Q Guo

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi Identification of a large Myc-binding protein that contains RCC1-like repeats
    Q Guo
    G W Hooper Foundation, University of California, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 95:9172-7. 1998
  2. ncbi Cardiac defects and altered ryanodine receptor function in mice lacking FKBP12
    W Shou
    Department of Pathology, Baylor College of Medicine, Houston, Texas 77030, USA
    Nature 391:489-92. 1998
  3. ncbi [The significance of the postburn expression of proto -- oncogenes c -- fos and c -- myc mRNA and proteins in rat myocardial cells]
    Q Guo
    Institute of Pathology, Southwestern Hos pital, The Third Military Medical University, Chongqing 400038, P.R. China
    Zhonghua Shao Shang Za Zhi 17:42-5. 2001
  4. ncbi Estradiol (E2) elicits SRC phosphorylation in the mouse neocortex: the initial event in E2 activation of the MAPK cascade?
    I S Nethrapalli
    Department of Anatomy and Cell Biology, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    Endocrinology 142:5145-8. 2001
  5. ncbi [Effect of free fatty acids on glucose transporter 4 and insulin signaling proteins in rat skeletal muscle cells]
    Q Guo
    Department of Endocrinology, First Hospital Affiliated to Peking University, Beijing 100034, China
    Zhonghua Yi Xue Za Zhi 81:866-7. 2001
  6. ncbi Characterization of nucleophosmin (B23) as a Myc target by scanning chromatin immunoprecipitation
    K I Zeller
    Program in Human Genetics and Molecular Biology and Department of Medicine, The Johns Hopkins Oncology Center and The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205
    J Biol Chem 276:48285-91. 2001
  7. ncbi A novel c-Myc-responsive gene, JPO1, participates in neoplastic transformation
    J E Prescott
    Program in Human Genetics and Molecular Biology, Department of Medicine, Johns Hopkins Oncology Center, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    J Biol Chem 276:48276-84. 2001
  8. ncbi Aberrant induction of Par-4 is involved in apoptosis of hippocampal neurons in presenilin-1 M146V mutant knock-in mice
    J Xie
    Department of Neurobiology and Pharmacology, Northeastern Ohio Universities College of Medicine, 4209 State Route 44, P O Box 95, Rootstown, OH 44272 0095, USA
    Brain Res 915:1-10. 2001
  9. ncbi Prostate apoptosis response-4 enhances secretion of amyloid beta peptide 1-42 in human neuroblastoma IMR-32 cells by a caspase-dependent pathway
    Q Guo
    Department of Neurobiology and Pharmacology, Northeastern Ohio Universities College of Medicine, Rootstown, Ohio 44272 0095, USA
    J Biol Chem 276:16040-4. 2001
  10. ncbi Smad5 knockout mice die at mid-gestation due to multiple embryonic and extraembryonic defects
    H Chang
    Departments of Pathology, Cell Biology and Molecular and Human Genetics, and Program in Developmental Biology, Baylor College of Medicine, Houston, TX, USA
    Development 126:1631-42. 1999

Collaborators

  • C V Dang
  • M P Mattson
  • Hong Chang
  • K S Korach
  • H Xiang
  • J E Prescott
  • K I Zeller
  • I S Nethrapalli
  • J F Barrett
  • J Xie
  • X Miao
  • F Yang
  • Y Huang
  • M Li
  • S Zhan
  • H Lin
  • W Shou
  • X Guan
  • R C Osthus
  • X Zhang
  • D B Lubahn
  • D R Wonsey
  • X Chang
  • C D Toran-Allerand
  • H Shim
  • L A Lee
  • A L Hawkins
  • T J Haggerty
  • C A Griffin
  • M Singh
  • B C Lewis
  • M J Charng
  • S Bao
  • B Aghdasi
  • M D Schneider
  • L M Mathews
  • D L Armstrong
  • M M Matzuk
  • S L Hamilton

Detail Information

Publications12

  1. ncbi Identification of a large Myc-binding protein that contains RCC1-like repeats
    Q Guo
    G W Hooper Foundation, University of California, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 95:9172-7. 1998
    ..The region in Myc required for binding to Pam includes a domain that is essential for the function of Myc and that is frequently mutated in Burkitt's lymphomas. PAM is located within a 300-kb region on chromosome 13q22...
  2. ncbi Cardiac defects and altered ryanodine receptor function in mice lacking FKBP12
    W Shou
    Department of Pathology, Baylor College of Medicine, Houston, Texas 77030, USA
    Nature 391:489-92. 1998
    ..Physiological studies demonstrate that FKBP12 is dispensable for TGF-beta-mediated signalling, but modulates the calcium release activity of both skeletal and cardiac ryanodine receptors...
  3. ncbi [The significance of the postburn expression of proto -- oncogenes c -- fos and c -- myc mRNA and proteins in rat myocardial cells]
    Q Guo
    Institute of Pathology, Southwestern Hos pital, The Third Military Medical University, Chongqing 400038, P.R. China
    Zhonghua Shao Shang Za Zhi 17:42-5. 2001
    ..This implied that there were different signal transduction and modulation mechanism among these pathological conditions...
  4. ncbi Estradiol (E2) elicits SRC phosphorylation in the mouse neocortex: the initial event in E2 activation of the MAPK cascade?
    I S Nethrapalli
    Department of Anatomy and Cell Biology, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    Endocrinology 142:5145-8. 2001
    ..Together, these data provide evidence that E2 activates a novel c-Src-dependent signal transduction pathway in the developing brain...
  5. ncbi [Effect of free fatty acids on glucose transporter 4 and insulin signaling proteins in rat skeletal muscle cells]
    Q Guo
    Department of Endocrinology, First Hospital Affiliated to Peking University, Beijing 100034, China
    Zhonghua Yi Xue Za Zhi 81:866-7. 2001
    ..05). CONCLUSION: Free fatty acids inhibit glucose metabolism and insulin activity in rat skeletal muscle cells by downregulating the expression of GLUT4 gene and protein and downregulating the protein expression of Grb2 and ERK2...
  6. ncbi Characterization of nucleophosmin (B23) as a Myc target by scanning chromatin immunoprecipitation
    K I Zeller
    Program in Human Genetics and Molecular Biology and Department of Medicine, The Johns Hopkins Oncology Center and The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205
    J Biol Chem 276:48285-91. 2001
    ..Hence, a scanning chromatin immunoprecipitation (SChIP) strategy is useful in analyzing functional transcription factor-binding sites...
  7. ncbi A novel c-Myc-responsive gene, JPO1, participates in neoplastic transformation
    J E Prescott
    Program in Human Genetics and Molecular Biology, Department of Medicine, Johns Hopkins Oncology Center, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    J Biol Chem 276:48276-84. 2001
    ....
  8. ncbi Aberrant induction of Par-4 is involved in apoptosis of hippocampal neurons in presenilin-1 M146V mutant knock-in mice
    J Xie
    Department of Neurobiology and Pharmacology, Northeastern Ohio Universities College of Medicine, 4209 State Route 44, P O Box 95, Rootstown, OH 44272 0095, USA
    Brain Res 915:1-10. 2001
    ....
  9. ncbi Prostate apoptosis response-4 enhances secretion of amyloid beta peptide 1-42 in human neuroblastoma IMR-32 cells by a caspase-dependent pathway
    Q Guo
    Department of Neurobiology and Pharmacology, Northeastern Ohio Universities College of Medicine, Rootstown, Ohio 44272 0095, USA
    J Biol Chem 276:16040-4. 2001
    ..These results suggest that Par-4 increases secretion of Abeta 1-42 largely through a caspase-dependent pathway after apoptotic cascades are initiated...
  10. ncbi Smad5 knockout mice die at mid-gestation due to multiple embryonic and extraembryonic defects
    H Chang
    Departments of Pathology, Cell Biology and Molecular and Human Genetics, and Program in Developmental Biology, Baylor College of Medicine, Houston, TX, USA
    Development 126:1631-42. 1999
    ..Despite the expression of Smad5 from gastrulation onwards, and in contrast to knockouts of Smad2 and Smad4, Smad5 only becomes essential later in extraembryonic and embryonic development...
  11. ncbi Par-4 is a mediator of neuronal degeneration associated with the pathogenesis of Alzheimer disease
    Q Guo
    Sanders Brown Research Center on Aging, University of Kentucky, Lexington 40536, USA
    Nat Med 4:957-62. 1998
    ..Par-4 expression was enhanced, and mitochondrial dysfunction and apoptosis exacerbated, in cells expressing presenilin-1 mutations associated with early-onset inherited AD...
  12. ncbi Fine mapping of E(kp)-1, a locus associated with silkworm (Bombyx mori) proleg development
    H Xiang
    Shanghai Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Center of Insect Science, The Chinese Academy of Sciences, Shanghai, P R China
    Heredity (Edinb) 100:533-40. 2008
    ..These results provide essential information for the isolation of this locus, which may shed light on the mechanism of proleg development in the silkworm and possibly in Lepidoptera...