A C Hansson

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi Time-course of immediate early gene expression in hippocampal subregions of adrenalectomized rats after acute corticosterone challenge
    Anita C Hansson
    Department of Neuroscience, Karolinska Institutet, 10401 Stockholm, Sweden
    Brain Res 1215:1-10. 2008
  2. ncbi Corticosterone actions on the hippocampal brain-derived neurotrophic factor expression are mediated by exon IV promoter
    A C Hansson
    Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden
    J Neuroendocrinol 18:104-14. 2006
  3. ncbi Neuroplasticity in brain reward circuitry following a history of ethanol dependence
    Anita C Hansson
    Laboratory of Clinical and Translational Studies, NIAAA NIH, Bethesda, MD 20892 1108, USA
    Eur J Neurosci 27:1912-22. 2008
  4. ncbi Induction of hippocampal glial cells expressing basic fibroblast growth factor RNA by corticosterone
    A C Hansson
    Department of Neuroscience, Karolinska Institute, Stockholm, Sweden
    Neuroreport 12:141-5. 2001
  5. ncbi c-fos reduces corticosterone-mediated effects on neurotrophic factor expression in the rat hippocampal CA1 region
    A C Hansson
    Department of Neuroscience, Karolinska Institutet, 171 77 Stockholm, Sweden
    J Neurosci 23:6013-22. 2003
  6. ncbi Modulation of voluntary ethanol consumption by beta-arrestin 2
    K Bjork
    Laboratory of Clinical and Translational Studies, NIAAA NIH, 10 Center Dr, Bethesda, MD 20892 1108, USA
    FASEB J 22:2552-60. 2008
  7. ncbi Biphasic autoregulation of mineralocorticoid receptor mRNA in the medial septal nucleus by aldosterone
    Anita C Hansson
    Department of Neuroscience, Karolinska Institute, Stockholm, Sweden
    Neuroendocrinology 75:358-66. 2002
  8. ncbi Variation at the rat Crhr1 locus and sensitivity to relapse into alcohol seeking induced by environmental stress
    A C Hansson
    Laboratory of Clinical and Translational Studies, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 103:15236-41. 2006
  9. ncbi Translating the neuroscience of alcoholism into clinical treatments: from blocking the buzz to curing the blues
    Markus Heilig
    Laboratory of Clinical and Translational Studies, National Inst on Alcohol Abuse and Alcoholism, National Inst of Health, Bethesda, MD, United States
    Neurosci Biobehav Rev 35:334-44. 2010
  10. ncbi Comparative localization of fibroblast growth factor receptor-1, -2, and -3 mRNAs in the rat brain: in situ hybridization analysis
    N Belluardo
    Department of Neuroscience, Karolinska Institute, Stockholm, Sweden
    J Comp Neurol 379:226-46. 1997

Collaborators

Detail Information

Publications23

  1. ncbi Time-course of immediate early gene expression in hippocampal subregions of adrenalectomized rats after acute corticosterone challenge
    Anita C Hansson
    Department of Neuroscience, Karolinska Institutet, 10401 Stockholm, Sweden
    Brain Res 1215:1-10. 2008
    ..8 h. The early reduction in c-fos family and junB transcripts may contribute to the GR/MR-dependent changes on hippocampal plasticity and may be dependent on rapid corticosteroid signaling...
  2. ncbi Corticosterone actions on the hippocampal brain-derived neurotrophic factor expression are mediated by exon IV promoter
    A C Hansson
    Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden
    J Neuroendocrinol 18:104-14. 2006
    ..The results could be confirmed with real-time PCR in the dentate gyrus. It appears as if the exon IV promoter is the major target for corticosterone-mediated transcriptional regulation of BDNF in the hippocampus...
  3. ncbi Neuroplasticity in brain reward circuitry following a history of ethanol dependence
    Anita C Hansson
    Laboratory of Clinical and Translational Studies, NIAAA NIH, Bethesda, MD 20892 1108, USA
    Eur J Neurosci 27:1912-22. 2008
    ..These two neuroadaptations could act in concert to facilitate progression into ethanol dependence...
  4. ncbi Induction of hippocampal glial cells expressing basic fibroblast growth factor RNA by corticosterone
    A C Hansson
    Department of Neuroscience, Karolinska Institute, Stockholm, Sweden
    Neuroreport 12:141-5. 2001
    ..These data suggest that in a subpopulation of hippocampal glial cells corticosterone regulates bFGF gene expression transcriptionally in an on/off manner...
  5. ncbi c-fos reduces corticosterone-mediated effects on neurotrophic factor expression in the rat hippocampal CA1 region
    A C Hansson
    Department of Neuroscience, Karolinska Institutet, 171 77 Stockholm, Sweden
    J Neurosci 23:6013-22. 2003
    ..There were no effects of c-fos antisense on hippocampal GR and MR expression. Thus it seems that a tonic c-fos mechanism exists within CA1, which reduces GR- and MR-mediated effects on expression of bFGF and BDNF...
  6. ncbi Modulation of voluntary ethanol consumption by beta-arrestin 2
    K Bjork
    Laboratory of Clinical and Translational Studies, NIAAA NIH, 10 Center Dr, Bethesda, MD 20892 1108, USA
    FASEB J 22:2552-60. 2008
    ..Our results demonstrate that beta-arrestin 2 modulates acute responses to ethanol and is an important mediator of ethanol reward...
  7. ncbi Biphasic autoregulation of mineralocorticoid receptor mRNA in the medial septal nucleus by aldosterone
    Anita C Hansson
    Department of Neuroscience, Karolinska Institute, Stockholm, Sweden
    Neuroendocrinology 75:358-66. 2002
    ..Activated MR in the medial septal nucleus may therefore take part in the regulation of septo-hippocampal cholinergic pathways and thus of limbic circuits...
  8. ncbi Variation at the rat Crhr1 locus and sensitivity to relapse into alcohol seeking induced by environmental stress
    A C Hansson
    Laboratory of Clinical and Translational Studies, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 103:15236-41. 2006
    ..These data demonstrate that Crhr1 genotype and expression interact with environmental stress to reinstate alcohol-seeking behavior...
  9. ncbi Translating the neuroscience of alcoholism into clinical treatments: from blocking the buzz to curing the blues
    Markus Heilig
    Laboratory of Clinical and Translational Studies, National Inst on Alcohol Abuse and Alcoholism, National Inst of Health, Bethesda, MD, United States
    Neurosci Biobehav Rev 35:334-44. 2010
    ....
  10. ncbi Comparative localization of fibroblast growth factor receptor-1, -2, and -3 mRNAs in the rat brain: in situ hybridization analysis
    N Belluardo
    Department of Neuroscience, Karolinska Institute, Stockholm, Sweden
    J Comp Neurol 379:226-46. 1997
    ..Their apparent cellular specificity suggests that these receptor subtypes can have a differential trophic role in the brain, reflecting the various biological activities shown by the ligands of the FGF family...
  11. ncbi NF-kappaB mediated glucocorticoid response in the inner ear after acoustic trauma
    Yeasmin Tahera
    Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden
    J Neurosci Res 83:1066-76. 2006
    ....
  12. ncbi Upregulation of voluntary alcohol intake, behavioral sensitivity to stress, and amygdala crhr1 expression following a history of dependence
    Wolfgang H Sommer
    Laboratory of Clinical and Translational Studies, National Institute on Alcohol Abuse and Alcoholism National Institutes of Health, Bethesda, Maryland 20892 1108, USA
    Biol Psychiatry 63:139-45. 2008
    ..A history of alcohol dependence recruits increased voluntary alcohol intake and sensitivity to stress. Corticotropin-releasing hormone (CRH) has been implicated in this transition, but underlying molecular mechanisms remain unclear...
  13. ncbi Genetic impairment of frontocortical endocannabinoid degradation and high alcohol preference
    Anita C Hansson
    Laboratory of Clinical and Translational Studies, NIAAA, National Institutes of Health, Bethesda, MD 20892 1108, USA
    Neuropsychopharmacology 32:117-26. 2007
    ..These results show for the first time that impaired FAAH function may confer a phenotype of high voluntary alcohol intake, and point to a FAAH both as a potential susceptibility factor and a therapeutic target...
  14. ncbi Glucocorticoid receptor and nuclear factor-kappa B interactions in restraint stress-mediated protection against acoustic trauma
    Yeasmin Tahera
    Department of Physiology and Pharmacology, Karolinska Institutet, 171 77 Stockholm, Sweden
    Endocrinology 147:4430-7. 2006
    ..These results emphasis how GR activity modulates hearing sensitivity and its importance for the rationale use of glucocorticoids in inner ear diseases...
  15. ncbi Neuropeptide Y (NPY) suppresses yohimbine-induced reinstatement of alcohol seeking
    Andrea Cippitelli
    Laboratory of Clinical and Translational Studies, National Institute of Alcohol Abuse and Alcoholism NIAAA, National Institutes of Health NIH, 10 Center Dr 1 5330, Bethesda, MD 20892 1108, USA
    Psychopharmacology (Berl) 208:417-26. 2010
    ..Here, we examined whether neuropeptide Y (NPY), an endogenous anti-stress mediator, blocks reinstatement of alcohol-seeking induced by the pharmacological stressor yohimbine...
  16. ncbi Acute ethanol challenge inhibits glycogen synthase kinase-3beta in the rat prefrontal cortex
    Olga Neznanova
    Laboratory of Clinical and Translational Studies, NIAAA, National Institutes of Health, Bethesda, MD, USA
    Int J Neuropsychopharmacol 12:275-80. 2009
    ..Together, these results identify candidate pathways for mediating high ethanol preference and emphasize the importance of the mPFC in controlling this behaviour...
  17. ncbi Genetic variation and brain gene expression in rodent models of alcoholism implications for medication development
    Karl Björk
    Translational Neuropharmacology, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden
    Int Rev Neurobiol 91:129-71. 2010
    ..Examples of a convergent research approach include validation studies for Agt, Arrb2, Crhr1, Grin3a, and Npy...
  18. ncbi Region-specific down-regulation of Crhr1 gene expression in alcohol-preferring msP rats following ad lib access to alcohol
    Anita C Hansson
    Laboratory of Clinical and Translational Studies, NIAAA NIH, Bethesda, MD 20892 1108, USA
    Addict Biol 12:30-4. 2007
    ....
  19. ncbi Dynamic reorganization of striatal circuits during the acquisition and consolidation of a skill
    Henry H Yin
    Laboratory for Integrative Neuroscience, National Institute on Alcohol Abuse and Alcoholism, US National Institutes of Health, 5625 Fishers Lane, MSC 9411, Bethesda, Maryland 20852 9411, USA
    Nat Neurosci 12:333-41. 2009
    ..These findings demonstrate that region- and pathway-specific plasticity sculpts the circuits involved in the performance of the skill as it becomes automatized...
  20. ncbi Dysregulation of nociceptin/orphanin FQ activity in the amygdala is linked to excessive alcohol drinking in the rat
    Daina Economidou
    Department of Experimental Medicine and Public Health, University of Camerino, Camerino MC, Italy
    Biol Psychiatry 64:211-8. 2008
    ....
  21. ncbi Cannabinoid CB1 receptor antagonism reduces conditioned reinstatement of ethanol-seeking behavior in rats
    Andrea Cippitelli
    , Avenida Carlos Haya 82, 7 Planta, , 29010 Malaga, Spain
    Eur J Neurosci 21:2243-51. 2005
    ..In addition, current pharmacological and neuroanatomical data suggest that an altered function of the CB1 receptor system exists between genetically selected alcohol-preferring msP rats and a heterogeneous animal population...
  22. ncbi Corticosterone strongly increases the affinity of dorsal raphe 5-HT1A receptors
    Inmaculada Bellido
    Department of Pharmacology and Clinical Therapeutics, School of Medicine, University of Malaga, MA 29071, Malaga, Spain
    Neuroreport 15:1457-9. 2004
    ..Glucocorticoids, by enhancing dorsal raphe 5-HT1A autoreceptor function, may therefore cause reduced 5-HT neuronal activity and thus lead to a depressive state...
  23. ncbi c-fos antisense oligonucleotides increase firing rate of striatal neurons in the anaesthetized rat
    Ingrid Stromberg
    Department of Integrative Medical Biology, Umea University, Umea, Sweden
    Brain Res 1000:192-4. 2004
    ..We conclude that, under urethane anesthesia, which here does not affect c-fos expression in the striatum by itself, neuronal activity appears to be tonically suppressed by basal striatal c-fos expression...