Research Topics
Species | Gretchen L GierachSummaryAffiliation: National Institutes of Health Country: USA Publications
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Detail Information
Publications
Relationship between mammographic density and breast cancer death in the Breast Cancer Surveillance ConsortiumGretchen L Gierach
Hormonal and Reproductive Epidemiology Branch, National Cancer Institute, National Institutes of Health, Rockville, MD, USA
J Natl Cancer Inst 104:1218-27. 2012..Women with elevated mammographic density have an increased risk of developing breast cancer. However, among women diagnosed with breast cancer, it is unclear whether higher density portends reduced survival, independent of other factors...
Coffee intake and breast cancer risk in the NIH-AARP diet and health study cohortGretchen L Gierach
Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Blvd, Suite 550, Rockville, MD, USA
Int J Cancer 131:452-60. 2012..Null findings persisted for risk of both HR-positive and -negative breast cancers. These findings from a large prospective cohort do not support a role of coffee intake in breast carcinogenesis...- Mammographic density does not differ between unaffected BRCA1/2 mutation carriers and women at low-to-average risk of breast cancerGretchen L Gierach
Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, Office of Preventive Oncology, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
Breast Cancer Res Treat 123:245-55. 2010..Taking these factors into account did not significantly alter the results of the age/body mass index-adjusted analysis. Our results do not provide support for an independent effect of BRCA1/2 mutation status on mammographic density... - Nonsteroidal anti-inflammatory drugs and breast cancer risk in the National Institutes of Health-AARP Diet and Health StudyGretchen L Gierach
Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, 6120 Executive Blvd, Suite 550, Rockville, MD 20852 7234, USA
Breast Cancer Res 10:R38. 2008..Epidemiologic evidence for a protective role of NSAIDs in breast cancer, however, is equivocal... - Physical activity, sedentary behavior, and endometrial cancer risk in the NIH-AARP Diet and Health StudyGretchen L Gierach
Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD 20852 7234, USA
Int J Cancer 124:2139-47. 2009..02). Associations with vigorous activities, which may interact with body mass index, suggest directions for future research to clarify underlying biologic mechanisms, including those relating to hormonal alterations... - Prediagnosis body mass index, physical activity, and mortality in endometrial cancer patientsHannah Arem
MHS, 6120 Executive Blvd, EPS 3029, Rockville, MD 20852, USA
J Natl Cancer Inst 105:342-9. 2013..Intervention studies of the effect of these modifiable lifestyle factors on mortality are needed... - Intensity and timing of physical activity in relation to postmenopausal breast cancer risk: the prospective NIH-AARP diet and health studyTricia M Peters
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, 6120 Executive Blvd, Bethesda, MD, USA
BMC Cancer 9:349. 2009..Despite strong evidence of an inverse association of physical activity with postmenopausal breast cancer risk, whether a certain intensity or time of life of physical activity is most effective for lowering breast cancer risk is not known... - Physical activity and postmenopausal breast cancer risk in the NIH-AARP diet and health studyTricia M Peters
Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, 6120 Executive Boulevard, MSC 7232, Bethesda, MD 20892, USA
Cancer Epidemiol Biomarkers Prev 18:289-96. 2009..Although physical activity has been associated with reduced breast cancer risk, whether this association varies across breast cancer subtypes or is modified by reproductive and lifestyle factors is unclear... - Endometrial cancer risk factors by 2 main histologic subtypes: the NIH-AARP Diet and Health StudyHannah P Yang
Hormonal and Reproductive Epidemiology Branch, National Cancer Institute, NIH, Department of Human Services, Bethesda, USA
Am J Epidemiol 177:142-51. 2013..Because of the limited number of Type II cancers, additional evaluation of risk factors will benefit from consortial efforts... - Body mass index and risk of lung cancer among never, former, and current smokersLlewellyn Smith
Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD 20852 7234, USA
J Natl Cancer Inst 104:778-89. 2012..These studies are difficult to interpret because of potential confounding by cigarette smoking, a major risk factor for lung cancer that is associated with lower BMI... - Unopposed estrogen and estrogen plus progestin menopausal hormone therapy and lung cancer risk in the NIH-AARP Diet and Health Study CohortLouise A Brinton
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD 20852, USA
Cancer Causes Control 23:487-96. 2012..Previous studies have reported that lung cancer risk may be decreased, increased, or unaffected by prior use of menopausal hormone therapy (MHT)... - Menopausal hormone therapy and breast cancer risk in the NIH-AARP Diet and Health Study CohortLouise A Brinton
Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, USA
Cancer Epidemiol Biomarkers Prev 17:3150-60. 2008..Results from the Women's Health Initiative trial raise new questions regarding the effects of estrogen therapy (ET) and estrogen plus progestin therapy (EPT) on breast cancer risk... - Alcohol and endometrial cancer risk in the NIH-AARP diet and health studyHannah P Yang
Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20852, USA
Int J Cancer 128:2953-61. 2011..Our results do not support that alcohol is a strong contributor to endometrial cancer risk, but slight risk increases may prevail among some users or for selected tumor characteristics... - Nonsteroidal anti-inflammatory drug use and endometrial cancer risk in the NIH-AARP Diet and Health StudyKim N Danforth
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health DHHS, 6120 Executive Boulevard, Rockville, MD 20852, USA
Cancer Prev Res (Phila) 2:466-72. 2009..Overall, our data do not support an association between aspirin or NA-NSAID use and endometrial cancer risk... - Reproductive and hormonal factors and lung cancer risk in the NIH-AARP Diet and Health Study cohortLouise A Brinton
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Rockville, MD 20852, USA
Cancer Epidemiol Biomarkers Prev 20:900-11. 2011..Inconsistent findings about hormonal factors on risk may reflect incomplete control for confounding, misclassification of exposures, or insufficient attention to variation by histology... - Prospective evaluation of risk factors for male breast cancerLouise A Brinton
Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20852 7234, USA
J Natl Cancer Inst 100:1477-81. 2008..Differences in risk factors may reflect unique mechanisms associated with androgens and their ratio to bioavailable estrogens... - Estrogen metabolism and mammographic density in postmenopausal women: a cross-sectional studyBarbara J Fuhrman
Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD 20892, USA
Cancer Epidemiol Biomarkers Prev 21:1582-91. 2012..We investigated the cross-sectional associations of urinary estrogens, and their 2-, 4-, and 16-hydroxylated metabolites with MD... - Epithelial ovarian cancer and exposure to dietary nitrate and nitrite in the NIH-AARP Diet and Health StudyBriseis Aschebrook-Kilfoy
Occupational and Environmental Epidemiology Branch, DCEG, NCI, NIH, Rockville, Maryland 20852, USA
Eur J Cancer Prev 21:65-72. 2012..There were no clear differences in risk by histologic subtype of ovarian cancer. Our findings suggest that a role of dietary nitrate and nitrite in ovarian cancer risk should be followed in other large cohort studies... - Etiologic factors for male breast cancer in the U.S. Veterans Affairs medical care system databaseLouise A Brinton
Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Room 5018, Rockville, MD 20852, USA
Breast Cancer Res Treat 119:185-92. 2010..21-8.03), obesity (1.91, 1.50-2.44), and orchitis/epididymitis (1.80, 1.08-3.01). These results support previous speculations that male breast cancer is influenced not only by tissue at risk, but also by hormonal and inflammatory factors... - Accelerometer-based measures of active and sedentary behavior in relation to breast cancer riskCher M Dallal
Cancer Prevention Fellowship Program, Center for Cancer Training, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
Breast Cancer Res Treat 134:1279-90. 2012..Our findings support an inverse association between accelerometer-based measures of moderate-to-vigorous physical activity and breast cancer while also suggesting potential increases in risk with sedentary time... - Epidemiology of triple negative breast cancersGretchen L Gierach
Hormonal and Reproductive Epidemiology Branch, DHHS NIH NCI Division of Cancer Epidemiology and Genetics, Bethesda, MD 20892 7244, USA
Breast Dis 32:5-24. 2010..Information sources for this review included the National Cancer Institute's Surveillance, Epidemiology, and End Results 13 Registries Public-Use Database [5], CANCERLIT, Index Medicus, and PubMed... - Expression of TGF-beta signaling factors in invasive breast cancers: relationships with age at diagnosis and tumor characteristicsJonine D Figueroa
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
Breast Cancer Res Treat 121:727-35. 2010..These results warrant analysis in studies of clinical outcomes accounting for age, ER status and treatment... 
Recreational physical activity and mammographic breast density characteristicsKatherine W Reeves
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Suite 510, 3520 Fifth Avenue, Pittsburgh, PA 15213, USA
Cancer Epidemiol Biomarkers Prev 16:934-42. 2007..These results suggest that the mechanism by which physical activity reduces breast cancer risk may not involve breast density...- Nonsteroidal anti-inflammatory drug use and serum total estradiol in postmenopausal womenAlana G Hudson
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Cancer Epidemiol Biomarkers Prev 17:680-7. 2008..These cross-sectional findings suggest that NSAID use may be associated with lower circulating estradiol levels, potentially representing one mechanism through which NSAIDs exert protective effects on breast cancer... - Hostility scores are associated with increased risk of cardiovascular events in women undergoing coronary angiography: a report from the NHLBI-Sponsored WISE StudyMarian B Olson
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA
Psychosom Med 67:546-52. 2005..To evaluate hostility-related personality traits assessed by the Cook Medley Hostility Inventory and to relate these to the occurrence of adverse cardiac events in women with suspected myocardial ischemia...