Research Topics
Species | Shahinaz M GadallaSummaryAffiliation: National Institutes of Health Country: USA Publications
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Publications
Telomere biology in hematopoiesis and stem cell transplantationShahinaz M Gadalla
Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20852, USA
Blood Rev 25:261-9. 2011..g., cord blood). Telomere attrition may play a role in, or be a marker of, long term outcome after HSCT, but these data are limited. In this review, we discuss telomere biology in normal and abnormal hematopoiesis, including HSCT...
The relationship between DNA methylation and telomere length in dyskeratosis congenitaShahinaz M Gadalla
Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD 20852, USA
Aging Cell 11:24-8. 2012..17), subtelomeric (r = -0.20) were present in unaffected relatives. This study suggests an interaction between TL and both subtelomeric and LINE-1 methylation, which may be altered based on mutation status of telomere biology genes...
LINE-1 methylation is inherited in familial testicular cancer kindredsLisa Mirabello
Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
BMC Med Genet 11:77. 2010..Global DNA hypomethylation has been associated with the risk of cancers of the bladder and head/neck...
Telomere length in blood, buccal cells, and fibroblasts from patients with inherited bone marrow failure syndromesShahinaz M Gadalla
Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD 20852, USA
Aging (Albany NY) 2:867-74. 2010..66, p=0.002), blood and buccal cells (r=0.74, p<0.0001), and fibroblast and buccal cells (r=0.65, p=0.004). These data suggest that relative TL is tissue-independent in DC and possibly in the other IBMFS...
