Andy Golden

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc emb-1 encodes the APC16 subunit of the Caenorhabditis elegans anaphase-promoting complex
    Diane C Shakes
    Department of Biology, College of William and Mary, Williamsburg, Virginia, USA
    Genetics 189:549-60. 2011
  2. ncbi request reprint Silence is golden: combining RNAi and live cell imaging to study cell cycle regulatory genes during Caenorhabditis elegans development
    Andy Golden
    Laboratory of Biochemistry and Genetics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 8 Center Dr Bethesda, MD 20892, USA
    Methods 41:190-7. 2007
  3. pmc The C. elegans Myt1 ortholog is required for the proper timing of oocyte maturation
    Anna E Burrows
    Laboratory of Biochemistry and Genetics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 8 Center Drive, Building 8, Room 323, Bethesda, MD 20892, USA
    Development 133:697-709. 2006
  4. pmc Components of the spindle assembly checkpoint regulate the anaphase-promoting complex during meiosis in Caenorhabditis elegans
    Kathryn K Stein
    Laboratory of Biochemistry and Genetics, NIDDK, National Institutes of Health, Bethesda, Maryland 20892, USA
    Genetics 175:107-23. 2007
  5. pmc Protein phosphatase 5 is a negative regulator of separase function during cortical granule exocytosis in C. elegans
    Christopher T Richie
    Laboratory of Biochemistry and Genetics, NIDDK, NIH, Bethesda, MD 20892, USA
    J Cell Sci 124:2903-13. 2011
  6. pmc Developmental defects observed in hypomorphic anaphase-promoting complex mutants are linked to cell cycle abnormalities
    Diane C Shakes
    Department of Biology, College of William and Mary, Williamsburg, Virginia 23187, USA
    Development 130:1605-20. 2003
  7. pmc Inactivation of the C. elegans lipin homolog leads to ER disorganization and to defects in the breakdown and reassembly of the nuclear envelope
    Andy Golden
    The Laboratory of Biochemistry and Genetics and National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 8 Center Drive, Bethesda, MD 20892, USA
    J Cell Sci 122:1970-8. 2009
  8. pmc Functional redundancy of paralogs of an anaphase promoting complex/cyclosome subunit in Caenorhabditis elegans meiosis
    Kathryn K Stein
    Laboratory of Biochemistry and Genetics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Genetics 186:1285-93. 2010
  9. ncbi request reprint Getting (chromosomes) loaded--a new role for timeless
    Andy Golden
    Laboratory of Biochemistry and Genetics, NIDDK, NIH, Bethesda, MD 20892, USA
    Dev Cell 5:7-9. 2003
  10. doi request reprint Confocal imaging of the microtubule cytoskeleton in C. elegans embryos and germ cells
    KEVIN F O'CONNELL
    Laboratory of Biochemistry and Genetics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA
    Methods Mol Biol 1075:257-72. 2014

Collaborators

  • Diane C Shakes
  • Jun Liu
  • JOSHUA N BEMBENEK
  • Christopher T Richie
  • Kathryn K Stein
  • KEVIN F O'CONNELL
  • Edward S Davis
  • Akilah Moore
  • Jill M Schumacher
  • Anna E Burrows
  • Penny L Sadler
  • Neville Ashcroft
  • Diane G Morton
  • Barry Chestnut
  • MATTHEW WALLENFANG
  • Tokiko Furuta
  • Benjamin D Ross
  • Jessica E Nesmith
  • Thomas Hays
  • Mary E Kosinski
  • Bonnielin K Sceurman
  • Staci Nugent
  • Daryl Dichoso
  • Barry A Chestnut
  • Wenfu Wang
  • Kenneth J Kemphues
  • Lucia Wille

Detail Information

Publications16

  1. pmc emb-1 encodes the APC16 subunit of the Caenorhabditis elegans anaphase-promoting complex
    Diane C Shakes
    Department of Biology, College of William and Mary, Williamsburg, Virginia, USA
    Genetics 189:549-60. 2011
    ..In addition to its meiotic function, emb-1 is required for mitotic proliferation of the germline. These studies reveal that emb-1 encodes K10D2.4, a homolog of the small, recently discovered APC/C subunit, APC16...
  2. ncbi request reprint Silence is golden: combining RNAi and live cell imaging to study cell cycle regulatory genes during Caenorhabditis elegans development
    Andy Golden
    Laboratory of Biochemistry and Genetics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 8 Center Dr Bethesda, MD 20892, USA
    Methods 41:190-7. 2007
    ..Here we discuss experimental approaches for studying cell cycle processes in the nematode Caenorhabditis elegans...
  3. pmc The C. elegans Myt1 ortholog is required for the proper timing of oocyte maturation
    Anna E Burrows
    Laboratory of Biochemistry and Genetics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 8 Center Drive, Building 8, Room 323, Bethesda, MD 20892, USA
    Development 133:697-709. 2006
    ..Furthermore, co-depletion studies of CDK-1 and WEE-1.3 demonstrate that WEE-1.3 is dispensable in the absence of CDK-1, suggesting that CDK-1 is a major target of WEE-1.3 in C. elegans oocytes...
  4. pmc Components of the spindle assembly checkpoint regulate the anaphase-promoting complex during meiosis in Caenorhabditis elegans
    Kathryn K Stein
    Laboratory of Biochemistry and Genetics, NIDDK, National Institutes of Health, Bethesda, Maryland 20892, USA
    Genetics 175:107-23. 2007
    ..These studies provide evidence that components of the spindle assembly checkpoint may regulate the metaphase-to-anaphase transition in the absence of spindle damage during C. elegans meiosis...
  5. pmc Protein phosphatase 5 is a negative regulator of separase function during cortical granule exocytosis in C. elegans
    Christopher T Richie
    Laboratory of Biochemistry and Genetics, NIDDK, NIH, Bethesda, MD 20892, USA
    J Cell Sci 124:2903-13. 2011
    ..The identification of PPH-5 as a suppressor of separase suggests that a new phospho-regulatory pathway plays an important role in regulating anaphase functions of separase...
  6. pmc Developmental defects observed in hypomorphic anaphase-promoting complex mutants are linked to cell cycle abnormalities
    Diane C Shakes
    Department of Biology, College of William and Mary, Williamsburg, Virginia 23187, USA
    Development 130:1605-20. 2003
    ....
  7. pmc Inactivation of the C. elegans lipin homolog leads to ER disorganization and to defects in the breakdown and reassembly of the nuclear envelope
    Andy Golden
    The Laboratory of Biochemistry and Genetics and National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 8 Center Drive, Bethesda, MD 20892, USA
    J Cell Sci 122:1970-8. 2009
    ..These results uncover cellular processes affected by lipin in metazoa, and suggest that lipid synthesis has a role in NE dynamics...
  8. pmc Functional redundancy of paralogs of an anaphase promoting complex/cyclosome subunit in Caenorhabditis elegans meiosis
    Kathryn K Stein
    Laboratory of Biochemistry and Genetics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Genetics 186:1285-93. 2010
    ..In sum, the two C. elegans APC5 paralogs have a redundant function during the meiotic divisions...
  9. ncbi request reprint Getting (chromosomes) loaded--a new role for timeless
    Andy Golden
    Laboratory of Biochemistry and Genetics, NIDDK, NIH, Bethesda, MD 20892, USA
    Dev Cell 5:7-9. 2003
    ..The phenotypes of tim-1 mutants suggest that cohesin subunits load onto chromosomes in a stepwise manner. Whether TIM-1 is also involved in circadian rhythms is discussed...
  10. doi request reprint Confocal imaging of the microtubule cytoskeleton in C. elegans embryos and germ cells
    KEVIN F O'CONNELL
    Laboratory of Biochemistry and Genetics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA
    Methods Mol Biol 1075:257-72. 2014
    ..elegans, a model organism that has been employed with great success to study the microtubule cytoskeleton and its roles in cell division and cell polarity. ..
  11. ncbi request reprint Chromosome segregation: Aurora B gets Tousled
    Christopher T Richie
    Laboratory of Biochemistry and Genetics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA
    Curr Biol 15:R379-82. 2005
    ....
  12. pmc Multiple subunits of the Caenorhabditis elegans anaphase-promoting complex are required for chromosome segregation during meiosis I
    Edward S Davis
    Laboratory of Biochemistry and Genetics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892 0840, USA
    Genetics 160:805-13. 2002
    ..Further, chromosome segregation during meiosis I requires APC/C functions in addition to the release of sister chromatid cohesion...
  13. pmc Hypothesis: Bifunctional mitochondrial proteins have centrosomal functions
    Akilah Moore
    Laboratory of Biochemistry and Genetics, National Institute of Diabetes, Digestive, and Kidney Diseases NIH, 8 Center Drive, Bethesda, MD 20892, USA
    Environ Mol Mutagen 50:637-48. 2009
    ..Throughout this discussion we attempt to demonstrate that a cell cannot live without mitochondria and study this issue from a nonenergetic perspective...
  14. ncbi request reprint Cortical granule exocytosis in C. elegans is regulated by cell cycle components including separase
    JOSHUA N BEMBENEK
    University of Wisconsin Madison, Laboratory of Molecular Biology, 1525 Linden Drive, Madison, WI 53706, USA
    Development 134:3837-48. 2007
    ..These observations lead us to speculate that SEP-1 has two separable yet coordinated functions: to regulate cortical granule exocytosis and to mediate chromosome separation...
  15. ncbi request reprint CDC-25.1 regulates germline proliferation in Caenorhabditis elegans
    Neville Ashcroft
    Genome Damage and Stability Centre, University of Sussex, Falmer, Brighton, United Kingdom
    Genesis 33:1-7. 2002
    ..Germline precursors divide slowly and produce abnormally sized daughter cells. Only three to four rounds of germ-cell division occur before they die during the L3 and L4 larval stages...
  16. ncbi request reprint The Caenorhabditis elegans par-5 gene encodes a 14-3-3 protein required for cellular asymmetry in the early embryo
    Diane G Morton
    Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853, USA
    Dev Biol 241:47-58. 2002
    ..Our analysis indicates that the par-5 14-3-3 gene plays a crucial role in the early events leading to polarization of the C. elegans zygote...