Mia M Gaudet

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Catechol-O-methyltransferase haplotypes and breast cancer among women on Long Island, New York
    Mia M Gaudet
    Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hil, NC 27516, USA
    Breast Cancer Res Treat 99:235-40. 2006
  2. ncbi request reprint Genetic variation of TP53, polycyclic aromatic hydrocarbon-related exposures, and breast cancer risk among women on Long Island, New York
    Mia M Gaudet
    Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, NC, USA
    Breast Cancer Res Treat 108:93-9. 2008
  3. ncbi request reprint Genetic variation in tumor necrosis factor and lymphotoxin-alpha (TNF-LTA) and breast cancer risk
    Mia M Gaudet
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
    Hum Genet 121:483-90. 2007
  4. ncbi request reprint Comprehensive assessment of genetic variation of catechol-O-methyltransferase and breast cancer risk
    Mia M Gaudet
    Division of Cancer Epidemiology, National Cancer Institute, 6120 Executive Boulevard, EPS 7055, Rockville, MD 20852, USA
    Cancer Res 66:9781-5. 2006
  5. ncbi request reprint Genetic variation of Cytochrome P450 1B1 (CYP1B1) and risk of breast cancer among Polish women
    Mia M Gaudet
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Bethesda, Maryland 20852, USA
    Pharmacogenet Genomics 16:547-53. 2006
  6. doi request reprint Genetic variation in CYP17 and endometrial cancer risk
    Mia M Gaudet
    National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    Hum Genet 123:155-62. 2008
  7. ncbi request reprint MnSOD Val-9Ala genotype, pro- and anti-oxidant environmental modifiers, and breast cancer among women on Long Island, New York
    Mia M Gaudet
    Department of Epidemiology, School of Public Health, University of North Carolina, CB 7435, Chapel Hill, NC 27599 7435, USA
    Cancer Causes Control 16:1225-34. 2005
  8. pmc Polycyclic aromatic hydrocarbon-DNA adducts and survival among women with breast cancer
    Sharon K Sagiv
    Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, NC, USA
    Environ Res 109:287-91. 2009
  9. ncbi request reprint Associations between breast cancer risk and the catalase genotype, fruit and vegetable consumption, and supplement use
    Jiyoung Ahn
    Department of Epidemiology, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    Am J Epidemiol 162:943-52. 2005
  10. pmc HSD17B1 genetic variants and hormone receptor-defined breast cancer
    Mia M Gaudet
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA
    Cancer Epidemiol Biomarkers Prev 17:2766-72. 2008

Detail Information

Publications45

  1. ncbi request reprint Catechol-O-methyltransferase haplotypes and breast cancer among women on Long Island, New York
    Mia M Gaudet
    Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hil, NC 27516, USA
    Breast Cancer Res Treat 99:235-40. 2006
    ....
  2. ncbi request reprint Genetic variation of TP53, polycyclic aromatic hydrocarbon-related exposures, and breast cancer risk among women on Long Island, New York
    Mia M Gaudet
    Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, NC, USA
    Breast Cancer Res Treat 108:93-9. 2008
    ..p53 participates in cell cycle control, programmed cell death/apoptosis, and DNA repair, all pathways involved in carcinogenesis. TP53 variants may influence p53 function...
  3. ncbi request reprint Genetic variation in tumor necrosis factor and lymphotoxin-alpha (TNF-LTA) and breast cancer risk
    Mia M Gaudet
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
    Hum Genet 121:483-90. 2007
    ..Additional studies are required to replicate these findings and to determine whether rs361525 is a causative SNP or is a marker of a causative SNP...
  4. ncbi request reprint Comprehensive assessment of genetic variation of catechol-O-methyltransferase and breast cancer risk
    Mia M Gaudet
    Division of Cancer Epidemiology, National Cancer Institute, 6120 Executive Boulevard, EPS 7055, Rockville, MD 20852, USA
    Cancer Res 66:9781-5. 2006
    ..The suggestion of increased risk associated with a haplotype in the 3' UTR of COMT needs to be confirmed in independent study populations...
  5. ncbi request reprint Genetic variation of Cytochrome P450 1B1 (CYP1B1) and risk of breast cancer among Polish women
    Mia M Gaudet
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Bethesda, Maryland 20852, USA
    Pharmacogenet Genomics 16:547-53. 2006
    ..The present study provides strong evidence against the existence of a substantial overall association between common genetic variation in CYP1B1 and breast cancer risk...
  6. doi request reprint Genetic variation in CYP17 and endometrial cancer risk
    Mia M Gaudet
    National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    Hum Genet 123:155-62. 2008
    ..Further evaluation in consortia is necessary to confirm potential weak associations between common variation in CYP17 and endometrial cancer risk and to address the concern of publication bias...
  7. ncbi request reprint MnSOD Val-9Ala genotype, pro- and anti-oxidant environmental modifiers, and breast cancer among women on Long Island, New York
    Mia M Gaudet
    Department of Epidemiology, School of Public Health, University of North Carolina, CB 7435, Chapel Hill, NC 27599 7435, USA
    Cancer Causes Control 16:1225-34. 2005
    ..This study provides little evidence that variation in Val-9Ala polymorphism of MnSOD alone or through substantial interaction with key exposures believed to be pro- or anti-oxidant properties influences breast cancer risk...
  8. pmc Polycyclic aromatic hydrocarbon-DNA adducts and survival among women with breast cancer
    Sharon K Sagiv
    Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, NC, USA
    Environ Res 109:287-91. 2009
    ..Results from this large population-based study do not provide strong support for an association between detectable PAH-DNA adducts and survival among women with breast cancer, except perhaps among those receiving radiation treatment...
  9. ncbi request reprint Associations between breast cancer risk and the catalase genotype, fruit and vegetable consumption, and supplement use
    Jiyoung Ahn
    Department of Epidemiology, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    Am J Epidemiol 162:943-52. 2005
    ..CC genotypes were prevalent in approximately 64% of controls; thus, the preventive potential for fruit consumption has widespread implications...
  10. pmc HSD17B1 genetic variants and hormone receptor-defined breast cancer
    Mia M Gaudet
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA
    Cancer Epidemiol Biomarkers Prev 17:2766-72. 2008
    ..Associations between HSD17B1 genotypes and risk for ER- breast cancer were inconsistent across studies and should be studied further...
  11. ncbi request reprint Active and passive cigarette smoke and breast cancer survival
    Sharon K Sagiv
    Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, NC, USA
    Ann Epidemiol 17:385-93. 2007
    ..The association between active and passive cigarette smoking before breast cancer diagnosis and survival was investigated among a cohort of invasive breast cancer cases (n = 1273) participating in a population-based case-control study...
  12. ncbi request reprint Effects of glutathione S-transferase A1 (GSTA1) genotype and potential modifiers on breast cancer risk
    Jiyoung Ahn
    Department of Epidemiology, Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    Carcinogenesis 27:1876-82. 2006
    ..These data indicate that GSTA1 genotypes related to reduced GSTA1 expression are associated with increased breast cancer primarily among women with lower consumption of cruciferous vegetables and among current smokers...
  13. pmc Common genetic variations in the LEP and LEPR genes, obesity and breast cancer incidence and survival
    Rebecca J Cleveland
    Department of Nutrition, School of Public Health, University of North Carolina, Chapel Hill, NC 27599 7461, USA
    Breast Cancer Res Treat 120:745-52. 2010
    ..In summary, our results show that a common variant in LEP may be associated with the risk of developing breast cancer supporting the hypothesis that leptin is involved in breast carcinogenesis...
  14. ncbi request reprint Polycyclic aromatic hydrocarbon-DNA adducts and breast cancer: a pooled analysis
    Marilie D Gammon
    Department of Epidemiology, University of North Carolina School of Public Health, Chapel Hill, North Carolina 27599 7435, USA
    Arch Environ Health 59:640-9. 2004
    ..These data provide only modest support for an association between PAH-DNA adducts and breast cancer development...
  15. ncbi request reprint Dietary flavonoid intake and breast cancer survival among women on Long Island
    Brian N Fink
    Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, North Carolina, USA
    Cancer Epidemiol Biomarkers Prev 16:2285-92. 2007
    ..However, the effects of flavonoids on survival are not known. In a population-based cohort of breast cancer patients, we investigated whether dietary flavonoid intake before diagnosis is associated with subsequent survival...
  16. ncbi request reprint Myeloperoxidase genotype, fruit and vegetable consumption, and breast cancer risk
    Jiyoung Ahn
    Department of Epidemiology, Roswell Park Cancer Institute, Buffalo, New York, USA
    Cancer Res 64:7634-9. 2004
    ....
  17. pmc Genetic variation in the androgen receptor gene and endometrial cancer risk
    Hannah P Yang
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD, USA
    Cancer Epidemiol Biomarkers Prev 18:585-9. 2009
    ..Results from our study, taken together with previously published studies, provide little evidence of a consistent association between common genetic variation in AR and endometrial cancer risk...
  18. doi request reprint Nutrient pathways and breast cancer risk: the Long Island Breast Cancer Study Project
    Patrick T Bradshaw
    Department of Nutrition, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
    Nutr Cancer 65:345-54. 2013
    ..Our study emphasizes the importance of accounting for multiple nutrient pathways when examining associations between dietary intake and breast cancer...
  19. pmc An examination of male and female odds ratios by BMI, cigarette smoking, and alcohol consumption for cancers of the oral cavity, pharynx, and larynx in pooled data from 15 case-control studies
    Jay H Lubin
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Rockville, MD 20852, USA
    Cancer Causes Control 22:1217-31. 2011
    ....
  20. ncbi request reprint No association between glutathione peroxidase Pro198Leu polymorphism and breast cancer risk
    Jiyoung Ahn
    Department of Epidemiology, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA
    Cancer Epidemiol Biomarkers Prev 14:2459-61. 2005
  21. pmc Five polymorphisms and breast cancer risk: results from the Breast Cancer Association Consortium
    Mia M Gaudet
    Department of Epidemiology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Cancer Epidemiol Biomarkers Prev 18:1610-6. 2009
    ....
  22. ncbi request reprint Fruits, vegetables, and micronutrient intake in relation to breast cancer survival
    Brian N Fink
    Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, NC 27599 7435, USA
    Breast Cancer Res Treat 98:199-208. 2006
    ..To determine whether fruit, vegetable, and micronutrient intake 1 year prior to breast cancer diagnosis is associated with a reduction in the subsequent risk of all-cause or breast cancer-specific mortality...
  23. ncbi request reprint Cooked meat and risk of breast cancer--lifetime versus recent dietary intake
    Susan E Steck
    Department of Nutrition, School of Public Health, University of North Carolina, Chapel Hill, NC, USA
    Epidemiology 18:373-82. 2007
    ..Polycyclic aromatic hydrocarbons (PAHs) and heterocyclic amines (HCAs) are carcinogens formed in or on the surface of well-done meat, cooked at high temperature...
  24. pmc Genetic variation in SIPA1 in relation to breast cancer risk and survival after breast cancer diagnosis
    Mia M Gaudet
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
    Int J Cancer 124:1716-20. 2009
    ..02, 0.88-1.17; 0.90, 0.72-1.11; 1.04, 0.90-1.21, respectively). Our results do not support a relationship between SIPA1 polymorphisms and breast cancer risk or subsequent survival...
  25. ncbi request reprint Fruits, vegetables, and micronutrients in relation to breast cancer modified by menopause and hormone receptor status
    Mia M Gaudet
    Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, North Carolina 27599 7435, USA
    Cancer Epidemiol Biomarkers Prev 13:1485-94. 2004
    ..Our results support an inverse association for fruit and vegetable intake among postmenopausal but not premenopausal breast cancer, which may be more pronounced among women with ER+ tumors...
  26. pmc Prevalence and predictors of antioxidant supplement use during breast cancer treatment: the Long Island Breast Cancer Study Project
    Heather Greenlee
    Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA
    Cancer 115:3271-82. 2009
    ..The authors of this report analyzed the prevalence of and factors associated with antioxidant supplement use during breast cancer (BC) treatment among women who participated in the Long Island Breast Cancer Study Project...
  27. ncbi request reprint Residential environmental exposures and other characteristics associated with detectable PAH-DNA adducts in peripheral mononuclear cells in a population-based sample of adult females
    Sumitra Shantakumar
    Department of Epidemiology, CB 7435 McGavran Greenberg Hall, University of North Carolina School of Public Health, Chapel Hill, North Carolina 27599 7435, USA
    J Expo Anal Environ Epidemiol 15:482-90. 2005
    ..These data suggest that PAH-DNA adducts detected in a population-based sample of adult women with ambient exposure levels reflect some key residential PAH exposure sources assessed in this study, such as cigarette smoking...
  28. pmc Common genetic variation in the sex hormone metabolic pathway and endometrial cancer risk: pathway-based evaluation of candidate genes
    Hannah P Yang
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20852, USA
    Carcinogenesis 31:827-33. 2010
    ..Associations with variants in other genes have been suggested, but findings have been inconsistent...
  29. pmc Endometrial cancer and genetic variation in PTEN, PIK3CA, AKT1, MLH1, and MSH2 within a population-based case-control study
    James V Lacey
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
    Gynecol Oncol 120:167-73. 2011
    ..We assessed whether common genetic variation in PTEN, PIK3CA, AKT1, MLH1, and MSH2-genes that reportedly are frequently altered in endometrial cancer-was associated with risk of endometrial cancer...
  30. pmc Genetic variation in PRL and PRLR, and relationships with serum prolactin levels and breast cancer risk: results from a population-based case-control study in Poland
    Sarah J Nyante
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Rockville, MD 20852, USA
    Breast Cancer Res 13:R42. 2011
    ..Thus, we examined the relationship between single nucleotide polymorphisms (SNPs) in PRL and PRLR, serum prolactin levels and breast cancer risk in a population-based case-control study...
  31. pmc Body mass index, cigarette smoking, and alcohol consumption and cancers of the oral cavity, pharynx, and larynx: modeling odds ratios in pooled case-control data
    Jay H Lubin
    Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Rockville, MD 20852, USA
    Am J Epidemiol 171:1250-61. 2010
    ....
  32. pmc Associations between polycyclic aromatic hydrocarbon-related exposures and p53 mutations in breast tumors
    Irina Mordukhovich
    Department of Epidemiology, University of North Carolina, Chapel Hill, North Carolina 27599 7435, USA
    Environ Health Perspect 118:511-8. 2010
    ..Objectives: We hypothesized that associations of PAH-related exposures with breast cancer would differ according to tumor p53 mutation status, effect, type, and number...
  33. pmc Haplotype structure in Ashkenazi Jewish BRCA1 and BRCA2 mutation carriers
    Kate M Im
    Center for Cancer Research, Cancer Inflammation Program, Human Genetics Section, National Cancer Institute, Frederick, MD, USA
    Hum Genet 130:685-99. 2011
    ....
  34. ncbi request reprint The epidemiology of gastric cancer
    Mary Beth Terry
    Columbia University Mailman School of Public Health, Department of Epidemiology, New York, NY 10032, USA
    Semin Radiat Oncol 12:111-27. 2002
    ..Future epidemiologic studies that include information on site of origin as well as molecular markers promise to yield more homogeneous classification of case groups, which will enhance identification of underlying disease processes...
  35. pmc Detectable clonal mosaicism and its relationship to aging and cancer
    Kevin B Jacobs
    Division of Cancer Epidemiology and Genetics, National Cancer Institute NCI, Rockville, Maryland, USA
    Nat Genet 44:651-8. 2012
    ..4; P = 3.8 × 10(-11)). These findings underscore the time-dependent nature of somatic events in the etiology of cancer and potentially other late-onset diseases...
  36. ncbi request reprint Calcium intake and colorectal adenoma in a US colorectal cancer early detection program
    Ulrike Peters
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
    Am J Clin Nutr 80:1358-65. 2004
    ..Calcium can reduce the risk of colorectal tumors by binding secondary bile and fatty acids, which leads to antiproliferative effects in the bowel, or by acting directly on the colonic epithelium, which affects differentiation and apoptosis...
  37. ncbi request reprint Ethnic differences in the nutrient intake adequacy of premenopausal US women: results from the Third National Health Examination Survey
    Lenore Arab
    Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    J Am Diet Assoc 103:1008-14. 2003
    ..To examine the adequacy of dietary intake of calcium; folate; and vitamins C, D, E, B-6, and B-12 in premenopausal US women of differing ethnicity...
  38. ncbi request reprint Genetic polymorphisms in the one-carbon metabolism pathway and breast cancer risk: a population-based case-control study and meta-analyses
    Jolanta Lissowska
    Department of Cancer Epidemiology and Prevention, Cancer Center and M Sklodowska Curie Institute of Oncology, Warsaw, Poland
    Int J Cancer 120:2696-703. 2007
    ..In conclusion, this report does not support a substantial overall association between the evaluated polymorphisms in the one-carbon metabolism pathway and breast cancer risk...
  39. ncbi request reprint IGHMBP2 Thr671Ala polymorphism might be a modifier for the effects of cigarette smoking and PAH-DNA adducts to breast cancer risk
    Jing Shen
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, USA
    Breast Cancer Res Treat 99:1-7. 2006
    ..Additional studies focused on the biological function of the variant-G allele and interactions with other genetic polymorphisms are necessary to confirm our findings...
  40. ncbi request reprint OGG1 polymorphisms and breast cancer risk
    Pavel Rossner
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, New York, USA
    Cancer Epidemiol Biomarkers Prev 15:811-5. 2006
    ..In addition, data on functionality of these polymorphisms are crucial to understand if these modest differences are important...
  41. ncbi request reprint Polymorphisms in XRCC1 modify the association between polycyclic aromatic hydrocarbon-DNA adducts, cigarette smoking, dietary antioxidants, and breast cancer risk
    Jing Shen
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    Cancer Epidemiol Biomarkers Prev 14:336-42. 2005
    ..Further understanding of the biological function of XRCC1 variants and their interactions with PAH-DNA adducts, antioxidants, and other genes in the pathway are needed...
  42. ncbi request reprint MGMT genotype modulates the associations between cigarette smoking, dietary antioxidants and breast cancer risk
    Jing Shen
    Department of Environmental Health Sciences, Columbia University, New York, NY 10032, USA
    Carcinogenesis 26:2131-7. 2005
    ....
  43. ncbi request reprint A functional 19-base pair deletion polymorphism of dihydrofolate reductase (DHFR) and risk of breast cancer in multivitamin users
    Xinran Xu
    Departments of Community and Preventive Medicine and Epidemiology and Medicine, Columbia University, New York, NY, USA
    Am J Clin Nutr 85:1098-102. 2007
    ..Folic acid from multivitamins needs to be reduced by DHFR before it participates in cellular reactions...
  44. ncbi request reprint Relationship between urinary 15-F2t-isoprostane and 8-oxodeoxyguanosine levels and breast cancer risk
    Pavel Rossner
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    Cancer Epidemiol Biomarkers Prev 15:639-44. 2006
    ..In summary, our results suggest that urinary markers of lipid peroxidation and oxidative DNA damage may be associated with breast cancer risk...
  45. ncbi request reprint Plasma protein carbonyl levels and breast cancer risk
    Pavel Rossner
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, USA
    J Cell Mol Med 11:1138-48. 2007
    ..8, 95% CI = 1.2-2.6) compared to women with levels below the median for both markers of oxidative stress. In summary, our results suggest that increased plasma protein carbonyl levels may be associated with breast cancer risk...