Adam B Glick

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint TGFbeta1, back to the future: revisiting its role as a transforming growth factor
    Adam B Glick
    Laboratory of Cellular Carcinogenesis and Tumor Promotion, The Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA
    Cancer Biol Ther 3:276-83. 2004
  2. ncbi request reprint Context-dependent regulation of cutaneous immunological responses by TGFbeta1 and its role in skin carcinogenesis
    Adam B Glick
    Department of Veterinary and Biomedical Sciences, Center for Molecular Toxicology and Carcinogenesis, Life Sciences Building, The Pennsylvania State University, University Park, PA 16801, USA
    Carcinogenesis 29:9-14. 2008
  3. doi request reprint The transcriptional regulatory function of p53 is essential for suppression of mouse skin carcinogenesis and can be dissociated from effects on TGF-beta-mediated growth regulation
    Roshini M Ponnamperuma
    Food and Drug Administration, Bethesda, MD 20892, USA
    J Pathol 219:263-74. 2009
  4. pmc Tumor suppressor and oncogene actions of TGFbeta1 occur early in skin carcinogenesis and are mediated by Smad3
    Dong Soon Bae
    Laboratory of Cancer Biology and Genetics, National Cancer Institute, Bethesda, MD, USA
    Mol Carcinog 48:441-53. 2009
  5. ncbi request reprint Tissue homeostasis and the control of the neoplastic phenotype in epithelial cancers
    Adam B Glick
    Laboratory of Cellular Carcinogenesis and Tumor Promotion, Center for Cancer Research, National Cancer Institute, 37 Convent Drive, MSC 4255, Building 37, Room 4068A1, Bethesda, MD 20892 4255, USA
    Semin Cancer Biol 15:75-83. 2005
  6. doi request reprint Cripto-1 alters keratinocyte differentiation via blockade of transforming growth factor-beta1 signaling: role in skin carcinogenesis
    Anjali Shukla
    Laboratory of Cancer Biology and Genetics, National Cancer Institute, Bethesda, Maryland, USA
    Mol Cancer Res 6:509-16. 2008
  7. ncbi request reprint Smad3 regulates senescence and malignant conversion in a mouse multistage skin carcinogenesis model
    Kinnimulki Vijayachandra
    Laboratory of Cellular Carcinogenesis and Tumor Promotion, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    Cancer Res 63:3447-52. 2003
  8. ncbi request reprint Involvement of Smad signaling in sphingosine 1-phosphate-mediated biological responses of keratinocytes
    Bettina Sauer
    Institute of Pharmacy, Pharmacology and Toxicology, Free University Berlin, Konigin Luise Strasse 2 4, D 14195 Berlin, Germany
    J Biol Chem 279:38471-9. 2004
  9. pmc An efficient and versatile system for acute and chronic modulation of renal tubular function in transgenic mice
    Milena Traykova-Brauch
    Department of Cellular and Molecular Pathology, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
    Nat Med 14:979-84. 2008

Collaborators

  • Tamador Elsir
  • Wendy C Weinberg
  • Dean Felsher
  • W Kriz
  • Anita B Roberts
  • David Kwiatkowski
  • Roshini M Ponnamperuma
  • Dong Soon Bae
  • Milena Traykova-Brauch
  • Anjali Shukla
  • Jessica Lee
  • Bettina Sauer
  • Kinnimulki Vijayachandra
  • Kathryn E King
  • Monica Nister
  • Geoffrey M Wahl
  • Nicholas Blazanin
  • Mathew Licata
  • Jurgen Horst
  • Tewfik Miloud
  • Andrew Ryscavage
  • Yan Ho
  • Magnus von Knebel Doeberitz
  • Xin Liu
  • Robert Koesters
  • Manja Bode
  • Hermann Josef Grone
  • Felix K Niggli
  • Kai Schonig
  • Anna Jauch
  • Oliver Greiner
  • Hermann Bujard
  • Henrik von Wenckstern
  • Makiko Fujii
  • Mario B Anzano
  • Monika Schäfer-Korting
  • Burkhard Kleuser
  • Rüdiger Vogler

Detail Information

Publications9

  1. ncbi request reprint TGFbeta1, back to the future: revisiting its role as a transforming growth factor
    Adam B Glick
    Laboratory of Cellular Carcinogenesis and Tumor Promotion, The Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA
    Cancer Biol Ther 3:276-83. 2004
    ..It is proposed that the switch from tumor suppressor to oncogene reflects genetic or epigenetic alterations in signaling pathways in tumor cells that alter the readout from the TGFbeta1 pathway...
  2. ncbi request reprint Context-dependent regulation of cutaneous immunological responses by TGFbeta1 and its role in skin carcinogenesis
    Adam B Glick
    Department of Veterinary and Biomedical Sciences, Center for Molecular Toxicology and Carcinogenesis, Life Sciences Building, The Pennsylvania State University, University Park, PA 16801, USA
    Carcinogenesis 29:9-14. 2008
    ....
  3. doi request reprint The transcriptional regulatory function of p53 is essential for suppression of mouse skin carcinogenesis and can be dissociated from effects on TGF-beta-mediated growth regulation
    Roshini M Ponnamperuma
    Food and Drug Administration, Bethesda, MD 20892, USA
    J Pathol 219:263-74. 2009
    ....
  4. pmc Tumor suppressor and oncogene actions of TGFbeta1 occur early in skin carcinogenesis and are mediated by Smad3
    Dong Soon Bae
    Laboratory of Cancer Biology and Genetics, National Cancer Institute, Bethesda, MD, USA
    Mol Carcinog 48:441-53. 2009
    ....
  5. ncbi request reprint Tissue homeostasis and the control of the neoplastic phenotype in epithelial cancers
    Adam B Glick
    Laboratory of Cellular Carcinogenesis and Tumor Promotion, Center for Cancer Research, National Cancer Institute, 37 Convent Drive, MSC 4255, Building 37, Room 4068A1, Bethesda, MD 20892 4255, USA
    Semin Cancer Biol 15:75-83. 2005
    ..Understanding these mechanisms will be important in primary cancer prevention and for counteracting recurrences in cancer survivors...
  6. doi request reprint Cripto-1 alters keratinocyte differentiation via blockade of transforming growth factor-beta1 signaling: role in skin carcinogenesis
    Anjali Shukla
    Laboratory of Cancer Biology and Genetics, National Cancer Institute, Bethesda, Maryland, USA
    Mol Cancer Res 6:509-16. 2008
    ..We suggest that inhibition of TGF-beta1 by Cripto-1 may play an important role in altering the differentiation state of keratinocytes and promoting outgrowth of squamous tumors in the mouse epidermis...
  7. ncbi request reprint Smad3 regulates senescence and malignant conversion in a mouse multistage skin carcinogenesis model
    Kinnimulki Vijayachandra
    Laboratory of Cellular Carcinogenesis and Tumor Promotion, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    Cancer Res 63:3447-52. 2003
    ..These results link Smad3-mediated regulation of growth control genes to senescence in vitro and tumor suppression in vivo...
  8. ncbi request reprint Involvement of Smad signaling in sphingosine 1-phosphate-mediated biological responses of keratinocytes
    Bettina Sauer
    Institute of Pharmacy, Pharmacology and Toxicology, Free University Berlin, Konigin Luise Strasse 2 4, D 14195 Berlin, Germany
    J Biol Chem 279:38471-9. 2004
    ....
  9. pmc An efficient and versatile system for acute and chronic modulation of renal tubular function in transgenic mice
    Milena Traykova-Brauch
    Department of Cellular and Molecular Pathology, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
    Nat Med 14:979-84. 2008
    ..These experiments establish Pax8-rtTA mice as a powerful tool for modeling renal diseases in transgenic mice...