Research Topics
Genomes and Genes
| Barry I GraubardSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
Risk of classic Kaposi sarcoma with exposures to plants and soils in SicilyJames J Goedert
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland, USA
Infect Agent Cancer 5:23. 2010..Ecologic and in vitro studies suggest that exposures to plants or soil may influence risk of Kaposi sarcoma (KS)...
Estimation of attributable number of deaths and standard errors from simple and complex sampled cohortsBarry I Graubard
Biostatistics Branch, National Cancer Institute, 6120 Executive Blvd, Room 8024, Bethesda, MD 20892, USA
Stat Med 26:2639-49. 2007..These methods can also be used to estimate the attributable number of cause-specific deaths and their standard errors when the time period for the accrual of deaths is short...
Five-year and lifetime risk of breast cancer among U.S. subpopulations: implications for magnetic resonance imaging screeningBarry I Graubard
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA
Cancer Epidemiol Biomarkers Prev 19:2430-6. 2010..Because MRI screening is costly and has limited specificity, estimates of the numbers of U.S. women with ≥20% breast cancer risk would be useful...
Standard errors for attributable risk for simple and complex sample designsBarry I Graubard
Biostatistics Branch, National Cancer Institute, 6120 Executive Boulevard, Room 8024, Bethesda, Maryland 20892, USA
Biometrics 61:847-55. 2005....
A cross-sectional investigation of regional patterns of diet and cardio-metabolic risk in IndiaCarrie R Daniel
Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Rockville, MD 20852, USA
Nutr J 10:12. 2011..The role of diet in India's rapidly progressing chronic disease epidemic is unclear; moreover, diet may vary considerably across North-South regions...
Genetic contributions to the association between adult height and testicular germ cell tumorsMichael B Cook
Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA, US
Int J Epidemiol 40:731-9. 2011..Recently, a number of single nucleotide polymorphisms (SNPs) have been found to be related to height. We examined whether these SNPs were associated with TGCT and whether they explained the relationship between height and TGCT...
Confirmation of family cancer history reported in a population-based surveyPhuong L Mai
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Blvd, EPS 7022, Rockville Pike, Bethesda, MD 20852, USA
J Natl Cancer Inst 103:788-97. 2011..However, it is not clear if reported family cancer history is sufficiently accurate for this purpose...
Caffeinated and decaffeinated coffee and tea intakes and risk of colorectal cancer in a large prospective studyRashmi Sinha
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, MD, USA
Am J Clin Nutr 96:374-81. 2012..Epidemiologic data for coffee and tea intakes in relation to colorectal cancer remain unclear. Despite differences in gut physiology, few studies have conducted investigations by anatomic subsites...
Risk of cancer in first- and second-degree relatives of testicular germ cell tumor cases and controlsVictoria M Chia
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
Int J Cancer 124:952-7. 2009..69, 95% CI: 0.51-0.94). Thus, this study suggests that there may be aggregation of cancer among families of men diagnosed with TGCT...
Dietary meat intake in relation to colorectal adenoma in asymptomatic womenLeah M Ferrucci
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
Am J Gastroenterol 104:1231-40. 2009....
Advanced glycation end products, soluble receptor for advanced glycation end products, and risk of colorectal cancerLi Jiao
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland, USA
Cancer Epidemiol Biomarkers Prev 20:1430-8. 2011..AGEs induce oxidative stress and inflammation via the receptor for AGEs (RAGE) and soluble RAGE (sRAGE) can neutralize the effects mediated by RAGE-ligand engagement...
Large prospective investigation of meat intake, related mutagens, and risk of renal cell carcinomaCarrie R Daniel
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, MD, USA
Am J Clin Nutr 95:155-62. 2012..The evidence for meat intake and renal cell carcinoma (RCC) risk is inconsistent. Mutagens related to meat cooking and processing, and variation by RCC subtype may be important to consider...
Socioeconomic deprivation impact on meat intake and mortality: NIH-AARP Diet and Health StudyJacqueline M Major
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, 6120 Executive Boulevard, Rockville, MD 20852, USA
Cancer Causes Control 22:1699-707. 2011..This study examined the impact of area socioeconomic deprivation on the association between meat intake and all-cause and cause-specific mortality after accounting for individual-level risk factors...
Multi-center feasibility study evaluating recruitment, variability in risk factors and biomarkers for a diet and cancer cohort in IndiaRashmi Sinha
National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD, USA
BMC Public Health 11:405. 2011..The aim of this feasibility study was to evaluate whether a diet-focused cohort study of cancer could be established in India, providing insight into potentially unique diet and lifestyle exposures...
Evidence that serum levels of the soluble receptor for advanced glycation end products are inversely associated with pancreatic cancer risk: a prospective studyLi Jiao
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
Cancer Res 71:3582-9. 2011..46 (0.23-0.73), P(trend) = 0.002]. Further adjustment for glucose or insulin levels did not change the observed associations. Our findings suggest that sRAGE is inversely associated with pancreatic cancer risk among Finnish male smokers...
Insulin-like growth factor 1, insulin-like growth factor-binding protein 3, and testicular germ-cell tumor riskVictoria M Chia
Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Executive Plaza South, Suite 550, 6120 Executive Boulevard, Rockville, MD 20892 7234, USA
Am J Epidemiol 167:1438-45. 2008..40, 1.09). Although there were no overall associations with insulin-like growth factor, contrary to expectation, there was a suggestion that IGF-1 concentrations may be inversely associated with risk of seminoma...
Polychlorinated biphenyls and risk of testicular germ cell tumorsKatherine A McGlynn
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland, USA
Cancer Res 69:1901-9. 2009..006), nonseminoma (P(trend) = 0.007), and seminoma (P(trend) = 0.05). Overall, these data do not support the hypothesis that PCB exposure increases the risk of TGCT...
Relationships of uterine and ovarian tumors to pre-existing chronic conditionsLouise A Brinton
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
Gynecol Oncol 107:487-94. 2007..Several chronic diseases have been hypothesized to affect the risk of subsequent gynecologic malignancies, possibly through shared hormonal mechanisms...
Neighborhood socioeconomic deprivation and mortality: NIH-AARP diet and health studyJacqueline M Major
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
PLoS ONE 5:e15538. 2010....
Socioeconomic status, healthcare density, and risk of prostate cancer among African American and Caucasian men in a large prospective studyJacqueline M Major
Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, MD 20852, USA
Cancer Causes Control 23:1185-91. 2012..The purpose of this study was to separately examine the impact of neighborhood socioeconomic deprivation and availability of healthcare resources on prostate cancer risk among African American and Caucasian men...
Perinatal factors and the risk of testicular germ cell tumorsMichael B Cook
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, MD 20892 7234, USA
Int J Cancer 122:2600-6. 2008..00-3.30) were risk factors. Nonseminoma was associated with breech birth (OR = 2.44, 95%CI: 1.25-4.78) and Cesarean section (OR = 2.10, 95%CI: 1.25-3.54). These results support the hypothesis that TGCT may originate in very early life...
Risk of testicular germ cell tumors and polymorphisms in the insulin-like growth factor genesVictoria M Chia
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, EPS Suite 550, 6120 Executive Boulevard, Rockville, MD 20892 7234, USA
Cancer Epidemiol Biomarkers Prev 17:721-6. 2008..There was a suggestion, however, that adult height may modify the relationship between an IGF-1 haplotype and TGCT risk. These results suggest that, in aggregate, genetic variation in IGF loci is not associated with TGCT risk...
A large prospective study of meat consumption and colorectal cancer risk: an investigation of potential mechanisms underlying this associationAmanda J Cross
Nutritional Epidemiology Branch, Biostatistics Branch, Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, NIH, Rockville, Maryland, USA
Cancer Res 70:2406-14. 2010..In conclusion, we found a positive association for red and processed meat intake and colorectal cancer; heme iron, nitrate/nitrite, and heterocyclic amines from meat may explain these associations...
Persistent organochlorine pesticides and risk of testicular germ cell tumorsKatherine A McGlynn
Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD 20852 7234, USA
J Natl Cancer Inst 100:663-71. 2008..Exposure to endocrine-disrupting chemicals, such as persistent organochlorine pesticides, has been suggested to increase the risk of testicular germ cell tumors (TGCTs)...
Maternal smoking and testicular germ cell tumorsKatherine A McGlynn
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, MD, USA
Cancer Epidemiol Biomarkers Prev 15:1820-4. 2006..Other early life exposures, however, may explain the familial clustering of lung cancer in mothers and TGCT in sons...
Adolescent and mid-life diet: risk of colorectal cancer in the NIH-AARP Diet and Health StudyElizabeth H Ruder
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, MD, USA
Am J Clin Nutr 94:1607-19. 2011..Colorectal cancer has a natural history of several decades; therefore, the diet consumed decades before diagnosis may aid in understanding this malignancy...
Socio-economic and other correlates of Kaposi sarcoma-associated herpesvirus seroprevalence among older adults in SicilyColleen Pelser
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland 20892, USA
J Med Virol 81:1938-44. 2009..3, CI 0.1-0.9). Other demographic and household variables were unrelated to seroprevalence. From these data, KSHV in Sicily appears to be related to low socio-economic status, but micro-endemicity in small communities cannot be excluded...
Genetic variants in the 8q24 locus and risk of testicular germ cell tumorsMichael B Cook
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD 20892 7234, USA
Hum Genet 123:409-18. 2008..In conclusion, this study has found little evidence for an association between the reported 8q24 SNPs and TGCTs, although the findings for nonseminoma may be worth further investigation...
Prospective study of alcohol consumption quantity and frequency and cancer-specific mortality in the US populationRosalind A Breslow
Division of Epidemiology and Prevention Research, National Institute on Alcohol Abuse and Alcoholism, 5635 Fishers Lane, Room 2071, Bethesda, MD 20892, USA
Am J Epidemiol 174:1044-53. 2011..03) and tended to be associated with increased risk of breast cancer (RR = 1.44, 95% CI: 0.96, 2.17; P-trend = 0.06). Epidemiologic studies of alcohol and cancer mortality should consider the independent effects of quantity and frequency...
Meat and components of meat and the risk of bladder cancer in the NIH-AARP Diet and Health StudyLeah M Ferrucci
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland, USA
Cancer 116:4345-53. 2010..The authors comprehensively investigated the association between meat and meat components and bladder cancer...
Meat-related mutagen exposure, xenobiotic metabolizing gene polymorphisms and the risk of advanced colorectal adenoma and cancerAnne M J Gilsing
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services Bethesda, MD, USA
Carcinogenesis 33:1332-9. 2012..This large and comprehensive study of XME genes, meat mutagens and the risk of colorectal tumours found that a NAT1 polymorphism modified the association between MeIQx intake and colorectal adenoma risk...
Meat intake is not associated with risk of non-Hodgkin lymphoma in a large prospective cohort of U.S. men and womenCarrie R Daniel
National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD, USA
J Nutr 142:1074-80. 2012..In this large U.S. cohort, meat intake was not associated with NHL or any histologic subtypes of NHL. Contrary to findings in animal models and other cancer sites, meat-cooking and -processing compounds did not increase NHL risk...
Prospective investigation of poultry and fish intake in relation to cancer riskCarrie R Daniel
Nutritional Epidemiology Branch, National Cancer Institute, NIH, Department of Health and Human Services, 6120 Executive Blvd, Suite 320, Rockville, MD 20852, USA
Cancer Prev Res (Phila) 4:1903-11. 2011..Simply increasing fish or poultry intake, without reducing red meat intake, may be less beneficial for cancer prevention...
Hypertension and risk of renal cell carcinoma among white and black AmericansJoanne S Colt
Division of Cancer Epidemiology and Genetics, Occupational and Environmental Epidemiology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 7240, USA
Epidemiology 22:797-804. 2011..We investigated the hypertension-renal cancer association by race, and we assessed the role of hypertension in the racial disparity of renal cancer incidence...
Patterns of meat intake and risk of prostate cancer among African-Americans in a large prospective studyJacqueline M Major
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, 6120 Executive Boulevard, Rockville, MD 20852, USA
Cancer Causes Control 22:1691-8. 2011..The purpose of this study was to examine the association between type of meat intake and prostate cancer risk among African-American men...
Genetic variation in hormone metabolizing genes and risk of testicular germ cell tumorsJonine D Figueroa
Department of Health and Human Services, National Cancer Institute, Bethesda, MD, USA
Cancer Causes Control 19:917-29. 2008..02. Caution in interpretation is warranted until findings are replicated in other studies; however, the results suggest that genetic variation in CYP1A1 may be associated with nonseminoma...
Serum levels of vitamin D metabolites and breast cancer risk in the prostate, lung, colorectal, and ovarian cancer screening trialD Michal Freedman
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, MD 20892 7238, USA
Cancer Epidemiol Biomarkers Prev 17:889-94. 2008....
Genetic variation in the inhibin pathway and risk of testicular germ cell tumorsMark P Purdue
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, MD 20892, USA
Cancer Res 68:3043-8. 2008..89-2.99; TT: OR, 4.54; 95% CI 2.00-10.3; P(trend) = 0.0008). We found no evidence of association with variants in the other investigated genes. These findings suggest that genetic variation in the INHA locus influences TGCT development...
Serum 25-hydroxyvitamin D and cancer mortality in the NHANES III study (1988-2006)D Michal Freedman
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland 20892 7238, USA
Cancer Res 70:8587-97. 2010..These findings argue for caution before increasing 25(OH)D levels to prevent cancer...
Human herpesvirus 8 seroprevalence among children and adolescents in the United StatesLesley A Anderson
Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA
Pediatr Infect Dis J 27:661-4. 2008..4%). K8.1 seropositivity was associated with asthma (odds ratio: 6.3; 95% confidence interval: 2.4-16.9) and hay fever (3.5; 1.1-11.0), and there were borderline associations with measures of crowding and low socioeconomic status...
Dichlorodiphenyltrichloroethane and risk of hepatocellular carcinomaE Christina Persson
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
Int J Cancer 131:2078-84. 2012..96 95% CI; 1.19-7.40. There were no statistically significant associations with p,p'-DDE. Overall, these results suggest that recent exposure to p,p'-DDT may increase risk of HCC...
Data and trends in cancer screening in the United States: results from the 2005 National Health Interview SurveyJudith Swan
Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, Maryland, USA
Cancer 116:4872-81. 2010..We also examine trends from 1992 through 2005 to determine whether differences in screening use are increasing, staying the same, or decreasing...
Metabolic syndrome increases the risk of primary liver cancer in the United States: a study in the SEER-Medicare databaseTania M Welzel
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
Hepatology 54:463-71. 2011..96-2.31, P<0.0001) and ICC (odds ratio=1.56; 95% confidence interval=1.32-1.83, P<0.0001). CONCLUSION: Metabolic syndrome is a significant risk factor for development of HCC and ICC in the general U.S. population...
A case-control investigation of immune function gene polymorphisms and risk of testicular germ cell tumorsMark P Purdue
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, EPS 8009, 6120 Executive Boulevard, Rockville, MD 20892 7234, USA
Cancer Epidemiol Biomarkers Prev 16:77-83. 2007..In conclusion, our findings suggest that polymorphisms in TGFB1 and LTA/TNF, and possibly other immune function genes, may influence susceptibility to TGCT...
Coherence and completeness of population-based family cancer reportsLouise Wideroff
National Cancer Institute, Bethesda, Maryland, USA
Cancer Epidemiol Biomarkers Prev 19:799-810. 2010..Given its widespread use in cancer screening and surveillance, better information is needed about the clarity and accuracy of family history information reported in the general population...
Body size, dairy consumption, puberty, and risk of testicular germ cell tumorsKatherine A McGlynn
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892 7234, USA
Am J Epidemiol 165:355-63. 2007..As adult height is largely determined in the first 2 years of life, increased attention to events in this interval may help elucidate the etiology of TGCTs...
Non-steroidal anti-inflammatory drugs and colorectal cancer risk in a large, prospective cohortElizabeth H Ruder
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland, USA
Am J Gastroenterol 106:1340-50. 2011..We investigated NSAID use and colorectal adenocarcinoma by subsite, and among individuals with a family history of colon cancer in the National Institutes of Health-AARP Diet and Health Study...
The association between chronic renal failure and renal cell carcinoma may differ between black and white AmericansJonathan N Hofmann
Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Bethesda, MD 20892 7240, USA
Cancer Causes Control 24:167-74. 2013..Risk of RCC is elevated among end-stage renal disease patients, although no studies have looked at differences by race in the relationship between chronic renal failure and RCC...
Placental characteristics as a proxy measure of serum hormone and protein levels during pregnancy with a male fetusBritton Trabert
Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, 6120 Executive Boulevard, Suite 550, Rockville, MD 20852 7234, USA
Cancer Causes Control 22:689-95. 2011..Associations with birth weight were also examined...
Testing Hardy-Weinberg equilibrium and homogeneity of Hardy-Weinberg disequilibrium using complex survey dataYan Li
Biostatistics Branch, National Cancer Institute, 6120 Executive Boulevard, Room 8014, Rockville, Maryland 20852, USA
Biometrics 65:1096-104. 2009..Rao-Scott corrections applied to the tests were found to improve their type I error properties. Our methods are applied to the NHANES III genetic data for three loci involved in metabolizing lead in the body...
Maternal hormone levels and perinatal characteristics: implications for testicular cancerYawei Zhang
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health DHHS, 6120 Executive Boulevard, Rockville, MD 20852, USA
Ann Epidemiol 17:85-92. 2007..To examine the hypothesis, some studies used perinatal factors as surrogates for hormone levels. To determine the validity of this assumption, hormone-perinatal factor relationships were examined in the Collaborative Perinatal Project...
Meat and meat-related compounds and risk of prostate cancer in a large prospective cohort study in the United StatesRashmi Sinha
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892, USA
Am J Epidemiol 170:1165-77. 2009..There were no clear associations for fatal prostate cancer. Red and processed meat may be positively associated with prostate cancer via mechanisms involving heme iron, nitrite/nitrate, grilling/barbecuing, and benzo[a]pyrene...
Serum C-reactive protein and risk of pancreatic cancer in two nested, case-control studiesJason B Douglas
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Rockville, Maryland, USA
Cancer Epidemiol Biomarkers Prev 20:359-69. 2011..Many epidemiologic studies have examined the association between C-reactive protein (CRP) and risk of cancer with inconsistent results...
A combined healthy lifestyle score and risk of pancreatic cancer in a large cohort studyLi Jiao
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD 20852, USA
Arch Intern Med 169:764-70. 2009..We generated a healthy lifestyle score to investigate their joint effect on risk of pancreatic cancer...
Risk factors for cryptorchism among populations at differing risks of testicular cancerKatherine A McGlynn
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, MD 20852, USA
Int J Epidemiol 35:787-95. 2006..However, while TGCT incidence varies greatly between white and black men, little variability has been reported between the two groups in cryptorchism prevalence. This may suggest that cryptorchism risk factors differ by ethnicity...
Which women aren't getting mammograms and why? (United States)Helen I Meissner
Applied Cancer Screening Research Branch, Division of Cancer Control and Population Sciences, National Cancer Institute, 6130 Executive Blvd, EPN 4102 MSC 7331, Bethesda, MD 20892 7331, USA
Cancer Causes Control 18:61-70. 2007..This study investigates why women who reported no recent mammogram did not get the test...
Gender-specific differences in birthweight and the odds of puberty: NHANES III, 1988-94Susan Olivo-Marston
The Laboratory of Human Carcinogenesis, Division of Cancer Prevention, The National Cancer Institute, The National Institutes of Health, Bethesda, MD, USA
Paediatr Perinat Epidemiol 24:222-31. 2010..Our findings need replication in prospective longitudinal studies, and research to understand the mechanisms underlying the relation of early life exposures to cancer risk...
Prospective study of serum vitamin D and cancer mortality in the United StatesD Michal Freedman
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Executive Plaza South Rm 7036, 6120 Executive Blvd, Bethesda, MD 20892 7238, USA
J Natl Cancer Inst 99:1594-602. 2007..Epidemiologic studies of the association of 25-hydroxyvitamin D [25(OH)D] and the risk of cancer, however, have been largely limited to incident cancers at a few sites...
Alcoholic beverage consumption, nutrient intakes, and diet quality in the US adult population, 1999-2006Rosalind A Breslow
National Institute on Alcohol Abuse and Alcoholism, Division of Epidemiology and Prevention Research, 5635 Fishers Ln, Rm 2071, Rockville, MD 20892, USA
J Am Diet Assoc 110:551-62. 2010..Little is known about associations between alcoholic beverage consumption, nutrient intakes, and diet quality, although each has been independently associated with chronic disease outcomes...
A case-control study of occupation/industry and renal cell carcinoma riskSara Karami
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, 6120 Executive Boulevard, MSC 7242, Bethesda, MD 20892 7242, USA
BMC Cancer 12:344. 2012..Here, we investigated associations between employment in specific occupations and industries and RCC, and its most common histologic subtype, clear cell RCC (ccRCC)...
Social and physical environments of sports and exercise reported among adults in the American Time Use SurveyGenevieve Fridlund Dunton
Health Promotion Research Branch, Behavioral Research Program, Division of Cancer Control and Population Sciences National Cancer Institute, 6130 Executive Blvd EPN 4051C, MSC 7365, Bethesda, MD 20892 7365, USA
Prev Med 47:519-24. 2008..Demographic and temporal patterns in the social and physical environments of sports and exercise in the American Time Use Survey (years 2003-2006) are described...
Reverse causation and illness-related weight loss in observational studies of body weight and mortalityKatherine M Flegal
National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, Maryland, USA
Am J Epidemiol 173:1-9. 2011..Further research would be useful to elucidate the potential effects and importance of reverse causation or illness-related weight loss as a source of bias in the observed associations between weight and mortality in cohort studies...
Benefit/risk assessment for breast cancer chemoprevention with raloxifene or tamoxifen for women age 50 years or olderAndrew N Freedman
Division of Cancer Prevention, National Cancer Institute, 6130 Executive Blvd, Bethesda, MD 20892, USA
J Clin Oncol 29:2327-33. 2011..There is a need to summarize the risks and benefits of these agents...
Insulin resistance-related gene polymorphisms and risk of prostate cancerSteven C Moore
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Bethesda, Maryland 20892, USA
Cancer Epidemiol Biomarkers Prev 16:1315-7. 2007
Serum selenium and risk of prostate cancer in U.S. blacks and whitesTara M Vogt
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892-7246, USA
Int J Cancer 103:664-70. 2003..S. blacks. Since selenium exposure varies widely throughout the world, further research on optimal concentrations for cancer prevention is justified...
Application of nonparametric quantile regression to body mass index percentile curves from survey dataYan Li
Biostatistics Branch, National Cancer Institute, Bethesda, MD 20892, USA
Stat Med 29:558-72. 2010..Using this procedure we re-estimate the national percentile BMI-for-age curves and the prevalence of high-BMI children in the U.S...
Prevalence of tamoxifen use for breast cancer chemoprevention among U.S. womenErika A Waters
Cancer Prevention Fellowship Program, Center for Cancer Training, Health Communication and Informatics Research Branch Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, Maryland, USA
Cancer Epidemiol Biomarkers Prev 19:443-6. 2010..Tamoxifen can reduce the risk of developing invasive estrogen receptor-positive breast cancer by 49%, but it is unknown how many women in the United States are taking tamoxifen for primary prevention of breast cancer...
Understanding the factors underlying disparities in cancer screening rates using the Peters-Belson approach: results from the 1998 National Health Interview SurveyR Sowmya Rao
Biostatistics Branch, Division of Cancer Epidemiology and Genetics, Applied Research Program, National Cancer Institute, Department of Health and Human Services, Bethesda, Maryland 20892, USA
Med Care 42:789-800. 2004..Knowing how much of a health disparity is explained by measured covariates can be used to develop more effective interventions and policies to eliminate disparity...
Racial differences in serum selenium concentration: analysis of US population data from the Third National Health and Nutrition Examination SurveyTara M Vogt
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
Am J Epidemiol 166:280-8. 2007..0001). The observation that Blacks had lower unadjusted and adjusted serum selenium concentrations relative to Whites is intriguing, given the racial disparity in incidence of prostate cancer and other cancers...
Increasing incidence of testicular germ cell tumors among black men in the United StatesKatherine A McGlynn
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, 6120 Executive Blvd, Rm 7060, Rockville, MD 20852 7234, USA
J Clin Oncol 23:5757-61. 2005..However, a recent examination of ethnic-specific rates suggested that the incidence among black men may have begun to change in the 1990s...
Estimates of the number of US women who could benefit from tamoxifen for breast cancer chemopreventionAndrew N Freedman
Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 7344, USA
J Natl Cancer Inst 95:526-32. 2003..67% or higher for breast cancer chemoprevention. However, tamoxifen use has been associated with adverse outcomes, and not all eligible women have a positive benefit/risk ratio...
Covariate adjustment and ranking methods to identify regions with high and low mortality ratesHuilin Li
Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Executive Plaza South, RM 8034, Bethesda, Maryland 20892, USA
Biometrics 66:613-20. 2010..However, for diseases with smaller event counts, such as cancers, and wide variation in event counts among regions, EB and PPR methods outperform ranking based on SMRs...
Maternal pregnancy levels of polychlorinated biphenyls and risk of hypospadias and cryptorchidism in male offspringKatherine A McGlynn
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health DHHS, 6120 Executive Blvd, Rockville, MD 20852 7234, USA
Environ Health Perspect 117:1472-6. 2009..It has been suggested, however, that in utero hormone levels may be related to risk. Endocrine-disrupting chemicals, including polychlorinated biphenyl (PCB) compounds, may alter hormone levels and thereby affect the fetus...
An application of a weighting method to adjust for nonresponse in standardized incidence ratio analysis of cohort studiesR Sowmya Rao
Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, DHHS, Bethesda, MD 20892 7244, USA
Ann Epidemiol 15:129-36. 2005..We propose an analytic approach to reduce the impact of nonresponse in the analyses of SIRs...
The association of blood lead level and cancer mortality among whites in the United StatesAhmedin Jemal
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland, USA
Environ Health Perspect 110:325-9. 2002..In conclusion, individuals with blood lead levels in the range of NHANES II do not appear to have increased risk of cancer mortality...
Maternal hormone levels and risk of cryptorchism among populations at high and low risk of testicular germ cell tumorsKatherine A McGlynn
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, 6120 Executive Boulevard, EPS 7060, Rockville, MD 20852, USA
Cancer Epidemiol Biomarkers Prev 14:1732-7. 2005..05). These results do not support either the estrogen or the androgen hypothesis. Rather, lower estrogens in case mothers may indicate that a placental defect increases the risk of cryptorchism and, possibly, testicular cancer...
Toenail selenium and risk of hepatocellular carcinoma mortality in Haimen City, ChinaLori C Sakoda
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institute of Health, Department of Health and Human Services, Rockville, MD 20852, USA
Int J Cancer 115:618-24. 2005....
Relationship of benign gynecologic diseases to subsequent risk of ovarian and uterine tumorsLouise A Brinton
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Room 7068, 6120 Executive Boulevard, Rockville, MD 20852 7234, USA
Cancer Epidemiol Biomarkers Prev 14:2929-35. 2005..Although endometriosis and uterine leiomyomas are common conditions, the extent to which either is associated with certain types of malignancies remains uncertain...
Prospective study of alcohol consumption in the United States: quantity, frequency, and cause-specific mortalityRosalind A Breslow
Division of Epidemiology and Prevention Research, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Rockville, MD 20892, USA
Alcohol Clin Exp Res 32:513-21. 2008..Alcohol average volume (quantity multiplied by frequency) has been associated with mortality in drinkers. However, average volume may mask associations due to quantity or frequency alone...
A sensitivity analysis for nonrandomly missing categorical data arising from a national health disability surveyStuart G Baker
Biometry Research Group, Division of Cancer Prevention, National Cancer Institute, EPN 3131, 6130 Executive Blvd MSC 7354, Bethesda, MD 20892 7354, USA
Biostatistics 4:41-56. 2003..2 with 95% CI of (3.9, 4.6). Under one nonignorable missing-data model, the odds ratio was 7.4 with 95% CI of (6.3, 8.6). This is the first analysis to find a strong association between balance difficulties and frequent depression...
Testing logistic regression coefficients with clustered data and few positive outcomesSally Hunsberger
Biometric Research Branch, National Cancer Institute, Bethesda, MD 20892, U S A
Stat Med 27:1305-24. 2008..The proposed method is also useful when testing goodness-of-fit of logistic regression models using deciles-of-risk tables...
Evaluation of three retrospective exposure assessment methodsPatricia A Stewart
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, 6120 Executive Boulevard, MSC 7240, Rockville, MD 20892 7240, USA
Ann Occup Hyg 47:399-411. 2003..To evaluate three methods for assessing retrospective exposures of acrylonitrile workers...
Risk factors for human herpesvirus 8 infection among adults in the United States and evidence for sexual transmissionEric A Engels
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Rockville, MD 20892, USA
J Infect Dis 196:199-207. 2007..Human herpesvirus 8 (HHV-8) causes Kaposi sarcoma. In the United States, transmission routes for HHV-8 are uncertain...
Meat intake and mortality: a prospective study of over half a million peopleRashmi Sinha
Division of Cancer Epidemiology and Genetics, National Cancer Institute Nutritional Epidemiology Branch, Rockville, MD 20852, USA
Arch Intern Med 169:562-71. 2009..High intakes of red or processed meat may increase the risk of mortality. Our objective was to determine the relations of red, white, and processed meat intakes to risk for total and cause-specific mortality...
Insulin, glucose, insulin resistance, and pancreatic cancer in male smokersRachael Z Stolzenberg-Solomon
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Rockville, MD 20852, USA
JAMA 294:2872-8. 2005..Obesity, diabetes mellitus, and glucose intolerance have been associated with increased pancreatic cancer risk; however, prediagnostic serum insulin concentration has not been evaluated as a predictor of this malignancy...
Childhood tumor risk after treatment with ovulation-stimulating drugsLouise A Brinton
Division of Cancer Epidemiology, National Cancer Institute, Bethesda, Maryland, USA
Fertil Steril 81:1083-91. 2004..To assess childhood cancer risk among children conceived following the use of ovulation-stimulating drugs...
Measurement of spices and seasonings in India: opportunities for cancer epidemiology and preventionLeah M Ferrucci
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD, USA
Asian Pac J Cancer Prev 11:1621-9. 2010....
Population estimates of extended family structure and sizeAnne Garceau
Division of Cancer Control and Population Sciences, Risk Factor Monitoring and Methods Branch, National Cancer Institute, Bethesda, MD 20892, USA
Community Genet 11:331-42. 2008..Population-based estimates of biological family size can be useful for planning genetic studies, assessing how distributions of relatives affect disease associations with family history and estimating prevalence of potential family support...
Environmental influences on exercise intensity and duration in a U.S. time use studyGenevieve F Dunton
Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD
Med Sci Sports Exerc 41:1698-705. 2009..The current study investigated whether the intensity and duration of sports and exercise bouts differ across physical and social environments as reported in a nationally representative time use survey of U.S. adults...
Risk factors for intrahepatic and extrahepatic cholangiocarcinoma in the United States: a population-based case-control studyTania M Welzel
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
Clin Gastroenterol Hepatol 5:1221-8. 2007..Because the etiology of both tumors is poorly understood, a population-based case-control study was conducted to examine the association of ECC and ICC with preexisting medical conditions...
Aspirin use and mortality from cancer in a prospective cohort studyLuke D Ratnasinghe
Division of Molecular Epidemiology, NCTR, Food and Drug Administration, Jefferson, Arkansas 72079, USA
Anticancer Res 24:3177-84. 2004..The purpose of this study was to assess the association between aspirin use and death from cancer and cardiovascular diseases with a special emphasis on cancer mortality...
Fraction of premature deaths in the Canadian population that were attributable to overweight and obesityKatherine M Flegal
Can J Public Health 95:235; author reply 235. 2004
Fruit and vegetable intake and prevalence of colorectal adenoma in a cancer screening trialAmy E Millen
University at Buffalo, School of Public Health and Health Professions, Department of Social and Preventive Medicine, Buffalo, NY 14214 8001, USA
Am J Clin Nutr 86:1754-64. 2007..Research on the association between fruit and vegetable intake and risk of colorectal adenoma is inconclusive...
Population-density and county-level variation in breast cancer mortality rates among white women residing in the Northeastern and Southern United StatesSusan R Sturgeon
Department of Biostatistics and Epidemiology, School of Public Health and Health Sciences, University of Massachusetts, Amherst, MA 01003, USA
Cancer Causes Control 14:923-31. 2003..We assessed the contribution of variation in risk factor prevalence to population-density and county-level variation in breast cancer mortality rates...
Secular trends in the association of socio-economic position with self-reported dietary attributes and biomarkers in the US population: National Health and Nutrition Examination Survey (NHANES) 1971-1975 to NHANES 1999-2002Ashima K Kant
Department of Family, Nutrition, and Exercise Sciences, Remsen Hall, Room 306E, Queens College of City University of New York, Flushing, NY 11367, USA
Public Health Nutr 10:158-67. 2007..To understand if diet may be a contributor to these trends, we examined secular trends in the association of diet and indicators of SEP from 1971-1975 to 1999-2002...
Predictors of reported consumption of low-nutrient-density foods in a 24-h recall by 8-16 year old US children and adolescentsAshima K Kant
Department of Family, Nutrition, and Exercise Sciences, Queens College of the City University of New York, Flushing, NY 11367, USA
Appetite 41:175-80. 2003..Socio-demographic, family, body weight, or lifestyle characteristics contributed little to predicting the number of LND foods reported in a 24-h recall...
Correcting bias, or biased corrections?Katherine M Flegal
National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, MD, USA
Obesity (Silver Spring) 16:229-31. 2008
Obesity and cancerKatherine M Flegal
N Engl J Med 349:502-4; author reply 502-4. 2003
Ethnic and socioeconomic differences in variability in nutritional biomarkersAshima K Kant
Department of Family, Nutrition, and Exercise Sciences, Queens College of the City University of New York, Flushing, NY 11367, USA
Am J Clin Nutr 87:1464-71. 2008..Although biomarker measurements are not subject to biased self-reports, biologic variability due to individual characteristics and behaviors related to dietary exposures contributes to within-subject variability and measurement error...
Diet and risk of adult glioma in eastern Nebraska, United StatesHonglei Chen
Tufts University, Human Nutrition Research Center on Aging, Boston, MA, USA
Cancer Causes Control 13:647-55. 2002..CONCLUSION: Our study does not support the N-nitroso compound hypothesis, but suggests potential roles for carotenoids and possibly other phytochemicals in reducing risk of adult glioma...
Weight-associated deaths in the United StatesKatherine M Flegal
J Womens Health (Larchmt) 16:1368-70. 2007
