Research Topics
| T B HarrisSummaryAffiliation: National Institutes of Health Country: USA Publications
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Publications
Invited commentary: body composition in studies of aging: new opportunities to better understand health risks associated with weightTamara B Harris
Geriatric Epidemiology Section, Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, National Institutes of Health, Bethesda, MD 20892 9205, USA
Am J Epidemiol 156:122-4; discussion 125-6. 2002....
Aging well and aging poorly: primary and secondary low blood pressureTamara B Harris
Geriatric Epidemiology Section, Laboratory of Epidemiology, Demography and Biometry, Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland 208792-9205, USA
J Gerontol A Biol Sci Med Sci 58:662-4; discussion 669-70. 2003
Carrying the burden of cardiovascular risk in old age: associations of weight and weight change with prevalent cardiovascular disease, risk factors, and health status in the Cardiovascular Health StudyT B Harris
National Institute on Aging, Epidemiology, Demography and Biometry Program, Bethesda, MD 20892 9205, USA
Am J Clin Nutr 66:837-44. 1997..Weight stability from age 50 y to old age was associated with better health status than was weight gain or loss...
Waist circumference and sagittal diameter reflect total body fat better than visceral fat in older men and women. The Health, Aging and Body Composition StudyT B Harris
Epidemiology, Demography and Biometry Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland 20892, USA
Ann N Y Acad Sci 904:462-73. 2000..40 in women, and 0.49 in men). These data suggest that the contribution of visceral fat to health risks will be better assessed by directly measuring this fat depot...
Body fat and skeletal muscle mass in relation to physical disability in very old men and women of the Framingham Heart StudyM Visser
National Institute on Aging, Epidemiology, Demography, and Biometry Program, Bethesda, Maryland, USA
J Gerontol A Biol Sci Med Sci 53:M214-21. 1998..High body weight and high body mass index, both rough indicators of body fatness, have been shown to increase the risk for disability; however, the specific role of body fatness has not been studied...
Cross-sectional and prospective relationships of interleukin-6 and C-reactive protein with physical performance in elderly persons: MacArthur studies of successful agingD R Taaffe
The Epidemiology, Demography, and Biometry Program, National Institute on Aging, Bethesda, Maryland 20892 9205, USA
J Gerontol A Biol Sci Med Sci 55:M709-15. 2000....
Validity of fan-beam dual-energy X-ray absorptiometry for measuring fat-free mass and leg muscle mass. Health, Aging, and Body Composition Study--Dual-Energy X-ray Absorptiometry and Body Composition Working GroupM Visser
Epidemiology, Demography and Biometry Program, National Institute on Aging, Bethesda, Maryland 20892, USA
J Appl Physiol 87:1513-20. 1999..86-0.96). MM by DEXA was higher than by CT in three regions. The results of this study suggest that fan-beam DEXA offers considerable promise for the measurement of total body FFM and leg MM in elderly persons...
Apo E genotype, diabetes, and peripheral arterial disease in older men: the Honolulu Asia-aging studyH E Resnick
Epidemiology, Demography and Biometry Program, National Institute on Aging, Bethesda, Maryland, USA
Genet Epidemiol 19:52-63. 2000..Further studies are needed to clarify the potential mediating role of diabetes on the apo E-PAD association...
American Diabetes Association diabetes diagnostic criteria, advancing age, and cardiovascular disease risk profiles: results from the Third National Health and Nutrition Examination SurveyH E Resnick
Epidemiology, Demography, and Biometry Program, National Institute on Aging, Bethesda, Maryland 20892, USA
Diabetes Care 23:176-80. 2000....
Cohort study of effect of being overweight and change in weight on risk of coronary heart disease in old ageT B Harris
Epidemiology, Demography, and Biometry Program, National Institute on Aging, Bethesda, MD, USA
BMJ 314:1791-4. 1997..To evaluate risk of late life coronary heart disease associated with being overweight in late middle or old age and to assess whether weight change modifies this risk...
Race and sex effects on the association between muscle strength, soft tissue, and bone mineral density in healthy elders: the Health, Aging, and Body Composition StudyD R Taaffe
Epidemiology, Demography and Biometry Program, National Institute on Aging, Bethesda, Maryland, USA
J Bone Miner Res 16:1343-52. 2001..Where differences did occur, they were primarily by sex not race. To preserve BMD, maintaining or increasing LM in the elderly would appear to be an appropriate strategy, regardless of race or sex...
The role of waist circumference in predicting disability in periretirement age adultsS B Angleman
Department of Public Health and Primary Care, Cambridge, UK
Int J Obes (Lond) 30:364-73. 2006..To measure the risk of periretirement age disability associated with five different anthropometric measures of body mass and shape, and to compare the measures in this group, the peak age group of obesity prevalence...
Vitamin E and vitamin C supplement use and risk of all-cause and coronary heart disease mortality in older persons: the Established Populations for Epidemiologic Studies of the ElderlyK G Losonczy
Epidemiology, Demography and Biometry Program, National Institute on Aging, Bethesda, MD 20892 9205, USA
Am J Clin Nutr 64:190-6. 1996..These findings are consistent with those for younger persons and suggest protective effects of vitamin E supplements in the elderly...
Cerebral microbleeds, retinopathy, and dementia: the AGES-Reykjavik StudyC Qiu
Laboratory of Epidemiology, Demography and Biometry, National Institute on Aging, Bethesda, MD, USA
Neurology 75:2221-8. 2010..To determine whether microvascular damage, indicated by cerebral microbleeds (CMBs) and retinal microvascular signs, is associated with cognitive function and dementia in older persons...
Cardiovascular disease, interleukin-6, and risk of mortality in older women: the women's health and aging studyS Volpato
Epidemiology, Demography, and Biometry Program, National Institute on Aging, Bethesda, MD, USA
Circulation 103:947-53. 2001..We investigated whether specific chronic conditions, particularly cardiovascular disease (CVD), affect the association between high interleukin (IL)-6 level and mortality in a sample of disabled older women...
Change in muscle mass and muscle strength after a hip fracture: relationship to mobility recoveryM Visser
Epidemiology, Demography and Biometry Program, National Institute on Aging, Bethesda, Maryland, USA
J Gerontol A Biol Sci Med Sci 55:M434-40. 2000..Hip fracture in elderly persons has a serious impact on long-term physical function. This study determines the change in muscle strength and muscle mass after a hip fracture, and the associations between these changes and mobility recovery...
The value of serum albumin and high-density lipoprotein cholesterol in defining mortality risk in older persons with low serum cholesterolS Volpato
Epidemiology, Demography and Biometry Program, National Institute on Aging, Bethesda, Maryland 20892, USA
J Am Geriatr Soc 49:1142-7. 2001....
Racial variation in the relationship of anemia with mortality and mobility disability among older adultsKushang V Patel
Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging NIH, Bethesda, MD 20892, USA
Blood 109:4663-70. 2007..Conversely, older blacks classified as anemic by WHO criteria were not at risk for adverse events, indicating that alternative criteria are warranted...
Diabetes, inflammation, and functional decline in older adults: findings from the Health, Aging and Body Composition (ABC) studyM Kathleen Figaro
Department of Medicine, Vanderbilt University Medical Center GRECC, 1310 24th Ave South, Room 4B111, Nashville, TN 37212, USA
Diabetes Care 29:2039-45. 2006..We examined the effect of C-reactive protein (CRP) and interleukin-6 (IL-6) on the incident mobility limitation in older adults with and without diabetes...
Overweight, obesity, and mortality in a large prospective cohort of persons 50 to 71 years oldKenneth F Adams
Nutritional Epidemiology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
N Engl J Med 355:763-78. 2006..0 or more, is associated with an increased risk of death, but the relation between overweight (a BMI of 25.0 to 29.9) and the risk of death has been questioned...
Limited literacy and mortality in the elderly: the health, aging, and body composition studyRebecca L Sudore
University of California, San Francisco, CA 94121, USA
J Gen Intern Med 21:806-12. 2006..While limited literacy is common and its prevalence increases with age, no prospective study has assessed whether limited literacy is associated with mortality in older adults...
Diabetes, hyperglycemia, and inflammation in older individuals: the health, aging and body composition studyNathalie de Rekeneire
Laboratory of Epidemiology, National Institute on Aging, Bethesda, MD 20892 9205, USA
Diabetes Care 29:1902-8. 2006..The objective of this study was to assess the association of inflammation with hyperglycemia (impaired fasting glucose [IFG]/impaired glucose tolerance [IGT]) and diabetes in older individuals...
Impact of inflammation on the relationship among alcohol consumption, mortality, and cardiac events: the health, aging, and body composition studyCinzia Maraldi
Department of Aging and Geriatric Research, College of Medicine, Institute on Aging, University of Florida, 1329 SW 16th St, Gainesville, FL 32608, USA
Arch Intern Med 166:1490-7. 2006..We investigated the relationship of alcohol intake with all-cause mortality and cardiac events and evaluated whether this relationship is mediated or modified by inflammatory markers...
Daily activity energy expenditure and mortality among older adultsTodd M Manini
National Institute on Aging, Laboratory of Epidemiology, Demography and Biometry, Bethesda, MD 20892, USA
JAMA 296:171-9. 2006..Exercise is associated with mortality benefits but simply expending energy through any activity in an individual's free-living environment may confer survival advantages...
Renal function and heart failure risk in older black and white individuals: the Health, Aging, and Body Composition StudyKirsten Bibbins-Domingo
Division of General Internal Medicine, San Francisco General Hospital, CA 94143 1364, USA
Arch Intern Med 166:1396-402. 2006..Our objective was to determine whether the association of chronic kidney disease with incident heart failure differs between blacks and whites...
Limited literacy in older people and disparities in health and healthcare accessRebecca L Sudore
Department of Medicine, Division of Geriatrics, University of California San Francisco, San Francisco, CA, USA
J Am Geriatr Soc 54:770-6. 2006..To determine the relationship between health literacy, demographics, and access to health care...
Association of long-distance corridor walk performance with mortality, cardiovascular disease, mobility limitation, and disabilityAnne B Newman
Department of Epidemiology, Physical Therapy, University of Pittsburgh, Pittsburgh, PA 15213, USA
JAMA 295:2018-26. 2006..Extended walking tests have been examined as outcome predictors in medically ill populations but not in community-dwelling older adults...
Metabolic syndrome and the risk of cardiovascular disease in older adultsJaved Butler
Division of Cardiovascular Medicine, Vanderbilt University, Nashville, Tennessee, USA
J Am Coll Cardiol 47:1595-602. 2006..The purpose of this study was to assess whether metabolic syndrome (MetSyn) predicts a higher risk for cardiovascular events in older adults...
Thiazolidinedione use and bone loss in older diabetic adultsAnn V Schwartz
Department of Epidemiology and Biostatistics, University of California, San Francisco, 185 Berry Street, Lobby 4, Suite 5700, San Francisco, California 94107 1762, USA
J Clin Endocrinol Metab 91:3349-54. 2006..Activation of peroxisome proliferator-activated receptor-gamma by thiazolidinediones (TZDs) results in lower bone mass in mice...
Age, Gene/Environment Susceptibility-Reykjavik Study: multidisciplinary applied phenomicsTamara B Harris
Laboratory of Epidemiology, Demography, and Biometry, Intramural Research Program, National Institute on Aging, Bethesda, MD 20892 9205, USA
Am J Epidemiol 165:1076-87. 2007..This approach should facilitate identification of genetic factors that contribute to healthy aging as well as the chronic conditions common in old age...
Multitasking: association between poorer performance and a history of recurrent fallsKimberly A Faulkner
Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
J Am Geriatr Soc 55:570-6. 2007..To examine the association between poorer performance on concurrent walking and reaction time and recurrent falls...
Body mass index and serum leptin concentration independently estimate percentage body fat in older adultsConstance E Ruhl
Social and Scientific Systems Inc, Silver Spring, MD, USA
Am J Clin Nutr 85:1121-6. 2007....
Cognitive impairment: an increasingly important complication of type 2 diabetes: the age, gene/environment susceptibility--Reykjavik studyJane S Saczynski
Division of Geriatric Medicine, University of Massachusetts Medical School, Biotech Four, Suite 315, 377 Plantation Street, Worcester, MA 01605, USA
Am J Epidemiol 168:1132-9. 2008..01) and poorer memory performance (beta = -0.22; P < 0.05). Persons with type 2 diabetes have poorer cognitive performance than normoglycemics, particularly in PS. Those with undiagnosed diabetes have the lowest cognitive performance...
Fetuin-A and incident diabetes mellitus in older personsJoachim H Ix
Division of Nephrology and Hypertension, Department of Medicine, University of California, San Diego, and San Diego Veterans Affairs Healthcare System, 3350 La Jolla Village Dr, Mail Code 111 H, San Diego, CA 92161, USA
JAMA 300:182-8. 2008..In prior cross-sectional studies in humans, higher fetuin-A levels were associated with insulin resistance. However, the longitudinal association of fetuin-A with incident type 2 diabetes mellitus is unknown...
The association of pericardial fat with calcified coronary plaqueJingzhong Ding
Sticht Center on Aging, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
Obesity (Silver Spring) 16:1914-9. 2008..Pericardial fat has a higher secretion of inflammatory cytokines than subcutaneous fat. Cytokines released from pericardial fat around coronary arteries may act locally on the adjacent cells...
The relationship of reduced peripheral nerve function and diabetes with physical performance in older white and black adults: the Health, Aging, and Body Composition (Health ABC) studyElsa S Strotmeyer
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Diabetes Care 31:1767-72. 2008..Poor peripheral nerve function is prevalent in diabetes and older populations, and it has great potential to contribute to poor physical performance...
Waist circumference and mortalityAnnemarie Koster
Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Bethesda, MD 20892, USA
Am J Epidemiol 167:1465-75. 2008..36). The finding that persons with a normal BMI but a large waist circumference had a higher mortality risk in this study suggests that increased waist circumference should be considered a risk factor for mortality, in addition to BMI...
Hemodynamics of increased pulse pressure in older women in the community-based Age, Gene/Environment Susceptibility-Reykjavik StudyGary F Mitchell
Cardiovascular Engineering Inc, 51 Sawyer Road, Suite 100, Waltham, MA 02453, USA
Hypertension 51:1123-8. 2008..4+/-1.4 mm Hg, P=0.75). Thus, reduced aortic diameter and impaired matching between diameter and flow accounts for the sex difference in pulse pressure in an unselected community-based cohort of older people...
Dietary glycemic index and glycemic load and the risk of type 2 diabetes in older adultsNadine R Sahyoun
Department of Nutrition and Food Science, University of Maryland, College Park, MD 20742, USA
Am J Clin Nutr 87:126-31. 2008..It is unclear whether immediate dietary effects on blood glucose influence the risk of developing type 2 diabetes...
Kidney dysfunction and fatal cardiovascular disease--an association independent of atherosclerotic events: results from the Health, Aging, and Body Composition (Health ABC) studyRajat Deo
Division of Cardiology, Johns Hopkins Hospital, Baltimore, MD, USA
Am Heart J 155:62-8. 2008..We evaluated whether impaired kidney function predicted risk of fatal cardiovascular disease independent of prevalent and incident cardiovascular events...
Diabetes-related complications, glycemic control, and falls in older adultsAnn V Schwartz
Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California 94107 1762, USA
Diabetes Care 31:391-6. 2008..We determined whether diabetes-related complications or treatments are associated with risk of falls in older diabetic adults...
Kidney function as a predictor of loss of lean mass in older adults: health, aging and body composition studyLinda F Fried
Renal Section, Veterans Affairs Pittsburgh Healthcare System Pittsburgh, Pennsylvania 15240, USA
J Am Geriatr Soc 55:1578-84. 2007..To assess the association between kidney function and change in body composition in older individuals...
Factors associated with impaired appetite in well-functioning community-dwelling older adultsJung Sun Lee
Department of Foods and Nutrition, University of Georgia, Athens, GA 30602, USA
J Nutr Elder 26:27-43. 2006..5 (1.6- 4.1)), poor self-reported health (2.4 (1.7-3.2)), current smoking, chewing problems, reported visual impairment, weight loss since age 50, and log (TNF-alpha) were significantly related to impaired appetite...
Psychosocial risk factors and the metabolic syndrome in elderly persons: findings from the Health, Aging and Body Composition studyNicole Vogelzangs
Department of Psychiatry and Institute for Research in Extramural Medicine, VU University Medical Center, Amsterdam, The Netherlands
J Gerontol A Biol Sci Med Sci 62:563-9. 2007..This study investigated the cross-sectional relationship between psychosocial risk factors and the metabolic syndrome in a community-based sample of older persons...
Inflammatory markers and incident fracture risk in older men and women: the Health Aging and Body Composition StudyJane A Cauley
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
J Bone Miner Res 22:1088-95. 2007..We tested this hypothesis in relationship to fractures in 2985 men and women enrolled in the Health ABC study. Results showed that subjects with the greatest number of inflammatory markers have the highest risk of fracture...
Reduced peripheral nerve function is related to lower hip BMD and calcaneal QUS in older white and black adults: the Health, Aging, and Body Composition StudyElsa S Strotmeyer
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
J Bone Miner Res 21:1803-10. 2006..Poor peripheral nerve function may directly affect bone...
Adipocytokines and incident diabetes mellitus in older adults: the independent effect of plasminogen activator inhibitor 1Alka M Kanaya
Division of General Internal Medicine, Department of Medicine, University of California, San Francisco, Suite 500, San Francisco, CA 94143 1732, USA
Arch Intern Med 166:350-6. 2006..Adipose tissue produces "adipocytokines" of uncertain clinical significance...
Aspirin use for the primary prevention of coronary heart disease in older adultsNicolas Rodondi
Department of Epidemiology and Biostatistics, University of California, San Francisco, Calif, USA
Am J Med 118:1288. 2005..We determined the prevalence of aspirin use in relation to coronary heart disease risk and changes over time...
Physical activity, exercise, and inflammatory markers in older adults: findings from the Health, Aging and Body Composition StudyLisa H Colbert
Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Bethesda, Maryland, USA
J Am Geriatr Soc 52:1098-104. 2004..To examine the association between physical activity and inflammatory markers, with consideration for body fatness and antioxidant use...
Diabetes is associated independently of body composition with BMD and bone volume in older white and black men and women: The Health, Aging, and Body Composition StudyElsa S Strotmeyer
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
J Bone Miner Res 19:1084-91. 2004..01) and higher hip BMD for each race-gender group (p < or = 0.01). Type 2 diabetes was associated with a 4-5% higher total hip BMD in all race-gender groups of elderly adults, independent of body composition and fasting insulin levels...
Cholesterol and health in old age: risk factor or risk marker?Tamara B Harris
J Am Geriatr Soc 52:639-40. 2004
Energy requirements in the eighth decade of lifeStephane Blanc
University of Wisconsin Madison, WI 53706, USA
Am J Clin Nutr 79:303-10. 2004..Knowledge of energy requirements among relatively healthy elderly is limited...
Edentulism and nutritional status in a biracial sample of well-functioning, community-dwelling elderly: the health, aging, and body composition studyJung Sun Lee
Division of Geriatric Medicine, University of Pittsburgh, PA 15213, USA
Am J Clin Nutr 79:295-302. 2004..Edentulism may affect dietary intake in older adults, but the relation between edentulism and nutritional status is not completely understood...
Alcohol intake and cerebral abnormalities on magnetic resonance imaging in a community-based population of middle-aged adults: the Atherosclerosis Risk in Communities (ARIC) studyJingzhong Ding
Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe St, Room 6009, Baltimore, MD 21205, USA
Stroke 35:16-21. 2004..We examined the associations of alcohol intake with MRI-defined cerebral abnormalities in a middle-aged, population-based cohort...
Diabetes is associated with subclinical functional limitation in nondisabled older individuals: the Health, Aging, and Body Composition studyNathalie de Rekeneire
Laboratory of Epidemiology, Demography and Biometry, National Institute on Aging, Bethesda, Maryland, USA
Diabetes Care 26:3257-63. 2003....
Neck and shoulder pain in 70- to 79-year-old men and women: findings from the Health, Aging and Body Composition StudyMolly T Vogt
Department of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, PA 15213, USA
Spine J 3:435-41. 2003..Musculoskeletal pain in the cervicobrachial region is considered a major health problem among adults of working age, but little is known about the impact of this pain in the elderly...
Racial differences in glycemic control in a well-functioning older diabetic population: findings from the Health, Aging and Body Composition StudyNathalie de Rekeneire
Laboratory of Epidemiology, Demography and Biometry, National Institute on Aging, National Institutes of Health, Bethesda, Maryland 20892 9205, USA
Diabetes Care 26:1986-92. 2003..We further hypothesized that the association of race with poorer glycemic control would be limited to those with lower education or lower income...
One- and two-year change in body composition as measured by DXA in a population-based cohort of older men and womenMarjolein Visser
Institute for Research in Extramural Medicine, Vrije University Medical Center, 1081 BT Amsterdam, The Netherlands
J Appl Physiol 94:2368-74. 2003..Loss of ALST was greater in men compared with women, and greater in blacks compared with whites, suggesting that men and blacks may be more prone to muscle loss...
Association between regional adipose tissue distribution and both type 2 diabetes and impaired glucose tolerance in elderly men and womenBret H Goodpaster
Department of Medicine, University of Pittsburgh Medical Center, Pennsylvania 15213, USA
Diabetes Care 26:372-9. 2003....
Change in muscle strength explains accelerated decline of physical function in older women with high interleukin-6 serum levelsLuigi Ferrucci
Laboratory of Clinical Epidemiology, INRCA Geriatric Department, Florence, Italy
J Am Geriatr Soc 50:1947-54. 2002..To test whether accelerated sarcopenia in older persons with high interleukin (IL)-6 serum levels plays a role in the prospective association between inflammation and disability found in many studies...
Leg muscle mass and composition in relation to lower extremity performance in men and women aged 70 to 79: the health, aging and body composition studyMarjolein Visser
Institute for Research in Extramural Medicine, Faculty of Medicine, Vrije Universiteit, Amsterdam, The Netherlands
J Am Geriatr Soc 50:897-904. 2002..Our aim was to determine whether low leg muscle mass and greater fat infiltration in the muscle were associated with poor lower extremity performance (LEP)...
Serum leptin concentrations and body adipose measures in older black and white adultsConstance E Ruhl
Social and Scientific Systems, Inc, 8758 Georgia Avenue, Silver Spring, MD 20910, USA
Am J Clin Nutr 80:576-83. 2004..Among US adults, serum leptin concentrations are higher in women than in men and are higher in blacks than in whites independent of anthropometric measures of body fatness...
Association between physical and cognitive function in healthy elderly: the health, aging and body composition studyCaterina Rosano
Department of Medicine, Division of Geriatric Medicine, University of Pittsburgh, Pittsburgh, PA 15260, USA
Neuroepidemiology 24:8-14. 2005..Longitudinal studies are needed to determine the direction of causality in this relationship...
Cystatin C and mortality risk in the elderly: the health, aging, and body composition studyMichael G Shlipak
University of San Francisco, General Internal Medicine Section, VA Medical Center (111A1, 4150 Clement Street, San Francisco, CA 94121, USA
J Am Soc Nephrol 17:254-61. 2006..39], 0.95 [0.68 to 1.32], 1.11 [0.79 to 1.57], 1.16 [0.86 to 1.58]). Cystatin C is a strong, independent risk factor for mortality in the elderly. Future studies should investigate whether cystatin C has a role in clinical medicine...
Lipoprotein peroxidation and mobility limitation: results from the Health, Aging, and Body Composition StudyMatteo Cesari
Department of Aging and Geriatric Research, College of Medicine, Institute on Aging, University of Florida, Gainesville 32608, USA
Arch Intern Med 165:2148-54. 2005..The aim of this study was to assess the predictive value of a lipoprotein peroxidation marker, oxidized low-density lipoprotein (oxLDL) for incident mobility limitation (ML)...
Weight change and the conservation of lean mass in old age: the Health, Aging and Body Composition StudyAnne B Newman
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15213, USA
Am J Clin Nutr 82:872-8; quiz 915-6. 2005..Weight loss may contribute to the loss of lean mass with age...
Dietary glycemic index and load, measures of glucose metabolism, and body fat distribution in older adultsNadine R Sahyoun
Department of Nutrition and Food Science, University of Maryland, College Park, MD 20742, USA
Am J Clin Nutr 82:547-52. 2005..Recent evidence suggests that the rate of carbohydrate digestion and absorption may influence the development of type 2 diabetes...
Is there a biomedical explanation for socioeconomic differences in incident mobility limitation?Annemarie Koster
Department of Health Care Studies, Section Medical Sociology, Universiteit Maastricht, Maastricht, The Netherlands
J Gerontol A Biol Sci Med Sci 60:1022-7. 2005..This study examines the association between socioeconomic status and incident mobility limitation in well-functioning older adults, and seeks to determine whether this link could be explained by biomedical factors...
Cross-sectional associations between trunk muscle composition, back pain, and physical function in the health, aging and body composition studyGregory E Hicks
Clinical Research Branch, National Institute on Aging, Baltimore, MD 21201, USA
J Gerontol A Biol Sci Med Sci 60:882-7. 2005..We hypothesized that lower trunk muscle area and attenuation (higher fat infiltration) are associated with decreased functional capacity...
Muscle mass, muscle strength, and muscle fat infiltration as predictors of incident mobility limitations in well-functioning older personsMarjolein Visser
Institute for Research in Extramural Medicine, VU University Medical Center, Van der Boechorststraat 7, 1081 BT Amsterdam, The Netherlands
J Gerontol A Biol Sci Med Sci 60:324-33. 2005..This study aims to investigate whether low muscle mass, low muscle strength, and greater fat infiltration into the muscle predict incident mobility limitation...
Obesity, regional body fat distribution, and the metabolic syndrome in older men and womenBret H Goodpaster
Department of Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
Arch Intern Med 165:777-83. 2005..We determined whether patterns of regional fat deposition are associated with metabolic syndrome in older adults...
Adipose tissue in muscle: a novel depot similar in size to visceral adipose tissueDympna Gallagher
Department of Medicine, Obesity Research Center, St Luke's-Roosevelt Hospital, New York, NY, USA
Am J Clin Nutr 81:903-10. 2005..CONCLUSION: Race differences in AT distribution extend to IMAT, a depot that may influence race-ethnicity differences in dysglycemia...
Diabetes and bone loss at the hip in older black and white adultsAnn V Schwartz
Department of Epidemiology and Biostatistics, University of California, San Francisco, California 94105, USA
J Bone Miner Res 20:596-603. 2005....
Population structure, admixture, and aging-related phenotypes in African American adults: the Cardiovascular Health StudyAlexander P Reiner
Department of Epidemiology, University of Washington, Seattle, WA 98101 1448, USA
Am J Hum Genet 76:463-77. 2005..Complementary methods that identify discrete subgroups on the basis of genetic similarity may help to further characterize the complex biodemographic structure of human populations...
The association of regional fat depots with hypertension in older persons of white and African American ethnicityJingzhong Ding
Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, USA
Am J Hypertens 17:971-6. 2004..Fat distribution has been shown to be a strong correlate of hypertension, independent of general obesity. However, population-based studies are lacking on the association of regional fat depots with hypertension...
Association of visceral adipose tissue with incident myocardial infarction in older men and women: the Health, Aging and Body Composition StudyBarbara J Nicklas
Section on Gerontology and Geriatric Medicine, Sticht Center on Aging, Wake Forest University School of Medicine, Winston Salem, NC, USA
Am J Epidemiol 160:741-9. 2004..79, 95% confidence interval: 1.24, 2.58 per standard-deviation increase; p < 0.01). The amount of adipose tissue stored in the intraabdominal cavity is an important, independent risk factor for MI in well-functioning, elderly women...
Peripheral blood markers of inflammation predict mortality and functional decline in high-functioning community-dwelling older personsDavid B Reuben
Multicampus Program in Geriatric Medicine and Gerontology, UCLA School of Medicine, Los Angeles, California 90095, USA
J Am Geriatr Soc 50:638-44. 2002..The objective of this study was to determine the prognostic value of combining four peripheral blood measures of inflammation in healthy older persons...
