Lianyi Han

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc The Text-mining based PubChem Bioassay neighboring analysis
    Lianyi Han
    National Center for Biotechnology Information, US National Library of Medicine, 8600 Rockville Pike, Bethesda, MD 20894, USA
    BMC Bioinformatics 11:549. 2010
  2. pmc Developing and validating predictive decision tree models from mining chemical structural fingerprints and high-throughput screening data in PubChem
    Lianyi Han
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA
    BMC Bioinformatics 9:401. 2008
  3. pmc PubChem's BioAssay Database
    Yanli Wang
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA
    Nucleic Acids Res 40:D400-12. 2012
  4. pmc PubChem3D: a new resource for scientists
    Evan E Bolton
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Department of Health and Human Services, 8600 Rockville Pike, Bethesda, MD 20894, USA
    J Cheminform 3:32. 2011
  5. pmc The NCBI BioSystems database
    Lewis Y Geer
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bldg 38A, 8600 Rockville Pike, Bethesda, MD 20894, USA
    Nucleic Acids Res 38:D492-6. 2010
  6. pmc A survey of across-target bioactivity results of small molecules in PubChem
    Lianyi Han
    National Center for Biotechnology Information, National Institutes of Health, Bethesda, MD 20894, USA
    Bioinformatics 25:2251-5. 2009

Detail Information

Publications6

  1. pmc The Text-mining based PubChem Bioassay neighboring analysis
    Lianyi Han
    National Center for Biotechnology Information, US National Library of Medicine, 8600 Rockville Pike, Bethesda, MD 20894, USA
    BMC Bioinformatics 11:549. 2010
    ..In this work, we propose a text-mining based approach for bioassay neighboring analysis from the unstructured text descriptions contained in the PubChem BioAssay database...
  2. pmc Developing and validating predictive decision tree models from mining chemical structural fingerprints and high-throughput screening data in PubChem
    Lianyi Han
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA
    BMC Bioinformatics 9:401. 2008
    ..Computational approaches for the analysis of HTS results face great challenges due to the large quantity of information and significant amounts of erroneous data produced...
  3. pmc PubChem's BioAssay Database
    Yanli Wang
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA
    Nucleic Acids Res 40:D400-12. 2012
    ..In this work, we provide an update for the PubChem BioAssay resource, including information content growth, data model extension and new developments of data submission, retrieval, analysis and download tools...
  4. pmc PubChem3D: a new resource for scientists
    Evan E Bolton
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Department of Health and Human Services, 8600 Rockville Pike, Bethesda, MD 20894, USA
    J Cheminform 3:32. 2011
    ..abstract:..
  5. pmc The NCBI BioSystems database
    Lewis Y Geer
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bldg 38A, 8600 Rockville Pike, Bethesda, MD 20894, USA
    Nucleic Acids Res 38:D492-6. 2010
    ....
  6. pmc A survey of across-target bioactivity results of small molecules in PubChem
    Lianyi Han
    National Center for Biotechnology Information, National Institutes of Health, Bethesda, MD 20894, USA
    Bioinformatics 25:2251-5. 2009
    ..This work enables one to select target specific inhibitors, identify promiscuous compounds and better understand the biological mechanisms of target-small molecule interactions...