Research Topics
Genomes and GenesSpecies | Marc J GunterSummaryAffiliation: National Institutes of Health Country: USA Publications
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Publications
Meat intake, cooking-related mutagens and risk of colorectal adenoma in a sigmoidoscopy-based case-control studyMarc J Gunter
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, EPS, 6120 Executive Boulevard, Rockville, MD 20852, USA
Carcinogenesis 26:637-42. 2005..49 (95% CI, 0.28-0.85)]. We did not identify any association with consumption of individual HCAs and colorectal adenoma risk. These results support the hypothesis that BP contributes to colorectal carcinogenesis...
Obesity and colorectal cancer: epidemiology, mechanisms and candidate genesMarc J Gunter
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD 20852, USA
J Nutr Biochem 17:145-56. 2006..These pathways will be discussed with particular reference to genetic polymorphisms that have been associated with obesity and insulin resistance...
A prospective study of serum C-reactive protein and colorectal cancer risk in menMarc J Gunter
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, Maryland 20852, USA
Cancer Res 66:2483-7. 2006..018). These results support the notion that chronic low-grade inflammation is a marker for increased risk of colorectal cancer...
Adipokine genes and prostate cancer riskSteven C Moore
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
Int J Cancer 124:869-76. 2009..05). Polymorphisms in the IL6, LEPR, TNF and ADIPOQ genes were not associated with prostate cancer. Allelic variants in the LEP gene are related to prostate cancer risk, supporting a role for leptin in prostate carcinogenesis...
Iron homeostasis and distal colorectal adenoma risk in the prostate, lung, colorectal, and ovarian cancer screening trialAmanda J Cross
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, MD 20852, USA
Cancer Prev Res (Phila) 4:1465-75. 2011....
Insulin resistance-related gene polymorphisms and risk of prostate cancerSteven C Moore
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland 20892, USA
Cancer Epidemiol Biomarkers Prev 16:1315-7. 2007
Caffeinated and decaffeinated coffee and tea intakes and risk of colorectal cancer in a large prospective studyRashmi Sinha
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, MD, USA
Am J Clin Nutr 96:374-81. 2012..Epidemiologic data for coffee and tea intakes in relation to colorectal cancer remain unclear. Despite differences in gut physiology, few studies have conducted investigations by anatomic subsites...
Iron and colorectal cancer risk in the alpha-tocopherol, beta-carotene cancer prevention studyAmanda J Cross
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, MD, USA
Int J Cancer 118:3147-52. 2006..7, 95% CI = 1.4-15.1, p trend = 0.009). In summary, we found a significant inverse association between several serum iron indices and colon cancer risk...
Leukocyte polycyclic aromatic hydrocarbon-DNA adduct formation and colorectal adenomaMarc J Gunter
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Division of Health and Human Services, Bethesda, MD 20852, USA
Carcinogenesis 28:1426-9. 2007..8 (95% CI, 1.2-6.5; P(trend) = 0.048) for risk of colorectal adenoma. These data support a link between PAH exposure and colorectal adenoma...
Common genetic variants and central adiposity among Asian-IndiansSteven C Moore
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland, USA
Obesity (Silver Spring) 20:1902-8. 2012....
Inflammation-related gene polymorphisms and colorectal adenomaMarc J Gunter
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland, USA
Cancer Epidemiol Biomarkers Prev 15:1126-31. 2006..7; 95% CI, 0.3-1.5; P(interaction) = 0.01). These exploratory data provide evidence that polymorphic variation in genes that regulate inflammation could alter risk for colorectal adenoma...
Insulin resistance-related genes and advanced left-sided colorectal adenomaMarc J Gunter
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland, USA
Cancer Epidemiol Biomarkers Prev 16:703-8. 2007....
Dietary benzo[a]pyrene intake and risk of colorectal adenomaRashmi Sinha
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Rockville, MD, USA
Cancer Epidemiol Biomarkers Prev 14:2030-4. 2005..21 (1.79-9.91) for the third quintile, 2.45 (0.98-6.12) for the fourth quintile, and 5.60 (2.20-14.20) for the fifth quintile (Ptrend=0.002). This study provides evidence that dietary BaP plays a role in colorectal adenoma etiology...
No association between cytochrome P450 and glutathione S-transferase gene polymorphisms and risk of colorectal adenoma: results from the UK Flexible Sigmoidoscopy Screening TrialMarc J Gunter
Dunn Human Nutrition Unit, Medical Research Council, MRC/Wellcome Trust Building, Hills Road, Cambridge CB2 2XY, United Kingdom
Cancer Epidemiol Biomarkers Prev 14:1028-30. 2005
A prospective evaluation of insulin and insulin-like growth factor-I as risk factors for endometrial cancerMarc J Gunter
Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York, NY 10461, USA
Cancer Epidemiol Biomarkers Prev 17:921-9. 2008..Free IGF-I levels were inversely associated with endometrioid adenocarcinoma, consistent with prior cross-sectional data...
MTHFR (C677T and A1298C) polymorphisms and risk of sporadic distal colorectal adenoma in the UK Flexible Sigmoidoscopy Screening Trial (United Kingdom)Panagiota N Mitrou
Dunn Human Nutrition Unit, MRC Wellcome Trust Building, Hills Road, Cambridge, CB2 2XY, UK
Cancer Causes Control 17:793-801. 2006..The purpose of this study was to further evaluate the role of low activity MTHFR variants as well as to explore interactive effects between alcoholic drink consumption and MTHFR variants and risk of distal colorectal adenomatous polyps...
Insulin, insulin-like growth factor-I, endogenous estradiol, and risk of colorectal cancer in postmenopausal womenMarc J Gunter
Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York 10461, USA
Cancer Res 68:329-37. 2008....
Role of NQO1C609T and EPHX1 gene polymorphisms in the association of smoking and alcohol with sporadic distal colorectal adenomas: results from the UKFSS StudyPanagiota N Mitrou
Dunn Human Nutrition Unit, MRC Wellcome Trust Building, Hills Road, Cambridge CB2 2XY, UK
Carcinogenesis 28:875-82. 2007..Alcohol increases risk of colorectal adenoma in carriers of the high-activity genotype possibly through enhanced activation of alcohol-related procarcinogens...
Associations of insulin-like growth factor (IGF)-I and IGF-binding protein-3 with HIV disease progression in womenHoward D Strickler
Albert Einstein College of Medicine, Bronx, New York 10461, USA
J Infect Dis 197:319-27. 2008....
