Research Topics
Genomes and GenesSpecies | Jason A HallSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
The role of retinoic acid in tolerance and immunityJason A Hall
Mucosal Immunology Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
Immunity 35:13-22. 2011....
Commensal DNA limits regulatory T cell conversion and is a natural adjuvant of intestinal immune responsesJason A Hall
Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
Immunity 29:637-49. 2008..Together, these data point to gfDNA as a natural adjuvant for priming intestinal responses via modulation of Treg/Teff cell equilibrium...
Decrease of Foxp3+ Treg cell number and acquisition of effector cell phenotype during lethal infectionGuillaume Oldenhove
Mucosal Immunology Unit, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
Immunity 31:772-86. 2009..These data reveal a mechanism for Th1 cell pathogenicity that extends beyond their proinflammatory program to limit Treg cell survival...
Essential role for retinoic acid in the promotion of CD4(+) T cell effector responses via retinoic acid receptor alphaJason A Hall
Mucosal Immunology Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
Immunity 34:435-47. 2011....
GATA3 controls Foxp3⁺ regulatory T cell fate during inflammation in miceElizabeth A Wohlfert
Mucosal Immunology Unit, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, Maryland, USA
J Clin Invest 121:4503-15. 2011..Overall, our work reveals what we believe to be a new facet in the complex role of GATA3 in T cells and highlights what may be a fundamental role in controlling Treg physiology during inflammation...
Compartmentalized control of skin immunity by resident commensalsShruti Naik
Mucosal Immunology Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA
Science 337:1115-9. 2012..These findings underscore the importance of the microbiota as a distinctive feature of tissue compartmentalization, and provide insight into mechanisms of immune system regulation by resident commensal niches in health and disease...
Microbe-dendritic cell dialog controls regulatory T-cell fateJohn R Grainger
Mucosal Immunology Unit, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20894, USA
Immunol Rev 234:305-16. 2010..In this review, we discuss some new findings associating dendritic cells from defined compartments with the induction and control of regulatory T cells in the context of exposure to both commensal and pathogenic microbes...
Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acidCheng Ming Sun
Mucosal Immunology Unit, Laboratory of Parasitic Diseases, National Institute for Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
J Exp Med 204:1775-85. 2007..Together, these data demonstrate that the intestinal immune system has evolved a self-contained strategy to promote T reg cell neoconversion...
