Damien Hall

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint On the role of the macromolecular phase transitions in biology in response to change in solution volume or macromolecular composition: action as an entropy buffer
    Damien Hall
    Section on Physical Biochemistry, Laboratory of Biochemical Pharmacology, National Institute of Diabetes, Digestive and Kidney Diseases, National Institute of Health, Bethesda, MD 20892, USA
    Biophys Chem 98:233-48. 2002
  2. ncbi request reprint Use of optical biosensors for the study of mechanistically concerted surface adsorption processes
    D Hall
    Section on Physical Biochemistry, National Institute of Diabetes, Digestive, and Kidney Disease, Bethesda, Maryland, 20892, USA
    Anal Biochem 288:109-25. 2001
  3. ncbi request reprint Effects of inert volume-excluding macromolecules on protein fiber formation. II. Kinetic models for nucleated fiber growth
    Damien Hall
    Section on Physical Biochemistry, Laboratory of Biochemistry and Genetics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA
    Biophys Chem 107:299-316. 2004
  4. ncbi request reprint Macromolecular crowding: qualitative and semiquantitative successes, quantitative challenges
    Damien Hall
    Section on Physical Biochemistry, Laboratory of Biochemistry and Genetics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD 20892 0830, USA
    Biochim Biophys Acta 1649:127-39. 2003
  5. ncbi request reprint The effects of Tubulin denaturation on the characterization of its polymerization behavior
    Damien Hall
    Section on Physical Biochemistry, Lab 222, Bld 8, National Institute of Diabetes, Digestive and Kidney Disease, National Institutes of Health, Bethesda, MD 20892, USA
    Biophys Chem 104:655-82. 2003
  6. ncbi request reprint Effects of inert volume-excluding macromolecules on protein fiber formation. I. Equilibrium models
    Damien Hall
    Section on Physical Biochemistry, Laboratory of Biochemistry and Genetics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Biophys Chem 98:93-104. 2002
  7. ncbi request reprint A toy model for predicting the rate of amyloid formation from unfolded protein
    Damien Hall
    Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB21EW, UK
    J Mol Biol 351:195-205. 2005
  8. ncbi request reprint Turbidity as a probe of tubulin polymerization kinetics: a theoretical and experimental re-examination
    Damien Hall
    Department of Chemistry, Cambridge University, Cambridge CB2 1EW, UK
    Anal Biochem 345:198-213. 2005
  9. ncbi request reprint Protein self-association in the cell: a mechanism for fine tuning the level of macromolecular crowding?
    Damien Hall
    Chemistry Department, University of Cambridge, Lensfield Road, Cambridge, CB21EW, UK
    Eur Biophys J 35:276-80. 2006
  10. ncbi request reprint Expanding to fill the gap: a possible role for inert biopolymers in regulating the extent of the 'macromolecular crowding' effect
    Damien Hall
    Chemistry Department, University of Cambridge, Lensfield Road, Cambridge CB21EW, United Kingdom
    FEBS Lett 580:2584-90. 2006

Detail Information

Publications10

  1. ncbi request reprint On the role of the macromolecular phase transitions in biology in response to change in solution volume or macromolecular composition: action as an entropy buffer
    Damien Hall
    Section on Physical Biochemistry, Laboratory of Biochemical Pharmacology, National Institute of Diabetes, Digestive and Kidney Diseases, National Institute of Health, Bethesda, MD 20892, USA
    Biophys Chem 98:233-48. 2002
    ..g. cytoskeletal elements such as tubulin and actin and possibly some prion structures) in response to cell volume change...
  2. ncbi request reprint Use of optical biosensors for the study of mechanistically concerted surface adsorption processes
    D Hall
    Section on Physical Biochemistry, National Institute of Diabetes, Digestive, and Kidney Disease, Bethesda, Maryland, 20892, USA
    Anal Biochem 288:109-25. 2001
    ..This Review focuses on pertinent aspects of the technology and its use for the performance and quantitative characterization of some various types of mechanistically concerted adsorption behavior...
  3. ncbi request reprint Effects of inert volume-excluding macromolecules on protein fiber formation. II. Kinetic models for nucleated fiber growth
    Damien Hall
    Section on Physical Biochemistry, Laboratory of Biochemistry and Genetics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA
    Biophys Chem 107:299-316. 2004
    ..In contrast, the rate of redistribution of fiber length, which occurs on a much slower time scale than polymer formation, is found to be insensitive to the extent of crowding...
  4. ncbi request reprint Macromolecular crowding: qualitative and semiquantitative successes, quantitative challenges
    Damien Hall
    Section on Physical Biochemistry, Laboratory of Biochemistry and Genetics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD 20892 0830, USA
    Biochim Biophys Acta 1649:127-39. 2003
    ..Recently suggested novel approaches to quantitative analysis of crowding phenomena, which may help to overcome some of the limitations of current theory, are summarized...
  5. ncbi request reprint The effects of Tubulin denaturation on the characterization of its polymerization behavior
    Damien Hall
    Section on Physical Biochemistry, Lab 222, Bld 8, National Institute of Diabetes, Digestive and Kidney Disease, National Institutes of Health, Bethesda, MD 20892, USA
    Biophys Chem 104:655-82. 2003
    ..It was also found that Tubulin denaturation may seriously distort parameter estimates gained from a kinetic characterization of the system (e.g. nucleus size and growth rate constant)...
  6. ncbi request reprint Effects of inert volume-excluding macromolecules on protein fiber formation. I. Equilibrium models
    Damien Hall
    Section on Physical Biochemistry, Laboratory of Biochemistry and Genetics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Biophys Chem 98:93-104. 2002
    ..It is found that the fractional (logarithmic) change in both solubility and in the breadth of the polymer size distribution scale almost linearly with the fractional (logarithmic) change in the thermodynamic activity of monomer...
  7. ncbi request reprint A toy model for predicting the rate of amyloid formation from unfolded protein
    Damien Hall
    Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB21EW, UK
    J Mol Biol 351:195-205. 2005
    ....
  8. ncbi request reprint Turbidity as a probe of tubulin polymerization kinetics: a theoretical and experimental re-examination
    Damien Hall
    Department of Chemistry, Cambridge University, Cambridge CB2 1EW, UK
    Anal Biochem 345:198-213. 2005
    ..4). We believe that the general findings and principles outlined here are applicable to studies of other fibril-forming systems that use turbidity as a marker of polymerization progress...
  9. ncbi request reprint Protein self-association in the cell: a mechanism for fine tuning the level of macromolecular crowding?
    Damien Hall
    Chemistry Department, University of Cambridge, Lensfield Road, Cambridge, CB21EW, UK
    Eur Biophys J 35:276-80. 2006
    ..In this communication we examine how the control of protein association/dissociation might influence one such important process, namely the folding of a protein to a compact state...
  10. ncbi request reprint Expanding to fill the gap: a possible role for inert biopolymers in regulating the extent of the 'macromolecular crowding' effect
    Damien Hall
    Chemistry Department, University of Cambridge, Lensfield Road, Cambridge CB21EW, United Kingdom
    FEBS Lett 580:2584-90. 2006
    ..This ability would confer on the non-reactive polymer a novel role in influencing other processes in solution affected by macromolecular crowding...