Gerald R V Hammond

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc PI4P and PI(4,5)P2 are essential but independent lipid determinants of membrane identity
    Gerald R V Hammond
    Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1PD, UK
    Science 337:727-30. 2012
  2. doi request reprint Membrane biology: Making light work of lipids
    Gerald R V Hammond
    Section on Molecular Signal Transduction, Program for Developmental Neuroscience, the Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA
    Curr Biol 22:R869-71. 2012
  3. pmc A novel probe for phosphatidylinositol 4-phosphate reveals multiple pools beyond the Golgi
    Gerald R V Hammond
    Program in Developmental Neuroscience and 2 Cell Biology and Metabolism Program, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892
    J Cell Biol 205:113-26. 2014
  4. pmc Reversible binding and rapid diffusion of proteins in complex with inositol lipids serves to coordinate free movement with spatial information
    Gerald R V Hammond
    Department of Pharmacology, University of Cambridge, Cambridge, England, UK
    J Cell Biol 184:297-308. 2009
  5. pmc Immunocytochemical techniques reveal multiple, distinct cellular pools of PtdIns4P and PtdIns(4,5)P(2)
    Gerald R V Hammond
    Department of Pharmacology, University of Cambridge, Cambridge, UK
    Biochem J 422:23-35. 2009
  6. pmc Adenylyl cyclase AC8 directly controls its micro-environment by recruiting the actin cytoskeleton in a cholesterol-rich milieu
    Laura J Ayling
    Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1PD, UK
    J Cell Sci 125:869-86. 2012

Collaborators

Detail Information

Publications6

  1. pmc PI4P and PI(4,5)P2 are essential but independent lipid determinants of membrane identity
    Gerald R V Hammond
    Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1PD, UK
    Science 337:727-30. 2012
    ....
  2. doi request reprint Membrane biology: Making light work of lipids
    Gerald R V Hammond
    Section on Molecular Signal Transduction, Program for Developmental Neuroscience, the Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA
    Curr Biol 22:R869-71. 2012
    ..A clever genetic trick allows the lipid composition of the plasma membrane to be manipulated using light, paving the way for new investigations into the many membrane interactions that dictate cell shape, movement and communication...
  3. pmc A novel probe for phosphatidylinositol 4-phosphate reveals multiple pools beyond the Golgi
    Gerald R V Hammond
    Program in Developmental Neuroscience and 2 Cell Biology and Metabolism Program, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892
    J Cell Biol 205:113-26. 2014
    ..Therefore, P4M reports a wider cellular distribution of PtdIns4P than previous probes and therefore will be valuable for dissecting the biological functions of PtdIns4P in its assorted membrane compartments. ..
  4. pmc Reversible binding and rapid diffusion of proteins in complex with inositol lipids serves to coordinate free movement with spatial information
    Gerald R V Hammond
    Department of Pharmacology, University of Cambridge, Cambridge, England, UK
    J Cell Biol 184:297-308. 2009
    ..Moreover, our data reveal that GAP1(IP4BP), a protein that binds PtdIns(4,5)P(2) and PtdIns(3,4,5)P(3) in vitro with similar affinity, is able to "read" PtdIns(3,4,5)P(3) signals in terms of an elongated residence time at the membrane...
  5. pmc Immunocytochemical techniques reveal multiple, distinct cellular pools of PtdIns4P and PtdIns(4,5)P(2)
    Gerald R V Hammond
    Department of Pharmacology, University of Cambridge, Cambridge, UK
    Biochem J 422:23-35. 2009
    ..In addition, we present evidence that the majority of PtdIns4P resides in the plasma membrane, where it is metabolically distinct from the steady-state plasma membrane pool of PtdIns(4,5)P(2)...
  6. pmc Adenylyl cyclase AC8 directly controls its micro-environment by recruiting the actin cytoskeleton in a cholesterol-rich milieu
    Laura J Ayling
    Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1PD, UK
    J Cell Sci 125:869-86. 2012
    ....