Affiliation: National Institutes of Health
- Risk-based recommendations for mammographic screening for women in their fortiesM Gail
National Cancer Institute, Division of Cancer Epidemiology and Genetics, Rockville, MD 20892, USA
J Clin Oncol 16:3105-14. 1998..To develop risk-based recommendations for mammographic screening for women in their 40s that take into account the woman's age, race, and specific risk factors...
- Designing studies to estimate the penetrance of an identified autosomal dominant mutation: cohort, case-control, and genotyped-proband designsM H Gail
Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20892 7368, USA
Genet Epidemiol 16:15-39. 1999....
- Estrogen replacement therapy and breast cancer survival in a large screening studyC Schairer
Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7374, USA
J Natl Cancer Inst 91:264-70. 1999..We examined breast cancer mortality among women who were diagnosed with axillary lymph node-negative and node-positive breast cancer according to the currency of estrogen use at diagnosis...
- Methods for testing familial aggregation of diseases in population-based samples: application to Hodgkin lymphoma in Swedish registry dataR M Pfeiffer
National Cancer Institute, Division of Cancer Epidemiology and Genetics, 6120 Executive Blvd, Bethesda, MD, 20892 7244, USA
Ann Hum Genet 68:498-508. 2004..We compare these methods in analysis of familial aggregation of HL and also present simulations to compare survival analyses with analyses of binary outcome data...
- Power and related statistical properties of conditional likelihood score tests for association studies in nuclear families with parental genotypesZ Li
Department of Statistics, George Washington University, 2201 G Street NW, Washington, DC 20052, USA
Ann Hum Genet 69:296-314. 2005..Because we derive explicit formulae for all components of the likelihood, we are able to present tables giving required sample sizes for dominant, additive and recessive inheritance models...
- Probability that a two-stage genome-wide association study will detect a disease-associated snp and implications for multistage designsM H Gail
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892 7244, US
Ann Hum Genet 72:812-20. 2008..g. pi(sample)<or= 0.25) should be avoided, and that additional genotyping in earlier studies with small first stages will yield previously unselected disease-associated SNPs...
- Statistical properties of Teng and Risch's sibship type tests for detecting an association between disease and a candidate alleleZ Li
Department of Statistics, The Biostatistics Center, George Washington University, Rockville, MD 20852, USA
Hum Hered 53:114-29. 2002..One of them incorporates an estimate of the null variance obtained from an auxiliary sample and appears to noticeably decrease the sample sizes required to achieve a prespecified power...