Jay N Giedd

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Review: magnetic resonance imaging of male/female differences in human adolescent brain anatomy
    Jay N Giedd
    Child Psychiatry Branch, Brain Imaging Unit, National Institute of Mental Health, National Institutes of Health, 10 Center Drive, MSC 1367, Building 10, Room 4 C110, Bethesda, MD, 20892, USA
    Biol Sex Differ 3:19. 2012
  2. doi request reprint The teen brain: insights from neuroimaging
    Jay N Giedd
    Brain Imaging Unit, Child Psychiatry Branch, National Institute of Mental Health, Bethesda, Maryland 20892, USA
    J Adolesc Health 42:335-43. 2008
  3. pmc Anatomic magnetic resonance imaging of the developing child and adolescent brain and effects of genetic variation
    Jay N Giedd
    Child Psychiatry Branch, National Institutes of Mental Health, Bethesda, MD, USA
    Neuropsychol Rev 20:349-61. 2010
  4. ncbi request reprint Structural magnetic resonance imaging of the adolescent brain
    Jay N Giedd
    National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Room 4C110, 10 Center Dr MSC 1367, Bethesda, MD 20892 1367, USA
    Ann N Y Acad Sci 1021:77-85. 2004
  5. ncbi request reprint Puberty-related influences on brain development
    Jay N Giedd
    Child Psychiatry Branch, National Institute of Mental Health, Building 10, Room 4C110, 10 Center Drive, MSC 1367, Bethesda, MD 20892, United States
    Mol Cell Endocrinol 254:154-62. 2006
  6. ncbi request reprint Structural brain magnetic resonance imaging of pediatric twins
    Jay N Giedd
    Child Psychiatry Branch, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
    Hum Brain Mapp 28:474-81. 2007
  7. pmc Structural MRI of pediatric brain development: what have we learned and where are we going?
    Jay N Giedd
    Child Psychiatry Branch NIMH, Bethesda, MD 20892, USA
    Neuron 67:728-34. 2010
  8. ncbi request reprint XXY (Klinefelter syndrome): a pediatric quantitative brain magnetic resonance imaging case-control study
    Jay N Giedd
    Child Psychiatry Branch NIMH, National Institutes of Health, Building 10, Room 4C110, 10 Center Dr, MSC 1367, Bethesda, MD 20892, USA
    Pediatrics 119:e232-40. 2007
  9. ncbi request reprint Dynamic mapping of hippocampal development in childhood onset schizophrenia
    Tom F Nugent
    Child Psychiatry Branch, NIMH, Bethesda, MD 20892, USA
    Schizophr Res 90:62-70. 2007
  10. pmc Sexual dimorphism of brain developmental trajectories during childhood and adolescence
    Rhoshel K Lenroot
    Child Psychiatry Branch of the National Institute of Mental Health, NIMH CHP 10 Center Drive, Bethesda, MD 20814 9692, USA
    Neuroimage 36:1065-73. 2007

Detail Information

Publications72

  1. pmc Review: magnetic resonance imaging of male/female differences in human adolescent brain anatomy
    Jay N Giedd
    Child Psychiatry Branch, Brain Imaging Unit, National Institute of Mental Health, National Institutes of Health, 10 Center Drive, MSC 1367, Building 10, Room 4 C110, Bethesda, MD, 20892, USA
    Biol Sex Differ 3:19. 2012
    ..White matter volumes increase throughout childhood and adolescence in both sexes but more rapidly in adolescent males resulting in an expanding magnitude of sex differences from childhood to adulthood...
  2. doi request reprint The teen brain: insights from neuroimaging
    Jay N Giedd
    Brain Imaging Unit, Child Psychiatry Branch, National Institute of Mental Health, Bethesda, Maryland 20892, USA
    J Adolesc Health 42:335-43. 2008
    ....
  3. pmc Anatomic magnetic resonance imaging of the developing child and adolescent brain and effects of genetic variation
    Jay N Giedd
    Child Psychiatry Branch, National Institutes of Mental Health, Bethesda, MD, USA
    Neuropsychol Rev 20:349-61. 2010
    ....
  4. ncbi request reprint Structural magnetic resonance imaging of the adolescent brain
    Jay N Giedd
    National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Room 4C110, 10 Center Dr MSC 1367, Bethesda, MD 20892 1367, USA
    Ann N Y Acad Sci 1021:77-85. 2004
    ..The details of the relationships between anatomical changes and behavioral changes, and the forces that influence brain development, have not been well established and remain a prominent goal of ongoing investigations...
  5. ncbi request reprint Puberty-related influences on brain development
    Jay N Giedd
    Child Psychiatry Branch, National Institute of Mental Health, Building 10, Room 4C110, 10 Center Drive, MSC 1367, Bethesda, MD 20892, United States
    Mol Cell Endocrinol 254:154-62. 2006
    ..Subjects with XXY have gray matter reductions in the insula, temporal gyri, amygdala, hippocampus, and cingulate-areas consistent with the language-based learning difficulties common in this group...
  6. ncbi request reprint Structural brain magnetic resonance imaging of pediatric twins
    Jay N Giedd
    Child Psychiatry Branch, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA
    Hum Brain Mapp 28:474-81. 2007
    ..Understanding of influences on trajectories of brain development may shed light on the emergence of psychopathology during childhood and adolescence and ultimately may guide therapeutic interventions...
  7. pmc Structural MRI of pediatric brain development: what have we learned and where are we going?
    Jay N Giedd
    Child Psychiatry Branch NIMH, Bethesda, MD 20892, USA
    Neuron 67:728-34. 2010
    ..In this review we summarize general contributions of structural MRI to our understanding of neurodevelopment in health and illness...
  8. ncbi request reprint XXY (Klinefelter syndrome): a pediatric quantitative brain magnetic resonance imaging case-control study
    Jay N Giedd
    Child Psychiatry Branch NIMH, National Institutes of Health, Building 10, Room 4C110, 10 Center Dr, MSC 1367, Bethesda, MD 20892, USA
    Pediatrics 119:e232-40. 2007
    ..The objective of this study was to examine possible neuroanatomical substrates of these cognitive and behavioral features during childhood and adolescence...
  9. ncbi request reprint Dynamic mapping of hippocampal development in childhood onset schizophrenia
    Tom F Nugent
    Child Psychiatry Branch, NIMH, Bethesda, MD 20892, USA
    Schizophr Res 90:62-70. 2007
    ....
  10. pmc Sexual dimorphism of brain developmental trajectories during childhood and adolescence
    Rhoshel K Lenroot
    Child Psychiatry Branch of the National Institute of Mental Health, NIMH CHP 10 Center Drive, Bethesda, MD 20814 9692, USA
    Neuroimage 36:1065-73. 2007
    ..These sexually dimorphic trajectories confirm the importance of longitudinal data in studies of brain development and underline the need to consider sex matching in studies of brain development...
  11. ncbi request reprint Differences in genetic and environmental influences on the human cerebral cortex associated with development during childhood and adolescence
    Rhoshel K Lenroot
    Child Psychiatry Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892 9692, USA
    Hum Brain Mapp 30:163-74. 2009
    ..These results suggest that both the specific cortical region and the age of the population should be taken into account when using cortical thickness as an intermediate phenotype to link genes, environment, and behavior...
  12. ncbi request reprint Delayed white matter growth trajectory in young nonpsychotic siblings of patients with childhood-onset schizophrenia
    Nitin Gogtay
    Child Psychiatry Branch, National Institute of Mental Health, Bethesda, Maryland, USA
    Arch Gen Psychiatry 69:875-84. 2012
    ..As reported before for gray matter, WM growth may also be an age-specific endophenotype that shows compensatory normalization with age...
  13. pmc Catechol-o-methyl transferase (COMT) val158met polymorphism and adolescent cortical development in patients with childhood-onset schizophrenia, their non-psychotic siblings, and healthy controls
    Armin Raznahan
    Child Psychiatry Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MA 20892, USA
    Neuroimage 57:1517-23. 2011
    ..These findings suggest that cortical abnormalities in pedigrees affected by schizophrenia may be contributed to by a disruption of dopaminergic infleunces on cortical maturation...
  14. ncbi request reprint Progressive brain volume loss during adolescence in childhood-onset schizophrenia
    Alexandra L Sporn
    Child Psychiatry Branch, NIMH, Bldg 10, Rm 3N202, Bethesda, MD 20892, USA
    Am J Psychiatry 160:2181-9. 2003
    ..This study examined the rate of loss in cortical gray matter volume in relation to age and clinical status in adolescent patients over a follow-up period of 2-6 years...
  15. pmc Allelic variation within the putative autism spectrum disorder risk gene homeobox A1 and cerebellar maturation in typically developing children and adolescents
    Armin Raznahan
    Child Psychiatry Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Autism Res 5:93-100. 2012
    ..002). Our results suggest that common genetic variation within this putative ASD risk gene has the capacity to modify the development of cerebellar systems implicated in ASD neurobiology...
  16. pmc Distinct cortical correlates of autistic versus antisocial traits in a longitudinal sample of typically developing youth
    Gregory L Wallace
    Laboratory of Brain and Cognition, National Institute of Mental Health, NIH, Bethesda, Maryland 20892 1366, USA
    J Neurosci 32:4856-60. 2012
    ..These results support the dimensional view of psychopathology and provide neural signatures that can serve as informative endophenotypes for future genetic studies...
  17. ncbi request reprint Comparison of progressive cortical gray matter loss in childhood-onset schizophrenia with that in childhood-onset atypical psychoses
    Nitin Gogtay
    Child Psychiatry Branch, National Institute of Mental Health NIH, Building 10, Room 3N202, 10 Center Drive, MSC 1600, Bethesda, MD 20892 1600, USA
    Arch Gen Psychiatry 61:17-22. 2004
    ..We hypothesized that cortical GM loss would occur in patients with COS but not in adolescents with atypical psychoses...
  18. ncbi request reprint Polymorphisms of the dopamine D4 receptor, clinical outcome, and cortical structure in attention-deficit/hyperactivity disorder
    Philip Shaw
    Child Psychiatry Branch, Room 3N202, Bldg 10, Center Drive, National Institute of Mental Health, Bethesda, MD 20892, USA
    Arch Gen Psychiatry 64:921-31. 2007
    ..Attention-deficit/hyperactivity disorder (ADHD) is one of the most heritable neuropsychiatric disorders, and a polymorphism within the dopamine D4 receptor (DRD4) gene has been frequently implicated in its pathogenesis...
  19. pmc How does your cortex grow?
    Armin Raznahan
    Child Psychiatry Branch, National Institute of Mental Health, Bethesda, Maryland 20892, USA
    J Neurosci 31:7174-7. 2011
    ..Knowing of these developmental dissociations, and further specifying their timing and sex-biases, provides potent new research targets for basic and clinical neuroscience...
  20. doi request reprint Patterns of coordinated anatomical change in human cortical development: a longitudinal neuroimaging study of maturational coupling
    Armin Raznahan
    Child Psychiatry Branch, National Institute of Health, National Institutes of Mental Health, Bethesda, MD 20892, USA
    Neuron 72:873-84. 2011
    ....
  21. ncbi request reprint A pediatric twin study of brain morphometry
    Gregory L Wallace
    Child Psychiatry Branch, National Institute of Mental Health, Bethesda, MD, USA
    J Child Psychol Psychiatry 47:987-93. 2006
    ..Studies of monozygotic and dyzygotic twins during this developmental period allow exploration of genetic and non-genetic influences on these developmental trajectories...
  22. ncbi request reprint Dynamic mapping of cortical development before and after the onset of pediatric bipolar illness
    Nitin Gogtay
    Child Psychiatry Branch, NIMH, Bethesda, MD 20892, USA
    J Child Psychol Psychiatry 48:852-62. 2007
    ..We report the first prospective study of cortical brain development in pediatric bipolar illness for 9 male children, visualized before and after illness onset...
  23. doi request reprint Neurodevelopmental trajectories of the human cerebral cortex
    Philip Shaw
    Child Psychiatry Branch, National Institute of Mental Health, Bethesda, Maryland 20892, USA
    J Neurosci 28:3586-94. 2008
    ....
  24. pmc Autism risk gene MET variation and cortical thickness in typically developing children and adolescents
    Alexis Hedrick
    Child Psychiatry Branch, National Institute of Mental Health, Bethesda, MD 20814, USA
    Autism Res 5:434-9. 2012
    ..Our results suggest that genetic differences in the MET gene may influence the development of cortical systems implicated in the neurobiology of ASD...
  25. pmc Longitudinally mapping the influence of sex and androgen signaling on the dynamics of human cortical maturation in adolescence
    Armin Raznahan
    Child Psychiatry Branch, National Institute of Mental Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 107:16988-93. 2010
    ....
  26. pmc Trajectories of anatomic brain development as a phenotype
    Jay N Giedd
    Brain Imaging Unit, Child Psychiatry Branch NIMH, 10 Center Drive, MSC 1367 Bethesda, MD 20892, USA
    Novartis Found Symp 289:101-12; discussion 112-8, 193-5. 2008
    ....
  27. ncbi request reprint Cortical morphology in children and adolescents with different apolipoprotein E gene polymorphisms: an observational study
    Philip Shaw
    Child Psychiatry Branch, National Institute of Mental Health, Bethesda, MD, USA
    Lancet Neurol 6:494-500. 2007
    ....
  28. ncbi request reprint Dynamic mapping of normal human hippocampal development
    Nitin Gogtay
    Child Psychiatry Branch, NIMH, Bethesda, Maryland 20892, USA
    Hippocampus 16:664-72. 2006
    ..These distinct developmental trajectories of hippocampal subregions may parallel differences in their functional development...
  29. ncbi request reprint Corpus callosum development in childhood-onset schizophrenia
    Audrey Keller
    Child Psychiatry Branch, National Institute of Mental Health, Building 10, Room 3N 202, 10 Center Drive MSC 1600, Bethesda, MD 20892 1600, USA
    Schizophr Res 62:105-14. 2003
    ..Corpus callosal area was examined for COS at initial scan and prospectively through adolescence, and related to other developmental abnormalities for this group...
  30. pmc A bivariate twin study of regional brain volumes and verbal and nonverbal intellectual skills during childhood and adolescence
    Gregory L Wallace
    Child Psychiatry Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, 20892 1600, USA
    Behav Genet 40:125-34. 2010
    ..These results suggest that distinct mechanisms contribute to the small phenotypic relationships between brain volumes and verbal versus nonverbal intelligence...
  31. ncbi request reprint Effects of hormones and sex chromosomes on stress-influenced regions of the developing pediatric brain
    A Blythe Rose
    National Institute of Mental Health, National Institutes of Health, Bldg 10, Rm 4C110, 10 Center Drive, Bethesda, MD 20892, USA
    Ann N Y Acad Sci 1032:231-3. 2004
    ..Future studies that examine longitudinal data and/or other diagnostic groups, however, may help to better elucidate specific hormone and sex chromosome effects upon stress-related structures in the brain...
  32. ncbi request reprint Compared to what? Early brain overgrowth in autism and the perils of population norms
    Armin Raznahan
    Child Psychiatry Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland Electronic address
    Biol Psychiatry 74:563-75. 2013
    ....
  33. pmc Three-dimensional brain growth abnormalities in childhood-onset schizophrenia visualized by using tensor-based morphometry
    Nitin Gogtay
    Child Psychiatry Branch, National Institute of Mental Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 105:15979-84. 2008
    ..Growth rates were correlated with functional prognosis and were visualized as detailed 3D maps. Finally, these findings also confirm that the progressive GM deficits seen in schizophrenia are not the result of WM overgrowth...
  34. pmc The changing impact of genes and environment on brain development during childhood and adolescence: initial findings from a neuroimaging study of pediatric twins
    Rhoshel K Lenroot
    National Institutes of Mental Health, Bethesda, MD 20892 1600, USA
    Dev Psychopathol 20:1161-75. 2008
    ..Areas associated with more complex reasoning abilities become increasingly heritable with maturation. The potential mechanisms by which gene-environment interactions may affect heritability values during development is discussed...
  35. pmc Longitudinal four-dimensional mapping of subcortical anatomy in human development
    Armin Raznahan
    Child Psychiatry Branch, National Institute of Mental Health, Bethesda, MD 20892
    Proc Natl Acad Sci U S A 111:1592-7. 2014
    ....
  36. pmc Increased gyrification, but comparable surface area in adolescents with autism spectrum disorders
    Gregory L Wallace
    Laboratory of Brain and Cognition National Institute of Mental Health, National Institute of Mental Health, Bethesda, MD 20892 1367, USA
    Brain 136:1956-67. 2013
    ....
  37. pmc Dosage effects of X and Y chromosomes on language and social functioning in children with supernumerary sex chromosome aneuploidies: implications for idiopathic language impairment and autism spectrum disorders
    Nancy Raitano Lee
    Child Psychiatry Branch, National Institute of Mental Health, NIH, Bethesda, MD 20892, USA
    J Child Psychol Psychiatry 53:1072-81. 2012
    ..The current research sought to fill this gap in the literature and to examine dosage effects of X and Y chromosomes on language and social functioning...
  38. pmc Cerebellum development during childhood and adolescence: a longitudinal morphometric MRI study
    Henning Tiemeier
    Child Psychiatry Branch, National Institute of Mental Health NIH, Bethesda, MD 20892, USA
    Neuroimage 49:63-70. 2010
    ....
  39. pmc Age-related temporal and parietal cortical thinning in autism spectrum disorders
    Gregory L Wallace
    Laboratory of Brain and Cognition, National Institute of Mental Health, Bethesda, MD 20892 1366, USA
    Brain 133:3745-54. 2010
    ..e. greater thinning) may be characteristic of these disorders...
  40. ncbi request reprint Children experience cognitive decline despite reversal of brain atrophy one year after resolution of Cushing syndrome
    Deborah P Merke
    Pediatric and Reproductive Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892 1932, USA
    J Clin Endocrinol Metab 90:2531-6. 2005
    ..Despite rapid reversibility of cerebral atrophy, children experience a significant decline in cognitive function 1 yr after correction of hypercortisolism...
  41. ncbi request reprint Anatomical coupling among distributed cortical regions in youth varies as a function of individual differences in vocabulary abilities
    Nancy Raitano Lee
    Child Psychiatry Branch, National Institute of Mental Health, NIH, Bethesda, Maryland
    Hum Brain Mapp 35:1885-95. 2014
    ....
  42. pmc Dynamic mapping of human cortical development during childhood through early adulthood
    Nitin Gogtay
    Child Psychiatry Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 101:8174-9. 2004
    ..Direct comparison with normal cortical development may help understanding of some neurodevelopmental disorders such as childhood-onset schizophrenia or autism...
  43. ncbi request reprint Structural brain MRI abnormalities in healthy siblings of patients with childhood-onset schizophrenia
    Nitin Gogtay
    Child Psychiatry Branch, National Institute of Mental Health, NationalInstitutes of Health, Bethesda, MD 20892 1600, USA
    Am J Psychiatry 160:569-71. 2003
    ....
  44. pmc Executive function in young males with Klinefelter (XXY) syndrome with and without comorbid attention-deficit/hyperactivity disorder
    Nancy Raitano Lee
    Child Psychiatry Branch, National Institute of Mental Health, NIH, Bethesda, Maryland
    J Int Neuropsychol Soc 17:522-30. 2011
    ..Overall, the XXY group performed less well than both control groups, but performance did not differ significantly as a function of task. ADHD comorbidity in males with XXY was related to poorer EF skills...
  45. pmc Quantitative morphology of the corpus callosum in obsessive-compulsive disorder
    Katherine C Lopez
    Child Psychiatry Branch, National Institute of Mental Health, National Institutes of Health, Building 10, Room 4C110, 10 Center Drive, MSC 1367, Bethesda, MD, USA
    Psychiatry Res 212:1-6. 2013
    ..These findings implicate medio-frontal regions of the cortex in the pathophysiology of OCD...
  46. pmc A magnetization transfer imaging study of corpus callosum myelination in young children with autism
    Marta Gozzi
    Pediatrics and Developmental Neuroscience Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892 1255, USA
    Biol Psychiatry 72:215-20. 2012
    ..Here, we used magnetization transfer imaging to provide insight into the myelination of the corpus callosum in children with autism...
  47. pmc Prenatal growth in humans and postnatal brain maturation into late adolescence
    Armin Raznahan
    Child Psychiatry Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 109:11366-71. 2012
    ..By mapping the sensitivity of postnatal human brain development to prenatal influences, our findings underline the potency of in utero life in shaping postnatal outcomes of neuroscientific and public health importance...
  48. ncbi request reprint Anatomic brain abnormalities in monozygotic twins discordant for attention deficit hyperactivity disorder
    F Xavier Castellanos
    Child Psychiatry Branch, National Institute of Mental Health NIH, Bethesda, MD, USA
    Am J Psychiatry 160:1693-6. 2003
    ..To examine brain-behavior relationships in attention deficit hyperactivity disorder (ADHD), the authors obtained magnetic resonance imaging (MRI) scans of monozygotic twins discordant for ADHD...
  49. ncbi request reprint Children with classic congenital adrenal hyperplasia have decreased amygdala volume: potential prenatal and postnatal hormonal effects
    Deborah P Merke
    Pediatric and Reproductive Endocrinology Branch, National Institute of Child Health and Human Development, The Warren Grant Magnuson Clinical Center, National Institutes of Health, Bethesda, Maryland 20892 1932, USA
    J Clin Endocrinol Metab 88:1760-5. 2003
    ....
  50. pmc Imaging structural co-variance between human brain regions
    Aaron Alexander-Bloch
    Child Psychiatry Branch, National Institute of Mental Health, Bethesda, Maryland 20892, USA
    Nat Rev Neurosci 14:322-36. 2013
    ..This Review discusses the state of current research into brain structural co-variance, its underlying mechanisms and its potential value in the understanding of various neurological and psychiatric conditions...
  51. ncbi request reprint Progressive loss of cerebellar volume in childhood-onset schizophrenia
    Audrey Keller
    Child Psychiatry Branch, National Institute of Mental Health, Bldg 10, Rm 3N 202, Bethesda, MD 20892 1600, USA
    Am J Psychiatry 160:128-33. 2003
    ....
  52. ncbi request reprint Brain development in children and adolescents: insights from anatomical magnetic resonance imaging
    Rhoshel K Lenroot
    Child Psychiatry Branch, National Institute of Mental Health, Building 10, Room 4C110, 10 Center Drive, Bethesda, MD 20854, USA
    Neurosci Biobehav Rev 30:718-29. 2006
    ..Studies are ongoing to explore the influences of genetic and environmental factors on developmental trajectories...
  53. pmc A case study of a multiply talented savant with an autism spectrum disorder: neuropsychological functioning and brain morphometry
    Gregory L Wallace
    Institute of Psychiatry, Social, Genetic, and Developmental Psychiatry Centre, King s College, University of London, London WC2R 2LS, UK
    Philos Trans R Soc Lond B Biol Sci 364:1425-32. 2009
    ..g. calendars, art, music) that capitalize upon strengths often associated with ASD, such as detail-focused processing, are probably further enhanced through over-learning and massive exposure, and reflected in atypical brain structure...
  54. pmc Cortical anatomy in human X monosomy
    Armin Raznahan
    Department of Child Psychiatry, Institute of Psychiatry, King s College London, UK
    Neuroimage 49:2915-23. 2010
    ..g. cortical folding) and CT (e.g. dendritic arborization/pruning). CT disruptions are maximal within and between cortical regions previously implicated in the TS cognitive phenotype...
  55. ncbi request reprint Prevalence of and risk factors for depressive symptoms among young adolescents
    Gitanjali Saluja
    National Institute of Child Health and Human Development, Rockville, MD 20892 7510, USA
    Arch Pediatr Adolesc Med 158:760-5. 2004
    ..To determine the prevalence, risk factors, and risk behaviors associated with depressive symptoms in a nationally representative, cross-sectional sample of young adolescents...
  56. ncbi request reprint High resolution whole brain imaging of anatomical variation in XO, XX, and XY mice
    Armin Raznahan
    Child Psychiatry Branch, National Institute of Mental Health, Bethesda, MD, USA Electronic address
    Neuroimage 83:962-8. 2013
    ..Integration of these data with existing genomic knowledge generates a set of novel, testable hypotheses regarding candidate mechanisms for each observed pattern of anatomical variation across XO, XX and XY groups...
  57. ncbi request reprint Developmental trajectories of brain volume abnormalities in children and adolescents with attention-deficit/hyperactivity disorder
    F Xavier Castellanos
    Child Psychiatry Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA
    JAMA 288:1740-8. 2002
    ..Various anatomic brain abnormalities have been reported for attention-deficit/hyperactivity disorder (ADHD), with varying methods, small samples, cross-sectional designs, and without accounting for stimulant drug exposure...
  58. ncbi request reprint The anatomy of mentalization: a view from developmental neuroimaging
    Jay N Giedd
    Brain Imaging Unit, Child Psychiatry Branch, National Institute of Mental Health, National Institutes of Health, U S Department of Health and Human Services, Rockville, Maryland, USA
    Bull Menninger Clin 67:132-42. 2003
    ....
  59. pmc The digital revolution and adolescent brain evolution
    Jay N Giedd
    Brain Imaging Section, Child Psychiatry Branch, National Institute of Mental Health, Bethesda, Maryland, USA
    J Adolesc Health 51:101-5. 2012
    ..The consequences of the brain's adaptation to the demands and opportunities of the digital age have enormous implications for adolescent health professionals...
  60. ncbi request reprint Motion artifact in magnetic resonance imaging: implications for automated analysis
    Jonathan D Blumenthal
    Child Psychiatry Branch, NIMH, NIH, Bethesda, Maryland, 20892 1367, USA
    Neuroimage 16:89-92. 2002
    ..Greater motion artifact was associated with smaller gray matter volumes. Severity of motion artifact is an important, but often overlooked, consideration in the interpretation of automated MRI measures...
  61. pmc Effects of sex chromosome aneuploidies on brain development: evidence from neuroimaging studies
    Rhoshel K Lenroot
    Child Psychiatry Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA
    Dev Disabil Res Rev 15:318-27. 2009
    ..The limited data regarding effects of having two Y chromosomes (47,XYY) do not find significant differences in brain volume, although there are some reports of increased head size...
  62. ncbi request reprint Dynamically spreading frontal and cingulate deficits mapped in adolescents with schizophrenia
    Christine N Vidal
    Laboratory of Neuro Imaging, Brain Mapping Division, Department of Neurology, David Geffen School of Medicine at UCLA, 90095 1769, USA
    Arch Gen Psychiatry 63:25-34. 2006
    ....
  63. ncbi request reprint Cerebellar development and clinical outcome in attention deficit hyperactivity disorder
    Susan Mackie
    Columbia University School of Medicine, New York, NY, USA
    Am J Psychiatry 164:647-55. 2007
    ....
  64. ncbi request reprint Deformation-based surface morphometry applied to gray matter deformation
    Moo K Chung
    Department of Statistics, University of Wisconsin, 1210 West Dayton Street, Madison, WI 53706 1685, USA
    Neuroimage 18:198-213. 2003
    ....
  65. ncbi request reprint Childhood neglect is associated with reduced corpus callosum area
    Martin H Teicher
    Developmental Biopsychiatry Research Program, McLean Hospital, Belmont, Massachusetts 02478, USA
    Biol Psychiatry 56:80-5. 2004
    ..Childhood abuse has been associated with abnormalities in brain development, particularly corpus callosum (CC) morphology. The impact of neglect has not been assessed, though it is the most prevalent form of childhood maltreatment...
  66. ncbi request reprint A multivariate analysis of neuroanatomic relationships in a genetically informative pediatric sample
    J Eric Schmitt
    Virginia Institute for Psychiatric and Behavioral Genetics and Departments of Psychiatry and Human Genetics, Virginia Commonwealth University, Richmond, VA 23298, USA
    Neuroimage 35:70-82. 2007
    ..These findings are concordant with prior volumetric twin studies and support radial models of brain evolution...
  67. ncbi request reprint Mapping cortical change in Alzheimer's disease, brain development, and schizophrenia
    Paul M Thompson
    Laboratory of Neuro Imaging, Brain Mapping Division, Department of Neurology, UCLA School of Medicine, Los Angeles, CA 90095 1769, USA
    Neuroimage 23:S2-18. 2004
    ..Dynamically spreading waves of gray matter loss are tracked in dementia and schizophrenia, and these sequences are related to normally occurring changes in healthy subjects of various ages...
  68. ncbi request reprint Corpus callosum morphometrics in young children with autism spectrum disorder
    Inbal Boger-Megiddo
    Department of Radiology, 5C 1, Children s Hospital and Regional Medical Center, 4800 Sand Point Way NE, Seattle, WA, 98105, USA
    J Autism Dev Disord 36:733-9. 2006
    ..Results could reflect decreased inter-hemispheric connectivity or cerebral enlargement due to increase in tissues less represented in the corpus callosum in ASD...
  69. ncbi request reprint Individual and population penalized regression splines for accelerated longitudinal designs
    Jaroslaw Harezlak
    Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Biometrics 61:1037-48. 2005
    ..Potential applications extend beyond growth studies to many other fields in which cost and feasibility constraints impose restrictions on sample size and on the numbers and timings of repeated measurements across subjects...
  70. ncbi request reprint Structural MRI and brain development
    Paul M Thompson
    Laboratory of Neuro Imaging, Brain Mapping Division, Department of Neurology, University of California, Los Angeles School of Medicine, Los Angeles, California 90095 1769, USA
    Int Rev Neurobiol 67:285-323. 2005
  71. pmc Review of twin and family studies on neuroanatomic phenotypes and typical neurodevelopment
    J Eric Schmitt
    Virginia Institute for Psychiatric and Behavioral Genetics, Medical College of Virginia, Virginia Commonwealth University, Richmond, Virginia, USA
    Twin Res Hum Genet 10:683-94. 2007
    ....
  72. pmc The epigenesis of planum temporale asymmetry in twins
    Mark A Eckert
    Department of Neuroscience, McKnight Brain Institute of the University of Florida, Gainesville, FL 32610, USA
    Cereb Cortex 12:749-55. 2002
    ..Birth weight differences were also related to twin differences in total cerebral volume, but not central sulcus asymmetry. These results suggest that exogenous perinatal factors affect the epigenesis of planar asymmetry development...