D Travis Gallagher

Summary

Affiliation: National Institute of Standards and Technology
Country: USA

Publications

  1. ncbi The crystal structure of chorismate lyase shows a new fold and a tightly retained product
    D T Gallagher
    National Institute of Standards and Technology, Chemical Science and Technology Laboratory, Biotechnology Division, Gaithersburg, Maryland 20899 8312, USA
    Proteins 44:304-11. 2001
  2. ncbi Structure of the class IV adenylyl cyclase reveals a novel fold
    D Travis Gallagher
    Biochemical Science Division, National Institute of Standards and Technology, Gaithersburg, MD 20899 8310, USA
    J Mol Biol 362:114-22. 2006
  3. ncbi Structure of alanine dehydrogenase from Archaeoglobus: active site analysis and relation to bacterial cyclodeaminases and mammalian mu crystallin
    D T Gallagher
    Biotechnology Division of the National Institute of Standards and Technology, Gaithersburg, MD 20899 8312, USA
    J Mol Biol 342:119-30. 2004
  4. ncbi Profound asymmetry in the structure of the cAMP-free cAMP Receptor Protein (CRP) from Mycobacterium tuberculosis
    D Travis Gallagher
    Biochemical Science Division, National Institute of Standards and Technology, Gaithersburg, Maryland, 20899, USA
    J Biol Chem 284:8228-32. 2009
  5. ncbi Active-site structure of class IV adenylyl cyclase and transphyletic mechanism
    D Travis Gallagher
    Biochemical Science Division, Chemical Science and Technology Laboratory, National Institute of Standards and Technology, Gaithersburg, MD 20899, USA
    J Mol Biol 405:787-803. 2011
  6. ncbi Crystallization and 1.1-A diffraction of chorismate lyase from Escherichia coli
    C Stover
    NIST Biotechnology Division, Gaithersburg, Maryland 20899 8312, USA
    J Struct Biol 129:96-9. 2000
  7. ncbi Crystallization of the class IV adenylyl cyclase from Yersinia pestis
    Natasha Smith
    Biotechnology Division, National Institute of Standards and Technology, Gaithersburg, MD 20899 8310, USA
    Acta Crystallogr Sect F Struct Biol Cryst Commun 62:200-4. 2006
  8. ncbi Crystallization and phasing of alanine dehydrogenase from Archaeoglobus fulgidus
    Natasha Smith
    Biotechnology Division of the National Institute of Standards and Technology, Gaithersburg, MD 20899 8312, USA
    Acta Crystallogr D Biol Crystallogr 59:2328-31. 2003
  9. ncbi Local and global control mechanisms in allosteric threonine deaminase
    D Travis Gallagher
    Biotech Division, Chemical Science and Technology Lab, National Institute of Standards and Technology, Gaithersburg, MD 20899, USA
    Methods Enzymol 380:85-106. 2004
  10. ncbi Chorismate lyase: kinetics and engineering for stability
    M J Holden
    National Institute of Standards and Technology, Chemical Science and Technology Laboratory, Biotechnology Division, 100 Bureau Drive, Gaithersburg, MD 20899 8312, USA
    Biochim Biophys Acta 1594:160-7. 2002

Collaborators

Detail Information

Publications15

  1. ncbi The crystal structure of chorismate lyase shows a new fold and a tightly retained product
    D T Gallagher
    National Institute of Standards and Technology, Chemical Science and Technology Laboratory, Biotechnology Division, Gaithersburg, Maryland 20899 8312, USA
    Proteins 44:304-11. 2001
    ..Implications for the biological function of the high product binding are considered in light of the unique cellular role of 4HB, which is produced by cytoplasmic CL but is used by the membrane-bound enzyme 4HB octaprenyltransferase...
  2. ncbi Structure of the class IV adenylyl cyclase reveals a novel fold
    D Travis Gallagher
    Biochemical Science Division, National Institute of Standards and Technology, Gaithersburg, MD 20899 8310, USA
    J Mol Biol 362:114-22. 2006
    ..Homologs of Y. pestis AC-IV, including human thiamine triphosphatase, span the three kingdoms of life and delineate an ancient family of phosphonucleotide processing enzymes...
  3. ncbi Structure of alanine dehydrogenase from Archaeoglobus: active site analysis and relation to bacterial cyclodeaminases and mammalian mu crystallin
    D T Gallagher
    Biotechnology Division of the National Institute of Standards and Technology, Gaithersburg, MD 20899 8312, USA
    J Mol Biol 342:119-30. 2004
    ....
  4. ncbi Profound asymmetry in the structure of the cAMP-free cAMP Receptor Protein (CRP) from Mycobacterium tuberculosis
    D Travis Gallagher
    Biochemical Science Division, National Institute of Standards and Technology, Gaithersburg, Maryland, 20899, USA
    J Biol Chem 284:8228-32. 2009
    ..Comparison of the structures of apo MtbCRP and DNA-bound EcCRP shows how DNA binding would be inhibited in the absence of cAMP and supports a mechanism involving functional asymmetry in apoCRP...
  5. ncbi Active-site structure of class IV adenylyl cyclase and transphyletic mechanism
    D Travis Gallagher
    Biochemical Science Division, Chemical Science and Technology Laboratory, National Institute of Standards and Technology, Gaithersburg, MD 20899, USA
    J Mol Biol 405:787-803. 2011
    ..With resolutions of 1.6-1.7 Å, these are the most detailed active-site ligand complexes for any class of this ubiquitous signaling enzyme...
  6. ncbi Crystallization and 1.1-A diffraction of chorismate lyase from Escherichia coli
    C Stover
    NIST Biotechnology Division, Gaithersburg, Maryland 20899 8312, USA
    J Struct Biol 129:96-9. 2000
    ..Protein aggregation was largely eliminated by mutating the protein's two cysteines to serines. The double mutant retains full enzymatic activity and crystallizes in three new forms, one of which (triclinic) diffracts to 1.1-A resolution...
  7. ncbi Crystallization of the class IV adenylyl cyclase from Yersinia pestis
    Natasha Smith
    Biotechnology Division, National Institute of Standards and Technology, Gaithersburg, MD 20899 8310, USA
    Acta Crystallogr Sect F Struct Biol Cryst Commun 62:200-4. 2006
    ..The native construct has been produced as a selenomethionine derivative and crystallized for phasing and structure determination...
  8. ncbi Crystallization and phasing of alanine dehydrogenase from Archaeoglobus fulgidus
    Natasha Smith
    Biotechnology Division of the National Institute of Standards and Technology, Gaithersburg, MD 20899 8312, USA
    Acta Crystallogr D Biol Crystallogr 59:2328-31. 2003
    ..Before and after derivatization, these crystals diffracted to 2.5 A using synchrotron radiation. Multiwavelength diffraction data were collected from the non-isomorphous iridium derivative, enabling structure determination...
  9. ncbi Local and global control mechanisms in allosteric threonine deaminase
    D Travis Gallagher
    Biotech Division, Chemical Science and Technology Lab, National Institute of Standards and Technology, Gaithersburg, MD 20899, USA
    Methods Enzymol 380:85-106. 2004
  10. ncbi Chorismate lyase: kinetics and engineering for stability
    M J Holden
    National Institute of Standards and Technology, Chemical Science and Technology Laboratory, Biotechnology Division, 100 Bureau Drive, Gaithersburg, MD 20899 8312, USA
    Biochim Biophys Acta 1594:160-7. 2002
    ..The biological function of the unusual product retention remains uncertain, but may involve a mechanism of directed delivery to the membrane-bound enzyme that follows CL in the ubiquinone pathway...
  11. ncbi Polymorphous crystallization and diffraction of threonine deaminase from Escherichia coli
    D T Gallagher
    Center for Advanced Research in Biotechnology of the University of Maryland Biotechnology Institute and the National Institute of Standards and Technology, 9600 Gudelsky Drive, Rockville, MD 20850, USA
    Acta Crystallogr D Biol Crystallogr 54:467-9. 1998
    ..Diffraction data sets to 2.8 A resolution (native) and 2. 9 A resolution (isomorphous uranyl derivative) have been collected from a third crystal form in space group I222...
  12. ncbi Structure and control of pyridoxal phosphate dependent allosteric threonine deaminase
    D T Gallagher
    University of Maryland, Biotechnology Institute, National Institute of Standards and Technology 9600 Gudelsky Drive, Rockville, Maryland 20850, USA
    Structure 6:465-75. 1998
    ..This enzyme is thus a useful model system for studying the structural basis of allosteric control mechanisms...
  13. ncbi Fluorescence resonance energy transfer between donor-acceptor pair on two oligonucleotides hybridized adjacently to DNA template
    L Wang
    Biotechnology Division, National Institute of Standards and Technology, 100 Bureau Drive, Stop 8312, Gaithersburg, Maryland 20899 8312, USA
    Biopolymers 72:401-12. 2003
    ..The study identifies important parameters that determine FRET response in applications such as real-time PCR...
  14. ncbi Structure and lability of archaeal dehydroquinase
    Natasha N Smith
    National Institute of Standards and Technology, Biochemical Science Division, Gaithersburg, MD 20899 8312, USA
    Acta Crystallogr Sect F Struct Biol Cryst Commun 64:886-92. 2008
    ..Structural features that may contribute to stability, in particular ionic factors, are examined and the implications of having a T(m) below the organism's growth temperature are considered...
  15. ncbi Structure of C73G putidaredoxin from Pseudomonas putida
    Natasha Smith
    Biotechnology Division of the National Institute of Standards and Technology, Gaithersburg, MD 20899-8312, USA
    Acta Crystallogr D Biol Crystallogr 60:816-22. 2004
    ..In addition, the Cys45 amide group donates a hydrogen bond to cluster sulfur S1, with Ala46 adopting an Lalpha conformation, in all three molecules in the crystal...