Research Topics
Species | K J GriffinSummaryAffiliation: National Institutes of Health Country: USA Publications
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Publications
A transgenic mouse bearing an antisense construct of regulatory subunit type 1A of protein kinase A develops endocrine and other tumours: comparison with Carney complex and other PRKAR1A induced lesionsK J Griffin
Section on Genetics and Endocrinology, Developmental Endocrinology Branch DEB, National Institute of Child Health and Human Development, Bethesda, MD 20892 1103, USA
J Med Genet 41:923-31. 2004....
A pleiomorphic GH pituitary adenoma from a Carney complex patient displays universal allelic loss at the protein kinase A regulatory subunit 1A (PRKARIA) locusI Bossis
Section on Genetics and Endocrinology, Developmental Endocrinology Branch, National Institute of Child Health and Human Development, Bethesda, MD 20892, USA
J Med Genet 41:596-600. 2004..Allelic loss may have occurred in a single precursor cell type that differentiated and clonally expanded into several phenotypes. Epithelial-to-mesenchymal transition may also occur in CNC-associated pleiomorphic pituitary adenomas...
Protein kinase A and its role in human neoplasia: the Carney complex paradigmI Bossis
Section on Endocrinology and Genetics, Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892-1862, USA
Endocr Relat Cancer 11:265-80. 2004..In this report, we review briefly the genetics of CNC and focus on the involvement of PRKAR1A in human tumorigenesis in an effort to reconcile the often diametrically opposite reports on R1alpha...
Molecular identification of spadetail: regulation of zebrafish trunk and tail mesoderm formation by T-box genesK J Griffin
Department of Biochemistry, Box 357350, University of Washington, Seattle, Washington 98195 7350, USA
Development 125:3379-88. 1998....
