsterdam, The Netherlands
    J Appl Physiol 94:2368-74. 2003
    ..Loss of ALST was greater in men compared with women, and greater in blacks compared with whites, suggesting that men and blacks may be more prone to muscle loss...
  59. ncbi request reprint Association between regional adipose tissue distribution and both type 2 diabetes and impaired glucose tolerance in elderly men and women
    Bret H Goodpaster
    Department of Medicine, University of Pittsburgh Medical Center, Pennsylvania 15213, USA
    Diabetes Care 26:372-9. 2003
    ....
  60. ncbi request reprint Change in muscle strength explains accelerated decline of physical function in older women with high interleukin-6 serum levels
    Luigi Ferrucci
    Laboratory of Clinical Epidemiology, INRCA Geriatric Department, Florence, Italy
    J Am Geriatr Soc 50:1947-54. 2002
    ..To test whether accelerated sarcopenia in older persons with high interleukin (IL)-6 serum levels plays a role in the prospective association between inflammation and disability found in many studies...
  61. ncbi request reprint Leg muscle mass and composition in relation to lower extremity performance in men and women aged 70 to 79: the health, aging and body composition study
    Marjolein Visser
    Institute for Research in Extramural Medicine, Faculty of Medicine, Vrije Universiteit, Amsterdam, The Netherlands
    J Am Geriatr Soc 50:897-904. 2002
    ..Our aim was to determine whether low leg muscle mass and greater fat infiltration in the muscle were associated with poor lower extremity performance (LEP)...
  62. ncbi request reprint Serum leptin concentrations and body adipose measures in older black and white adults
    Constance E Ruhl
    Social and Scientific Systems, Inc, 8758 Georgia Avenue, Silver Spring, MD 20910, USA
    Am J Clin Nutr 80:576-83. 2004
    ..Among US adults, serum leptin concentrations are higher in women than in men and are higher in blacks than in whites independent of anthropometric measures of body fatness...
  63. ncbi request reprint Association between physical and cognitive function in healthy elderly: the health, aging and body composition study
    Caterina Rosano
    Department of Medicine, Division of Geriatric Medicine, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Neuroepidemiology 24:8-14. 2005
    ..Longitudinal studies are needed to determine the direction of causality in this relationship...
  64. ncbi request reprint Cystatin C and mortality risk in the elderly: the health, aging, and body composition study
    Michael G Shlipak
    University of San Francisco, General Internal Medicine Section, VA Medical Center 111A1, 4150 Clement Street, San Francisco, CA 94121, USA
    J Am Soc Nephrol 17:254-61. 2006
    ..39], 0.95 [0.68 to 1.32], 1.11 [0.79 to 1.57], 1.16 [0.86 to 1.58]). Cystatin C is a strong, independent risk factor for mortality in the elderly. Future studies should investigate whether cystatin C has a role in clinical medicine...
  65. ncbi request reprint Lipoprotein peroxidation and mobility limitation: results from the Health, Aging, and Body Composition Study
    Matteo Cesari
    Department of Aging and Geriatric Research, College of Medicine, Institute on Aging, University of Florida, Gainesville 32608, USA
    Arch Intern Med 165:2148-54. 2005
    ..The aim of this study was to assess the predictive value of a lipoprotein peroxidation marker, oxidized low-density lipoprotein (oxLDL) for incident mobility limitation (ML)...
  66. ncbi request reprint Weight change and the conservation of lean mass in old age: the Health, Aging and Body Composition Study
    Anne B Newman
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Am J Clin Nutr 82:872-8; quiz 915-6. 2005
    ..Weight loss may contribute to the loss of lean mass with age...
  67. ncbi request reprint Dietary glycemic index and load, measures of glucose metabolism, and body fat distribution in older adults
    Nadine R Sahyoun
    Department of Nutrition and Food Science, University of Maryland, College Park, MD 20742, USA
    Am J Clin Nutr 82:547-52. 2005
    ..Recent evidence suggests that the rate of carbohydrate digestion and absorption may influence the development of type 2 diabetes...
  68. ncbi request reprint Is there a biomedical explanation for socioeconomic differences in incident mobility limitation?
    Annemarie Koster
    Department of Health Care Studies, Section Medical Sociology, Universiteit Maastricht, Maastricht, The Netherlands
    J Gerontol A Biol Sci Med Sci 60:1022-7. 2005
    ..This study examines the association between socioeconomic status and incident mobility limitation in well-functioning older adults, and seeks to determine whether this link could be explained by biomedical factors...
  69. ncbi request reprint Cross-sectional associations between trunk muscle composition, back pain, and physical function in the health, aging and body composition study
    Gregory E Hicks
    Clinical Research Branch, National Institute on Aging, Baltimore, MD 21201, USA
    J Gerontol A Biol Sci Med Sci 60:882-7. 2005
    ..We hypothesized that lower trunk muscle area and attenuation (higher fat infiltration) are associated with decreased functional capacity...
  70. ncbi request reprint Muscle mass, muscle strength, and muscle fat infiltration as predictors of incident mobility limitations in well-functioning older persons
    Marjolein Visser
    Institute for Research in Extramural Medicine, VU University Medical Center, Van der Boechorststraat 7, 1081 BT Amsterdam, The Netherlands
    J Gerontol A Biol Sci Med Sci 60:324-33. 2005
    ..This study aims to investigate whether low muscle mass, low muscle strength, and greater fat infiltration into the muscle predict incident mobility limitation...
  71. ncbi request reprint Obesity, regional body fat distribution, and the metabolic syndrome in older men and women
    Bret H Goodpaster
    Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Arch Intern Med 165:777-83. 2005
    ..We determined whether patterns of regional fat deposition are associated with metabolic syndrome in older adults...
  72. pmc Adipose tissue in muscle: a novel depot similar in size to visceral adipose tissue
    Dympna Gallagher
    Department of Medicine, Obesity Research Center, St Luke s Roosevelt Hospital, New York, NY, USA
    Am J Clin Nutr 81:903-10. 2005
    ..The manner in which fat depot volumes and distributions, particularly the adipose tissue (AT) between the muscles, vary by race is unknown...
  73. ncbi request reprint Diabetes and bone loss at the hip in older black and white adults
    Ann V Schwartz
    Department of Epidemiology and Biostatistics, University of California, San Francisco, California 94105, USA
    J Bone Miner Res 20:596-603. 2005
    ....
  74. pmc Population structure, admixture, and aging-related phenotypes in African American adults: the Cardiovascular Health Study
    Alexander P Reiner
    Department of Epidemiology, University of Washington, Seattle, WA 98101 1448, USA
    Am J Hum Genet 76:463-77. 2005
    ..Complementary methods that identify discrete subgroups on the basis of genetic similarity may help to further characterize the complex biodemographic structure of human populations...
  75. ncbi request reprint The association of regional fat depots with hypertension in older persons of white and African American ethnicity
    Jingzhong Ding
    Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, USA
    Am J Hypertens 17:971-6. 2004
    ..Fat distribution has been shown to be a strong correlate of hypertension, independent of general obesity. However, population-based studies are lacking on the association of regional fat depots with hypertension...
  76. ncbi request reprint Association of visceral adipose tissue with incident myocardial infarction in older men and women: the Health, Aging and Body Composition Study
    Barbara J Nicklas
    Section on Gerontology and Geriatric Medicine, Sticht Center on Aging, Wake Forest University School of Medicine, Winston Salem, NC, USA
    Am J Epidemiol 160:741-9. 2004
    ..79, 95% confidence interval: 1.24, 2.58 per standard-deviation increase; p < 0.01). The amount of adipose tissue stored in the intraabdominal cavity is an important, independent risk factor for MI in well-functioning, elderly women...
  77. ncbi request reprint Peripheral blood markers of inflammation predict mortality and functional decline in high-functioning community-dwelling older persons
    David B Reuben
    Multicampus Program in Geriatric Medicine and Gerontology, UCLA School of Medicine, Los Angeles, California 90095, USA
    J Am Geriatr Soc 50:638-44. 2002
    ..The objective of this study was to determine the prognostic value of combining four peripheral blood measures of inflammation in healthy older persons...