M H Gail

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi Using multiple risk models with preventive interventions
    Mitchell H Gail
    Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20892 7244, USA
    Stat Med 31:2687-96. 2012
  2. ncbi Potential usefulness of single nucleotide polymorphisms to identify persons at high cancer risk: an evaluation of seven common cancers
    Ju Hyun Park
    National Cancer Institute, Rockville, MD 20852 7244, USA
    J Clin Oncol 30:2157-62. 2012
  3. ncbi Fifteen-year effects of Helicobacter pylori, garlic, and vitamin treatments on gastric cancer incidence and mortality
    Jun Ling Ma
    Key Laboratory of Carcinogenesis and Translational Research Ministry of Education, Peking University School of Oncology, Beijing Cancer Hospital and Beijing Institute for Cancer Research, Beijing, China
    J Natl Cancer Inst 104:488-92. 2012
  4. ncbi Probability of detecting disease-associated single nucleotide polymorphisms in case-control genome-wide association studies
    Mitchell H Gail
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, EPS 8032, Bethesda, MD 20892 7244, USA
    Biostatistics 9:201-15. 2008
  5. ncbi Discriminatory accuracy from single-nucleotide polymorphisms in models to predict breast cancer risk
    Mitchell H Gail
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Rm 8032, Bethesda, MD 20892 7244, USA
    J Natl Cancer Inst 100:1037-41. 2008
  6. ncbi Estimation and interpretation of models of absolute risk from epidemiologic data, including family-based studies
    Mitchell H Gail
    Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, EPS 8032, Bethesda, MD 20892 7244, USA
    Lifetime Data Anal 14:18-36. 2008
  7. ncbi Probability that a two-stage genome-wide association study will detect a disease-associated snp and implications for multistage designs
    M H Gail
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7244, US
    Ann Hum Genet 72:812-20. 2008
  8. ncbi Personalized estimates of breast cancer risk in clinical practice and public health
    Mitchell H Gail
    Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethedsa, MD, USA
    Stat Med 30:1090-104. 2011
  9. ncbi A factorial trial including garlic supplements assesses effect in reducing precancerous gastric lesions
    Mitchell H Gail
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
    J Nutr 136:813S-815S. 2006
  10. ncbi Secular stability and reliability of measurements of the percentage of dense tissue on mammograms
    Jacques Benichou
    Department of Biostatistics, University of Rouen Medical School and Rouen University Hospital, 76031 Rouen Cedex, France
    Cancer Detect Prev 27:266-74. 2003

Detail Information

Publications93

  1. ncbi Using multiple risk models with preventive interventions
    Mitchell H Gail
    Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20892 7244, USA
    Stat Med 31:2687-96. 2012
    ..Depending on the discriminatory accuracies of the risk models, there may be considerable advantage to modeling the risks of more than one health outcome...
  2. ncbi Potential usefulness of single nucleotide polymorphisms to identify persons at high cancer risk: an evaluation of seven common cancers
    Ju Hyun Park
    National Cancer Institute, Rockville, MD 20852 7244, USA
    J Clin Oncol 30:2157-62. 2012
    ..To estimate the likely number and predictive strength of cancer-associated single nucleotide polymorphisms (SNPs) that are yet to be discovered for seven common cancers...
  3. ncbi Fifteen-year effects of Helicobacter pylori, garlic, and vitamin treatments on gastric cancer incidence and mortality
    Jun Ling Ma
    Key Laboratory of Carcinogenesis and Translational Research Ministry of Education, Peking University School of Oncology, Beijing Cancer Hospital and Beijing Institute for Cancer Research, Beijing, China
    J Natl Cancer Inst 104:488-92. 2012
    ..Vitamin treatment was associated with statistically significantly fewer deaths from gastric or esophageal cancer, a secondary endpoint (HR = 0.51, 95% CI = 0.30 to 0.87; P = .014)...
  4. ncbi Probability of detecting disease-associated single nucleotide polymorphisms in case-control genome-wide association studies
    Mitchell H Gail
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, EPS 8032, Bethesda, MD 20892 7244, USA
    Biostatistics 9:201-15. 2008
    ..A large initial CCGWAS is desirable if genetic effects are small or if the cost of a follow-up study is large...
  5. ncbi Discriminatory accuracy from single-nucleotide polymorphisms in models to predict breast cancer risk
    Mitchell H Gail
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Rm 8032, Bethesda, MD 20892 7244, USA
    J Natl Cancer Inst 100:1037-41. 2008
    ....
  6. ncbi Estimation and interpretation of models of absolute risk from epidemiologic data, including family-based studies
    Mitchell H Gail
    Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, EPS 8032, Bethesda, MD 20892 7244, USA
    Lifetime Data Anal 14:18-36. 2008
    ....
  7. ncbi Probability that a two-stage genome-wide association study will detect a disease-associated snp and implications for multistage designs
    M H Gail
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7244, US
    Ann Hum Genet 72:812-20. 2008
    ..g. pi(sample)<or= 0.25) should be avoided, and that additional genotyping in earlier studies with small first stages will yield previously unselected disease-associated SNPs...
  8. ncbi Personalized estimates of breast cancer risk in clinical practice and public health
    Mitchell H Gail
    Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethedsa, MD, USA
    Stat Med 30:1090-104. 2011
    ..High discriminatory accuracy of the risk model, in addition to good calibration, is desirable in this application, and the risk assessment should not be expensive in comparison with the intervention...
  9. ncbi A factorial trial including garlic supplements assesses effect in reducing precancerous gastric lesions
    Mitchell H Gail
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA
    J Nutr 136:813S-815S. 2006
    ..This paper describes the design and initial findings on treatment compliance, completeness of follow-up data, and eradication of Helicobacter pylori...
  10. ncbi Secular stability and reliability of measurements of the percentage of dense tissue on mammograms
    Jacques Benichou
    Department of Biostatistics, University of Rouen Medical School and Rouen University Hospital, 76031 Rouen Cedex, France
    Cancer Detect Prev 27:266-74. 2003
    ..Among women who developed breast cancer, the baseline mammographic density of the ipsilateral (diseased) breast was 0.53 (95% confidence interval (CI) 0.20-0.86) percentage units higher than in the contralateral breast...
  11. ncbi Projecting individualized absolute invasive breast cancer risk in African American women
    Mitchell H Gail
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Executive Plaza South Rm 8032, Bethesda, MD 20892 7244, USA
    J Natl Cancer Inst 99:1782-92. 2007
    ..We developed a model for projecting absolute risk of invasive breast cancer in African American women and compared its projections with those from the Breast Cancer Risk Assessment Tool...
  12. ncbi Value of adding single-nucleotide polymorphism genotypes to a breast cancer risk model
    Mitchell H Gail
    Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Rm 8032, Bethesda, MD 20892 7244, USA
    J Natl Cancer Inst 101:959-63. 2009
    ..607 to 0.632...
  13. ncbi On criteria for evaluating models of absolute risk
    Mitchell H Gail
    Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Executive Plaza South, EPS 8032, Bethesda, MD 20892 7244, USA
    Biostatistics 6:227-39. 2005
    ..These examples indicate that the usefulness of a general criterion such as concordance depends on the application, and that using specific loss functions can lead to more appropriate assessments...
  14. ncbi An intervention trial to inhibit the progression of precancerous gastric lesions: compliance, serum micronutrients and S-allyl cysteine levels, and toxicity
    W C You
    National Cancer Institute, Division of Cancer Epidemiology and Genetics, Bethesda, MD 20892, USA
    Eur J Cancer Prev 10:257-63. 2001
    ..No significant differences in side-effects were observed between the placebo treatment group and the vitamins/mineral and garlic preparation treatment groups during the 39-month trial period...
  15. ncbi Evolution of precancerous lesions in a rural Chinese population at high risk of gastric cancer
    W C You
    National Cancer Institute, Bethesda, MD, USA
    Int J Cancer 83:615-9. 1999
    ..Int. J. Cancer, 83:615-619, 1999. Published 1999 Wiley-Liss, Inc...
  16. ncbi Gastric dysplasia and gastric cancer: Helicobacter pylori, serum vitamin C, and other risk factors
    W C You
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 7244, USA
    J Natl Cancer Inst 92:1607-12. 2000
    ..To identify such determinants, we launched a follow-up study in 1989-1990 among 3433 adults in Linqu County, China, a region with very high rates of gastric cancer...
  17. ncbi Designing studies to estimate the penetrance of an identified autosomal dominant mutation: cohort, case-control, and genotyped-proband designs
    M H Gail
    Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20892 7368, USA
    Genet Epidemiol 16:15-39. 1999
    ....
  18. ncbi Validation studies for models projecting the risk of invasive and total breast cancer incidence
    J P Costantino
    National Surgical Adjuvant Breast and Bowel Project, Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, PA, USA
    J Natl Cancer Inst 91:1541-8. 1999
    ..We assessed the validity of both models by employing data from women enrolled in the Breast Cancer Prevention Trial...
  19. ncbi Helicobacter pylori infection in rural China: exposure to domestic animals during childhood and adulthood
    L M Brown
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892 7244, USA
    Scand J Infect Dis 33:686-91. 2001
    ..These findings suggest that zoonotic transmission, including that from domestic cats, is an unlikely route of H. pylori infection in this rural Chinese population...
  20. ncbi Estimation of effect size distribution from genome-wide association studies and implications for future discoveries
    Ju Hyun Park
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, US Department of Health and Human Services, Rockville, Maryland, USA
    Nat Genet 42:570-5. 2010
    ..However, for BPC cancers, which have modest familial aggregation, our analysis suggests that risk models based on common variants alone will have modest discriminatory power (63.5% area under curve), even with new discoveries...
  21. ncbi Breast-cancer risk in BRCA-mutation-negative women from BRCA-mutation-positive families
    Hormuzd A Katki
    Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
    Lancet Oncol 8:1042-3. 2007
  22. ncbi Population attributable risks of esophageal and gastric cancers
    Lawrence S Engel
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
    J Natl Cancer Inst 95:1404-13. 2003
    ..Herein, we estimate the population attributable risks (PARs) for various risk factors observed in a multicenter population-based case-control study...
  23. ncbi Weighing the risks and benefits of tamoxifen treatment for preventing breast cancer
    M H Gail
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
    J Natl Cancer Inst 91:1829-46. 1999
    ..Our study was undertaken to develop tools to identify women for whom the benefits outweigh the risks...
  24. ncbi Helicobacter pylori prevalence and CagA status among children in two counties of China with high and low risks of gastric cancer
    W C You
    National Cancer Institute, Bethesda, MD 20892-7244, USA
    Ann Epidemiol 11:543-6. 2001
    ..CONCLUSIONS: The prevalence of H. pylori was nearly three times higher among children in Linqu than in Cangshan, which may contribute to the large differential in gastric cancer rates for two neighboring populations in Shandong Province...
  25. ncbi Spectrum of AIDS-associated malignant disorders
    J J Goedert
    Viral Epidemiology Branch, National Cancer Institute, Rockville, MD, USA
    Lancet 351:1833-9. 1998
    ..To clarify which types of cancer result from AIDS, we compared the cancer experiences of people with AIDS with those of the general population by matching population-based cancer and AIDS registries in the USA and Puerto Rico...
  26. ncbi Two criteria for evaluating risk prediction models
    R M Pfeiffer
    Biostatistics Branch, National Cancer Institute, 6120 Executive Boulevard, Bethesda, Maryland 20892, USA
    Biometrics 67:1057-65. 2011
    ..We develop new methods, based on influence functions, for inference for a single risk model, and also for comparing the PCFs and PNFs of two risk models, both of which were evaluated in the same validation data...
  27. ncbi Analysis of a two-stage case-control study with cluster sampling of controls: application to nonmelanoma skin cancer
    T R Fears
    Biostatistics Branch, National Cancer Institute, Rockville, Maryland 20892 7244, USA
    Biometrics 56:190-8. 2000
    ..The methods presented yield estimates of relative and absolute risk, with standard errors, while accounting naturally for the two-stage sampling of the cohort and cluster sampling of controls...
  28. ncbi The estimation and use of absolute risk for weighing the risks and benefits of selective estrogen receptor modulators for preventing breast cancer
    M H Gail
    National Cancer Institute, Bethesda, Maryland 20892, USA
    Ann N Y Acad Sci 949:286-91. 2001
    ..To weigh various risks and benefits of interventions, there is a need for research to develop such models for a range of health outcomes...
  29. ncbi Using a mixed effects model to estimate geographic variation in cancer rates
    G A Pennello
    Biostatistics Branch, National Cancer Institute, Rockville, Maryland 20892, USA
    Biometrics 55:774-81. 1999
    ..We compare these estimates with other measures of variability. Several examples suggest that the RRSD estimates have advantages compared to other measures of variability...
  30. ncbi Methods for testing familial aggregation of diseases in population-based samples: application to Hodgkin lymphoma in Swedish registry data
    R M Pfeiffer
    National Cancer Institute, Division of Cancer Epidemiology and Genetics, 6120 Executive Blvd, Bethesda, MD, 20892 7244, USA
    Ann Hum Genet 68:498-508. 2004
    ..We compare these methods in analysis of familial aggregation of HL and also present simulations to compare survival analyses with analyses of binary outcome data...
  31. ncbi Two approaches for estimating disease prevalence from population-based registries of incidence and total mortality
    M H Gail
    National Cancer Institute, Division of Cancer Epidemiology and Genetics, Bethesda, Maryland 20892 7244, USA
    Biometrics 55:1137-44. 1999
    ..For less common diseases, such as brain cancer, however, TRM or CM10 and other methods that make stabilizing assumptions may be preferred to CM...
  32. ncbi Soy intake is associated with increased 2-hydroxylation and decreased 16alpha-hydroxylation of estrogens in Asian-American women
    Barbara J Fuhrman
    Epidemiology and Biostatistics Program, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Room 5003, Rockville, MD 20852 7246, USA
    Cancer Epidemiol Biomarkers Prev 18:2751-60. 2009
    ..In a sample of Asian-American women, we investigated the associations of usual adult soy intake with the urinary concentrations of 15 estrogens and estrogen metabolites (EM) measured using liquid chromatography-tandem mass spectrometry...
  33. ncbi Mammographic density does not differ between unaffected BRCA1/2 mutation carriers and women at low-to-average risk of breast cancer
    Gretchen L Gierach
    Hormonal and Reproductive Epidemiology Branch, Division of Cancer Epidemiology and Genetics, Office of Preventive Oncology, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    Breast Cancer Res Treat 123:245-55. 2010
    ..Taking these factors into account did not significantly alter the results of the age/body mass index-adjusted analysis. Our results do not provide support for an independent effect of BRCA1/2 mutation status on mammographic density...
  34. ncbi Average midrange ultraviolet radiation flux and time outdoors predict melanoma risk
    Thomas R Fears
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA
    Cancer Res 62:3992-6. 2002
    ..4%). The association between melanoma risk and average annual UVB flux was strong and consistent for men and for women. The association with total adult hours outdoors was notable for men of all skin types and women who develop a suntan...
  35. ncbi Body mass index, effect modifiers, and risk of pancreatic cancer: a pooled study of seven prospective cohorts
    Li Jiao
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    Cancer Causes Control 21:1305-14. 2010
    ..To investigate whether the positive association of body mass index (BMI, kg/m(2)) with risk of pancreatic cancer is modified by age, sex, smoking status, physical activity, and history of diabetes...
  36. ncbi Estimating the variance of disease-prevalence estimates from population-based registries
    Limin X Clegg
    National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892 8316, USA
    Biometrics 58:684-8. 2002
    ..tend to have below-nominal coverage. For these reasons, we recommend the Poisson method, which also reduces the computational burden considerably...
  37. ncbi Estimating age-specific breast cancer risks: a descriptive tool to identify age interactions
    William F Anderson
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institute of Health, Executive Plaza South 8070, 6120 Executive Plaza Blvd, Rockville, MD 20892 7242, USA
    Cancer Causes Control 18:439-47. 2007
    ..Clarifying age-specific female breast cancer risks and interactions may provide important etiologic clues...
  38. ncbi Using cases to strengthen inference on the association between single nucleotide polymorphisms and a secondary phenotype in genome-wide association studies
    Huilin Li
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Executive Plaza South, Bethesda, Maryland, USA
    Genet Epidemiol 34:427-33. 2010
    ....
  39. ncbi Helicobacter pylori infection in rural China: demographic, lifestyle and environmental factors
    Linda Morris Brown
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
    Int J Epidemiol 31:638-45. 2002
    ..Although Helicobacter pylori is one of the most common human bacterial infections worldwide, its mode of transmission is unclear...
  40. ncbi Associations between alpha-tocopherol, beta-carotene, and retinol and prostate cancer survival
    Joanne L Watters
    Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, Nutritional Epidemiology Branch and Biostatistics Branch, National Cancer Institute, NIH, Bethesda, Maryland 20892, USA
    Cancer Res 69:3833-41. 2009
    ..Further investigations, possibly including randomized studies, are needed to confirm this observation...
  41. ncbi Performance of common genetic variants in breast-cancer risk models
    Sholom Wacholder
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, EPS 5050, MSC 7244, Bethesda, MD 20892, USA
    N Engl J Med 362:986-93. 2010
    ..Genomewide association studies have identified multiple genetic variants associated with breast cancer. The extent to which these variants add to existing risk-assessment models is unknown...
  42. ncbi Efficiency of DNA pooling to estimate joint allele frequencies and measure linkage disequilibrium
    Ruth M Pfeiffer
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, EPS 8030, Bethesda, MD 20892 7244, USA
    Genet Epidemiol 22:94-102. 2002
    ..Our methods allow for imperfect assay sensitivity and specificity. The expected savings in numbers of assays required when pooling is utilized compared to individual testing are quantified...
  43. ncbi A prospective study of red and processed meat intake in relation to cancer risk
    Amanda J Cross
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, Maryland, United States of America
    PLoS Med 4:e325. 2007
    ..We investigated whether red or processed meat intake increases cancer risk at a variety of sites...
  44. ncbi Covariate adjustment and ranking methods to identify regions with high and low mortality rates
    Huilin Li
    Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Executive Plaza South, RM 8034, Bethesda, Maryland 20892, USA
    Biometrics 66:613-20. 2010
    ..However, for diseases with smaller event counts, such as cancers, and wide variation in event counts among regions, EB and PPR methods outperform ranking based on SMRs...
  45. ncbi Postdiagnosis diet quality is inversely related to a biomarker of inflammation among breast cancer survivors
    Stephanie M George
    Yale School of Public Health, Division of Chronic Disease Epidemiology, New Haven, Connecticut, USA
    Cancer Epidemiol Biomarkers Prev 19:2220-8. 2010
    ....
  46. ncbi Impact of population substructure on trend tests for genetic case-control association studies
    Gang Zheng
    Office of Biostatistics Research, DPPS, National Heart, Lung and Blood Institute, 6701 Rockledge Drive, MSC 7913, Bethesda, Maryland 20892 7913, USA
    Biometrics 66:196-204. 2010
    ..Our results provide insight into the properties of some proposed corrections for bias and variance distortion and show why they may not fully correct for the effects of population substructure...
  47. ncbi Colorectal cancer risk prediction tool for white men and women without known susceptibility
    Andrew N Freedman
    Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, EPN 4005 MSC 7344, Bethesda, MD 20892 7344, USA
    J Clin Oncol 27:686-93. 2009
    ....
  48. ncbi Estimation of attributable number of deaths and standard errors from simple and complex sampled cohorts
    Barry I Graubard
    Biostatistics Branch, National Cancer Institute, 6120 Executive Blvd, Room 8024, Bethesda, MD 20892, USA
    Stat Med 26:2639-49. 2007
    ..These methods can also be used to estimate the attributable number of cause-specific deaths and their standard errors when the time period for the accrual of deaths is short...
  49. ncbi Serum cytokine analysis in a positive chemoprevention trial: selenium, interleukin-2, and an association with squamous preneoplastic disease
    Mark J Roth
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7232, USA
    Cancer Prev Res (Phila) 3:810-7. 2010
    ..The favorable effect of selenomethionine on esophageal dysplasia in the original trial may have been mediated in part by its effect in reducing the levels of IL-2...
  50. ncbi A shared susceptibility locus in PLCE1 at 10q23 for gastric adenocarcinoma and esophageal squamous cell carcinoma
    Christian C Abnet
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
    Nat Genet 42:764-7. 2010
    ..19 x 10(-15); OR = 1.57), and for those in the noncardia stomach it was absent (P = 0.44; OR = 1.05). Our findings at 10q23 could provide insight into the high incidence of both cancers in China...
  51. ncbi Comparison of asbestos exposure assessments by next-of-kin respondents, by an occupational hygienist, and by a job-exposure matrix from the National Occupational Hazard Survey
    Jun Mo Nam
    Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
    Am J Ind Med 47:443-50. 2005
    ..Assessments of occupational exposures in case-control studies of rapidly fatal illnesses often rely on data from next-of-kin respondents, which may be inaccurate...
  52. ncbi Robustness of inference on measured covariates to misspecification of genetic random effects in family studies
    Ruth M Pfeiffer
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892 7244, USA
    Genet Epidemiol 24:14-23. 2003
    ..The model is applied to data from a family study on nasopharyngeal carcinoma in Taiwan...
  53. ncbi Estimates of the number of US women who could benefit from tamoxifen for breast cancer chemoprevention
    Andrew N Freedman
    Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 7344, USA
    J Natl Cancer Inst 95:526-32. 2003
    ..67% or higher for breast cancer chemoprevention. However, tamoxifen use has been associated with adverse outcomes, and not all eligible women have a positive benefit/risk ratio...
  54. ncbi Sample size calculations for population- and family-based case-control association studies on marker genotypes
    Ruth M Pfeiffer
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892 7244, USA
    Genet Epidemiol 25:136-48. 2003
    ..The large sample-size requirements represent a formidable challenge to studies of this type...
  55. ncbi Postdiagnosis diet quality, the combination of diet quality and recreational physical activity, and prognosis after early-stage breast cancer
    Stephanie M George
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Suite 320, MSC 7232, Rockville, MD 20852, USA
    Cancer Causes Control 22:589-98. 2011
    ..To investigate, among women with breast cancer, how postdiagnosis diet quality and the combination of diet quality and recreational physical activity are associated with prognosis...
  56. ncbi Familial aggregation of Hodgkin lymphoma and related tumors
    Lynn R Goldin
    Genetic Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892 7236, USA
    Cancer 100:1902-8. 2004
    ..However, the spectrum of malignancies associated with common genetic etiology and the effects of gender and age on familial risk have not been established...
  57. ncbi Cancer burden in the HIV-infected population in the United States
    Meredith S Shiels
    Infections and Immunoepidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD 20852, USA
    J Natl Cancer Inst 103:753-62. 2011
    ..We estimated the annual number of cancers in the HIV-infected population, both with and without AIDS, in the United States...
  58. ncbi Some of Sam Greenhouse's contributions to statistical methods
    Mitchell H Gail
    Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Room EPS 8032, Bethesda, MD 20892 7244, USA
    Stat Med 22:3301-8. 2003
    ..Many of his papers continue to provide important guidance and insight because he dealt with issues of enduring practical importance...
  59. ncbi Prevalence of hepatitis C virus infection and risk for hepatocellular carcinoma and non-Hodgkin lymphoma in AIDS
    Eric A Engels
    Viral Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute NIH, 6120 Executive Boulevard, EPS 8010, Rockville, MD 20892, USA
    J Acquir Immune Defic Syndr 31:536-41. 2002
    ..These data suggest an effect of HCV infection on HCC risk among adults with AIDS. On the other hand, NHL risk was not higher for groups in whom HCV infection was prevalent...
  60. ncbi Disinfection of endoscopes from Helicobacter pylori-positive subjects: evaluation of the effectiveness of the Chinese Calijing disinfection kit
    Linda Morris Brown
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892 7244, USA
    Am J Infect Control 33:197-201. 2005
    ....
  61. ncbi Five-year and lifetime risk of breast cancer among U.S. subpopulations: implications for magnetic resonance imaging screening
    Barry I Graubard
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA
    Cancer Epidemiol Biomarkers Prev 19:2430-6. 2010
    ..Because MRI screening is costly and has limited specificity, estimates of the numbers of U.S. women with ≥20% breast cancer risk would be useful...
  62. ncbi Validation of a model of lung cancer risk prediction among smokers
    Kathleen A Cronin
    Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD, USA
    J Natl Cancer Inst 98:637-40. 2006
    ..57 (95% CI = 0.49 to 0.67) for the age groups 50-54, 55-59, 60-64, and 65-69 years, respectively. Periodic radiographic screening in the ATBC Study may explain why slightly more cancers were observed than expected from the Bach model...
  63. ncbi Case-control and case-only designs with genotype and family history data: estimating relative risk, residual familial aggregation, and cumulative risk
    Nilanjan Chatterjee
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, 6210 Executive Boulevard, Rockville, Maryland 20852, USA
    Biometrics 62:36-48. 2006
    ..We illustrate the proposed methodologies by estimating the risk of breast cancer from BRCA1/2 mutations using data from the Washington Ashkenazi Study...
  64. ncbi Serum antibodies to Helicobacter pylori and the CagA antigen do not explain differences in the prevalence of precancerous gastric lesions in two Chinese populations with contrasting gastric cancer rates
    Frank D Groves
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892 7244, USA
    Cancer Epidemiol Biomarkers Prev 11:1091-4. 2002
    ..Only a relatively small proportion of the difference in prevalence of APGL between these two rural Chinese populations can be explained by differences in H. pylori or CagA seroprevalence...
  65. ncbi Cumulative absolute breast cancer risk for young women treated for Hodgkin lymphoma
    Lois B Travis
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    J Natl Cancer Inst 97:1428-37. 2005
    ..We estimated this future risk, taking into account age and calendar year of HL diagnosis, HL treatment information, population breast cancer incidence rates, and competing causes of death...
  66. ncbi Beyond recreational physical activity: examining occupational and household activity, transportation activity, and sedentary behavior in relation to postmenopausal breast cancer risk
    Stephanie M George
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, MD, USA
    Am J Public Health 100:2288-95. 2010
    ..We prospectively examined nonrecreational physical activity and sedentary behavior in relation to breast cancer risk among 97 039 postmenopausal women in the National Institutes of Health-AARP Diet and Health Study...
  67. ncbi Cancer risk prediction models: a workshop on development, evaluation, and application
    Andrew N Freedman
    Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD 20892 7344, USA
    J Natl Cancer Inst 97:715-23. 2005
    ....
  68. ncbi Statistical properties of Teng and Risch's sibship type tests for detecting an association between disease and a candidate allele
    Z Li
    Department of Statistics, The Biostatistics Center, George Washington University, Rockville, MD 20852, USA
    Hum Hered 53:114-29. 2002
    ..One of them incorporates an estimate of the null variance obtained from an auxiliary sample and appears to noticeably decrease the sample sizes required to achieve a prespecified power...
  69. ncbi Validation of a colorectal cancer risk prediction model among white patients age 50 years and older
    Yikyung Park
    Division of Cancer Epidemiology and Genetics, Biostatistics Branch, Bethesda, MD 20852, USA
    J Clin Oncol 27:694-8. 2009
    ..Validation of an absolute risk prediction model for colorectal cancer (CRC) by using a large, population-based cohort...
  70. ncbi Cancer in Korean war navy technicians: mortality survey after 40 years
    Frank D Groves
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
    Am J Epidemiol 155:810-8. 2002
    ..2, 95% CI: 1.3, 3.7). Radar exposure had little effect on mortality in this cohort of US Navy veterans...
  71. ncbi Correcting bias, or biased corrections?
    Katherine M Flegal
    National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, MD, USA
    Obesity (Silver Spring) 16:229-31. 2008
  72. ncbi Quantifying estrogen metabolism: an evaluation of the reproducibility and validity of enzyme immunoassays for 2-hydroxyestrone and 16alpha-hydroxyestrone in urine
    R G Ziegler
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892, USA
    Environ Health Perspect 105:607-14. 1997
    ..Accordingly, more sensitive EIAs have been developed and are now being evaluated...
  73. ncbi Projecting individualized absolute invasive breast cancer risk in Asian and Pacific Islander American women
    Rayna K Matsuno
    Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7244, USA
    J Natl Cancer Inst 103:951-61. 2011
    ..We developed a model for projecting absolute invasive breast cancer risk in APA women and compared its projections to those from BCRAT...
  74. ncbi Increasing breast cancer incidence in China: the numbers add up
    Regina G Ziegler
    J Natl Cancer Inst 100:1339-41. 2008
  75. ncbi Risk of contralateral testicular cancer: a population-based study of 29,515 U.S. men
    Sophie D Fossa
    Department of Clinical Cancer Research, The Norwegian Radium Hospital, University of Oslo, Norway
    J Natl Cancer Inst 97:1056-66. 2005
    ..We evaluated the risk of contralateral testicular cancer and survival in a large population-based cohort of men diagnosed with testicular cancer before age 55 years...
  76. ncbi Excess deaths associated with underweight, overweight, and obesity
    Katherine M Flegal
    National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, MD 20782, USA
    JAMA 293:1861-7. 2005
    ..As the prevalence of obesity increases in the United States, concern over the association of body weight with excess mortality has also increased...
  77. ncbi Genetic polymorphisms of CYP2E1, GSTT1, GSTP1, GSTM1, ALDH2, and ODC and the risk of advanced precancerous gastric lesions in a Chinese population
    Wei Cheng You
    Peking University School of Oncology, Beijing Cancer Hospital and Beijing Institute for Cancer Research, 52 Fu Cheng Road, Haidian District, Beijing 100036, People s Republic of China
    Cancer Epidemiol Biomarkers Prev 14:451-8. 2005
    ..These polymorphisms do not seem to govern progression from mild chronic atrophic gastritis to advanced precancerous gastric lesions, but the effects of smoking may be accentuated in individuals carrying variants of CYP2E1...
  78. ncbi Diet and stomach cancer risk in Warsaw, Poland
    Jolanta Lissowska
    Division of Cancer Epidemiology and Prevention, Cancer Center and M Sklodowska Curie Institute of Oncology, Warsaw, Poland
    Nutr Cancer 48:149-59. 2004
    ..Our data also suggest that high carbohydrate consumption may influence risk, but further confirmation is needed...
  79. ncbi Population-density and county-level variation in breast cancer mortality rates among white women residing in the Northeastern and Southern United States
    Susan R Sturgeon
    Department of Biostatistics and Epidemiology, School of Public Health and Health Sciences, University of Massachusetts, Amherst, MA 01003, USA
    Cancer Causes Control 14:923-31. 2003
    ..We assessed the contribution of variation in risk factor prevalence to population-density and county-level variation in breast cancer mortality rates...
  80. ncbi Haplotype analysis in population genetics and association studies
    Hongyu Zhao
    Department of Epidemiology and Public Health, Yale University School of Medicine, New Haven, CT 06520, USA
    Pharmacogenomics 4:171-8. 2003
    ....
  81. ncbi Dominant role of hepatitis B virus and cofactor role of aflatoxin in hepatocarcinogenesis in Qidong, China
    Lihua Ming
    National Laboratory of Molecular Oncology, Cancer Institute, Chinese Academy of Medical Sciences, Beijing, China
    Hepatology 36:1214-20. 2002
    ..The 249ser-p53 mutation appears to result from coexposure to aflatoxin and HBV infection. Even modest levels of aflatoxin exposure tripled the risk of HCC in HBV-infected men...
  82. ncbi Projecting absolute invasive breast cancer risk in white women with a model that includes mammographic density
    Jinbo Chen
    Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    J Natl Cancer Inst 98:1215-26. 2006
    ..CONCLUSIONS: This new model for absolute invasive breast cancer risk in white women promises modest improvements in discriminatory power compared with the Gail model but needs to be validated with independent data...
  83. ncbi Randomized double-blind factorial trial of three treatments to reduce the prevalence of precancerous gastric lesions
    Wei-cheng You
    Peking University School of Oncology, Beijing Cancer Hospital and Beijing Institute for Cancer Research, Beijing, China
    J Natl Cancer Inst 98:974-83. 2006
    ..Long-term vitamin or garlic supplementation had no beneficial effects on the prevalence of precancerous gastric lesions or on gastric cancer incidence...
  84. ncbi Weight-associated deaths in the United States
    Katherine M Flegal
    J Womens Health (Larchmt) 16:1368-70. 2007
  85. ncbi Absolute risk models for subtypes of breast cancer
    Mitchell H Gail
    J Natl Cancer Inst 99:1657-9. 2007
  86. ncbi Cause-specific excess deaths associated with underweight, overweight, and obesity
    Katherine M Flegal
    National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, MD 20782, USA
    JAMA 298:2028-37. 2007
    ..The association of body mass index (BMI) with cause-specific mortality has not been reported for the US population...
  87. ncbi Re: All-cause mortality in randomized trials of cancer screening
    Mitchell H Gail
    J Natl Cancer Inst 94:862; author reply 865-6. 2002
  88. ncbi Garlic, vitamin, and antibiotic treatment for Helicobacter pylori: a randomized factorial controlled trial
    Mitchell H Gail
    Helicobacter 12:575-8. 2007
  89. ncbi Impact of smoking and preexisting illness on estimates of the fractions of deaths associated with underweight, overweight, and obesity in the US population
    Katherine M Flegal
    National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, MD 20782, USA
    Am J Epidemiol 166:975-82. 2007
    ..These analyses suggest that residual confounding by smoking or preexisting illness had little effect on previous estimates of attributable fractions from nationally representative data with measured heights and weights...
  90. ncbi Gail model for prediction of absolute risk of invasive breast cancer: independent evaluation in the Florence-European Prospective Investigation Into Cancer and Nutrition cohort
    Adriano Decarli
    Medical Statistics and Biometry Institute, University of Milan, Via Venezian 1, 20133 Milan, Italy
    J Natl Cancer Inst 98:1686-93. 2006
    ..Although the GM has been validated in US populations, its performance in other populations is unclear because of the wide variation in international breast cancer rates...
  91. ncbi A randomized factorial study of the effects of long-term garlic and micronutrient supplementation and of 2-wk antibiotic treatment for Helicobacter pylori infection on serum cholesterol and lipoproteins
    Lian Zhang
    Beijing Institute for Cancer Research, Beijng, China
    Am J Clin Nutr 84:912-9. 2006
    ..3 y...
  92. ncbi Lifetime data analysis. Editorial
    David Harrington
    Lifetime Data Anal 14:1-5. 2008
  93. ncbi Norman Breslow, an architect of modern biostatistics
    Nick E Day
    Epidemiology, University of Cambridge, Cambridge, UK
    Lifetime Data Anal 13:435-8. 2007