Research Topics
Species | Linda C HarlanSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
Trends in the treatment and survival for local and regional cutaneous melanoma in a US population-based studyLinda C Harlan
Applied Research Program, National Cancer Institute, Bethesda, MD, USA
Melanoma Res 21:547-54. 2011..Survival was associated with tumor thickness. Early detection when the tumor thickness is less may decrease mortality. Future research should especially target decreasing the disparity in survival between men and women...
Factors associated with initial therapy for clinically localized prostate cancer: prostate cancer outcomes studyL C Harlan
Applied Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
J Natl Cancer Inst 93:1864-71. 2001..We examined the association of sociodemographic and clinical characteristics with four management options: radical prostatectomy, radiation therapy, hormonal therapy, and watchful waiting...- Insurance status and the use of guideline therapy in the treatment of selected cancersLinda C Harlan
Division of Cancer Control and Population Sciences, Cancer Therapy Evaluation Program, National Cancer Institute, National Institute of Health, Bethesda, MD 20892 7344, USA
J Clin Oncol 23:9079-88. 2005..This study estimates the impact of type of insurance coverage on the receipt of guideline therapy in a population-based sample of cancer patients treated in the community... - Comorbidities, therapy, and newly diagnosed conditions for women with early stage breast cancerLinda C Harlan
Applied Research Program, National Cancer Institute, 6130 Executive Blvd, MSC 7344, Bethesda, MD 20892, USA
J Cancer Surviv 3:89-98. 2009..To describe comorbidities in breast cancer patients at diagnosis and examine factors associated with self-reported comorbidities 30 months post-diagnosis... - Trends in surgery and chemotherapy for women diagnosed with ovarian cancer in the United StatesLinda C Harlan
National Cancer Institute, 6130 Executive Blvd, MSC 7344, Bethesda, MD 20892 7344, USA
J Clin Oncol 21:3488-94. 2003..We examined patterns of care in a population-based sample of 601 ovarian cancer patients diagnosed in 1991, and a sample of 566 women was selected in 1996 to examine trends in care... - Breast cancer in men in the United States: a population-based study of diagnosis, treatment, and survivalLinda C Harlan
Applied Research Program, National Cancer Institute, Bethesda, Maryland 20892 7344, USA
Cancer 116:3558-68. 2010..Recommendations suggest treating men who are diagnosed with breast cancer using the guidelines for postmenopausal women; however, to date, no population-based studies have evaluated patterns of care... - Adjuvant therapy for breast cancer: practice patterns of community physiciansLinda C Harlan
Applied Research Program, National Cancer Institute, Bethesda, MD 20892, USA
J Clin Oncol 20:1809-17. 2002..We evaluated the use of adjuvant therapy for breast cancer using the National Institutes of Health (NIH) Consensus Development Conference statements as guideposts for assessing how rapidly community physicians adopt recommended therapies... - Community-based use of chemotherapy and hormonal therapy for early-stage breast cancer: 1987-2000Linda C Harlan
Applied Research Program, National Cancer Institute, Bethesda, MD 20892 7344, USA
J Clin Oncol 24:872-7. 2006..We describe trends in the use of chemotherapy and hormonal therapy by nodal and estrogen receptor (ER) status in women with early-stage breast cancer... - Recruitment and follow-up of adolescent and young adult cancer survivors: the AYA HOPE StudyLinda C Harlan
National Cancer Institute, 6130 Executive Blvd, MSC 7344, Bethesda, MD 20892 7344, USA
J Cancer Surviv 5:305-14. 2011..Furthermore, participation in research by AYAs is typically low. We conducted a study to examine the feasibility of recruiting a population-based sample of AYA survivors to examine issues of treatment and health outcomes... 
Population-based estimate of the prevalence of HER-2 positive breast cancer tumors for early stage patients in the USKathleen A Cronin
Surveillance Research Program, National Cancer Institute, Bethesda, Maryland, USA
Cancer Invest 28:963-8. 2010..Tumor grade and race were associated with HER-2 for women aged ≥ 50 years after controlling for other variables. HER-2 varies by age and by race and tumor in older women...- Cancer, comorbidities, and health-related quality of life of older adultsAshley Wilder Smith
National Cancer Institute NCI, Bethesda, MD 20892 7344, USA
Health Care Financ Rev 29:41-56. 2008..Negative associations were most pronounced in those with two or more comorbidities and in those diagnosed with cancer within the past year... - Pre-operative imaging, surgery and adjuvant therapy for women diagnosed with cancer of the corpus uteri in community practice in the United StatesEdward L Trimble
National Cancer Institute, Surgery Section, 6130 Executive Boulevard, Ste 741, M, Bethesda, MD 20892 7436, USA
Gynecol Oncol 96:741-8. 2005..Non-Hispanic black women are less often diagnosed with endometrial cancer than are non-Hispanic white women, but are more likely to die of their disease. Reasons for this disparity in outcome are not well understood... - Do patients consistently report comorbid conditions over time?: results from the prostate cancer outcomes studyCarrie N Klabunde
Health Services and Economics Branch, Applied Research Program, Surveillance Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, Maryland 20892 7344, USA
Med Care 43:391-400. 2005..Comorbidity is an important dimension of patient health status. However, limited attention has been given to assessing the reliability of patient-reported data on comorbid conditions... - Racial/ethnic variation in clinical presentation, treatment, and survival among breast cancer patients under age 35Vickie L Shavers
Applied Research Program, Health Service and Economics Branch, Division of Cancer Control and Population Science, National Cancer Institute, 6130 Executive Boulevard, MSC 7344, EPN Room 4005, Bethesda, MD 20892 7344, USA
Cancer 97:134-47. 2003.... - Patterns of care for adjuvant therapy in a random population-based sample of patients diagnosed with colorectal cancerDeirdre P Cronin
Surveillance Research Program, DCCPS, National Cancer Institute, Bethesda, Maryland, USA
Am J Gastroenterol 101:2308-18. 2006..Age disparities remain despite no evidence of greater chemotherapy-induced toxicity in the elderly. More equitable receipt of cancer treatment to all segments of the community will help to reduce mortality... - Data sources for measuring comorbidity: a comparison of hospital records and medicare claims for cancer patientsCarrie N Klabunde
Health Services and Economics Branch, Applied Research Program, National Cancer Institute, Bethesda, MD 20892 7344, USA
Med Care 44:921-8. 2006..Identifying appropriate comorbidity data sources is a key consideration in health services and outcomes research... - Utility of the SEER-Medicare data to identify chemotherapy useJoan L Warren
Applied Research Program, National Cancer Institute, Bethesda, Maryland 20892 7344
Med Care 40:IV-55-61. 2002..However, the validity and completeness of these data as a source of information has not been established... - Trends in use of adjuvant multi-agent chemotherapy and tamoxifen for breast cancer in the United States: 1975-1999Angela Mariotto
Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 8317, USA
J Natl Cancer Inst 94:1626-34. 2002..We evaluated trends in the use of adjuvant multi-agent chemotherapy, tamoxifen, and the combination of both treatments for early-stage breast cancer in the United States from 1975 through 1999... - A population-based study of therapy and survival for patients with head and neck cancer treated in the communityClaudio Dansky Ullmann
Cancer Therapy Evaluation Program, National Cancer Institute, Bethesda, MD, USA
Cancer 118:4452-61. 2012..The objective of this study was to examine patterns of care and survival in a population-based sample of patients with head and neck cancer (HNC) who were treated in the community or in hospitals that had residency training programs... - Clinical trial participation and time to treatment among adolescents and young adults with cancer: does age at diagnosis or insurance make a difference?Helen M Parsons
Applied Research Program, National Cancer Institute, Bethesda, MD 20892 7344, USA
J Clin Oncol 29:4045-53. 2011..To identify current trends in AYA care, we examined patterns of clinical trial participation, time to treatment, and provider characteristics in a population-based sample of AYA patients with cancer... - Racial/ethnic patterns of care for cancers of the oral cavity, pharynx, larynx, sinuses, and salivary glandsVickie L Shavers
National Cancer Institute, Division of Cancer Control and Population Science, Applied Research Program, Health Services and Economic Branch, Bethesda, MD 20892 7344, USA
Cancer Metastasis Rev 22:25-38. 2003..We examine racial/ethnic variation in tumor characteristics, treatment practices, and their relationship to survival for cancers of the oral cavity, pharynx, larynx, nasal cavity and salivary glands... - Is mode of breast cancer detection associated with cancer treatment in the United States?K Robin Yabroff
Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD 20892 7344, USA
Cancer 112:1011-9. 2008..In the current study, the authors explored whether detection by mammography was associated with greater use of guideline-consistent breast cancer treatment among patients with recently diagnosed breast cancer in the United States... - Five-year outcomes after prostatectomy or radiotherapy for prostate cancer: the prostate cancer outcomes studyArnold L Potosky
Division of Cancer Control and Population Sciences, National Cancer Institute, EPN Rm 4005, 6130 Executive Blvd, MSC 7344, Bethesda, MD 20892 7344, USA
J Natl Cancer Inst 96:1358-67. 2004..We present treatment-specific quality-of-life outcomes for prostate cancer patients 5 years after initial diagnosis... - Ductal carcinoma in situ: trends in treatment over time in the USJo Anne Zujewski
National Cancer Institute, CTEP, Bethesda, MD, USA
Breast Cancer Res Treat 127:251-7. 2011..Despite positive HER-2 tests no women received trastuzumab as of 2005. Despite the lack of clinical trials evidence, aromatase inhibitors are being prescribed for women with DCIS... - The frequency of ipsilateral second tumors after breast-conserving surgery for DCIS: a population based analysisJoan L Warren
Health Services and Economics Branch Applied Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, Maryland 20892 7344, USA
Cancer 104:1840-8. 2005..This analysis of women treated with breast-conserving surgery (BCS) evaluated the impact of radiation therapy (RT) in patient outcomes... - Patterns of care for women with cervical cancer in the United StatesEdward L Trimble
National Cancer Institute, Surgery Section, Bethesda, Maryland 20892 7436, USA
Cancer 113:743-9. 2008..This analysis was initiated to determine any systemic changes in management of cervical cancers... - Untreated cervical cancer in the United StatesEdward L Trimble
Surgery Section, National Cancer Institute, 6130 Executive Boulevard, Suite 741, MSC 7436, Bethesda, MD 20892 7436, USA
Gynecol Oncol 96:271-7. 2005..To evaluate treatment patterns, including lack of treatment, among women diagnosed with cervical cancer in the United States... - Feasibility study for collection of HER2 data by National Cancer Institute (NCI) Surveillance, Epidemiology, and End Results (SEER) Program central cancer registriesMarsha E Reichman
Division of Cancer Control and Population Sciences, National Cancer Institute, 6130 Executive Boulevard, Suite 6138, Rockville, MD 20852, USA
Cancer Epidemiol Biomarkers Prev 19:144-7. 2010.... - Racial/ethnic patterns of care for pancreatic cancerVickie L Shavers
Applied Research Program, National Cancer Institute, Bethesda, Maryland 20892, USA
J Palliat Med 12:623-30. 2009..Racial/ethnic cancer treatment disparities have been observed for many cancer sites. We examine patterns of care in a population-based sample of African American, Hispanic and non-Hispanic white patients diagnosed with pancreatic cancer... - Age, sex, and racial differences in the use of standard adjuvant therapy for colorectal cancerArnold L Potosky
Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
J Clin Oncol 20:1192-202. 2002..Trends, patterns, and outcomes of adjuvant therapy for colorectal cancer, focusing on age, sex, and racial/ethnic differences, are reported... - Identifying specific chemotherapeutic agents in medicare data: a validation studyJennifer L Lund
Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC Health Services and Economics Branch, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD Division of Hematology and Oncology, School of Medicine, University of Virginia, Charlottesville, VA Division of Gastroenterology and Hepatology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC
Med Care 51:e27-34. 2013..Misclassification of chemotherapy could bias estimates of frequency and association, warranting an updated assessment...