Ana Gabrea

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. pmc Secondary genomic rearrangements involving immunoglobulin or MYC loci show similar prevalences in hyperdiploid and nonhyperdiploid myeloma tumors
    Ana Gabrea
    Genetics Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, USA
    Genes Chromosomes Cancer 47:573-90. 2008
  2. ncbi request reprint Distinguishing primary and secondary translocations in multiple myeloma
    Ana Gabrea
    National Cancer Institute, Bethesda, MD 20889 5105, USA
    DNA Repair (Amst) 5:1225-33. 2006
  3. ncbi request reprint Complex rearrangements involving der(8)t(8;20) and der(14)t(8;14)t(11;14), CCND1, and duplication of IgH constant region in acute plasmablastic leukemia
    Turid Knutsen
    Genetics Branch, Center for Clinical Research, National Cancer Institute, 50 South Drive, Room 1408, Bethesda, MD 20892 8010, USA
    Cancer Genet Cytogenet 164:137-41. 2006
  4. pmc Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma
    Christina M Annunziata
    Metabolism Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA
    Cancer Cell 12:115-30. 2007

Detail Information

Publications4

  1. pmc Secondary genomic rearrangements involving immunoglobulin or MYC loci show similar prevalences in hyperdiploid and nonhyperdiploid myeloma tumors
    Ana Gabrea
    Genetics Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, USA
    Genes Chromosomes Cancer 47:573-90. 2008
    ..We conclude that IG light chain and MYC rearrangements, as well as secondary IGH rearrangements, make similar contributions to the progression of both HRD and NHRD MM tumors...
  2. ncbi request reprint Distinguishing primary and secondary translocations in multiple myeloma
    Ana Gabrea
    National Cancer Institute, Bethesda, MD 20889 5105, USA
    DNA Repair (Amst) 5:1225-33. 2006
    ..It is hypothesized that secondary translocations not involving a MYC gene can occur at any stage of tumorigenesis, including in pre-malignant MGUS tumor cells...
  3. ncbi request reprint Complex rearrangements involving der(8)t(8;20) and der(14)t(8;14)t(11;14), CCND1, and duplication of IgH constant region in acute plasmablastic leukemia
    Turid Knutsen
    Genetics Branch, Center for Clinical Research, National Cancer Institute, 50 South Drive, Room 1408, Bethesda, MD 20892 8010, USA
    Cancer Genet Cytogenet 164:137-41. 2006
    ..2;p?12) and der(14)t(8;14)(p?;p11.2)t(11;14)(q13;q32), with juxtaposition of CH (constant region of IgH) sequences to the oncogene CCND1 (translocated to 14q32). FISH analysis demonstrated that the CH on the der(14) was duplicated...
  4. pmc Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma
    Christina M Annunziata
    Metabolism Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA
    Cancer Cell 12:115-30. 2007
    ..These data demonstrate that addiction to the NF-kappaB pathway is frequent in myeloma and suggest that IKKbeta inhibitors hold promise for the treatment of this disease...