C R Haft

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi Characterization of Drosophila insulin receptor substrate
    R M Poltilove
    Diabetes Branch, NIDDKD, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Biol Chem 275:23346-54. 2000
  2. ncbi Identification of a family of sorting nexin molecules and characterization of their association with receptors
    C R Haft
    Diabetes Branch, National Institutes of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Mol Cell Biol 18:7278-87. 1998
  3. ncbi Human orthologs of yeast vacuolar protein sorting proteins Vps26, 29, and 35: assembly into multimeric complexes
    C R Haft
    Diabetes Branch, National Institutes of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892 1770, USA
    Mol Biol Cell 11:4105-16. 2000
  4. ncbi Overexpression of a novel sorting nexin, SNX15, affects endosome morphology and protein trafficking
    V A Barr
    Diabetes Branch, National Institutes of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Traffic 1:904-16. 2000
  5. ncbi Identification and characterization of SNX15, a novel sorting nexin involved in protein trafficking
    S A Phillips
    Diabetes Branch, NIDDK National Institutes of Health, Bethesda, MD 20892, USA
    J Biol Chem 276:5074-84. 2001
  6. ncbi Activation of serum- and glucocorticoid-induced protein kinase (Sgk) by cyclic AMP and insulin
    N Perrotti
    Diabetes Branch, Division of Intramural Research, NIDDK, Bethesda, Maryland 20892, USA
    J Biol Chem 276:9406-12. 2001

Collaborators

  • S A Phillips
  • S I Taylor
  • V A Barr
  • N Perrotti
  • R M Poltilove
  • D H Haft
  • R A He
  • A R Jacobs
  • P Xu

Detail Information

Publications6

  1. ncbi Characterization of Drosophila insulin receptor substrate
    R M Poltilove
    Diabetes Branch, NIDDKD, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Biol Chem 275:23346-54. 2000
    ..Taken together with published genetic studies, these biochemical data support the hypothesis that dIRS functions directly downstream from the insulin receptor in Drosophila...
  2. ncbi Identification of a family of sorting nexin molecules and characterization of their association with receptors
    C R Haft
    Diabetes Branch, National Institutes of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Mol Cell Biol 18:7278-87. 1998
    ..Our demonstration of a large conserved family of sorting nexins that interact with a variety of receptor types suggests that these proteins may be involved in several stages of intracellular trafficking in mammalian cells...
  3. ncbi Human orthologs of yeast vacuolar protein sorting proteins Vps26, 29, and 35: assembly into multimeric complexes
    C R Haft
    Diabetes Branch, National Institutes of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892 1770, USA
    Mol Biol Cell 11:4105-16. 2000
    ..In the absence of hVps35, neither hVps26 nor hVps29 is found in the large complex. These data provide the first insights into the binding interactions among subunits of a putative mammalian retromer complex...
  4. ncbi Overexpression of a novel sorting nexin, SNX15, affects endosome morphology and protein trafficking
    V A Barr
    Diabetes Branch, National Institutes of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Traffic 1:904-16. 2000
    ..Both the morphological and biochemical data indicate that SNX15 plays a crucial role in trafficking through the endocytic pathway. This is the first demonstration that a mammalian SNX protein is involved in protein trafficking...
  5. ncbi Identification and characterization of SNX15, a novel sorting nexin involved in protein trafficking
    S A Phillips
    Diabetes Branch, NIDDK National Institutes of Health, Bethesda, MD 20892, USA
    J Biol Chem 276:5074-84. 2001
    ....
  6. ncbi Activation of serum- and glucocorticoid-induced protein kinase (Sgk) by cyclic AMP and insulin
    N Perrotti
    Diabetes Branch, Division of Intramural Research, NIDDK, Bethesda, Maryland 20892, USA
    J Biol Chem 276:9406-12. 2001
    ..Cross-talk among these signaling pathways may play an important role in the pathogenesis of the hypertension associated with hyperinsulinemia, obesity, and insulin resistance...