Gabi Gerlitz

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc HMGNs, DNA repair and cancer
    Gabi Gerlitz
    Protein Section, Laboratory of Metabolism, National Cancer Institute, National Institutes of Health, Building 37 Room 3122, 9000 Rockville Pike, Bethesda, MD 20892, USA
    Biochim Biophys Acta 1799:80-5. 2010
  2. pmc Efficient cell migration requires global chromatin condensation
    Gabi Gerlitz
    Protein Section, Laboratory of Metabolism, National Cancer Institute, US National Institutes of Health, 9000 Rockville Pike, Bethesda, MD 20892, USA
    J Cell Sci 123:2207-17. 2010
  3. pmc The role of chromatin structure in cell migration
    Gabi Gerlitz
    Protein Section, Laboratory of Metabolism, National Cancer Institute, US National Institutes of Health, Bethesda, MD 20892, USA
    Trends Cell Biol 21:6-11. 2011
  4. pmc Delineation of the protein module that anchors HMGN proteins to nucleosomes in the chromatin of living cells
    Tetsuya Ueda
    Protein Section, Laboratory of Metabolism, National Cancer Institute, NIH, Bethesda, MD 20892
    Mol Cell Biol 28:2872-83. 2008
  5. doi request reprint Microtubule dynamics alter the interphase nucleus
    Gabi Gerlitz
    Protein Section, Laboratory of Metabolism, National Cancer Institute, US National Institutes of Health, Bethesda, MD 20892, USA
    Cell Mol Life Sci 70:1255-68. 2013
  6. pmc Activation of ATM depends on chromatin interactions occurring before induction of DNA damage
    Yong Chul Kim
    Laboratory of Metabolism, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Nat Cell Biol 11:92-6. 2009
  7. pmc The dynamics of HMG protein-chromatin interactions in living cells
    Gabi Gerlitz
    Protein Section, Laboratory of Metabolism, National Cancer Institute, US National Institute of Health, 37 Convent Drive, Bldg 37, Bethesda, MD 20892, USA
    Biochem Cell Biol 87:127-37. 2009

Detail Information

Publications7

  1. pmc HMGNs, DNA repair and cancer
    Gabi Gerlitz
    Protein Section, Laboratory of Metabolism, National Cancer Institute, National Institutes of Health, Building 37 Room 3122, 9000 Rockville Pike, Bethesda, MD 20892, USA
    Biochim Biophys Acta 1799:80-5. 2010
    ..In addition, emerging roles for HMGN5 in cancer progression and for HMGN2 as a potential tool in cancer therapy will be discussed...
  2. pmc Efficient cell migration requires global chromatin condensation
    Gabi Gerlitz
    Protein Section, Laboratory of Metabolism, National Cancer Institute, US National Institutes of Health, 9000 Rockville Pike, Bethesda, MD 20892, USA
    J Cell Sci 123:2207-17. 2010
    ..Our results support a role for the chromatin fiber that is distinct from its known functions in genetic processes...
  3. pmc The role of chromatin structure in cell migration
    Gabi Gerlitz
    Protein Section, Laboratory of Metabolism, National Cancer Institute, US National Institutes of Health, Bethesda, MD 20892, USA
    Trends Cell Biol 21:6-11. 2011
    ..Thus, in addition to regulating genetic processes, we suggest that alterations in chromatin structure could facilitate cellular reorganizations necessary for efficient migration...
  4. pmc Delineation of the protein module that anchors HMGN proteins to nucleosomes in the chromatin of living cells
    Tetsuya Ueda
    Protein Section, Laboratory of Metabolism, National Cancer Institute, NIH, Bethesda, MD 20892
    Mol Cell Biol 28:2872-83. 2008
    ..Our studies identify a new chromatin-binding module that specifically recognizes nucleosome cores independently of DNA sequence or histone tail modifications...
  5. doi request reprint Microtubule dynamics alter the interphase nucleus
    Gabi Gerlitz
    Protein Section, Laboratory of Metabolism, National Cancer Institute, US National Institutes of Health, Bethesda, MD 20892, USA
    Cell Mol Life Sci 70:1255-68. 2013
    ..Thus, our study identified a molecular mechanism by which mechanical forces generated in the cytoplasm reshape the nuclear envelope, alter the intranuclear organization of chromatin, and affect the architecture of the interphase nucleus...
  6. pmc Activation of ATM depends on chromatin interactions occurring before induction of DNA damage
    Yong Chul Kim
    Laboratory of Metabolism, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Nat Cell Biol 11:92-6. 2009
    ..Our studies identify a new mediator of ATM activation and demonstrate a direct link between the steady-state intranuclear organization of ATM and the kinetics of its activation after DNA damage...
  7. pmc The dynamics of HMG protein-chromatin interactions in living cells
    Gabi Gerlitz
    Protein Section, Laboratory of Metabolism, National Cancer Institute, US National Institute of Health, 37 Convent Drive, Bldg 37, Bethesda, MD 20892, USA
    Biochem Cell Biol 87:127-37. 2009
    ..The versatile modulation of the interaction between HMG proteins and chromatin plays a role in processes that establish the cellular phenotype...